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The map label for this gene is ubiE [H]

Identifier: 114331057

GI number: 114331057

Start: 1095543

End: 1096358

Strand: Reverse

Name: ubiE [H]

Synonym: Neut_1059

Alternate gene names: 114331057

Gene position: 1096358-1095543 (Counterclockwise)

Preceding gene: 114331058

Following gene: 114331056

Centisome position: 41.2

GC content: 60.42

Gene sequence:

>816_bases
ATGAGCCATCAGCAAAGTCCGAATCCAGCCGAAACATACGAGCAATATTTTGGCCGCACCATCTCTGCCCCTTGGACACA
GGTGCTGCTTGAGTACGCGGCTCCACAGTTTGGTGAACGAGTGCTGGATGTGGCGTGCGGCACGGGCAGTGTAGCACGGC
AAGTCGCACCCCTCGTTGGAGCGGCAGGGAAGGTGGTCGCGCTCGATATCAATCCAGCCATGCTGGCCGTTGCCCGTGCG
CTCCCCGCCCCCTCAGGCGCGCCGATTGCCTGGCTGGAAGGGAATGCGATCAACCTCGACCTGCCGGATAATGCGTTCGA
GCTCGTGCTGTGCCAGCAAGGCTTACAGTTTTTTCCCGATCGCGCCGCGGCCCTGCGAGAGATGCGGCAAGTGCTGATCG
ATGGCGGGCGTGTCGTGATCAGTGTGTGGCAGGCGCTCCACCGCCATCCAGTGTATGAGGCGCTGTTTCAAGCGACCGCA
CGCCACCTCGGTACGACCATTGGCACCGTGGATGTACCCTTTGCATTATGGAATGCCGAAGAACTGCGGACGCTCCTAAG
TGATGCAGGCTTTCAACGTATAGCGATTACGCCACGGTCGCTCACTATTCACCTGCCTGCGCCAGAGCGCTTTGTGCAAC
TCACGGTGCTGGGAGCAGCGACGTCACTCCCAGCGGTAGTGCACTTGGATGCTGCGGCGCGCTCCGCACTCGTGGAGGCG
GTCACCAGCGAGACGCAGGCGGTGGCGCAACGGTACCGAGATGGAGACACGATAACATTTCCGATGTCAACGCACATCGC
AGTGGCATTCAAGTAA

Upstream 100 bases:

>100_bases
CGCCGCGCATGCCAGTATCAGTCATCTGGTAGCACATCATTTCGCATGACCAATGTCCTGGTTGGGCAGCGGTCATCATC
TTGTCAGTGAGGAGAACTCT

Downstream 100 bases:

>100_bases
AGGCTGGCAGGGGGAGTCACCACCCAACAAGGCGTTGCACCCGACCGCCTACAGCCCTACGCTTGTGCTTCGCTTCGGGC
TTCCGGCGGCGGGTGAGCTT

Product: methyltransferase type 11

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: NA

Number of amino acids: Translated: 271; Mature: 270

Protein sequence:

>271_residues
MSHQQSPNPAETYEQYFGRTISAPWTQVLLEYAAPQFGERVLDVACGTGSVARQVAPLVGAAGKVVALDINPAMLAVARA
LPAPSGAPIAWLEGNAINLDLPDNAFELVLCQQGLQFFPDRAAALREMRQVLIDGGRVVISVWQALHRHPVYEALFQATA
RHLGTTIGTVDVPFALWNAEELRTLLSDAGFQRIAITPRSLTIHLPAPERFVQLTVLGAATSLPAVVHLDAAARSALVEA
VTSETQAVAQRYRDGDTITFPMSTHIAVAFK

Sequences:

>Translated_271_residues
MSHQQSPNPAETYEQYFGRTISAPWTQVLLEYAAPQFGERVLDVACGTGSVARQVAPLVGAAGKVVALDINPAMLAVARA
LPAPSGAPIAWLEGNAINLDLPDNAFELVLCQQGLQFFPDRAAALREMRQVLIDGGRVVISVWQALHRHPVYEALFQATA
RHLGTTIGTVDVPFALWNAEELRTLLSDAGFQRIAITPRSLTIHLPAPERFVQLTVLGAATSLPAVVHLDAAARSALVEA
VTSETQAVAQRYRDGDTITFPMSTHIAVAFK
>Mature_270_residues
SHQQSPNPAETYEQYFGRTISAPWTQVLLEYAAPQFGERVLDVACGTGSVARQVAPLVGAAGKVVALDINPAMLAVARAL
PAPSGAPIAWLEGNAINLDLPDNAFELVLCQQGLQFFPDRAAALREMRQVLIDGGRVVISVWQALHRHPVYEALFQATAR
HLGTTIGTVDVPFALWNAEELRTLLSDAGFQRIAITPRSLTIHLPAPERFVQLTVLGAATSLPAVVHLDAAARSALVEAV
TSETQAVAQRYRDGDTITFPMSTHIAVAFK

Specific function: Methyltransferase required for the conversion of dimethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) [H]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiE family [H]

Homologues:

Organism=Escherichia coli, GI48994983, Length=187, Percent_Identity=30.4812834224599, Blast_Score=84, Evalue=8e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004033 [H]

Pfam domain/function: PF01209 Ubie_methyltran [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 29180; Mature: 29049

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQQSPNPAETYEQYFGRTISAPWTQVLLEYAAPQFGERVLDVACGTGSVARQVAPLVG
CCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
AAGKVVALDINPAMLAVARALPAPSGAPIAWLEGNAINLDLPDNAFELVLCQQGLQFFPD
CCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
RAAALREMRQVLIDGGRVVISVWQALHRHPVYEALFQATARHLGTTIGTVDVPFALWNAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEECCCEECCHH
ELRTLLSDAGFQRIAITPRSLTIHLPAPERFVQLTVLGAATSLPAVVHLDAAARSALVEA
HHHHHHHHCCCEEEEEECCEEEEECCCCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHH
VTSETQAVAQRYRDGDTITFPMSTHIAVAFK
HHHHHHHHHHHHCCCCEEEEECCCCEEEEEC
>Mature Secondary Structure 
SHQQSPNPAETYEQYFGRTISAPWTQVLLEYAAPQFGERVLDVACGTGSVARQVAPLVG
CCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
AAGKVVALDINPAMLAVARALPAPSGAPIAWLEGNAINLDLPDNAFELVLCQQGLQFFPD
CCCCEEEEECCHHHHHHHHHCCCCCCCCEEEECCCEEEEECCCCHHHHHHHHHHHHHCCC
RAAALREMRQVLIDGGRVVISVWQALHRHPVYEALFQATARHLGTTIGTVDVPFALWNAE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCHHHHHHHHHHHHHHCCCCCCEECCCEECCHH
ELRTLLSDAGFQRIAITPRSLTIHLPAPERFVQLTVLGAATSLPAVVHLDAAARSALVEA
HHHHHHHHCCCEEEEEECCEEEEECCCCCCEEEEEEEECCCCCCEEEEECHHHHHHHHHH
VTSETQAVAQRYRDGDTITFPMSTHIAVAFK
HHHHHHHHHHHHCCCCEEEEECCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA