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The map label for this gene is rnhB

Identifier: 114331990

GI number: 114331990

Start: 2139707

End: 2140366

Strand: Reverse

Name: rnhB

Synonym: Neut_2024

Alternate gene names: 114331990

Gene position: 2140366-2139707 (Counterclockwise)

Preceding gene: 114331991

Following gene: 114331989

Centisome position: 80.43

GC content: 48.94

Gene sequence:

>660_bases
GTGTACTGCTCGGGCCATCTGATTCGGTTAGCAGGGAGGTTAGAAATCAAGACTTCTGGTGTCGTCGTTCGAGAATGGAT
CCATCCGGAAGGGAAAGCTATCTACGGGGTGGATGAAGCTGGTAGGGGGCCGCTAGCTGGTCCGGTCTATGCTGCGTGTG
TTGTGCTGGATTCTTGCTACGTTATCAATGGACTGGCGGATTCCAAACAGTTAAGTGAAAAACGGCGGGCCAGTTTGGCC
GAACAAATAAAACAGCATGCTCGCGCATGGGCAATTGCTTCAGCCTCAGTGGAGGAGATTGATCGGCTGAATATTTTACA
AGCCAGCATGCTCGCAATGCGAAGAGCAGTCATTGAATTAATGCCGGTGTCTAATGCACTAATTCTGGTAGATGGCACCC
ATGTACCACAACTGGATTATGAAGTGCAGGCAGTTATCAGAGGAGATAGTCTGGTAGCTGAGATTTCGGCAGCCTCAATT
CTTGCCAAAACTGCGAGGGATGCAGAAATGTTACGGCTACACGAGATTTACCCGATTTATGGTTTTGATCGACATAAAGG
CTATCCCACCAGAGTGCACTTGGACGCAATTCGTTTGCATGGAATAACAGCTACTCATCGCAAAAGTTTCGCGCCGTGTG
CTGAGAAATCAACGGTGTGA

Upstream 100 bases:

>100_bases
TGGTATTAAAGGTTGAAATCACCCGTCAGCTGAAAGGAATTTGGAAATATTCAGCCTGTGCAGAAGTGGATGGCCAGCTT
GTCACCGAAGCTCAGCTGAT

Downstream 100 bases:

>100_bases
TTTTAAACAAATTTTATCAACTGGTTACCTCGAAAAACCCTGTTTTTGAAAATCCATTGATCGTAAACTCAATGTGTTAC
ATACAAATCTCTTCAGAATT

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MYCSGHLIRLAGRLEIKTSGVVVREWIHPEGKAIYGVDEAGRGPLAGPVYAACVVLDSCYVINGLADSKQLSEKRRASLA
EQIKQHARAWAIASASVEEIDRLNILQASMLAMRRAVIELMPVSNALILVDGTHVPQLDYEVQAVIRGDSLVAEISAASI
LAKTARDAEMLRLHEIYPIYGFDRHKGYPTRVHLDAIRLHGITATHRKSFAPCAEKSTV

Sequences:

>Translated_219_residues
MYCSGHLIRLAGRLEIKTSGVVVREWIHPEGKAIYGVDEAGRGPLAGPVYAACVVLDSCYVINGLADSKQLSEKRRASLA
EQIKQHARAWAIASASVEEIDRLNILQASMLAMRRAVIELMPVSNALILVDGTHVPQLDYEVQAVIRGDSLVAEISAASI
LAKTARDAEMLRLHEIYPIYGFDRHKGYPTRVHLDAIRLHGITATHRKSFAPCAEKSTV
>Mature_219_residues
MYCSGHLIRLAGRLEIKTSGVVVREWIHPEGKAIYGVDEAGRGPLAGPVYAACVVLDSCYVINGLADSKQLSEKRRASLA
EQIKQHARAWAIASASVEEIDRLNILQASMLAMRRAVIELMPVSNALILVDGTHVPQLDYEVQAVIRGDSLVAEISAASI
LAKTARDAEMLRLHEIYPIYGFDRHKGYPTRVHLDAIRLHGITATHRKSFAPCAEKSTV

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=189, Percent_Identity=52.3809523809524, Blast_Score=195, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_NITEC (Q0AEI5)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748212.1
- ProteinModelPortal:   Q0AEI5
- SMR:   Q0AEI5
- STRING:   Q0AEI5
- GeneID:   4273236
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_2024
- NMPDR:   fig|335283.3.peg.2485
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- PhylomeDB:   Q0AEI5
- ProtClustDB:   PRK00015
- BioCyc:   NEUT335283:NEUT_2024-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 24020; Mature: 24020

Theoretical pI: Translated: 8.33; Mature: 8.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYCSGHLIRLAGRLEIKTSGVVVREWIHPEGKAIYGVDEAGRGPLAGPVYAACVVLDSCY
CCCCCEEEEEEEEEEEEECCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
VINGLADSKQLSEKRRASLAEQIKQHARAWAIASASVEEIDRLNILQASMLAMRRAVIEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MPVSNALILVDGTHVPQLDYEVQAVIRGDSLVAEISAASILAKTARDAEMLRLHEIYPIY
CCCCCEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEC
GFDRHKGYPTRVHLDAIRLHGITATHRKSFAPCAEKSTV
CCCCCCCCCCEEEEEEEEEECCCHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MYCSGHLIRLAGRLEIKTSGVVVREWIHPEGKAIYGVDEAGRGPLAGPVYAACVVLDSCY
CCCCCEEEEEEEEEEEEECCEEEEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHH
VINGLADSKQLSEKRRASLAEQIKQHARAWAIASASVEEIDRLNILQASMLAMRRAVIEL
EECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHH
MPVSNALILVDGTHVPQLDYEVQAVIRGDSLVAEISAASILAKTARDAEMLRLHEIYPIY
CCCCCEEEEEECCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHCCEEC
GFDRHKGYPTRVHLDAIRLHGITATHRKSFAPCAEKSTV
CCCCCCCCCCEEEEEEEEEECCCHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA