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The map label for this gene is prmA

Identifier: 114331873

GI number: 114331873

Start: 2013617

End: 2014558

Strand: Reverse

Name: prmA

Synonym: Neut_1898

Alternate gene names: 114331873

Gene position: 2014558-2013617 (Counterclockwise)

Preceding gene: 114331874

Following gene: 114331872

Centisome position: 75.71

GC content: 50.42

Gene sequence:

>942_bases
ATGTCCTGGCTCTCTCTGACTTTTAAAGTTGGGTCCGATTACGTTGATTCGGTAAGTGATCAGTTGCTGGAGCAGGGCGC
ACTGTCAGTTGATGTACATGATGCGGGTGAAGGGACTGATCACGAACAACCCTTGTTTGGTGAACCAGGTGCTCTCCCGG
AGCAATTCTGGCAACAGGCAGAGGTAACAGTATTGCTCGAGGAAAATACGGATGTTGATGAAATTGTGCAGGCAGTAGCT
CGGGTGATGGGGATATCTGCGCTGCCAGACTATCAATTGACGCAAGTAGTGGAACAGGATTGGGTCAGATTGACACAGGC
GCAATTCGAGCCAATCAAAATTTCCTCGCGATTGTGGGTCGTTCCATCTTGGCATGATTTACCCGATCCTGCAGCAATTA
ATCTGCGACTGGATCCGGGACTGGCTTTTGGTACGGGCAGTCATCCGACCACACAGTTGTGCCTGGGCTGGCTGGATAAA
TTTCTTAAACCTGGCGACAGCGTGCTTGATTATGGCTGTGGCTCCGGGATTCTGGCAATCGCAGCGTTAAAACTGGGGGC
TGACCGGGTGATGGGCGTGGATATTGATCCGAATGCCATTACTGCCAGCCTCGAAAATGCCCGGAACAATCTCTGTGATC
TGGATAAATTATCATTTACCACTGCGCTATCCTTTTCTGGAGGTGGCGATCCTGCTGATACCAGGCAGCATCCTGTTTTC
GTAGTGGTCGCGAACATTCTGGCTAATCCTCTGATCATGCTGGCCCCTGTTCTGATGAGTGCCTTGCAACCAGGCGGACG
TATCGTGCTTTCAGGAATACTGGAAACCCAGGCTGATGAAGTGCTGCAGATTTACAGCGAGTGGTTTGATATGCAGATTG
CTGCAAAAGATCAGGGATGGGTACTGCTTGCAGGTCGGAAATCAGTCAATAGGACATCATGA

Upstream 100 bases:

>100_bases
CCGATTCTGTCTCTATTCACTATCTTGAAAACAAGCTTGCACTGTATAACAAAAAAACGACTTGATGTGATCGTGATAAA
ACCTGTTACACAGATCAGCT

Downstream 100 bases:

>100_bases
CACTGGTGACACGCTGTCCTGGCTGTCATGCGATTTTTCGCCTGACGGGTGGGCAGCTGCATTCGCATAACGGTGATGTG
CGCTGCGGGCAGTGTAAGCA

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MSWLSLTFKVGSDYVDSVSDQLLEQGALSVDVHDAGEGTDHEQPLFGEPGALPEQFWQQAEVTVLLEENTDVDEIVQAVA
RVMGISALPDYQLTQVVEQDWVRLTQAQFEPIKISSRLWVVPSWHDLPDPAAINLRLDPGLAFGTGSHPTTQLCLGWLDK
FLKPGDSVLDYGCGSGILAIAALKLGADRVMGVDIDPNAITASLENARNNLCDLDKLSFTTALSFSGGGDPADTRQHPVF
VVVANILANPLIMLAPVLMSALQPGGRIVLSGILETQADEVLQIYSEWFDMQIAAKDQGWVLLAGRKSVNRTS

Sequences:

>Translated_313_residues
MSWLSLTFKVGSDYVDSVSDQLLEQGALSVDVHDAGEGTDHEQPLFGEPGALPEQFWQQAEVTVLLEENTDVDEIVQAVA
RVMGISALPDYQLTQVVEQDWVRLTQAQFEPIKISSRLWVVPSWHDLPDPAAINLRLDPGLAFGTGSHPTTQLCLGWLDK
FLKPGDSVLDYGCGSGILAIAALKLGADRVMGVDIDPNAITASLENARNNLCDLDKLSFTTALSFSGGGDPADTRQHPVF
VVVANILANPLIMLAPVLMSALQPGGRIVLSGILETQADEVLQIYSEWFDMQIAAKDQGWVLLAGRKSVNRTS
>Mature_312_residues
SWLSLTFKVGSDYVDSVSDQLLEQGALSVDVHDAGEGTDHEQPLFGEPGALPEQFWQQAEVTVLLEENTDVDEIVQAVAR
VMGISALPDYQLTQVVEQDWVRLTQAQFEPIKISSRLWVVPSWHDLPDPAAINLRLDPGLAFGTGSHPTTQLCLGWLDKF
LKPGDSVLDYGCGSGILAIAALKLGADRVMGVDIDPNAITASLENARNNLCDLDKLSFTTALSFSGGGDPADTRQHPVFV
VVANILANPLIMLAPVLMSALQPGGRIVLSGILETQADEVLQIYSEWFDMQIAAKDQGWVLLAGRKSVNRTS

Specific function: Methylates ribosomal protein L11

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family

Homologues:

Organism=Escherichia coli, GI2367208, Length=310, Percent_Identity=40.3225806451613, Blast_Score=188, Evalue=5e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PRMA_NITEC (Q0AEV2)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_748095.1
- ProteinModelPortal:   Q0AEV2
- SMR:   Q0AEV2
- STRING:   Q0AEV2
- GeneID:   4274144
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_1898
- NMPDR:   fig|335283.3.peg.1023
- eggNOG:   COG2264
- HOGENOM:   HBG584653
- OMA:   EREEWCR
- PhylomeDB:   Q0AEV2
- ProtClustDB:   PRK00517
- BioCyc:   NEUT335283:NEUT_1898-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00735
- InterPro:   IPR010456
- InterPro:   IPR004498
- TIGRFAMs:   TIGR00406

Pfam domain/function: PF06325 PrmA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 33892; Mature: 33761

Theoretical pI: Translated: 4.09; Mature: 4.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSWLSLTFKVGSDYVDSVSDQLLEQGALSVDVHDAGEGTDHEQPLFGEPGALPEQFWQQA
CCCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCC
EVTVLLEENTDVDEIVQAVARVMGISALPDYQLTQVVEQDWVRLTQAQFEPIKISSRLWV
CEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEE
VPSWHDLPDPAAINLRLDPGLAFGTGSHPTTQLCLGWLDKFLKPGDSVLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHH
AALKLGADRVMGVDIDPNAITASLENARNNLCDLDKLSFTTALSFSGGGDPADTRQHPVF
HHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCCCEE
VVVANILANPLIMLAPVLMSALQPGGRIVLSGILETQADEVLQIYSEWFDMQIAAKDQGW
EEEHHHHHCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCE
VLLAGRKSVNRTS
EEEECCCCCCCCC
>Mature Secondary Structure 
SWLSLTFKVGSDYVDSVSDQLLEQGALSVDVHDAGEGTDHEQPLFGEPGALPEQFWQQA
CCEEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCCHHHHHCCC
EVTVLLEENTDVDEIVQAVARVMGISALPDYQLTQVVEQDWVRLTQAQFEPIKISSRLWV
CEEEEEECCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEECCEEEE
VPSWHDLPDPAAINLRLDPGLAFGTGSHPTTQLCLGWLDKFLKPGDSVLDYGCGSGILAI
EECCCCCCCCCEEEEEECCCEEECCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCHHHHH
AALKLGADRVMGVDIDPNAITASLENARNNLCDLDKLSFTTALSFSGGGDPADTRQHPVF
HHHHHCCCCEEEECCCCCHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCCCCCCCCEE
VVVANILANPLIMLAPVLMSALQPGGRIVLSGILETQADEVLQIYSEWFDMQIAAKDQGW
EEEHHHHHCHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHHHHHHHHHCEEEEECCCCE
VLLAGRKSVNRTS
EEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA