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The map label for this gene is slyD [H]

Identifier: 114331989

GI number: 114331989

Start: 2139072

End: 2139551

Strand: Reverse

Name: slyD [H]

Synonym: Neut_2023

Alternate gene names: 114331989

Gene position: 2139551-2139072 (Counterclockwise)

Preceding gene: 114331990

Following gene: 114331970

Centisome position: 80.4

GC content: 46.46

Gene sequence:

>480_bases
ATGCGCATAGTAAAAAATACGGTGGTATCACTCCACTATAAAATGACCGATCAGGAAGGAAATCTGATGGAAGAAACTGA
TGAACCCATCAGCTACTTGCATGGTGGTTATGATGGAATATTTCCAGTAGTGGAAGAAGCGCTGCATGAAAAAGAAACCG
GGGCAACCTTATCCCTGCAAATGGAACCGGATGATGCTTTTGGAGAATATGATGAGGAACTGATGCGCGTTGAGCCACGT
AGTGCGTTCCCGGAAGAAATCACGGTCGGGATGCAATTTGAGGGGGGTGAGGAAGATTCTGATGATTTTTATATCTATAC
AGTGAGAGAGATCACTGATGATGTCGTGGTAGTGGATGGTAATCATCCCTACGCTGGTATGGCATTTCAGTTTGAATGCA
CAGTTACGGAAGTACGCCCGGCAACGGAAGAAGAATTATCTCACGGACATGTACACGGGCCGCACGGCCACGAGCATTAG

Upstream 100 bases:

>100_bases
ATTGATCGTAAACTCAATGTGTTACATACAAATCTCTTCAGAATTTATAGGTTTTTCGAGGTGCCCAACTACAAGGAAGC
CTGATTCAGGCAGAGGAAGC

Downstream 100 bases:

>100_bases
ACGATCTCACCAGCATTTTTCACCATCTTGTTAATTATTTTATCCGATTGGCCATTGATTTAATGAGGTAAAGCTGTTCC
AGTGCCTCCCGGGGAGTCAG

Product: FKBP-type peptidyl-prolyl cis-trans isomerase (PPIase)

Products: NA

Alternate protein names: PPIase; Metallochaperone slyD [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MRIVKNTVVSLHYKMTDQEGNLMEETDEPISYLHGGYDGIFPVVEEALHEKETGATLSLQMEPDDAFGEYDEELMRVEPR
SAFPEEITVGMQFEGGEEDSDDFYIYTVREITDDVVVVDGNHPYAGMAFQFECTVTEVRPATEEELSHGHVHGPHGHEH

Sequences:

>Translated_159_residues
MRIVKNTVVSLHYKMTDQEGNLMEETDEPISYLHGGYDGIFPVVEEALHEKETGATLSLQMEPDDAFGEYDEELMRVEPR
SAFPEEITVGMQFEGGEEDSDDFYIYTVREITDDVVVVDGNHPYAGMAFQFECTVTEVRPATEEELSHGHVHGPHGHEH
>Mature_159_residues
MRIVKNTVVSLHYKMTDQEGNLMEETDEPISYLHGGYDGIFPVVEEALHEKETGATLSLQMEPDDAFGEYDEELMRVEPR
SAFPEEITVGMQFEGGEEDSDDFYIYTVREITDDVVVVDGNHPYAGMAFQFECTVTEVRPATEEELSHGHVHGPHGHEH

Specific function: Also involved in hydrogenase metallocenter assembly, probably by participating in the nickel insertion step. This function in hydrogenase biosynthesis requires chaperone activity and the presence of the metal-binding domain, but not PPIase activity [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789748, Length=152, Percent_Identity=37.5, Blast_Score=88, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17992; Mature: 17992

Theoretical pI: Translated: 4.02; Mature: 4.02

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIVKNTVVSLHYKMTDQEGNLMEETDEPISYLHGGYDGIFPVVEEALHEKETGATLSLQ
CCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEE
MEPDDAFGEYDEELMRVEPRSAFPEEITVGMQFEGGEEDSDDFYIYTVREITDDVVVVDG
ECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEC
NHPYAGMAFQFECTVTEVRPATEEELSHGHVHGPHGHEH
CCCCCCEEEEEEEEEEECCCCCHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MRIVKNTVVSLHYKMTDQEGNLMEETDEPISYLHGGYDGIFPVVEEALHEKETGATLSLQ
CCCCCCEEEEEEEEEECCCCCCCCCCCCHHHHHHCCCCCHHHHHHHHHHHHCCCCEEEEE
MEPDDAFGEYDEELMRVEPRSAFPEEITVGMQFEGGEEDSDDFYIYTVREITDDVVVVDG
ECCCCCCCHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCCCCEEEEEEECCCCCEEEEEC
NHPYAGMAFQFECTVTEVRPATEEELSHGHVHGPHGHEH
CCCCCCEEEEEEEEEEECCCCCHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]