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The map label for this gene is hemX [H]

Identifier: 114331038

GI number: 114331038

Start: 1076843

End: 1077871

Strand: Direct

Name: hemX [H]

Synonym: Neut_1039

Alternate gene names: 114331038

Gene position: 1076843-1077871 (Clockwise)

Preceding gene: 114331037

Following gene: 114331039

Centisome position: 40.47

GC content: 45.29

Gene sequence:

>1029_bases
ATGAATAAATACATGCAGATTTCGACTTCCGGATCAGCTCGCCGCTTGGCTGTTTTCATACTGATGATCTTGTTAATTGC
AGTGACTGCCATGCTGTGGAAATGGGCTGAAAAACAAGGGTACATCTCCGCAATGGAGCATTCCCTGGCAACATATCTGG
CTGATGCCGATGTTTTTAGCAGCCGTTCACGCACAATGCTTACCGAGCTTGAGCTTGAAAAAACAGAAATCGAGCAGCGC
TTAAATCATCTGGAAGAAAGATTGCTGGTTACCCGTGAATCGCCTGTTGAAGTTGGCAAGCTGTCTGACGGTGACAGTAC
TCATACGGGTGCCTGGATGCTGGGTGCGATCGAACGTCTTATTGTTTCGGCTGATCGTTATCTGCGGATGACGGGTGATG
TGCGTTCTGCACTTGACTCACTAAAATATGCGCAAGAACTGCTGCAATCCGATGAAATCCCTGGGTCATCAAAATTAAAT
GAGGCATTGGCAGGGGATATTGCGCAGCTTGAAGTGCTGGCTACTGTGGATGTCCAGAGGATTAACCGGGATATTACGGA
GCTTGCTACACGGATTGATGATCTTCCTTTGATGATGGACGCCAGTCTGATAGAGATTGATTTGCCGGAGAAACAAGATA
CATCCGAGCCACGGTTATGGCATCGTTATCTGCTTGAAATCGAAAAAGATCTCAGCCGGTTGATCAAAATTGAAAAAATA
AATGACTCGGGAACATCATTATTATCGCCTTCCCAGATTCATCTTCTAAAAGAAAATATCAGACTGCAATTGATGCAGGC
ACGCCTTGCCTTATTAATCCGAGATGAAGGCAATTTTCGCACTGCTGTGAAAACGGCAATAGATTGGGTGCAGCAGTATT
TTAATACAGAGGCTCAGTCAGTTAGAGATGCTCTGGGGGAGCTGGAAAGATTGGCCAGTATTAACATCGGATCACAGTTA
CCGAATTTGGGAGAAATCTTGGAAATTGTGTATCACGATCAACTCATGCTGAAAGGAGAGGGTGAATGA

Upstream 100 bases:

>100_bases
TCAGGAAGATATACCGCACTCCTCTCGGAGATGAAGGGACTGTGCAAGGTTTGTTGGAGTACTTCGAAAAAATACAGTCA
CACTGATAGCATCCGATCAT

Downstream 100 bases:

>100_bases
AACTGGTGTTATGGGTACTGGCATTATTCGCATCAGCGACAGCTATCGTATTGGCTGCGTACTACAACACGGGTTCGGTT
TTATTTACCGTACCTCCTTA

Product: protein of unknown function DUF513, hemX

Products: NA

Alternate protein names: Urogen-III methylase; ORF X [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MNKYMQISTSGSARRLAVFILMILLIAVTAMLWKWAEKQGYISAMEHSLATYLADADVFSSRSRTMLTELELEKTEIEQR
LNHLEERLLVTRESPVEVGKLSDGDSTHTGAWMLGAIERLIVSADRYLRMTGDVRSALDSLKYAQELLQSDEIPGSSKLN
EALAGDIAQLEVLATVDVQRINRDITELATRIDDLPLMMDASLIEIDLPEKQDTSEPRLWHRYLLEIEKDLSRLIKIEKI
NDSGTSLLSPSQIHLLKENIRLQLMQARLALLIRDEGNFRTAVKTAIDWVQQYFNTEAQSVRDALGELERLASINIGSQL
PNLGEILEIVYHDQLMLKGEGE

Sequences:

>Translated_342_residues
MNKYMQISTSGSARRLAVFILMILLIAVTAMLWKWAEKQGYISAMEHSLATYLADADVFSSRSRTMLTELELEKTEIEQR
LNHLEERLLVTRESPVEVGKLSDGDSTHTGAWMLGAIERLIVSADRYLRMTGDVRSALDSLKYAQELLQSDEIPGSSKLN
EALAGDIAQLEVLATVDVQRINRDITELATRIDDLPLMMDASLIEIDLPEKQDTSEPRLWHRYLLEIEKDLSRLIKIEKI
NDSGTSLLSPSQIHLLKENIRLQLMQARLALLIRDEGNFRTAVKTAIDWVQQYFNTEAQSVRDALGELERLASINIGSQL
PNLGEILEIVYHDQLMLKGEGE
>Mature_342_residues
MNKYMQISTSGSARRLAVFILMILLIAVTAMLWKWAEKQGYISAMEHSLATYLADADVFSSRSRTMLTELELEKTEIEQR
LNHLEERLLVTRESPVEVGKLSDGDSTHTGAWMLGAIERLIVSADRYLRMTGDVRSALDSLKYAQELLQSDEIPGSSKLN
EALAGDIAQLEVLATVDVQRINRDITELATRIDDLPLMMDASLIEIDLPEKQDTSEPRLWHRYLLEIEKDLSRLIKIEKI
NDSGTSLLSPSQIHLLKENIRLQLMQARLALLIRDEGNFRTAVKTAIDWVQQYFNTEAQSVRDALGELERLASINIGSQL
PNLGEILEIVYHDQLMLKGEGE

Specific function: Siroheme and cobalamin biosynthesis. [C]

COG id: COG2959

COG function: function code H; Uncharacterized enzyme of heme biosynthesis

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790235, Length=234, Percent_Identity=28.2051282051282, Blast_Score=72, Evalue=4e-14,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007470 [H]

Pfam domain/function: PF04375 HemX [H]

EC number: =2.1.1.107 [H]

Molecular weight: Translated: 38705; Mature: 38705

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKYMQISTSGSARRLAVFILMILLIAVTAMLWKWAEKQGYISAMEHSLATYLADADVFS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SRSRTMLTELELEKTEIEQRLNHLEERLLVTRESPVEVGKLSDGDSTHTGAWMLGAIERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IVSADRYLRMTGDVRSALDSLKYAQELLQSDEIPGSSKLNEALAGDIAQLEVLATVDVQR
HHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
INRDITELATRIDDLPLMMDASLIEIDLPEKQDTSEPRLWHRYLLEIEKDLSRLIKIEKI
HHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NDSGTSLLSPSQIHLLKENIRLQLMQARLALLIRDEGNFRTAVKTAIDWVQQYFNTEAQS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHH
VRDALGELERLASINIGSQLPNLGEILEIVYHDQLMLKGEGE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEECCCC
>Mature Secondary Structure
MNKYMQISTSGSARRLAVFILMILLIAVTAMLWKWAEKQGYISAMEHSLATYLADADVFS
CCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
SRSRTMLTELELEKTEIEQRLNHLEERLLVTRESPVEVGKLSDGDSTHTGAWMLGAIERL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
IVSADRYLRMTGDVRSALDSLKYAQELLQSDEIPGSSKLNEALAGDIAQLEVLATVDVQR
HHHHHHHHEECCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHH
INRDITELATRIDDLPLMMDASLIEIDLPEKQDTSEPRLWHRYLLEIEKDLSRLIKIEKI
HHHHHHHHHHHHCCCCHHCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NDSGTSLLSPSQIHLLKENIRLQLMQARLALLIRDEGNFRTAVKTAIDWVQQYFNTEAQS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCHHHH
VRDALGELERLASINIGSQLPNLGEILEIVYHDQLMLKGEGE
HHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3062586; 3054815; 1379743; 9278503; 9298646 [H]