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The map label for this gene is insF1 [C]

Identifier: 114331795

GI number: 114331795

Start: 1927409

End: 1928200

Strand: Reverse

Name: insF1 [C]

Synonym: Neut_1819

Alternate gene names: 114331795

Gene position: 1928200-1927409 (Counterclockwise)

Preceding gene: 114331796

Following gene: 114331794

Centisome position: 72.46

GC content: 57.83

Gene sequence:

>792_bases
TTGCGCAGTGCTCGCGTCCTGCGTGATGATGAACTGCTGCCGCAAATACAGCGGGTCTGGCAGACCAACATGCAGGTCTA
TGGTGCCGACAAGGTCTGGCGTCAGCTTAAGCGTGAAGATGTCCAGGTGGCACGCTGTACGGTCGAACGGCTCATGAAAC
GGTTAGGGCTGAAAGGCGCCAGGCGTGGCAAGGTTGTGCGCACCACAGTTCCGGACAAGGCGCTGCCGTGTCCACTGGAT
CGGGTTAACCGGCAATTCAAGGCAGATCGTCCGAACCAGTTGTGGGTGTCAGACTTCACCTATGTCTCGACCTGGCAAGG
CTGGCTGTATGTGGCTTTCGTCATCGATGTATTTGCCCGGCGCATTGTGGGCTGGCAGGTGAGCAGCTCCATGCGCACGG
ACTTTGTGCTGGATGCCCTGGAACAAGCGCTGTATGCCCGGCAACCGGGGCGGATGGATGCCTTGGTACACCATAGCGAC
AGAGGCTCGCAATATGTCTCCATTCGCTATACCGAGCGACTCGCCGAAGCCGGAATAAAACCCTCGGTCGGCAGCAAGGG
CGACAGCTACGACAACGCGCTGGCAGAAACCATCAATGGGCTGTACAAAACAGAATTGATTCACAAGCGCGCCCCCTGGA
AAACCAGGGAGGCCGTGGAGCTGGCAACGCTGGAATGGGTAGCCTGGTTCAACAACCAGCGGCTGCTGGAACCAATCGGT
TACATCCCTCCCGCAGAAGCTGAGGTAAACTACTATAGGCAATTCGCCAGGGAAGCCATTCCGGTGGCTTGA

Upstream 100 bases:

>100_bases
CCAGCACCGCGACGCCCATGGGGTCGAGCCGATCTGCAAGGTTTTGCAGGTCGCCCCATCAGGGTATCGGCGATATTTCG
CGCAGCAGCGTAATCCGGCT

Downstream 100 bases:

>100_bases
CTTTAACCAAACAGCCTCCTCAAAACCCGGGACGATTCATCAAGAGAGTCTGAATGTTCTGGCCAAGCGGCATGGGATTA
ATCCAAAAACGGTAGCGAAG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 263; Mature: 263

Protein sequence:

>263_residues
MRSARVLRDDELLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGARRGKVVRTTVPDKALPCPLD
RVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSD
RGSQYVSIRYTERLAEAGIKPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVELATLEWVAWFNNQRLLEPIG
YIPPAEAEVNYYRQFAREAIPVA

Sequences:

>Translated_263_residues
MRSARVLRDDELLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGARRGKVVRTTVPDKALPCPLD
RVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSD
RGSQYVSIRYTERLAEAGIKPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVELATLEWVAWFNNQRLLEPIG
YIPPAEAEVNYYRQFAREAIPVA
>Mature_263_residues
MRSARVLRDDELLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGARRGKVVRTTVPDKALPCPLD
RVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFARRIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSD
RGSQYVSIRYTERLAEAGIKPSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVELATLEWVAWFNNQRLLEPIG
YIPPAEAEVNYYRQFAREAIPVA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=220, Percent_Identity=56.3636363636364, Blast_Score=238, Evalue=3e-63,
Organism=Escherichia coli, GI1788405, Length=225, Percent_Identity=31.5555555555556, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1787263, Length=225, Percent_Identity=31.5555555555556, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786753, Length=225, Percent_Identity=31.5555555555556, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786570, Length=225, Percent_Identity=31.5555555555556, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786490, Length=225, Percent_Identity=31.5555555555556, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1789981, Length=233, Percent_Identity=32.1888412017167, Blast_Score=110, Evalue=7e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 30456; Mature: 30456

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSARVLRDDELLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGA
CCCCCCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRGKVVRTTVPDKALPCPLDRVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFAR
CCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
RIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSDRGSQYVSIRYTERLAEAGIK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEEHHHHHHHHCCCC
PSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVELATLEWVAWFNNQRLLEPIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHC
YIPPAEAEVNYYRQFAREAIPVA
CCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRSARVLRDDELLPQIQRVWQTNMQVYGADKVWRQLKREDVQVARCTVERLMKRLGLKGA
CCCCCCCCCHHHHHHHHHHHHHCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RRGKVVRTTVPDKALPCPLDRVNRQFKADRPNQLWVSDFTYVSTWQGWLYVAFVIDVFAR
CCCCEEEECCCCCCCCCCHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHH
RIVGWQVSSSMRTDFVLDALEQALYARQPGRMDALVHHSDRGSQYVSIRYTERLAEAGIK
HHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHEEECCCCCEEEEEHHHHHHHHCCCC
PSVGSKGDSYDNALAETINGLYKTELIHKRAPWKTREAVELATLEWVAWFNNQRLLEPIG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHC
YIPPAEAEVNYYRQFAREAIPVA
CCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2159625; 2824781 [H]