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The map label for this gene is nuoI

Identifier: 114330933

GI number: 114330933

Start: 956860

End: 957348

Strand: Direct

Name: nuoI

Synonym: Neut_0930

Alternate gene names: 114330933

Gene position: 956860-957348 (Clockwise)

Preceding gene: 114330932

Following gene: 114330934

Centisome position: 35.96

GC content: 43.76

Gene sequence:

>489_bases
ATGGAACGCATTAAACGGTTTTTAAAATCCTTTTTGCTATTTGAGTTGTTAAAGGGAATGAAAGTAACTGGACGCTATTT
GTTTGCGCCTAAGGTTACTGTACATTATCCGGAAGAGAAGACGCCGCAATCACCTCGTTTTAGAGGGTTACATGCTTTGC
GTCGTTATCCTAATGGTGAGGAGCGCTGTATAGCGTGTAAGTTATGTGAAGCAGTTTGTCCGGCGTTGGCGATCACTATT
GAGTCAGAACAACGTGATGATGGTACACGGCGTACCACACGTTACGATATTGATCTGATTAAGTGTATTTTTTGTGGTTT
TTGTGAAGAAGCTTGTCCAGTAGATGCAATTGTCGAGACACGTGTGCTTGAGTATCACGGCGAAGTTCGTGGCGATCTGA
CTTATACCAAAGAAATGCTGCTGGCTGTGGGTGACCGTTATGAAGAGCAGATAGCCAAAGACAGAGCAGCAGATGCTCCT
TATCGTTAA

Upstream 100 bases:

>100_bases
TAATCTGGATTGTTTTATTGGGCGCAGTAATGCAATTGCCTGAAGCTGCATTGCAAAGCTTTCCATTGAATCTTTGGTTC
TAGTCAAGAGGAATTTCAAA

Downstream 100 bases:

>100_bases
ACATTTAGATATAAATTTATGATTTTCCAGGATTTTGTTTTTTACAGTCTGGCTAGTGTGGTGATAATTTGTGCACTAGG
AGTAATTACATTACGTAACC

Product: NADH dehydrogenase subunit I

Products: NA

Alternate protein names: NADH dehydrogenase I subunit I; NDH-1 subunit I

Number of amino acids: Translated: 162; Mature: 162

Protein sequence:

>162_residues
MERIKRFLKSFLLFELLKGMKVTGRYLFAPKVTVHYPEEKTPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITI
ESEQRDDGTRRTTRYDIDLIKCIFCGFCEEACPVDAIVETRVLEYHGEVRGDLTYTKEMLLAVGDRYEEQIAKDRAADAP
YR

Sequences:

>Translated_162_residues
MERIKRFLKSFLLFELLKGMKVTGRYLFAPKVTVHYPEEKTPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITI
ESEQRDDGTRRTTRYDIDLIKCIFCGFCEEACPVDAIVETRVLEYHGEVRGDLTYTKEMLLAVGDRYEEQIAKDRAADAP
YR
>Mature_162_residues
MERIKRFLKSFLLFELLKGMKVTGRYLFAPKVTVHYPEEKTPQSPRFRGLHALRRYPNGEERCIACKLCEAVCPALAITI
ESEQRDDGTRRTTRYDIDLIKCIFCGFCEEACPVDAIVETRVLEYHGEVRGDLTYTKEMLLAVGDRYEEQIAKDRAADAP
YR

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1143

COG function: function code C; Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I)

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains

Homologues:

Organism=Homo sapiens, GI4505371, Length=157, Percent_Identity=61.1464968152866, Blast_Score=199, Evalue=1e-51,
Organism=Escherichia coli, GI1788617, Length=128, Percent_Identity=42.1875, Blast_Score=102, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17555194, Length=155, Percent_Identity=58.7096774193548, Blast_Score=188, Evalue=9e-49,
Organism=Drosophila melanogaster, GI17864306, Length=157, Percent_Identity=60.5095541401274, Blast_Score=199, Evalue=6e-52,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NUOI_NITEC (Q0AHJ2)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_747155.1
- ProteinModelPortal:   Q0AHJ2
- SMR:   Q0AHJ2
- STRING:   Q0AHJ2
- GeneID:   4271833
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0930
- NMPDR:   fig|335283.3.peg.1574
- eggNOG:   COG1143
- HOGENOM:   HBG724359
- OMA:   NKAADAP
- PhylomeDB:   Q0AHJ2
- ProtClustDB:   PRK05888
- BioCyc:   NEUT335283:NEUT_0930-MONOMER
- HAMAP:   MF_01351
- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012285
- InterPro:   IPR010226
- Gene3D:   G3DSA:1.10.1060.10
- TIGRFAMs:   TIGR01971

Pfam domain/function: PF00037 Fer4

EC number: =1.6.99.5

Molecular weight: Translated: 18745; Mature: 18745

Theoretical pI: Translated: 7.68; Mature: 7.68

Prosite motif: PS00198 4FE4S_FER_1; PS51379 4FE4S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
4.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIKRFLKSFLLFELLKGMKVTGRYLFAPKVTVHYPEEKTPQSPRFRGLHALRRYPNGE
CHHHHHHHHHHHHHHHHHCCHHCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
ERCIACKLCEAVCPALAITIESEQRDDGTRRTTRYDIDLIKCIFCGFCEEACPVDAIVET
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RVLEYHGEVRGDLTYTKEMLLAVGDRYEEQIAKDRAADAPYR
HHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MERIKRFLKSFLLFELLKGMKVTGRYLFAPKVTVHYPEEKTPQSPRFRGLHALRRYPNGE
CHHHHHHHHHHHHHHHHHCCHHCCEEEECCEEEEECCCCCCCCCCHHHHHHHHHCCCCCC
ERCIACKLCEAVCPALAITIESEQRDDGTRRTTRYDIDLIKCIFCGFCEEACPVDAIVET
HHHHHHHHHHHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
RVLEYHGEVRGDLTYTKEMLLAVGDRYEEQIAKDRAADAPYR
HHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA