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The map label for this gene is rpiA [H]

Identifier: 114331805

GI number: 114331805

Start: 1937439

End: 1938164

Strand: Direct

Name: rpiA [H]

Synonym: Neut_1829

Alternate gene names: 114331805

Gene position: 1937439-1938164 (Clockwise)

Preceding gene: 114331791

Following gene: 114331806

Centisome position: 72.81

GC content: 48.76

Gene sequence:

>726_bases
ATGCGCAAGCGCTCTGAATCCTTCTCAATGAGAGCACTATTTCAAGAACCAATTATTAAAATCATCATGACACAAGACGA
ACAAAAACAGGCAGTGGCACAAGCAGCCCTGCAGTATGTGCAGGTAGGTGAAATCATCGGTATCGGAACAGGGTCGACCA
CCAATCTTTTTATTGATGAACTGGCCAAAATCAAACACAAGATTGAAGGGGCCGTGGCAAGCTCCGAAGCAACCGCAGCC
CGTCTGAAGCAACATGGCATTGAGGTTTTGAGCCTCAATTCTGTTGCTGACCTCCCGGTATATATTGATGGCGCAGATGA
AATTACCCGGAACATGCACATGATCAAAGGTGGTGGCGGCGCACTGACACGTGAAAAAATCATTGCAGCCGTCGCTCGGA
AGTTTATCTGTATTGCTGATCAAAGCAAGCTGGTCAAGGTATTGGGAAAATTTCCGCTCCCGGTGGAGGTGATTCCGATG
GCACGCAGTTATGTCGCCCGGGAAATTGCATTACTGGGCGGACAACCAGCCTGGCGTCAGGATTTCACCACTGACAATGG
CAATGTGATTCTCGACATACATAATCTAAATATCATGAATCCGGTTGAACTGGAAAGCACGCTCAACCAGATCACAGGGG
TGGTGACCAACGGCCTGTTTGCCAGACGAGGCGCTGATGTACTGTTGATGGGTACTGATCAGGGCGTGGAAACCATTACG
ATCTAG

Upstream 100 bases:

>100_bases
AAACCGGGGCTGGAATAGAATAAATATGCGGAAAAACTCACTGAATCGGTAATTATACTGTCACCAAGTTATGATACGCT
TGCTGTCAAACAGGGGAAGG

Downstream 100 bases:

>100_bases
GAACTTGTTCAATATCTCGCTGAAAGGCGCATTACGGCGTTGAAATTGAACTCAAAATGCTCACATACTTCAAGTATGCT
CCGCTTTCTCGTTCAATTTT

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MRKRSESFSMRALFQEPIIKIIMTQDEQKQAVAQAALQYVQVGEIIGIGTGSTTNLFIDELAKIKHKIEGAVASSEATAA
RLKQHGIEVLSLNSVADLPVYIDGADEITRNMHMIKGGGGALTREKIIAAVARKFICIADQSKLVKVLGKFPLPVEVIPM
ARSYVAREIALLGGQPAWRQDFTTDNGNVILDIHNLNIMNPVELESTLNQITGVVTNGLFARRGADVLLMGTDQGVETIT
I

Sequences:

>Translated_241_residues
MRKRSESFSMRALFQEPIIKIIMTQDEQKQAVAQAALQYVQVGEIIGIGTGSTTNLFIDELAKIKHKIEGAVASSEATAA
RLKQHGIEVLSLNSVADLPVYIDGADEITRNMHMIKGGGGALTREKIIAAVARKFICIADQSKLVKVLGKFPLPVEVIPM
ARSYVAREIALLGGQPAWRQDFTTDNGNVILDIHNLNIMNPVELESTLNQITGVVTNGLFARRGADVLLMGTDQGVETIT
I
>Mature_241_residues
MRKRSESFSMRALFQEPIIKIIMTQDEQKQAVAQAALQYVQVGEIIGIGTGSTTNLFIDELAKIKHKIEGAVASSEATAA
RLKQHGIEVLSLNSVADLPVYIDGADEITRNMHMIKGGGGALTREKIIAAVARKFICIADQSKLVKVLGKFPLPVEVIPM
ARSYVAREIALLGGQPAWRQDFTTDNGNVILDIHNLNIMNPVELESTLNQITGVVTNGLFARRGADVLLMGTDQGVETIT
I

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=218, Percent_Identity=34.8623853211009, Blast_Score=105, Evalue=5e-23,
Organism=Escherichia coli, GI1789280, Length=217, Percent_Identity=64.5161290322581, Blast_Score=283, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17551758, Length=241, Percent_Identity=33.195020746888, Blast_Score=102, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=238, Percent_Identity=28.5714285714286, Blast_Score=81, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281364072, Length=196, Percent_Identity=35.7142857142857, Blast_Score=90, Evalue=2e-18,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF00455 DeoR; PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 26179; Mature: 26179

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKRSESFSMRALFQEPIIKIIMTQDEQKQAVAQAALQYVQVGEIIGIGTGSTTNLFIDE
CCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHH
LAKIKHKIEGAVASSEATAARLKQHGIEVLSLNSVADLPVYIDGADEITRNMHMIKGGGG
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCEEECCHHHHHHCEEEEECCCC
ALTREKIIAAVARKFICIADQSKLVKVLGKFPLPVEVIPMARSYVAREIALLGGQPAWRQ
CHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCC
DFTTDNGNVILDIHNLNIMNPVELESTLNQITGVVTNGLFARRGADVLLMGTDQGVETIT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCEEEE
I
C
>Mature Secondary Structure
MRKRSESFSMRALFQEPIIKIIMTQDEQKQAVAQAALQYVQVGEIIGIGTGSTTNLFIDE
CCCCCCHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHCCEEEECCCCCHHHHHHH
LAKIKHKIEGAVASSEATAARLKQHGIEVLSLNSVADLPVYIDGADEITRNMHMIKGGGG
HHHHHHHHHHHHCCCHHHHHHHHHCCCEEEEECCCCCCCEEECCHHHHHHCEEEEECCCC
ALTREKIIAAVARKFICIADQSKLVKVLGKFPLPVEVIPMARSYVAREIALLGGQPAWRQ
CHHHHHHHHHHHHHHEEECCHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCCC
DFTTDNGNVILDIHNLNIMNPVELESTLNQITGVVTNGLFARRGADVLLMGTDQGVETIT
CCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHCCHHHHCCCCEEEEECCCCCEEEE
I
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]