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The map label for this gene is insF1 [H]

Identifier: 114331791

GI number: 114331791

Start: 1924065

End: 1924892

Strand: Direct

Name: insF1 [H]

Synonym: Neut_1814

Alternate gene names: 114331791

Gene position: 1924065-1924892 (Clockwise)

Preceding gene: 114331790

Following gene: 114331805

Centisome position: 72.3

GC content: 45.77

Gene sequence:

>828_bases
ATGTGCCGACTCATGGGTGTAAGCCGCAGTGCCTACTATGATTACGTTCGTTGTGCTGACAATTGTTCTACCGACCCGTG
CCATATAGAAATACTTGGAGCAGTACGGGAGATAGCAAAATCCAGTCATCATAGCTATGGCAGTCGCAGAATCGGAAAAG
CGCTGAATGCACGGGGTTATCCGGTTGGTCGCAGGAAGGCTCGAAGCCTGATGCGAGAAGCAGATGTGCAAGTGAGGCAC
CGGAAAAAGTACAAGGTCACAACTAACAGTAATCACAAACAACCGATATTTGAGAATAGGCTGAATCGGCAATTTGATGT
TGCAGCCCCCAATCAAATCTACGTTGGTGACATTACCTGCATTTGGACCCGGGAAGGCTGGTTGTATCTGGCGGTGGTCA
TTGATTTGTTTTCCAGGAAGGTGGTGGGTTGGAGCATGAGTTCAAGAATGAAAGCAAAGCTGGTTTGTGATGCATTGAGA
ATGGCTGTCTGGCAGCGTCAACCACAACCTGGATTGATTGTACATTCAGATCGTGGATCGCAATATGCCAGCAAGCAGTA
CCGCCAACTTTTAAAAATACACGGCTTTATCGGCAGTATGAGTCGTAGGGGAAATTGTTGGGATAATTCAGTGGCTGAAA
GCTTTTTCGGTAGCCTTAAACGGGAGCAAATCCACTGGCAACATTATCCAACCCGCCATAAAGCACAACAAGATGTACTG
CAGTATATTTCCATGTTCTATAACAGCCAGCGACTGCATTCATACCTGGGTTACAAAAACCCGAATCAATATGAGATGGA
AATGGAAATAGTGAAAAATGTTGCTTAA

Upstream 100 bases:

>100_bases
AGAAGCGCATCTTAAAGGAAGCGACGGTCTTTTTTGCGAAAGAAACGAAGTGAAATATTCGTTTATCACCCAAAGGAAAA
AGACCTATCCGGTCGGCTTG

Downstream 100 bases:

>100_bases
CTGGAGTGTCCGGTTTTACTTGACCAGGTCAGTAATGCTGCCGTTTAAGCTCTGAAAATAGGATATATTTCATGAGTTAC
CGTTAATTTTATAGCCTGTG

Product: integrase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MCRLMGVSRSAYYDYVRCADNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMREADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYLGYKNPNQYEMEMEIVKNVA

Sequences:

>Translated_275_residues
MCRLMGVSRSAYYDYVRCADNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMREADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYLGYKNPNQYEMEMEIVKNVA
>Mature_275_residues
MCRLMGVSRSAYYDYVRCADNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGYPVGRRKARSLMREADVQVRH
RKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITCIWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALR
MAVWQRQPQPGLIVHSDRGSQYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
QYISMFYNSQRLHSYLGYKNPNQYEMEMEIVKNVA

Specific function: Involved in the transposition of the insertion sequence IS3 [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=233, Percent_Identity=35.6223175965665, Blast_Score=140, Evalue=1e-33,
Organism=Escherichia coli, GI1788405, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1787263, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1786753, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1786570, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1786490, Length=270, Percent_Identity=42.2222222222222, Blast_Score=212, Evalue=2e-56,
Organism=Escherichia coli, GI1789981, Length=268, Percent_Identity=30.2238805970149, Blast_Score=127, Evalue=7e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32075; Mature: 32075

Theoretical pI: Translated: 10.32; Mature: 10.32

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCRLMGVSRSAYYDYVRCADNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGY
CCCEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVGRRKARSLMREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITC
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEE
IWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAVWQRQPQPGLIVHSDRGS
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QYISMFYNSQRLHSYLGYKNPNQYEMEMEIVKNVA
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MCRLMGVSRSAYYDYVRCADNCSTDPCHIEILGAVREIAKSSHHSYGSRRIGKALNARGY
CCCEECCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCC
PVGRRKARSLMREADVQVRHRKKYKVTTNSNHKQPIFENRLNRQFDVAAPNQIYVGDITC
CCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCHHHHHCCCEEECCCCCEEEEEEEEE
IWTREGWLYLAVVIDLFSRKVVGWSMSSRMKAKLVCDALRMAVWQRQPQPGLIVHSDRGS
EEECCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCC
QYASKQYRQLLKIHGFIGSMSRRGNCWDNSVAESFFGSLKREQIHWQHYPTRHKAQQDVL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
QYISMFYNSQRLHSYLGYKNPNQYEMEMEIVKNVA
HHHHHHHCHHHHHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2987844; 9278503 [H]