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The map label for this gene is dhaK [H]

Identifier: 114331368

GI number: 114331368

Start: 1444338

End: 1445954

Strand: Direct

Name: dhaK [H]

Synonym: Neut_1377

Alternate gene names: 114331368

Gene position: 1444338-1445954 (Clockwise)

Preceding gene: 114331367

Following gene: 114331371

Centisome position: 54.28

GC content: 61.16

Gene sequence:

>1617_bases
ATGGCCCAGTTCATCAACAGCAAAGAAAGCATCGTCACCGAAGCCGTCGATGGCCTGATCGCGGCGTCTGGCGGTAAGCT
GGCGCGGCTCGACGGCTATCCGCATATACGGGTGGTTGTACGCAATGACTGGGACAAGTCCAAGGTCGCGTTGATTTCGG
GAGGTGGATCAGGCCACGAACCGGCACATGCGGGTTTCGTCGGGGAAGGGATGCTGACGGCTGCGGTGTGCGGCGACATC
TTCGCCTCGCCGACAGTCGATGCAGTACTGGCAGGCATCCTTGCCGTGACAGGATCGTCCGGTTGCCTGCTCATCGTCAA
GAATTATACCGGTGACCGATTGAATTTCGGGCTGGCGGCTGAGCGCGCTCGCCAGTTTGGCTTGATTGTCGAGATAGTTA
TCGTCGACGATGATGTGGCGTTGCCAGGCTTGCCCCAAGCCCGCGGCGTTGCTGGCACGCTTTTTGTCCACAAGATAGCC
GGCGCGTTGGCCGAAAATGGTGCCGACTTGGCGCACGTCGCCGCGGCCGCACGCAAGGTTGTGTCAAAGACAAAAAGTAT
TGGCATGTCGCTCAGCACCTGCACCATCCCAGGTTCACCAAAGGAAGATCGCATCCCGCCCGGCATGGCCGAGCTTGGGC
TTGGCATTCACGGTGAAGCCGGAGTTGAGCAGGTCGAGTTCAAGGGCGCGAGCGAAGCTGTCGCTGCCATGGTCGAGCAC
CTGTCAGTTGCAATGGAAGAAAAGCCGCATGTCGCTATGGTCAACAATCTCGGCGGCACGTCGATCATCGAGATGTCGAT
CATCCTCAACGAAATCCAGCGGTCAGCGATTGGCGAGCGGATAACCCACGTCATCGGGCCGGCGGCCATGATGACATCTC
TCGACATGCACGGCTTTTCGATTTCGGTCTATCCTGCCGACGATACCGAGATCGCCCTGCTCAAGCAGCACACGCCGCTG
GCAGCATGGCCGCGGGTCTCCCGGCTGGGCCAGGTCGCTATTCAGGCGCTTCCGGACGGCCTGACGCCTGTCGTTCCGAT
GCCCTCGCAGCACAAGCCGACCAGGGAGTTCCTGACCAGATGCTGCGAGGTTCTGATCGCCGCTGAGAACGACCTCAACG
CGCTCGACGCGAAGTCAGGCGATGGCGACACCGGAAGCACGCTAGCCGGCGCGGCACGCGCCCTGATCAGCGCCATGGAC
CGATTGCCGCTTGCCGACCATACCCAACTCTATCGCGCTATTGGCTTGGAGCTTTCCAAAACCATGGGAGGCTCGTTCGG
TGTGCTCCTCGCGATCTTCTTCGCCGCAACGGGCGACGCCGCGTCAAGCGGCTTGCCAATGTACGAAGCGTTGCAGGCCG
GACTGCGGAGAATGCAGGAGATCGGCGGGGCACGTCCGGGTGACCGCACCATGGTCGATGCCCTTGCGCCGGCTCTTGAT
GCCCTGGAAGAGAGCCTGTCCGAAGCGGCGAAAGCCGCGCGTGCAGGTGCCGATCGCACTGCCCACATGAGTGTGGCGAA
TGTTGGTCGCGCTTCCTATGTCAATGCCAAGCATTTGGTCGGTCACGCTGATCCAGGTGCTGAGGCGGTCGCGCGACTGT
TTGAACACTTGGCCTAA

Upstream 100 bases:

>100_bases
ACCGTGGGACTAAACATCCTAAGACCCTTAACTAAATATCTTTTAATAACTTTTAAATTCATTTTTATCACAAATTATTT
TTTGCAACAGATCTGAAAAC

Downstream 100 bases:

>100_bases
TTTTAGATAGTAAGCATCTATTTAAAACATGTAATGAAACTACGTCACTATCAGATCCGCTGTCAGACGAATGAGATTGT
TAACGTCCCAGGCCAAAATC

Product: Glycerone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 538; Mature: 537

Protein sequence:

>538_residues
MAQFINSKESIVTEAVDGLIAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPAHAGFVGEGMLTAAVCGDI
FASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARQFGLIVEIVIVDDDVALPGLPQARGVAGTLFVHKIA
GALAENGADLAHVAAAARKVVSKTKSIGMSLSTCTIPGSPKEDRIPPGMAELGLGIHGEAGVEQVEFKGASEAVAAMVEH
LSVAMEEKPHVAMVNNLGGTSIIEMSIILNEIQRSAIGERITHVIGPAAMMTSLDMHGFSISVYPADDTEIALLKQHTPL
AAWPRVSRLGQVAIQALPDGLTPVVPMPSQHKPTREFLTRCCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAMD
RLPLADHTQLYRAIGLELSKTMGGSFGVLLAIFFAATGDAASSGLPMYEALQAGLRRMQEIGGARPGDRTMVDALAPALD
ALEESLSEAAKAARAGADRTAHMSVANVGRASYVNAKHLVGHADPGAEAVARLFEHLA

Sequences:

>Translated_538_residues
MAQFINSKESIVTEAVDGLIAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPAHAGFVGEGMLTAAVCGDI
FASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARQFGLIVEIVIVDDDVALPGLPQARGVAGTLFVHKIA
GALAENGADLAHVAAAARKVVSKTKSIGMSLSTCTIPGSPKEDRIPPGMAELGLGIHGEAGVEQVEFKGASEAVAAMVEH
LSVAMEEKPHVAMVNNLGGTSIIEMSIILNEIQRSAIGERITHVIGPAAMMTSLDMHGFSISVYPADDTEIALLKQHTPL
AAWPRVSRLGQVAIQALPDGLTPVVPMPSQHKPTREFLTRCCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAMD
RLPLADHTQLYRAIGLELSKTMGGSFGVLLAIFFAATGDAASSGLPMYEALQAGLRRMQEIGGARPGDRTMVDALAPALD
ALEESLSEAAKAARAGADRTAHMSVANVGRASYVNAKHLVGHADPGAEAVARLFEHLA
>Mature_537_residues
AQFINSKESIVTEAVDGLIAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHEPAHAGFVGEGMLTAAVCGDIF
ASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAAERARQFGLIVEIVIVDDDVALPGLPQARGVAGTLFVHKIAG
ALAENGADLAHVAAAARKVVSKTKSIGMSLSTCTIPGSPKEDRIPPGMAELGLGIHGEAGVEQVEFKGASEAVAAMVEHL
SVAMEEKPHVAMVNNLGGTSIIEMSIILNEIQRSAIGERITHVIGPAAMMTSLDMHGFSISVYPADDTEIALLKQHTPLA
AWPRVSRLGQVAIQALPDGLTPVVPMPSQHKPTREFLTRCCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAMDR
LPLADHTQLYRAIGLELSKTMGGSFGVLLAIFFAATGDAASSGLPMYEALQAGLRRMQEIGGARPGDRTMVDALAPALDA
LEESLSEAAKAARAGADRTAHMSVANVGRASYVNAKHLVGHADPGAEAVARLFEHLA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=566, Percent_Identity=40.4593639575972, Blast_Score=329, Evalue=4e-90,
Organism=Escherichia coli, GI87081857, Length=362, Percent_Identity=36.4640883977901, Blast_Score=189, Evalue=3e-49,
Organism=Escherichia coli, GI1787449, Length=200, Percent_Identity=31, Blast_Score=71, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17565018, Length=568, Percent_Identity=36.0915492957746, Blast_Score=287, Evalue=1e-77,
Organism=Saccharomyces cerevisiae, GI6321055, Length=594, Percent_Identity=34.8484848484849, Blast_Score=240, Evalue=3e-64,
Organism=Saccharomyces cerevisiae, GI6323570, Length=557, Percent_Identity=33.3931777378815, Blast_Score=233, Evalue=4e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 55745; Mature: 55613

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQFINSKESIVTEAVDGLIAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHE
CCCCCCCHHHHHHHHHHHHEECCCCCEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCC
PAHAGFVGEGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAA
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARQFGLIVEIVIVDDDVALPGLPQARGVAGTLFVHKIAGALAENGADLAHVAAAARKV
HHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VSKTKSIGMSLSTCTIPGSPKEDRIPPGMAELGLGIHGEAGVEQVEFKGASEAVAAMVEH
HHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHH
LSVAMEEKPHVAMVNNLGGTSIIEMSIILNEIQRSAIGERITHVIGPAAMMTSLDMHGFS
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ISVYPADDTEIALLKQHTPLAAWPRVSRLGQVAIQALPDGLTPVVPMPSQHKPTREFLTR
EEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
CCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAMDRLPLADHTQLYRAIGLELSK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
TMGGSFGVLLAIFFAATGDAASSGLPMYEALQAGLRRMQEIGGARPGDRTMVDALAPALD
HCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALEESLSEAAKAARAGADRTAHMSVANVGRASYVNAKHLVGHADPGAEAVARLFEHLA
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure 
AQFINSKESIVTEAVDGLIAASGGKLARLDGYPHIRVVVRNDWDKSKVALISGGGSGHE
CCCCCCHHHHHHHHHHHHEECCCCCEEEECCCCEEEEEEECCCCCCEEEEEECCCCCCC
PAHAGFVGEGMLTAAVCGDIFASPTVDAVLAGILAVTGSSGCLLIVKNYTGDRLNFGLAA
CCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARQFGLIVEIVIVDDDVALPGLPQARGVAGTLFVHKIAGALAENGADLAHVAAAARKV
HHHHHCCEEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
VSKTKSIGMSLSTCTIPGSPKEDRIPPGMAELGLGIHGEAGVEQVEFKGASEAVAAMVEH
HHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCHHHHHHHHHHH
LSVAMEEKPHVAMVNNLGGTSIIEMSIILNEIQRSAIGERITHVIGPAAMMTSLDMHGFS
HHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
ISVYPADDTEIALLKQHTPLAAWPRVSRLGQVAIQALPDGLTPVVPMPSQHKPTREFLTR
EEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
CCEVLIAAENDLNALDAKSGDGDTGSTLAGAARALISAMDRLPLADHTQLYRAIGLELSK
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHH
TMGGSFGVLLAIFFAATGDAASSGLPMYEALQAGLRRMQEIGGARPGDRTMVDALAPALD
HCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALEESLSEAAKAARAGADRTAHMSVANVGRASYVNAKHLVGHADPGAEAVARLFEHLA
HHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCHHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA