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The map label for this gene is comL [H]

Identifier: 114331226

GI number: 114331226

Start: 1286548

End: 1287321

Strand: Reverse

Name: comL [H]

Synonym: Neut_1229

Alternate gene names: 114331226

Gene position: 1287321-1286548 (Counterclockwise)

Preceding gene: 114331230

Following gene: 114331225

Centisome position: 48.38

GC content: 45.22

Gene sequence:

>774_bases
ATGGTATTGTTGGCCGCATGTGGCATTCTGTCCGAAAAAACGGTTGATAACAGCCAGTGGTCTGCGAGTAAATTTTATAT
CGAAGCCAAAAATGAGCTTAACGAGGGTAATTATTCAGCTGCAGTCAAATTGTTCGAAGCACTGGAAGCCCGTTATCCCT
ATGGACGGTTTGCTCAACAGGCACAGCTTGAAATAGCTTACGCCTACTATAAGGATCAGGAACAGGCCTCAGCCATTGCA
GCGGCAGACCGGTTTATCCAGCTCTACCCACATCATCATAATATTGATTATGCTTATTATATCAAGGGACTCGCTAGCTT
TAACGATGATCAAGGTCTATTGGGGTATATAACCACCAAAATCATTAAGCAGGATTTGAGCGAACGGGATGCAAAGGCTT
CAAGAGAATCATTTGAAGATTTCAAGCTGCTGGTAACCCGTTATCCGGATAGTAAATATACGCCTGATGCACTGCAGCGC
ATGGCTTATCTGGTCAATGCGCTGGCAAGAGGTGAAATTCATGTCGCCCGGTATTATATGAAACGGAAAGCTTACATAGC
AGCTCTCAGGCGTGCGCAGTTTGTACTGGAAGAATACCCGCAAACGCCTGCGACAGAAGAAGCGCTGTACATCATGGCAA
GCGCCTACAATGAGTTGGGCCTGATCGATTTGCGCGAAGATACAGAAAAAGTCATCAAAAAAAATTTCCCGGAAAGTGCT
TACCTTACAGATTCCGGTTCGCTGGTAGAAAAACCCTGGTGGAAAATCTGGTAA

Upstream 100 bases:

>100_bases
GCTGGCTGTGGATGAATCAGGCTTTGCGCTATAATTGCGTCCATCTTGCCCGTTATTGAGATTATTCATTATGTTGCGAC
AATTTTTGGCAGGGTGGTTG

Downstream 100 bases:

>100_bases
TAAATTGAATTTTTCTACATCAGGAGCGCATACCAATTTCGTTCATCCGGAATTTTGGCGTAAAATGCAGCCCCCGCCCT
GGTAGCTCAGGGGATAGAGC

Product: TPR repeat-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MVLLAACGILSEKTVDNSQWSASKFYIEAKNELNEGNYSAAVKLFEALEARYPYGRFAQQAQLEIAYAYYKDQEQASAIA
AADRFIQLYPHHHNIDYAYYIKGLASFNDDQGLLGYITTKIIKQDLSERDAKASRESFEDFKLLVTRYPDSKYTPDALQR
MAYLVNALARGEIHVARYYMKRKAYIAALRRAQFVLEEYPQTPATEEALYIMASAYNELGLIDLREDTEKVIKKNFPESA
YLTDSGSLVEKPWWKIW

Sequences:

>Translated_257_residues
MVLLAACGILSEKTVDNSQWSASKFYIEAKNELNEGNYSAAVKLFEALEARYPYGRFAQQAQLEIAYAYYKDQEQASAIA
AADRFIQLYPHHHNIDYAYYIKGLASFNDDQGLLGYITTKIIKQDLSERDAKASRESFEDFKLLVTRYPDSKYTPDALQR
MAYLVNALARGEIHVARYYMKRKAYIAALRRAQFVLEEYPQTPATEEALYIMASAYNELGLIDLREDTEKVIKKNFPESA
YLTDSGSLVEKPWWKIW
>Mature_257_residues
MVLLAACGILSEKTVDNSQWSASKFYIEAKNELNEGNYSAAVKLFEALEARYPYGRFAQQAQLEIAYAYYKDQEQASAIA
AADRFIQLYPHHHNIDYAYYIKGLASFNDDQGLLGYITTKIIKQDLSERDAKASRESFEDFKLLVTRYPDSKYTPDALQR
MAYLVNALARGEIHVARYYMKRKAYIAALRRAQFVLEEYPQTPATEEALYIMASAYNELGLIDLREDTEKVIKKNFPESA
YLTDSGSLVEKPWWKIW

Specific function: Required for efficient transformation of Neisseria gonorrhoeae by species-related DNA [H]

COG id: COG4105

COG function: function code R; DNA uptake lipoprotein

Gene ontology:

Cell location: Cell membrane; Lipid-anchor [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0169 (ComL) family [H]

Homologues:

Organism=Escherichia coli, GI1788947, Length=235, Percent_Identity=40, Blast_Score=173, Evalue=9e-45,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017689
- InterPro:   IPR011990 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 29605; Mature: 29605

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLLAACGILSEKTVDNSQWSASKFYIEAKNELNEGNYSAAVKLFEALEARYPYGRFAQQ
CEEEEECCHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
AQLEIAYAYYKDQEQASAIAAADRFIQLYPHHHNIDYAYYIKGLASFNDDQGLLGYITTK
HHHEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
IIKQDLSERDAKASRESFEDFKLLVTRYPDSKYTPDALQRMAYLVNALARGEIHVARYYM
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KRKAYIAALRRAQFVLEEYPQTPATEEALYIMASAYNELGLIDLREDTEKVIKKNFPESA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCE
YLTDSGSLVEKPWWKIW
EECCCCCCCCCCCCCCC
>Mature Secondary Structure
MVLLAACGILSEKTVDNSQWSASKFYIEAKNELNEGNYSAAVKLFEALEARYPYGRFAQQ
CEEEEECCHHHHCCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCHHHHHH
AQLEIAYAYYKDQEQASAIAAADRFIQLYPHHHNIDYAYYIKGLASFNDDQGLLGYITTK
HHHEEEEEECCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHH
IIKQDLSERDAKASRESFEDFKLLVTRYPDSKYTPDALQRMAYLVNALARGEIHVARYYM
HHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KRKAYIAALRRAQFVLEEYPQTPATEEALYIMASAYNELGLIDLREDTEKVIKKNFPESA
HHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCCCCE
YLTDSGSLVEKPWWKIW
EECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8830266 [H]