Click here to switch to the map view.

The map label for this gene is macB [H]

Identifier: 114331337

GI number: 114331337

Start: 1411233

End: 1412432

Strand: Direct

Name: macB [H]

Synonym: Neut_1344

Alternate gene names: 114331337

Gene position: 1411233-1412432 (Clockwise)

Preceding gene: 114331336

Following gene: 114331339

Centisome position: 53.03

GC content: 53.5

Gene sequence:

>1200_bases
ATGAATCTTGTTGAATCCCTGAGATTTGCACTCCGCGCATTAACCGCCCACCGAACGCGCACATTTCTGTCTGCATCCGG
TATTGCCATCGGCATTGCCGCCGTGATCCTGTTAACATCAATCGGTGCAGGTATCCAGCGTTTTGTGTTATCCGAATTCA
CCCAGTTTGGAACCAACATTGTGAATATCACACCCGGCAAGACTCGTACGCGAGGTGCTTCGACCGGATCAATTAGCAGT
GTGCGCCTGTTGACAATTGAGGATTCGCTCGCGCTGAAATCCTCTCGCCATGCGGTCTATACCAATGCAACCGTCACCGG
GAACGCGGAAGTACGCGGTAACGGCCACAGCCGACGAGTTACTGTATATGGCCAGGGGCCGGATTTCGATCGGGCATTTA
ATATGCACACTGCGATCGGGCAATTCCTACCAGCGGACGATCCGCGTAATCCACGCGCCTTTGCTGTGCTCGGTGCAAAA
GTACACAAGGAGCTGTACGGCAGTACCAATCCGCTTGGCTCGGTACTGCAGGTCGGTGGTTCACGTTTTCGTATCATTGG
TGTCATGGCCTCCAAGGGCCAGGTACTGGGTTTTGATCTGGATGATACGGTTTACATTCCCACAGCACGGGCATTGGAAG
TTTTCAACCGGGAAGGTGTGATGGAAATTCAGGTAGTCTATCCGCCAGCCACACCACTGGATGAAGTCACGCAAGATATC
AAACGTATCATGCTTAAACGGCACGGGCGTGAAGATTTTACGATAACACCACAGCAGCAGATGCTCAGTACACTCTCTAC
CGTACTGAATGTACTGACTTTTGCCGTCGCGGTATTGGGAGGAATTTCATTGCTGGTCGGAGCGGTGGGGATGATCACAC
TGATGCACATCACTGTAACAGAACGGATGGCCGAGATCGGCTTGCTGAATGCATTAGGTGCAACCCCCATGCGTATCCGT
ATCTTGTTCCTGCTGGAATCCACCGCGCTTTCGACGCTGGGGGGGATTGTCGGATTAATCACAGGATCAGGGATTGCCGG
ACTACTGGGAATACTGGTCAGCGATTTGCCCATCAGCATCCCGTGGCGCTATGTCATCGCGGCATTGCTCCTGTCAGGGG
TAATCGGGCTGGCAGCGGGCATTGTTCCCGCCATACGCGCAGCCCGTCTTAATCCGGTGGATGCCCTACGCGCTGAGTAA

Upstream 100 bases:

>100_bases
TAGGAGTCGCAGTATTGGCTGGCGTTCTGGCGGGATTATTACCGGCAATCCGTGCGGCGAAACTGGATCCGGTTGATGCA
CTTGGCAAGCGATAAAGTCG

Downstream 100 bases:

>100_bases
AGCCTGGCTTCAGTGATTTTTTACGTAATCCACTAACTTCTGGAAGGAAAATAGATTGTCCTGTTTCTGTAACGGGTTAT
GACATTGTGCACAATTCAGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MNLVESLRFALRALTAHRTRTFLSASGIAIGIAAVILLTSIGAGIQRFVLSEFTQFGTNIVNITPGKTRTRGASTGSISS
VRLLTIEDSLALKSSRHAVYTNATVTGNAEVRGNGHSRRVTVYGQGPDFDRAFNMHTAIGQFLPADDPRNPRAFAVLGAK
VHKELYGSTNPLGSVLQVGGSRFRIIGVMASKGQVLGFDLDDTVYIPTARALEVFNREGVMEIQVVYPPATPLDEVTQDI
KRIMLKRHGREDFTITPQQQMLSTLSTVLNVLTFAVAVLGGISLLVGAVGMITLMHITVTERMAEIGLLNALGATPMRIR
ILFLLESTALSTLGGIVGLITGSGIAGLLGILVSDLPISIPWRYVIAALLLSGVIGLAAGIVPAIRAARLNPVDALRAE

Sequences:

>Translated_399_residues
MNLVESLRFALRALTAHRTRTFLSASGIAIGIAAVILLTSIGAGIQRFVLSEFTQFGTNIVNITPGKTRTRGASTGSISS
VRLLTIEDSLALKSSRHAVYTNATVTGNAEVRGNGHSRRVTVYGQGPDFDRAFNMHTAIGQFLPADDPRNPRAFAVLGAK
VHKELYGSTNPLGSVLQVGGSRFRIIGVMASKGQVLGFDLDDTVYIPTARALEVFNREGVMEIQVVYPPATPLDEVTQDI
KRIMLKRHGREDFTITPQQQMLSTLSTVLNVLTFAVAVLGGISLLVGAVGMITLMHITVTERMAEIGLLNALGATPMRIR
ILFLLESTALSTLGGIVGLITGSGIAGLLGILVSDLPISIPWRYVIAALLLSGVIGLAAGIVPAIRAARLNPVDALRAE
>Mature_399_residues
MNLVESLRFALRALTAHRTRTFLSASGIAIGIAAVILLTSIGAGIQRFVLSEFTQFGTNIVNITPGKTRTRGASTGSISS
VRLLTIEDSLALKSSRHAVYTNATVTGNAEVRGNGHSRRVTVYGQGPDFDRAFNMHTAIGQFLPADDPRNPRAFAVLGAK
VHKELYGSTNPLGSVLQVGGSRFRIIGVMASKGQVLGFDLDDTVYIPTARALEVFNREGVMEIQVVYPPATPLDEVTQDI
KRIMLKRHGREDFTITPQQQMLSTLSTVLNVLTFAVAVLGGISLLVGAVGMITLMHITVTERMAEIGLLNALGATPMRIR
ILFLLESTALSTLGGIVGLITGSGIAGLLGILVSDLPISIPWRYVIAALLLSGVIGLAAGIVPAIRAARLNPVDALRAE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=397, Percent_Identity=27.9596977329975, Blast_Score=135, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 42428; Mature: 42428

Theoretical pI: Translated: 10.65; Mature: 10.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVESLRFALRALTAHRTRTFLSASGIAIGIAAVILLTSIGAGIQRFVLSEFTQFGTNI
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VNITPGKTRTRGASTGSISSVRLLTIEDSLALKSSRHAVYTNATVTGNAEVRGNGHSRRV
EEECCCCCCCCCCCCCCCCEEEEEEEECHHHHCCCCCEEEEEEEEECCCEEECCCCCEEE
TVYGQGPDFDRAFNMHTAIGQFLPADDPRNPRAFAVLGAKVHKELYGSTNPLGSVLQVGG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHCCC
SRFRIIGVMASKGQVLGFDLDDTVYIPTARALEVFNREGVMEIQVVYPPATPLDEVTQDI
CEEEEEEEEECCCCEEEECCCCCEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHH
KRIMLKRHGREDFTITPQQQMLSTLSTVLNVLTFAVAVLGGISLLVGAVGMITLMHITVT
HHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMAEIGLLNALGATPMRIRILFLLESTALSTLGGIVGLITGSGIAGLLGILVSDLPISI
HHHHHHHHHHHCCCCCHHEEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PWRYVIAALLLSGVIGLAAGIVPAIRAARLNPVDALRAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC
>Mature Secondary Structure
MNLVESLRFALRALTAHRTRTFLSASGIAIGIAAVILLTSIGAGIQRFVLSEFTQFGTNI
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEE
VNITPGKTRTRGASTGSISSVRLLTIEDSLALKSSRHAVYTNATVTGNAEVRGNGHSRRV
EEECCCCCCCCCCCCCCCCEEEEEEEECHHHHCCCCCEEEEEEEEECCCEEECCCCCEEE
TVYGQGPDFDRAFNMHTAIGQFLPADDPRNPRAFAVLGAKVHKELYGSTNPLGSVLQVGG
EEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEHHHHHHHHHCCCCCCHHHHHHCCC
SRFRIIGVMASKGQVLGFDLDDTVYIPTARALEVFNREGVMEIQVVYPPATPLDEVTQDI
CEEEEEEEEECCCCEEEECCCCCEECCCHHHHHHHCCCCCEEEEEEECCCCCHHHHHHHH
KRIMLKRHGREDFTITPQQQMLSTLSTVLNVLTFAVAVLGGISLLVGAVGMITLMHITVT
HHHHHHHCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERMAEIGLLNALGATPMRIRILFLLESTALSTLGGIVGLITGSGIAGLLGILVSDLPISI
HHHHHHHHHHHCCCCCHHEEEEEEEHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCC
PWRYVIAALLLSGVIGLAAGIVPAIRAARLNPVDALRAE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA