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The map label for this gene is mco [H]

Identifier: 114331051

GI number: 114331051

Start: 1088619

End: 1090205

Strand: Reverse

Name: mco [H]

Synonym: Neut_1052

Alternate gene names: 114331051

Gene position: 1090205-1088619 (Counterclockwise)

Preceding gene: 114331056

Following gene: 114331048

Centisome position: 40.97

GC content: 47.64

Gene sequence:

>1587_bases
ATGACCAATACCAACCTTAATCGTCGCCGGTTCTTGCAATATGCCGCAGCTATACCCGGGTTTGCGTTTACAGAAAGCAA
TAAACTCAATAAAACACCCAATAGCGCATTCAAGGCCGACGTTGAAATTGCCCTGACAGCACAAATGACCGAGGTCTCAA
TCCTGCCGGGAGCAAATACCCGTGTTCTTAAATATACCGGAAAATTACTGAAAGGGCCTTCTGGTACGCTTAAAGAACTG
CCCAGCTATCTGGGGCCTGTGCTCAATTTTGAACAAGGCCAGAAAGTCCGAATATTTTTTTACAATCAGATACCAGAGCC
CTGCGTAACGCATTGGCACGGCATGCATGTACCGCAAATTATGGATGGACATCCGATGTATGCAATCAACCAGGGTGAGC
AATATGTATATGAGTTTGAAGTGAAAAACCCGGCTGGTACTAACTGGTATCATTCTCATACACATGAAGTAACTGCTAGA
CAAGTGTATCAGGGTCTCGCCGGACTCATTACTATCACAGACGAGATTGAACGCAAACTGGATCTGCCAAGTGATGAATA
CGATATTCCGCTTATCATCCAGGATCGAACTTTTACATCCGGGAATCAATTGCATTACGCACTGAACATGCATCAGCGTA
TGCAGGGGTTTCTTGGCGATACCATCTTGGCAAATGGCCGGCGTAACCATGTTGTTCCCGTAAAAACGCGTGCCTACCGT
CTTCGTATCCTGAATGGATCAAACTCCAGAATCTACAAACTGGGCTGGAGTGACGGCTCTCCGCTTACCATCATCGGTAC
AGATGGTGGATTACTGGAAAAACCGCAAACCTTCCCCTATATCATGCTTGCCCCAGCAGAACGGGTAGAGCTATGGGTTG
ATTTTAGCGGTCGCAAGCCTGGCTCTGAGCTGGCTCTGCAGACTTTATCCTACCAGGGATTTTCCATGCGCATGGGAGGT
GGAATGGGCATGGGAAGTAATACGATGGACCAGGGAAACAAAGGTACCATCGTCAAATTTGCAATCACCAAACAAGTAAG
TGATTCACCCAGATTGCCTGATACCCTGGTTCCCATACACCGTTTCACTGCGAAGGATGCTTCTAATCCGGATATCGTGG
TGCCAATTGCCATTGGCATGCGTCGTATGACCTTCAATCTCAATGGCCGAACCTTTGACATGCTGGATTATACGAACCAA
GAAAAAATACCAGTAAATACCGTGCAAAGAATCCGGATATCCAATATCAATCCGGGTATCGGAGGGGGTGGGGGCATGGG
TGGCGGGATGCGCGGTGGTCGGGGAGGAGGAATGATGGGGATGATAATGGCGCAGCCGCACCCGATCCATCTTCATGGCC
AGCAATTCCAGATTCTGTCACGCAAACCTGGCCATGCTGACAGTGCTTACGCTGCAATTAAGGATGGATTTATCAACAGT
GGCTGGAAAGATACAGTGCTGGTGATGCCAGGAGAGGAAGTTGAAATCATCAAGCCATTTACGGACTATACCGGGCTATT
TCTTTATCACTGTCATAACCTGGAACATGAAGATATGGGTATGATGCGCAATTTCTTTGTCAGCTGA

Upstream 100 bases:

>100_bases
CTTGCACCGACTGCTACACTTGGTTTCCCAGAACGCCGGGGTTATCTCGAATTAGGTAGAATCTGCTTAAAACTGTCAAT
TATTTAATAAGGTTAATTTT

Downstream 100 bases:

>100_bases
ATCCGGGTTGGTGTTGAGTACAGGCATACAATTTACCTGTGCCGTACTATACGAATACCATCCAACTACCGGCAGTCTTC
AGATTCAGGAAGATCAGCGG

Product: Bilirubin oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MTNTNLNRRRFLQYAAAIPGFAFTESNKLNKTPNSAFKADVEIALTAQMTEVSILPGANTRVLKYTGKLLKGPSGTLKEL
PSYLGPVLNFEQGQKVRIFFYNQIPEPCVTHWHGMHVPQIMDGHPMYAINQGEQYVYEFEVKNPAGTNWYHSHTHEVTAR
QVYQGLAGLITITDEIERKLDLPSDEYDIPLIIQDRTFTSGNQLHYALNMHQRMQGFLGDTILANGRRNHVVPVKTRAYR
LRILNGSNSRIYKLGWSDGSPLTIIGTDGGLLEKPQTFPYIMLAPAERVELWVDFSGRKPGSELALQTLSYQGFSMRMGG
GMGMGSNTMDQGNKGTIVKFAITKQVSDSPRLPDTLVPIHRFTAKDASNPDIVVPIAIGMRRMTFNLNGRTFDMLDYTNQ
EKIPVNTVQRIRISNINPGIGGGGGMGGGMRGGRGGGMMGMIMAQPHPIHLHGQQFQILSRKPGHADSAYAAIKDGFINS
GWKDTVLVMPGEEVEIIKPFTDYTGLFLYHCHNLEHEDMGMMRNFFVS

Sequences:

>Translated_528_residues
MTNTNLNRRRFLQYAAAIPGFAFTESNKLNKTPNSAFKADVEIALTAQMTEVSILPGANTRVLKYTGKLLKGPSGTLKEL
PSYLGPVLNFEQGQKVRIFFYNQIPEPCVTHWHGMHVPQIMDGHPMYAINQGEQYVYEFEVKNPAGTNWYHSHTHEVTAR
QVYQGLAGLITITDEIERKLDLPSDEYDIPLIIQDRTFTSGNQLHYALNMHQRMQGFLGDTILANGRRNHVVPVKTRAYR
LRILNGSNSRIYKLGWSDGSPLTIIGTDGGLLEKPQTFPYIMLAPAERVELWVDFSGRKPGSELALQTLSYQGFSMRMGG
GMGMGSNTMDQGNKGTIVKFAITKQVSDSPRLPDTLVPIHRFTAKDASNPDIVVPIAIGMRRMTFNLNGRTFDMLDYTNQ
EKIPVNTVQRIRISNINPGIGGGGGMGGGMRGGRGGGMMGMIMAQPHPIHLHGQQFQILSRKPGHADSAYAAIKDGFINS
GWKDTVLVMPGEEVEIIKPFTDYTGLFLYHCHNLEHEDMGMMRNFFVS
>Mature_527_residues
TNTNLNRRRFLQYAAAIPGFAFTESNKLNKTPNSAFKADVEIALTAQMTEVSILPGANTRVLKYTGKLLKGPSGTLKELP
SYLGPVLNFEQGQKVRIFFYNQIPEPCVTHWHGMHVPQIMDGHPMYAINQGEQYVYEFEVKNPAGTNWYHSHTHEVTARQ
VYQGLAGLITITDEIERKLDLPSDEYDIPLIIQDRTFTSGNQLHYALNMHQRMQGFLGDTILANGRRNHVVPVKTRAYRL
RILNGSNSRIYKLGWSDGSPLTIIGTDGGLLEKPQTFPYIMLAPAERVELWVDFSGRKPGSELALQTLSYQGFSMRMGGG
MGMGSNTMDQGNKGTIVKFAITKQVSDSPRLPDTLVPIHRFTAKDASNPDIVVPIAIGMRRMTFNLNGRTFDMLDYTNQE
KIPVNTVQRIRISNINPGIGGGGGMGGGMRGGRGGGMMGMIMAQPHPIHLHGQQFQILSRKPGHADSAYAAIKDGFINSG
WKDTVLVMPGEEVEIIKPFTDYTGLFLYHCHNLEHEDMGMMRNFFVS

Specific function: May be involved in copper homeostasis and oxidative stress response [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family [H]

Homologues:

Organism=Escherichia coli, GI1786314, Length=561, Percent_Identity=29.7682709447415, Blast_Score=188, Evalue=8e-49,
Organism=Escherichia coli, GI1789394, Length=540, Percent_Identity=26.8518518518519, Blast_Score=144, Evalue=1e-35,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR002355
- InterPro:   IPR008972 [H]

Pfam domain/function: PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 58826; Mature: 58695

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNTNLNRRRFLQYAAAIPGFAFTESNKLNKTPNSAFKADVEIALTAQMTEVSILPGANT
CCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCC
RVLKYTGKLLKGPSGTLKELPSYLGPVLNFEQGQKVRIFFYNQIPEPCVTHWHGMHVPQI
EEEEECCHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCE
MDGHPMYAINQGEQYVYEFEVKNPAGTNWYHSHTHEVTARQVYQGLAGLITITDEIERKL
ECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHC
DLPSDEYDIPLIIQDRTFTSGNQLHYALNMHQRMQGFLGDTILANGRRNHVVPVKTRAYR
CCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCCCEEECCCCCCEEEEECEEEE
LRILNGSNSRIYKLGWSDGSPLTIIGTDGGLLEKPQTFPYIMLAPAERVELWVDFSGRKP
EEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCC
GSELALQTLSYQGFSMRMGGGMGMGSNTMDQGNKGTIVKFAITKQVSDSPRLPDTLVPIH
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHCCHH
RFTAKDASNPDIVVPIAIGMRRMTFNLNGRTFDMLDYTNQEKIPVNTVQRIRISNINPGI
HEECCCCCCCCEEEEEECCEEEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
GGGGGMGGGMRGGRGGGMMGMIMAQPHPIHLHGQQFQILSRKPGHADSAYAAIKDGFINS
CCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCEEEEECCCCCCCCCHHHHHHCCCCCC
GWKDTVLVMPGEEVEIIKPFTDYTGLFLYHCHNLEHEDMGMMRNFFVS
CCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure 
TNTNLNRRRFLQYAAAIPGFAFTESNKLNKTPNSAFKADVEIALTAQMTEVSILPGANT
CCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCCCCEEEEEEEEEEEEEEEEEEECCCCC
RVLKYTGKLLKGPSGTLKELPSYLGPVLNFEQGQKVRIFFYNQIPEPCVTHWHGMHVPQI
EEEEECCHHHCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHCCCCCCCCCE
MDGHPMYAINQGEQYVYEFEVKNPAGTNWYHSHTHEVTARQVYQGLAGLITITDEIERKL
ECCCCEEEEECCCEEEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEHHHHHHC
DLPSDEYDIPLIIQDRTFTSGNQLHYALNMHQRMQGFLGDTILANGRRNHVVPVKTRAYR
CCCCCCCCEEEEEECCCCCCCCEEEEEECHHHHHHHHHCCCEEECCCCCCEEEEECEEEE
LRILNGSNSRIYKLGWSDGSPLTIIGTDGGLLEKPQTFPYIMLAPAERVELWVDFSGRKP
EEEEECCCCEEEEEECCCCCCEEEEECCCCCCCCCCCCCEEEECCCCEEEEEEEECCCCC
GSELALQTLSYQGFSMRMGGGMGMGSNTMDQGNKGTIVKFAITKQVSDSPRLPDTLVPIH
CHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCCHHCCHH
RFTAKDASNPDIVVPIAIGMRRMTFNLNGRTFDMLDYTNQEKIPVNTVQRIRISNINPGI
HEECCCCCCCCEEEEEECCEEEEEEEECCCEEEEECCCCCCCCCCCCEEEEEECCCCCCC
GGGGGMGGGMRGGRGGGMMGMIMAQPHPIHLHGQQFQILSRKPGHADSAYAAIKDGFINS
CCCCCCCCCCCCCCCCCEEEEEEECCCEEEECCCEEEEECCCCCCCCCHHHHHHCCCCCC
GWKDTVLVMPGEEVEIIKPFTDYTGLFLYHCHNLEHEDMGMMRNFFVS
CCCCEEEEECCCCEEEEECCCCCCCEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA