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The map label for this gene is trkH [H]

Identifier: 114331129

GI number: 114331129

Start: 1170253

End: 1171662

Strand: Reverse

Name: trkH [H]

Synonym: Neut_1131

Alternate gene names: 114331129

Gene position: 1171662-1170253 (Counterclockwise)

Preceding gene: 114331130

Following gene: 114331128

Centisome position: 44.03

GC content: 48.58

Gene sequence:

>1410_bases
ATGTTCGGGCTGGTTTTGCTGATTCCCTGTGGCGTTGCCTACTGGATGAAAGATGGATCATTGCCTGTCTTTCTCGAAAC
TTTATTCATCACACTGGGATGTGGCGTAACAATATGGCTGCTGACATACCAGTTTAAACGTGAGTTGCAGATTCGGGACG
GATTTCTGCTGGTTGTACTGGTCTGGCTGTCACTACCTGTGTTCGGAATGCTTCCCTTGTTCTTTTACTTTCCAGAACTC
GGCGTTGCCAAGTCATATTTTGAAGCTGCTTCCGGCCTGACTTCAACCGGCGCAACAGTATTGATGGGGCTTGATGAATT
TCCATACGCTATTAACCTTTGGCGCTGTCTCATGGCTTGGATAGGCGGGATGGGACTAATCGTACTGGCAGTAGCGATTC
TACCCATGCTCGGTGTCGGGGGAAGGAAGCTTTTTAGTGCAGAAATCCCCGGGCCAATCAAGGAATCCCGACTGACACCC
AGAATCGCGGAAACAGCCAAGCGCTTATGGCTGATCTACGCTGCTTTGACTGTTGCCTGCACAATTGCCTACTGGCTGGC
TGGAATGACCACTCTCGATGCCATTGCTCACGCTCTGAGCACACTAGGCCTAGGGGGATTTTCTACCCATGATGCCAGTT
ACGGATACTGGGATTCTCCATTGATCGAAGCCATTGCAATACTGTTCATGCTGATTGCCGGCATCAATTTCTCAGCACAC
TTTGTTGCCTGGCGTGCCAGAAATTTTTCCGCTTACCGCGCTGACCCGGAAGCAAAACTGTATATCTTGATCACGCTAAG
CAGCTGCATCGGCATAACCGGTTTTCTCTGGACCAAAGGTATTTACACGGACCCCCTGGTTGCTCTACGTTATGCTGCTT
TCAATGTGGTCTCCGTTGCCACAACCACTGGCTACAGCAACACTGATTATGCCCTCTGGCCAATTTTCGCTCCGCTCTGG
ATGCTATTTCTATCCGGCTTCTGCACATCCTCAGGCTCGACTGGCGGTGGTATCAAAATGATCCGTGCGCGCATCCTGTT
TCAGCAGTTCTTTCGTGAAATGATTATCATTATGCATCCACGCGCAGTTTCTCTGGTTAAAATTGGTAAAAACATTGTCG
CCAATGAAATTATTTTTGCCATCCTGGCATTTTTATTCGTCTATCTGACCAGCATCGTGCTGATGACACTGGCACTTACA
CTGAGCGGCCTAGACGAAATTACTGCTTTCTCGGCCGCTGTTGCCTGTCTGAATAATCTAGGAGCAGGGTTGGGGAAAAT
CGGGCCATCTATGAACTATGCTTCATTGAATGATTTTCAAATCTGGCTGTGCAGTTTTGCCATGTTTCTGGGCAGATTGG
AATTTTATACGCTGATGATTGTTTTCACCCCCGCCTTCTGGCGGAAATAA

Upstream 100 bases:

>100_bases
TGTTTCAGGTCAATGTTGGTTTTTTGTAATCGCATACTATGAAATATTTCCTGTGAATCACTTCCTTGCGGTAGCCAATA
TCCTGAGCAGGGTAATACTA

Downstream 100 bases:

>100_bases
GGCTGACAGAATATTCAGACCGAATTGAAGCAACCGATAATGCGTTATTATAATAAGGAAAAATAAGCCTGTAGTTAAAA
GGAAAGTTGGACAAGAACGA

Product: cation transporter

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 469; Mature: 469

Protein sequence:

>469_residues
MFGLVLLIPCGVAYWMKDGSLPVFLETLFITLGCGVTIWLLTYQFKRELQIRDGFLLVVLVWLSLPVFGMLPLFFYFPEL
GVAKSYFEAASGLTSTGATVLMGLDEFPYAINLWRCLMAWIGGMGLIVLAVAILPMLGVGGRKLFSAEIPGPIKESRLTP
RIAETAKRLWLIYAALTVACTIAYWLAGMTTLDAIAHALSTLGLGGFSTHDASYGYWDSPLIEAIAILFMLIAGINFSAH
FVAWRARNFSAYRADPEAKLYILITLSSCIGITGFLWTKGIYTDPLVALRYAAFNVVSVATTTGYSNTDYALWPIFAPLW
MLFLSGFCTSSGSTGGGIKMIRARILFQQFFREMIIIMHPRAVSLVKIGKNIVANEIIFAILAFLFVYLTSIVLMTLALT
LSGLDEITAFSAAVACLNNLGAGLGKIGPSMNYASLNDFQIWLCSFAMFLGRLEFYTLMIVFTPAFWRK

Sequences:

>Translated_469_residues
MFGLVLLIPCGVAYWMKDGSLPVFLETLFITLGCGVTIWLLTYQFKRELQIRDGFLLVVLVWLSLPVFGMLPLFFYFPEL
GVAKSYFEAASGLTSTGATVLMGLDEFPYAINLWRCLMAWIGGMGLIVLAVAILPMLGVGGRKLFSAEIPGPIKESRLTP
RIAETAKRLWLIYAALTVACTIAYWLAGMTTLDAIAHALSTLGLGGFSTHDASYGYWDSPLIEAIAILFMLIAGINFSAH
FVAWRARNFSAYRADPEAKLYILITLSSCIGITGFLWTKGIYTDPLVALRYAAFNVVSVATTTGYSNTDYALWPIFAPLW
MLFLSGFCTSSGSTGGGIKMIRARILFQQFFREMIIIMHPRAVSLVKIGKNIVANEIIFAILAFLFVYLTSIVLMTLALT
LSGLDEITAFSAAVACLNNLGAGLGKIGPSMNYASLNDFQIWLCSFAMFLGRLEFYTLMIVFTPAFWRK
>Mature_469_residues
MFGLVLLIPCGVAYWMKDGSLPVFLETLFITLGCGVTIWLLTYQFKRELQIRDGFLLVVLVWLSLPVFGMLPLFFYFPEL
GVAKSYFEAASGLTSTGATVLMGLDEFPYAINLWRCLMAWIGGMGLIVLAVAILPMLGVGGRKLFSAEIPGPIKESRLTP
RIAETAKRLWLIYAALTVACTIAYWLAGMTTLDAIAHALSTLGLGGFSTHDASYGYWDSPLIEAIAILFMLIAGINFSAH
FVAWRARNFSAYRADPEAKLYILITLSSCIGITGFLWTKGIYTDPLVALRYAAFNVVSVATTTGYSNTDYALWPIFAPLW
MLFLSGFCTSSGSTGGGIKMIRARILFQQFFREMIIIMHPRAVSLVKIGKNIVANEIIFAILAFLFVYLTSIVLMTLALT
LSGLDEITAFSAAVACLNNLGAGLGKIGPSMNYASLNDFQIWLCSFAMFLGRLEFYTLMIVFTPAFWRK

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=470, Percent_Identity=44.468085106383, Blast_Score=373, Evalue=1e-104,
Organism=Escherichia coli, GI1787626, Length=471, Percent_Identity=38.4288747346072, Blast_Score=305, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 51677; Mature: 51677

Theoretical pI: Translated: 8.51; Mature: 8.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFGLVLLIPCGVAYWMKDGSLPVFLETLFITLGCGVTIWLLTYQFKRELQIRDGFLLVVL
CCCEEEEHHCCHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHH
VWLSLPVFGMLPLFFYFPELGVAKSYFEAASGLTSTGATVLMGLDEFPYAINLWRCLMAW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
IGGMGLIVLAVAILPMLGVGGRKLFSAEIPGPIKESRLTPRIAETAKRLWLIYAALTVAC
HCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIAYWLAGMTTLDAIAHALSTLGLGGFSTHDASYGYWDSPLIEAIAILFMLIAGINFSAH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FVAWRARNFSAYRADPEAKLYILITLSSCIGITGFLWTKGIYTDPLVALRYAAFNVVSVA
EEEEECCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEE
TTTGYSNTDYALWPIFAPLWMLFLSGFCTSSGSTGGGIKMIRARILFQQFFREMIIIMHP
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RAVSLVKIGKNIVANEIIFAILAFLFVYLTSIVLMTLALTLSGLDEITAFSAAVACLNNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GAGLGKIGPSMNYASLNDFQIWLCSFAMFLGRLEFYTLMIVFTPAFWRK
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC
>Mature Secondary Structure
MFGLVLLIPCGVAYWMKDGSLPVFLETLFITLGCGVTIWLLTYQFKRELQIRDGFLLVVL
CCCEEEEHHCCHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCHHHHHH
VWLSLPVFGMLPLFFYFPELGVAKSYFEAASGLTSTGATVLMGLDEFPYAINLWRCLMAW
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHHH
IGGMGLIVLAVAILPMLGVGGRKLFSAEIPGPIKESRLTPRIAETAKRLWLIYAALTVAC
HCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHH
TIAYWLAGMTTLDAIAHALSTLGLGGFSTHDASYGYWDSPLIEAIAILFMLIAGINFSAH
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCHH
FVAWRARNFSAYRADPEAKLYILITLSSCIGITGFLWTKGIYTDPLVALRYAAFNVVSVA
EEEEECCCCCCCCCCCCCEEEEEEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHEE
TTTGYSNTDYALWPIFAPLWMLFLSGFCTSSGSTGGGIKMIRARILFQQFFREMIIIMHP
EECCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCC
RAVSLVKIGKNIVANEIIFAILAFLFVYLTSIVLMTLALTLSGLDEITAFSAAVACLNNL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHH
GAGLGKIGPSMNYASLNDFQIWLCSFAMFLGRLEFYTLMIVFTPAFWRK
CCCHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]