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The map label for this gene is 114330995

Identifier: 114330995

GI number: 114330995

Start: 1024386

End: 1024958

Strand: Direct

Name: 114330995

Synonym: Neut_0993

Alternate gene names: NA

Gene position: 1024386-1024958 (Clockwise)

Preceding gene: 114330994

Following gene: 114330999

Centisome position: 38.5

GC content: 54.28

Gene sequence:

>573_bases
ATGAATCTGGTTTCATCTCTTGATATTGATTTTTCAGCTCCCTCTGCTGAAGTGGCGCGTTCCCTGATAGGCGTGACGCT
TATGCTGAATGGTGTAGGTGGTCGGATTGTGGAGGTGGAGGCTTATGATCATGAGGATCCTGCCTCACATTGTTTTGGTG
GAATAACGCCGCGCAATCAGGTGATGTTCGGGCCACCGTGCCATGCGTATGTCTATCGCTCTTACGGCATACATTGGTGC
TTCAATATTGTGTGCTGTCCGCCAGGCCATGGTGCCGGGGTGCTGATCCGCGCACTGGAGCCGCTGGCAGGAGGATTGGA
TGTTATGCGGAAACGACGCGGGCTGGATAATGTACGTTTGCTCTGCGCAGGCCCCGGGCGGCTTTGTCAGGCGCTCGGAA
TTACTATGGCGCATAGTGGCATGCCGGTTGATATTCCTCCGTTTCAGCTTCTGCCGGCCACAACTCCGGTAACAGTTATT
ACCGGGCCGCGTATTGGTATCTCCAGGGCAAAAGAAATACCCTGGCGTTTTGGGTTGGCTGGGTCGCGCTTTCTAAGTCG
TCCATTTCGCTGA

Upstream 100 bases:

>100_bases
ACCGGGAAAGTGGTTAAACGTTATGCGCCAGTTGATAAGCCGGAATCTCTGGTTGGAGATATCGAACAGTTGCTCTAATT
TTATTGAATGTTTGTCGTGT

Downstream 100 bases:

>100_bases
ATTTCTGCAGAAGCGAGTAAGTCGAGTCCTTGTCAGTAAGGGCTGATGTGGTTTGTGATAACCCGGAAGCTGGAAGTGTG
TTTCTGAAATTATTGGCTTG

Product: 3-methyladenine DNA glycosylase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MNLVSSLDIDFSAPSAEVARSLIGVTLMLNGVGGRIVEVEAYDHEDPASHCFGGITPRNQVMFGPPCHAYVYRSYGIHWC
FNIVCCPPGHGAGVLIRALEPLAGGLDVMRKRRGLDNVRLLCAGPGRLCQALGITMAHSGMPVDIPPFQLLPATTPVTVI
TGPRIGISRAKEIPWRFGLAGSRFLSRPFR

Sequences:

>Translated_190_residues
MNLVSSLDIDFSAPSAEVARSLIGVTLMLNGVGGRIVEVEAYDHEDPASHCFGGITPRNQVMFGPPCHAYVYRSYGIHWC
FNIVCCPPGHGAGVLIRALEPLAGGLDVMRKRRGLDNVRLLCAGPGRLCQALGITMAHSGMPVDIPPFQLLPATTPVTVI
TGPRIGISRAKEIPWRFGLAGSRFLSRPFR
>Mature_190_residues
MNLVSSLDIDFSAPSAEVARSLIGVTLMLNGVGGRIVEVEAYDHEDPASHCFGGITPRNQVMFGPPCHAYVYRSYGIHWC
FNIVCCPPGHGAGVLIRALEPLAGGLDVMRKRRGLDNVRLLCAGPGRLCQALGITMAHSGMPVDIPPFQLLPATTPVTVI
TGPRIGISRAKEIPWRFGLAGSRFLSRPFR

Specific function: Unknown

COG id: COG2094

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA glycosylase MPG family [H]

Homologues:

Organism=Homo sapiens, GI62632769, Length=143, Percent_Identity=45.4545454545455, Blast_Score=92, Evalue=4e-19,
Organism=Homo sapiens, GI62632771, Length=143, Percent_Identity=45.4545454545455, Blast_Score=91, Evalue=4e-19,
Organism=Homo sapiens, GI62632765, Length=143, Percent_Identity=45.4545454545455, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011034
- InterPro:   IPR003180 [H]

Pfam domain/function: PF02245 Pur_DNA_glyco [H]

EC number: 3.2.2.21

Molecular weight: Translated: 20476; Mature: 20476

Theoretical pI: Translated: 8.70; Mature: 8.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
3.7 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLVSSLDIDFSAPSAEVARSLIGVTLMLNGVGGRIVEVEAYDHEDPASHCFGGITPRNQ
CCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHCCCCCCCCC
VMFGPPCHAYVYRSYGIHWCFNIVCCPPGHGAGVLIRALEPLAGGLDVMRKRRGLDNVRL
EEECCCCCEEEECCCCEEEEEEEEECCCCCCHHHHEEHHHHHCCCHHHHHHHCCCCCEEE
LCAGPGRLCQALGITMAHSGMPVDIPPFQLLPATTPVTVITGPRIGISRAKEIPWRFGLA
EEECCHHHHHHHCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHHCCCEEECCC
GSRFLSRPFR
CCHHHCCCCC
>Mature Secondary Structure
MNLVSSLDIDFSAPSAEVARSLIGVTLMLNGVGGRIVEVEAYDHEDPASHCFGGITPRNQ
CCCCCCCCCCCCCCHHHHHHHHHHHEEEEECCCCEEEEEEECCCCCCHHHHCCCCCCCCC
VMFGPPCHAYVYRSYGIHWCFNIVCCPPGHGAGVLIRALEPLAGGLDVMRKRRGLDNVRL
EEECCCCCEEEECCCCEEEEEEEEECCCCCCHHHHEEHHHHHCCCHHHHHHHCCCCCEEE
LCAGPGRLCQALGITMAHSGMPVDIPPFQLLPATTPVTVITGPRIGISRAKEIPWRFGLA
EEECCHHHHHHHCCEEECCCCCCCCCCCEEECCCCCEEEEECCCCCCCHHHCCCEEECCC
GSRFLSRPFR
CCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA