Click here to switch to the map view.

The map label for this gene is surA [H]

Identifier: 114331215

GI number: 114331215

Start: 1274667

End: 1275941

Strand: Direct

Name: surA [H]

Synonym: Neut_1217

Alternate gene names: 114331215

Gene position: 1274667-1275941 (Clockwise)

Preceding gene: 114331214

Following gene: 114331216

Centisome position: 47.9

GC content: 47.84

Gene sequence:

>1275_bases
ATGTGGGTGGTAAATATTTCTGCACAAAATTTCCATCCCGGGAACGACATCAAGCCAATTGATCGTATTGTGGCTGTGGT
TAATGAGGAAGTGATCACCCAGCAGGAAACTAATGAGCTGCTGCAAAATACAATCCAGCAATTGCAGAAACAGAATATAC
AGTTGCCTAGCATGGAGGTTCTGGAGAAACAGTTATTGGAACGCCTGATCATCAAACGAATACAACTGCAACGCGCCAAG
GAAGTCGGGTTATCTGTTAGTGACAACGATCTTGATCAAACCTTGCGCCGGATTGTTCAAGATAACCACCTTACCATGGA
TGAGTTCCGGCAGGTGCTTTTGCAGGAAGGAACTAATTTAAGCCTATTCCGGGATGAAATTCGCGATGAAATTTTGATGT
CCCGACTGAAAGAACAGGAAATAAACAGCCGTGTCAATGTAACCGAGAGTGAAATCGATAACTTTCTGGAAAATCAGGCT
AACTCACCGGCGGCTAACGAAGAGTATCGCATCGCGCATATCCTGGTGCAGACTTCAGAACAGATGGATGAGGCACAGAT
CAATACACGCCACAAACGTGCCGAGGCAGCCTATGAAGATCTTAGGCAAGGCATCAGTTTTGCACAGGTATCTGCTGAAT
ATTCCGATGCAACGGATGCGATGCAGGGAGGTGAGCTGGGCTGGCGCCCACTTGGCCAGATAGGTTCACCCTTTGCTGAA
TTGCTGTTGCAAATGCAACCGGGAGAGATTACTCCTGTGGTACGCAGCCCGATTGGGTTTCATATTCTTAAGTTGCTCGA
ACGCCGACAACAGGAAAAGTCGGTAACAATCATTGAACAGACGCATGCACAGCATATTTTAATCAAGGTCAGTGAAATAA
TTTCTGAAGAAGACGCGCACCAGCTAATTGATCAAATCATGGAACGCATTCATAACGGGGCGGATTTTATGGAGATGGCC
AAGGCGCATTCGGAAGATGCCAGTGCATCTGCCGGGGGAGATCTGGGTTGGGTTTCTCCAGGAGATACCGTGCCTGAGTT
TGAACAAGCGATGAATGCATTGCTGCCAGGGCAAATCAGCCAACCCGTGCGCACATCTTTTGGCTGGCATCTGATCAAGG
TCATTGAGCGGCGCTCACAAGATGTAAGCGAGCAGAAACAGCGTGAAACAGCGCGCAAGACTATCCATGCACGCAAAGCA
GATGCCGTTACGCAGGAATGGTTGCAGCAGCTCAGAGATCAGGCCTATGTGGAATATAAAGTTGAAGGCATCTGA

Upstream 100 bases:

>100_bases
GTATTCCAGGTTACGTAAGGACAGACTTGCAATGATCCGATTAAGCCAGTTTATACAGTCAAAGTTTGGAAAGTTCGCAT
TGATCGGAGCTTTTACCACT

Downstream 100 bases:

>100_bases
GCGAATGTACAACAATGATGAAGTGATCTTTTTTACAGATAGGCTTGATTTACTGGCTGGATCTTCAATATGACAATTGC
TTCCATCCCAAGATTGGTGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MWVVNISAQNFHPGNDIKPIDRIVAVVNEEVITQQETNELLQNTIQQLQKQNIQLPSMEVLEKQLLERLIIKRIQLQRAK
EVGLSVSDNDLDQTLRRIVQDNHLTMDEFRQVLLQEGTNLSLFRDEIRDEILMSRLKEQEINSRVNVTESEIDNFLENQA
NSPAANEEYRIAHILVQTSEQMDEAQINTRHKRAEAAYEDLRQGISFAQVSAEYSDATDAMQGGELGWRPLGQIGSPFAE
LLLQMQPGEITPVVRSPIGFHILKLLERRQQEKSVTIIEQTHAQHILIKVSEIISEEDAHQLIDQIMERIHNGADFMEMA
KAHSEDASASAGGDLGWVSPGDTVPEFEQAMNALLPGQISQPVRTSFGWHLIKVIERRSQDVSEQKQRETARKTIHARKA
DAVTQEWLQQLRDQAYVEYKVEGI

Sequences:

>Translated_424_residues
MWVVNISAQNFHPGNDIKPIDRIVAVVNEEVITQQETNELLQNTIQQLQKQNIQLPSMEVLEKQLLERLIIKRIQLQRAK
EVGLSVSDNDLDQTLRRIVQDNHLTMDEFRQVLLQEGTNLSLFRDEIRDEILMSRLKEQEINSRVNVTESEIDNFLENQA
NSPAANEEYRIAHILVQTSEQMDEAQINTRHKRAEAAYEDLRQGISFAQVSAEYSDATDAMQGGELGWRPLGQIGSPFAE
LLLQMQPGEITPVVRSPIGFHILKLLERRQQEKSVTIIEQTHAQHILIKVSEIISEEDAHQLIDQIMERIHNGADFMEMA
KAHSEDASASAGGDLGWVSPGDTVPEFEQAMNALLPGQISQPVRTSFGWHLIKVIERRSQDVSEQKQRETARKTIHARKA
DAVTQEWLQQLRDQAYVEYKVEGI
>Mature_424_residues
MWVVNISAQNFHPGNDIKPIDRIVAVVNEEVITQQETNELLQNTIQQLQKQNIQLPSMEVLEKQLLERLIIKRIQLQRAK
EVGLSVSDNDLDQTLRRIVQDNHLTMDEFRQVLLQEGTNLSLFRDEIRDEILMSRLKEQEINSRVNVTESEIDNFLENQA
NSPAANEEYRIAHILVQTSEQMDEAQINTRHKRAEAAYEDLRQGISFAQVSAEYSDATDAMQGGELGWRPLGQIGSPFAE
LLLQMQPGEITPVVRSPIGFHILKLLERRQQEKSVTIIEQTHAQHILIKVSEIISEEDAHQLIDQIMERIHNGADFMEMA
KAHSEDASASAGGDLGWVSPGDTVPEFEQAMNALLPGQISQPVRTSFGWHLIKVIERRSQDVSEQKQRETARKTIHARKA
DAVTQEWLQQLRDQAYVEYKVEGI

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=367, Percent_Identity=34.3324250681199, Blast_Score=240, Evalue=1e-64,
Organism=Escherichia coli, GI1790211, Length=95, Percent_Identity=40, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 48397; Mature: 48397

Theoretical pI: Translated: 4.69; Mature: 4.69

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWVVNISAQNFHPGNDIKPIDRIVAVVNEEVITQQETNELLQNTIQQLQKQNIQLPSMEV
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LEKQLLERLIIKRIQLQRAKEVGLSVSDNDLDQTLRRIVQDNHLTMDEFRQVLLQEGTNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SLFRDEIRDEILMSRLKEQEINSRVNVTESEIDNFLENQANSPAANEEYRIAHILVQTSE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QMDEAQINTRHKRAEAAYEDLRQGISFAQVSAEYSDATDAMQGGELGWRPLGQIGSPFAE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHH
LLLQMQPGEITPVVRSPIGFHILKLLERRQQEKSVTIIEQTHAQHILIKVSEIISEEDAH
HHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
QLIDQIMERIHNGADFMEMAKAHSEDASASAGGDLGWVSPGDTVPEFEQAMNALLPGQIS
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
QPVRTSFGWHLIKVIERRSQDVSEQKQRETARKTIHARKADAVTQEWLQQLRDQAYVEYK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEE
VEGI
ECCC
>Mature Secondary Structure
MWVVNISAQNFHPGNDIKPIDRIVAVVNEEVITQQETNELLQNTIQQLQKQNIQLPSMEV
CEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
LEKQLLERLIIKRIQLQRAKEVGLSVSDNDLDQTLRRIVQDNHLTMDEFRQVLLQEGTNL
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
SLFRDEIRDEILMSRLKEQEINSRVNVTESEIDNFLENQANSPAANEEYRIAHILVQTSE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
QMDEAQINTRHKRAEAAYEDLRQGISFAQVSAEYSDATDAMQGGELGWRPLGQIGSPFAE
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCHHHH
LLLQMQPGEITPVVRSPIGFHILKLLERRQQEKSVTIIEQTHAQHILIKVSEIISEEDAH
HHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHH
QLIDQIMERIHNGADFMEMAKAHSEDASASAGGDLGWVSPGDTVPEFEQAMNALLPGQIS
HHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
QPVRTSFGWHLIKVIERRSQDVSEQKQRETARKTIHARKADAVTQEWLQQLRDQAYVEYK
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHEE
VEGI
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]