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The map label for this gene is pdxA [H]

Identifier: 114331216

GI number: 114331216

Start: 1276011

End: 1277048

Strand: Direct

Name: pdxA [H]

Synonym: Neut_1218

Alternate gene names: 114331216

Gene position: 1276011-1277048 (Clockwise)

Preceding gene: 114331215

Following gene: 114331217

Centisome position: 47.95

GC content: 49.42

Gene sequence:

>1038_bases
ATGACAATTGCTTCCATCCCAAGATTGGTGGTAACTGCCGGTGAACCCGCTGGTATCGGCCCGGATTTAAGCGTGCAAGT
CGCACAACAGGATCTGCCTTATCAACTGACAGTTATCGCTGATCGCAACGTATTGGAACAGCGTGCAGAAAAACTGAGAT
TACCTTTGCAGGTATTGGAAGTTGATTCGATAGACGATTTGCCTTGCCTGCCGCCACATAAAGCGGGGTTTGTACATGTA
CTGCATGTGCCCGTCAAAAACCCGGTGGTAACAAGTCAGCTGGATGTTGGCAATGCAGCTTATGTACTGACAACATTACA
GTTGGCGGTAGCAGCCTGCAGCACCCGCAAGGCCGATGCCATAGTCACGGCGCCGGTACATAAAGGCATTATCAGTGAAT
CAGGCATTCCATTCTCCGGGCATACTGAATATCTGTCAGAGTTGACAAACAGCCATGCCGTTATGATGCTGGCCGGTGCC
GGTATGCGCGTTACTCTTGCCACAACCCATTTGCCGCTTAAAGATGTTCCTGCTGCGATTACGCCTGAGCGACTGGAACA
AAAGTTGCGTATTATTCATCATGATCTGGTCACACGGTTTGTAATTAAAAATCCGTGCATTGCCGTGGCAGGACTGAATC
CTCACGCTGGAGAATCCGGGCATCTTGGCCGTGAGGAAATCGACATTATTATTCCAGTGCTGACAAAACTGCGTAATGAA
GGGATGAATCTGTTGGGTCCGCTACCGGCGGATACTCTGTTTAATCCTCCCAAACTCAAGAAATATGACTGCATCTTTGC
CATGTATCACGATCAGGGATTGCCGACACTCAAACATGCCAGTTTTGGCCATGGTGTGAATATCAGCCTTGGAATGCCCA
TTATTCGCACATCAGTGGATCATGGTACGGCGTTGGAGCTGGCCGGAACTGGACAGGCCGATCCTGGCAGCATACATGCT
GCCATTGAAATGGCGTTGACGCTCGTCAGGAACACCAGAAACAACTCTCTGCAGGCAAACCAACAATCTGAGAATTAA

Upstream 100 bases:

>100_bases
CTATGTGGAATATAAAGTTGAAGGCATCTGAGCGAATGTACAACAATGATGAAGTGATCTTTTTTACAGATAGGCTTGAT
TTACTGGCTGGATCTTCAAT

Downstream 100 bases:

>100_bases
CATGCGGCATATTCCCCGCAGGCGTTTTGGCCAGCATTTTCTGGTTGATCATCACATCATCGCCGAGATCATTCACATCA
TTTGTCCACTACCAGGCGAC

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 345; Mature: 344

Protein sequence:

>345_residues
MTIASIPRLVVTAGEPAGIGPDLSVQVAQQDLPYQLTVIADRNVLEQRAEKLRLPLQVLEVDSIDDLPCLPPHKAGFVHV
LHVPVKNPVVTSQLDVGNAAYVLTTLQLAVAACSTRKADAIVTAPVHKGIISESGIPFSGHTEYLSELTNSHAVMMLAGA
GMRVTLATTHLPLKDVPAAITPERLEQKLRIIHHDLVTRFVIKNPCIAVAGLNPHAGESGHLGREEIDIIIPVLTKLRNE
GMNLLGPLPADTLFNPPKLKKYDCIFAMYHDQGLPTLKHASFGHGVNISLGMPIIRTSVDHGTALELAGTGQADPGSIHA
AIEMALTLVRNTRNNSLQANQQSEN

Sequences:

>Translated_345_residues
MTIASIPRLVVTAGEPAGIGPDLSVQVAQQDLPYQLTVIADRNVLEQRAEKLRLPLQVLEVDSIDDLPCLPPHKAGFVHV
LHVPVKNPVVTSQLDVGNAAYVLTTLQLAVAACSTRKADAIVTAPVHKGIISESGIPFSGHTEYLSELTNSHAVMMLAGA
GMRVTLATTHLPLKDVPAAITPERLEQKLRIIHHDLVTRFVIKNPCIAVAGLNPHAGESGHLGREEIDIIIPVLTKLRNE
GMNLLGPLPADTLFNPPKLKKYDCIFAMYHDQGLPTLKHASFGHGVNISLGMPIIRTSVDHGTALELAGTGQADPGSIHA
AIEMALTLVRNTRNNSLQANQQSEN
>Mature_344_residues
TIASIPRLVVTAGEPAGIGPDLSVQVAQQDLPYQLTVIADRNVLEQRAEKLRLPLQVLEVDSIDDLPCLPPHKAGFVHVL
HVPVKNPVVTSQLDVGNAAYVLTTLQLAVAACSTRKADAIVTAPVHKGIISESGIPFSGHTEYLSELTNSHAVMMLAGAG
MRVTLATTHLPLKDVPAAITPERLEQKLRIIHHDLVTRFVIKNPCIAVAGLNPHAGESGHLGREEIDIIIPVLTKLRNEG
MNLLGPLPADTLFNPPKLKKYDCIFAMYHDQGLPTLKHASFGHGVNISLGMPIIRTSVDHGTALELAGTGQADPGSIHAA
IEMALTLVRNTRNNSLQANQQSEN

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=329, Percent_Identity=54.1033434650456, Blast_Score=339, Evalue=1e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 37002; Mature: 36871

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIASIPRLVVTAGEPAGIGPDLSVQVAQQDLPYQLTVIADRNVLEQRAEKLRLPLQVLE
CCCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEEE
VDSIDDLPCLPPHKAGFVHVLHVPVKNPVVTSQLDVGNAAYVLTTLQLAVAACSTRKADA
ECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCE
IVTAPVHKGIISESGIPFSGHTEYLSELTNSHAVMMLAGAGMRVTLATTHLPLKDVPAAI
EEECCHHHCHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHCCCCC
TPERLEQKLRIIHHDLVTRFVIKNPCIAVAGLNPHAGESGHLGREEIDIIIPVLTKLRNE
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GMNLLGPLPADTLFNPPKLKKYDCIFAMYHDQGLPTLKHASFGHGVNISLGMPIIRTSVD
CCCEECCCCHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEECCC
HGTALELAGTGQADPGSIHAAIEMALTLVRNTRNNSLQANQQSEN
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure 
TIASIPRLVVTAGEPAGIGPDLSVQVAQQDLPYQLTVIADRNVLEQRAEKLRLPLQVLE
CCCCCCEEEEECCCCCCCCCCCEEEEECCCCCEEEEEEECCHHHHHHHHHHCCCEEEEE
VDSIDDLPCLPPHKAGFVHVLHVPVKNPVVTSQLDVGNAAYVLTTLQLAVAACSTRKADA
ECCCCCCCCCCCCCCCEEEEEEECCCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCE
IVTAPVHKGIISESGIPFSGHTEYLSELTNSHAVMMLAGAGMRVTLATTHLPLKDVPAAI
EEECCHHHCHHCCCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEEEEECCCHHHCCCCC
TPERLEQKLRIIHHDLVTRFVIKNPCIAVAGLNPHAGESGHLGREEIDIIIPVLTKLRNE
CHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHC
GMNLLGPLPADTLFNPPKLKKYDCIFAMYHDQGLPTLKHASFGHGVNISLGMPIIRTSVD
CCCEECCCCHHHCCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCEEEEECCCEEEECCC
HGTALELAGTGQADPGSIHAAIEMALTLVRNTRNNSLQANQQSEN
CCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA