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The map label for this gene is fabZ [H]

Identifier: 114331991

GI number: 114331991

Start: 2140345

End: 2140788

Strand: Reverse

Name: fabZ [H]

Synonym: Neut_2025

Alternate gene names: 114331991

Gene position: 2140788-2140345 (Counterclockwise)

Preceding gene: 114331992

Following gene: 114331990

Centisome position: 80.45

GC content: 47.3

Gene sequence:

>444_bases
ATGGCTGTGATGGATATCCATGAAATACTGAAATACTTGCCGCATCGTTATCCACTGATTCTGGTTGATCGGGTGGTTTC
ACTTGAGTTGGGCAAGCGGATTCACGCATACAAGAATGTTTCTATCAATGAGCCTTATTTTTCCGGACATTTTCCGCATC
ATCCGGTGATGCCGGGAGTATTGATTGTTGAAGCACTGGCGCAGGCAGCTGCCTTGCTGACGATTCGATCAGAAAATATG
GAAAAAGATGCCGGACAGGTGTATTACTTCGTGGGTATCGACGGAGTACGATTCAAAAAGCCGGTTATCGCGGGTGATCA
GCTGGTATTAAAGGTTGAAATCACCCGTCAGCTGAAAGGAATTTGGAAATATTCAGCCTGTGCAGAAGTGGATGGCCAGC
TTGTCACCGAAGCTCAGCTGATGTGTACTGCTCGGGCCATCTGA

Upstream 100 bases:

>100_bases
GTATTGATATTACTGACCAGGTGATCAAGGCATTAAACGCACAGGAACCGACTTCCAGGAAACAATAAATATATAAAAAT
TTGTATAACAGAGAGATAGA

Downstream 100 bases:

>100_bases
TTCGGTTAGCAGGGAGGTTAGAAATCAAGACTTCTGGTGTCGTCGTTCGAGAATGGATCCATCCGGAAGGGAAAGCTATC
TACGGGGTGGATGAAGCTGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 147; Mature: 146

Protein sequence:

>147_residues
MAVMDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGVLIVEALAQAAALLTIRSENM
EKDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKGIWKYSACAEVDGQLVTEAQLMCTARAI

Sequences:

>Translated_147_residues
MAVMDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGVLIVEALAQAAALLTIRSENM
EKDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKGIWKYSACAEVDGQLVTEAQLMCTARAI
>Mature_146_residues
AVMDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGVLIVEALAQAAALLTIRSENME
KDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKGIWKYSACAEVDGQLVTEAQLMCTARAI

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=140, Percent_Identity=48.5714285714286, Blast_Score=158, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16501; Mature: 16369

Theoretical pI: Translated: 8.23; Mature: 8.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAVMDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGV
CCCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCHH
LIVEALAQAAALLTIRSENMEKDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKG
HHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCEECCCEECCCEEEEEEEEHHHHHH
IWKYSACAEVDGQLVTEAQLMCTARAI
HHHHHHHHHCCCCHHHHHHHHHHCCCC
>Mature Secondary Structure 
AVMDIHEILKYLPHRYPLILVDRVVSLELGKRIHAYKNVSINEPYFSGHFPHHPVMPGV
CCCHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCCCCCHH
LIVEALAQAAALLTIRSENMEKDAGQVYYFVGIDGVRFKKPVIAGDQLVLKVEITRQLKG
HHHHHHHHHHHHEEECCCCCCCCCCCEEEEEECCCCEECCCEECCCEEEEEEEEHHHHHH
IWKYSACAEVDGQLVTEAQLMCTARAI
HHHHHHHHHCCCCHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]