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The map label for this gene is potC [H]

Identifier: 114331323

GI number: 114331323

Start: 1392975

End: 1393760

Strand: Direct

Name: potC [H]

Synonym: Neut_1330

Alternate gene names: 114331323

Gene position: 1392975-1393760 (Clockwise)

Preceding gene: 114331322

Following gene: 114331324

Centisome position: 52.35

GC content: 47.33

Gene sequence:

>786_bases
ATGAAACACACCAATCTCACCCTGTGGCTTGCTGCCAGTCTGGTTTATATTTTTCTTTATATTCCACTGGTTATTGTCGT
CGTTTACTCGTTCAATGATTCCCGCCTGAATGCGGAATGGGTCGGCTTTACGCTGGACTGGTACTACAAGCTGTTTAATA
ACCAGGAAATGCTGCTGGCCGCGCGTAATTCATTGATTATCGCTGTCAGCGCCAGTCTGCTTGCAACCATACTGGGAACC
ATGGCGGGATTAGCCATTCATCGCTACCGGATCAAGGTATTGCCGTTTCTTGCATTTGCACCAATTGCCATGCCGGAAAT
CCTGCTGGGAGTTTCGCTGCTGCTGTTCTTTCTACAAGTACTGAATCTGACGTTAGGTCTGGTTTCGATCATCATTGCCC
ACACAACATTTTGTGTTGGTTTCGTCGCCATTATTGTGCGTGCTCGGCTGCAAGGTATGGATGACAGTATTTTTGAAGCA
GCCCGCGATCTGGGCGCAACACCCTGGCAAACATTCAGGCTGATTACTCTGCCGCTGATCATGCCCGCAGTCATCGCCGG
GGCGCTCATGTCGTTTACGCTGTCAATTGATGATTTTGTTATTACTTTCTTCACCAAAGGCATTGGTGAACCGATTCTGC
CGATTCAGATCTACACCATGATCAAAATTGCTGTTACGCCCGAAGTTAACGCCATTTCTACATTATTCATGTTGTTGACA
CTGGTATTGATCATCATCGCTAATCGTCTGGATTCCGGCATCTTGCAGGGGGAAAAGAAATCGTGA

Upstream 100 bases:

>100_bases
TTGTCCATCATGCTCATGCTGGCCGTGCTGTGTGTGACTGGATTATTCACTCTACTGGCTCGCCCTCGTGTACCCAGGTA
AATAAATCTCCTGTTCTGAT

Downstream 100 bases:

>100_bases
AACTCGGCTACACCCTGATGGGTCTCTTTTGCCTGCTGATCATCGCGCTGACCGGCTGCACATCCGAAGATCAGGTTGCG
GGTAATTTGTCCGGCAAAAA

Product: binding-protein-dependent transport systems inner membrane component

Products: Phosphate; putrescine [Cytoplasm]; ADP; spermidine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MKHTNLTLWLAASLVYIFLYIPLVIVVVYSFNDSRLNAEWVGFTLDWYYKLFNNQEMLLAARNSLIIAVSASLLATILGT
MAGLAIHRYRIKVLPFLAFAPIAMPEILLGVSLLLFFLQVLNLTLGLVSIIIAHTTFCVGFVAIIVRARLQGMDDSIFEA
ARDLGATPWQTFRLITLPLIMPAVIAGALMSFTLSIDDFVITFFTKGIGEPILPIQIYTMIKIAVTPEVNAISTLFMLLT
LVLIIIANRLDSGILQGEKKS

Sequences:

>Translated_261_residues
MKHTNLTLWLAASLVYIFLYIPLVIVVVYSFNDSRLNAEWVGFTLDWYYKLFNNQEMLLAARNSLIIAVSASLLATILGT
MAGLAIHRYRIKVLPFLAFAPIAMPEILLGVSLLLFFLQVLNLTLGLVSIIIAHTTFCVGFVAIIVRARLQGMDDSIFEA
ARDLGATPWQTFRLITLPLIMPAVIAGALMSFTLSIDDFVITFFTKGIGEPILPIQIYTMIKIAVTPEVNAISTLFMLLT
LVLIIIANRLDSGILQGEKKS
>Mature_261_residues
MKHTNLTLWLAASLVYIFLYIPLVIVVVYSFNDSRLNAEWVGFTLDWYYKLFNNQEMLLAARNSLIIAVSASLLATILGT
MAGLAIHRYRIKVLPFLAFAPIAMPEILLGVSLLLFFLQVLNLTLGLVSIIIAHTTFCVGFVAIIVRARLQGMDDSIFEA
ARDLGATPWQTFRLITLPLIMPAVIAGALMSFTLSIDDFVITFFTKGIGEPILPIQIYTMIKIAVTPEVNAISTLFMLLT
LVLIIIANRLDSGILQGEKKS

Specific function: Required for the activity of the bacterial periplasmic transport system of putrescine and spermidine [H]

COG id: COG1177

COG function: function code E; ABC-type spermidine/putrescine transport system, permease component II

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1787368, Length=234, Percent_Identity=42.7350427350427, Blast_Score=199, Evalue=2e-52,
Organism=Escherichia coli, GI1787081, Length=233, Percent_Identity=42.4892703862661, Blast_Score=166, Evalue=1e-42,
Organism=Escherichia coli, GI1787714, Length=244, Percent_Identity=36.0655737704918, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1788764, Length=174, Percent_Identity=28.735632183908, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 28925; Mature: 28925

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHTNLTLWLAASLVYIFLYIPLVIVVVYSFNDSRLNAEWVGFTLDWYYKLFNNQEMLLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHCCCCEEEE
ARNSLIIAVSASLLATILGTMAGLAIHRYRIKVLPFLAFAPIAMPEILLGVSLLLFFLQV
ECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTLGLVSIIIAHTTFCVGFVAIIVRARLQGMDDSIFEAARDLGATPWQTFRLITLPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MPAVIAGALMSFTLSIDDFVITFFTKGIGEPILPIQIYTMIKIAVTPEVNAISTLFMLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHH
LVLIIIANRLDSGILQGEKKS
HHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MKHTNLTLWLAASLVYIFLYIPLVIVVVYSFNDSRLNAEWVGFTLDWYYKLFNNQEMLLA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHEEHHHHHHHHHHCCCCEEEE
ARNSLIIAVSASLLATILGTMAGLAIHRYRIKVLPFLAFAPIAMPEILLGVSLLLFFLQV
ECCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LNLTLGLVSIIIAHTTFCVGFVAIIVRARLQGMDDSIFEAARDLGATPWQTFRLITLPLI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHH
MPAVIAGALMSFTLSIDDFVITFFTKGIGEPILPIQIYTMIKIAVTPEVNAISTLFMLLT
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCHHHHHHHHHHHH
LVLIIIANRLDSGILQGEKKS
HHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Putrescine [Periplasm]; H2O; ATP; spermidine [Periplasm] [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] ATP + spermidine [Periplasm] + H2O = ADP + phosphate + spermidine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]