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The map label for this gene is 114331962

Identifier: 114331962

GI number: 114331962

Start: 2110378

End: 2111403

Strand: Reverse

Name: 114331962

Synonym: Neut_1996

Alternate gene names: NA

Gene position: 2111403-2110378 (Counterclockwise)

Preceding gene: 114331963

Following gene: 114331961

Centisome position: 79.34

GC content: 56.63

Gene sequence:

>1026_bases
ATGAATATTCAAAATCAGTTGCAGGCAACCGTCGAGGCGTTAGTACAGCAGGGCAAAGGTATCCTGGCCATGGATGAAAG
CAGCCCGACGATCGCGAAACGCTTCAAACCAATCGGGGTGGAATCAACCGAGGAAAATCGCCGCAGTTACCGCAGCATGT
TATTGGCAACACCGGGTCTCGGTGAATTTGTCAGCGGTGTTATCTTGTTTGAGGAAACCCTCGGGCAAAAAGCGGATGAC
GGTACTCCGTTGCCGGCGCTCGCCGCGCAACAAGGCATTGTGCCGGGCATCAAGGTCGATAAGGGTAAACTCGCGTTGGC
CAATGCGCCTGGGGATGAAATCACCGAAGGTCTGGATGGTCTGGCACTGCGTTTGGAGAGCTACAAGCAGCAGGGCGCAC
GATTCGCCAAATGGCGTGATGTGTACCACATCTCCGCAACCACCCCGAGCCGGTTGGCCATCGAGGCCAATGCCGAGGTC
TTGGCGCGGTATGCCTCTATCTGCCAGACGCTGGGCATTGTGCCCATCGTTGAACCCGAAGTGCTCATCGATGGCGATCA
CAGCATCGACCGATGCGCTGAAGTCACTGAAGCGGTGCTGCATGAAGTATTTCATGCATTACACTGCTATCACGTAATTT
TGGAGCATATGCTGCTGAAGCCCAACATGGTAATCCCGGGTAAAACGCACGCCCAGAAGGCCAGCCCGGAGGAGGTGGCT
GAGCAGACGATCAGGGTACTGCGGCGCACCGTGCCGGCGGCTGTCCCCAGCATCAATTTTCTGTCTGGTGGGCTGACTCC
GGAGGAGGCGACTGCCAATCTCAATGCCATGAATTGTCTGGCACCGCAACCCTGGGACCTGAGTTTCTCGTACGGCCGTG
CATTGCAGCAGCCTGCCTTACAGGCCTGGAAAGGCAATGCAGGTAATGCCGCAAGTACTCAGGCTGCACTCTATCTGCGT
GCCAAACTCAACGGTGCCGCACGTCATGGCAGCTATAGTGTCACGATGGAGCCAGCGCAGGAGTGA

Upstream 100 bases:

>100_bases
AAAGAGAATTTACTTTTCTTGTGTCTCTCACCCGTCCGGGCTCTTAAAGTAGTTCCCACCAAAGATCCGGTTTGATGTTT
AAGCCGCAAAGAGGATGCTC

Downstream 100 bases:

>100_bases
AAAATCGGTGAATAGGCGCGTTTGGGAACTGCATAAGTTATTCTATTCATAGCCGAGCTTGGCTGTACTCAGGCCACGGC
CCGGAATGATATATCTTGGT

Product: fructose-bisphosphate aldolase

Products: NA

Alternate protein names: Fructose-biphosphate aldolase class I; FBP aldolase [H]

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MNIQNQLQATVEALVQQGKGILAMDESSPTIAKRFKPIGVESTEENRRSYRSMLLATPGLGEFVSGVILFEETLGQKADD
GTPLPALAAQQGIVPGIKVDKGKLALANAPGDEITEGLDGLALRLESYKQQGARFAKWRDVYHISATTPSRLAIEANAEV
LARYASICQTLGIVPIVEPEVLIDGDHSIDRCAEVTEAVLHEVFHALHCYHVILEHMLLKPNMVIPGKTHAQKASPEEVA
EQTIRVLRRTVPAAVPSINFLSGGLTPEEATANLNAMNCLAPQPWDLSFSYGRALQQPALQAWKGNAGNAASTQAALYLR
AKLNGAARHGSYSVTMEPAQE

Sequences:

>Translated_341_residues
MNIQNQLQATVEALVQQGKGILAMDESSPTIAKRFKPIGVESTEENRRSYRSMLLATPGLGEFVSGVILFEETLGQKADD
GTPLPALAAQQGIVPGIKVDKGKLALANAPGDEITEGLDGLALRLESYKQQGARFAKWRDVYHISATTPSRLAIEANAEV
LARYASICQTLGIVPIVEPEVLIDGDHSIDRCAEVTEAVLHEVFHALHCYHVILEHMLLKPNMVIPGKTHAQKASPEEVA
EQTIRVLRRTVPAAVPSINFLSGGLTPEEATANLNAMNCLAPQPWDLSFSYGRALQQPALQAWKGNAGNAASTQAALYLR
AKLNGAARHGSYSVTMEPAQE
>Mature_341_residues
MNIQNQLQATVEALVQQGKGILAMDESSPTIAKRFKPIGVESTEENRRSYRSMLLATPGLGEFVSGVILFEETLGQKADD
GTPLPALAAQQGIVPGIKVDKGKLALANAPGDEITEGLDGLALRLESYKQQGARFAKWRDVYHISATTPSRLAIEANAEV
LARYASICQTLGIVPIVEPEVLIDGDHSIDRCAEVTEAVLHEVFHALHCYHVILEHMLLKPNMVIPGKTHAQKASPEEVA
EQTIRVLRRTVPAAVPSINFLSGGLTPEEATANLNAMNCLAPQPWDLSFSYGRALQQPALQAWKGNAGNAASTQAALYLR
AKLNGAARHGSYSVTMEPAQE

Specific function: Unknown

COG id: COG3588

COG function: function code G; Fructose-1,6-bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class I fructose-bisphosphate aldolase family [H]

Homologues:

Organism=Homo sapiens, GI4885063, Length=326, Percent_Identity=55.8282208588957, Blast_Score=341, Evalue=5e-94,
Organism=Homo sapiens, GI34577112, Length=332, Percent_Identity=55.1204819277108, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI34577110, Length=332, Percent_Identity=55.1204819277108, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI4557305, Length=332, Percent_Identity=55.1204819277108, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI193794814, Length=332, Percent_Identity=55.1204819277108, Blast_Score=337, Evalue=1e-92,
Organism=Homo sapiens, GI40354205, Length=331, Percent_Identity=51.0574018126888, Blast_Score=322, Evalue=3e-88,
Organism=Caenorhabditis elegans, GI71983985, Length=330, Percent_Identity=52.7272727272727, Blast_Score=332, Evalue=2e-91,
Organism=Caenorhabditis elegans, GI25150450, Length=333, Percent_Identity=50.7507507507508, Blast_Score=328, Evalue=2e-90,
Organism=Caenorhabditis elegans, GI71983990, Length=236, Percent_Identity=52.5423728813559, Blast_Score=240, Evalue=9e-64,
Organism=Drosophila melanogaster, GI24650282, Length=332, Percent_Identity=55.421686746988, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24650280, Length=332, Percent_Identity=55.421686746988, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24650278, Length=332, Percent_Identity=55.421686746988, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI221459619, Length=333, Percent_Identity=55.2552552552552, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI24650288, Length=333, Percent_Identity=55.2552552552552, Blast_Score=349, Evalue=2e-96,
Organism=Drosophila melanogaster, GI45553577, Length=332, Percent_Identity=55.1204819277108, Blast_Score=345, Evalue=3e-95,
Organism=Drosophila melanogaster, GI24650304, Length=334, Percent_Identity=45.8083832335329, Blast_Score=291, Evalue=6e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000741
- InterPro:   IPR013785 [H]

Pfam domain/function: PF00274 Glycolytic [H]

EC number: =4.1.2.13 [H]

Molecular weight: Translated: 36758; Mature: 36758

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIQNQLQATVEALVQQGKGILAMDESSPTIAKRFKPIGVESTEENRRSYRSMLLATPGL
CCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCH
GEFVSGVILFEETLGQKADDGTPLPALAAQQGIVPGIKVDKGKLALANAPGDEITEGLDG
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCEECCCCEEEECCCCHHHHHHHHH
LALRLESYKQQGARFAKWRDVYHISATTPSRLAIEANAEVLARYASICQTLGIVPIVEPE
HHHHHHHHHHHCCHHHHHHHEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCC
VLIDGDHSIDRCAEVTEAVLHEVFHALHCYHVILEHMLLKPNMVIPGKTHAQKASPEEVA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
EQTIRVLRRTVPAAVPSINFLSGGLTPEEATANLNAMNCLAPQPWDLSFSYGRALQQPAL
HHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHH
QAWKGNAGNAASTQAALYLRAKLNGAARHGSYSVTMEPAQE
HHHCCCCCCCCCHHHEEEEEEECCCCCCCCCEEEEECCCCC
>Mature Secondary Structure
MNIQNQLQATVEALVQQGKGILAMDESSPTIAKRFKPIGVESTEENRRSYRSMLLATPGL
CCHHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCH
GEFVSGVILFEETLGQKADDGTPLPALAAQQGIVPGIKVDKGKLALANAPGDEITEGLDG
HHHHHHHHHHHHHHCCCCCCCCCCCHHHHHCCCCCCCEECCCCEEEECCCCHHHHHHHHH
LALRLESYKQQGARFAKWRDVYHISATTPSRLAIEANAEVLARYASICQTLGIVPIVEPE
HHHHHHHHHHHCCHHHHHHHEEEEECCCCCEEEEECCHHHHHHHHHHHHHHCCCEECCCC
VLIDGDHSIDRCAEVTEAVLHEVFHALHCYHVILEHMLLKPNMVIPGKTHAQKASPEEVA
EEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCHHHHH
EQTIRVLRRTVPAAVPSINFLSGGLTPEEATANLNAMNCLAPQPWDLSFSYGRALQQPAL
HHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHCCCCHHHCCCCCCCCCCCHHHHHHHHHHH
QAWKGNAGNAASTQAALYLRAKLNGAARHGSYSVTMEPAQE
HHHCCCCCCCCCHHHEEEEEEECCCCCCCCCEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]