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The map label for this gene is ppiD [H]

Identifier: 114330677

GI number: 114330677

Start: 670110

End: 672002

Strand: Direct

Name: ppiD [H]

Synonym: Neut_0662

Alternate gene names: 114330677

Gene position: 670110-672002 (Clockwise)

Preceding gene: 114330676

Following gene: 114330679

Centisome position: 25.18

GC content: 47.07

Gene sequence:

>1893_bases
GTGTTTGATTTTGTAAACCAAAAGAAGACGATAGTTCAGATCGTGCTTTTTATTGCCCTCTTGCCGTTCTTGTTCTGGGG
GCTGGAGTCGTATCAAGGCATGGGTAGTGCGAGTGATGTTGCATCTGTTGATGGTGAGGAAATCAGCCGCCAGGAATATG
AGCAGGCTTTACGTAATCAACAGGAAAATCTGCGTAATATGCTGGGGGAAAATTTTGATGCCAGTCTGCTGGACAGCCCG
CAGATGCGTATGGCTGTTCTGGAAAATCTGATCCAGCAGAAGCTGTTGCGTCATGAGGCCGGGCGAGTTGGGCTGGCCGT
ACTGGATTCCCGTCTGACTGCCGAAATTCAGAATATCGCTCTTTTCCACGAGGACGATAAATTTTCGTATGAGCGTTACC
GTGAATTGCTTCAGCGCCAGGGAATGTCTCCCGCAATGTTTGAAGCGAGGCTGGCGGGTGATCTTATGCGACAACAGCTG
CTGGAAGGTATTACCGGAAGTGTGATCGTCTCCAAAACTGTTGCGGACAGAATAGCCTCACTCAGTGAAACCAAGTACGA
GATTAATCGGGTGACAATCAATCCTGAGCAATATATTAATCAGGCTGAACCCGATGAGGCTGCTATTCAGTCATACTATG
ACAGTCATCGTCAGGATTTCACGTTACCAGAACGGGTTCGGATCGAATATGTTGTGCTTTCTTTGGAAGAATTAGCGAAG
CAGGAGCAGATTTCTGATGAGGAAATCAAAAAATATTTTGATGAGCATCAGGATGAGTTTGGTCGGGTCGAGGAACGGAG
AGCCAGTCATATATTGCTGACCGTTCCGGTTGATGCAACTGAAGAGCAAAAGGCAGCCATTAAGGCTAAGGCAGAACAAA
TTCTAGAACAAGTAAAGCAGGATCCGGACAAATTTCCAGAATTGGCTAAGGAGTTGTCAGAAGATCCGGGTTCGGCGAAA
GCAGGCGGAGATCTTGGTTTCTTTGCACGTGGCTTGATGGTCAAAGCCTTTGAGGATACGGCGTTTGAGATGCAGCTGGA
TGAAATACGCGGCCCGGTAGAAACTCCGTTTGGTTTTCACATTATCAGGCTGACCGCAGTGAAAGATGCGAATGTGGCTA
AATTTGATGAAGTCAAGGAAGGCATCAGACAAACGCTCCAGCGTCAGAAGGCTGCTGACAGATTTGGTGAGCTATCCGAA
GATTTCAGCAATATTGTTTATGAGCAGAGTGATACATTGCAACCTGTAGCGCAGATGTTTAATCTGTCTGTTCAGCAAAG
TGACTGGATTGATCGTAATTCGAAGGAGCCGTCAGTTATTGCCAATGAACGTATGCTTCAGGCGATATTTTCGGAGGGCG
CTATTCGTGACCATTACAATACCGAGGCGATTGAAGTGGCTCCTGATACCTTCGTTTCGGCCAGAGTACTTGAGCATCGT
CCCGCCAGTGTGCAATCAATCGGACTGGTCAAGGATAAGATTATCGAACTTCTAAAGCAGCAAATCGCAGCTGCAACCGC
CGAGGAAGAAGGCAAACAGAAGCTTGCCAAATTGCAGGCAGGAGAGACTGATGAATCCCTGGAATGGGGAGAGCCAGTGG
AAATTTCCTATACTCAGAAAAGAGGGAGTGATGAAGAGATGCTACACGCACTTTTTCAAACAGATGTGGAAAAACTCCCT
GCTTATACTGGAGTCAAGACCAAGAAGGGTGGTTTTGACCTGATCCGGATCAATCAGGTGAAAGTACCAGCTGCTGAAAG
TGGATCATCCCAATATACTATGCTCATCAATCAGTTGCAGCAGGTACACGGTCAGGAAGAATTAAACGCCTATCTTGCTG
GCCTCAGGCAACGCTACGAAGTAAAAATCAAGCCAGTTGAGGAGAATGACTGA

Upstream 100 bases:

>100_bases
ACTCCGCCATATCTTTACTTTGCGTAATGTCCGGTCATGATGATATAACATCTTTTCCTCCCCCTGTTTTTCCCTGTTTC
CTTTTTTTCGGGTATTCGCC

Downstream 100 bases:

>100_bases
TAAGAAGAGCAGTAGTAGCCTGCAGGCTACTACTGCTCATCAGTGTCCAGATTAAATGCGACGGTATTGAACCCGGCATC
AACATAGGTAATTTCGCCGG

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 630; Mature: 630

Protein sequence:

>630_residues
MFDFVNQKKTIVQIVLFIALLPFLFWGLESYQGMGSASDVASVDGEEISRQEYEQALRNQQENLRNMLGENFDASLLDSP
QMRMAVLENLIQQKLLRHEAGRVGLAVLDSRLTAEIQNIALFHEDDKFSYERYRELLQRQGMSPAMFEARLAGDLMRQQL
LEGITGSVIVSKTVADRIASLSETKYEINRVTINPEQYINQAEPDEAAIQSYYDSHRQDFTLPERVRIEYVVLSLEELAK
QEQISDEEIKKYFDEHQDEFGRVEERRASHILLTVPVDATEEQKAAIKAKAEQILEQVKQDPDKFPELAKELSEDPGSAK
AGGDLGFFARGLMVKAFEDTAFEMQLDEIRGPVETPFGFHIIRLTAVKDANVAKFDEVKEGIRQTLQRQKAADRFGELSE
DFSNIVYEQSDTLQPVAQMFNLSVQQSDWIDRNSKEPSVIANERMLQAIFSEGAIRDHYNTEAIEVAPDTFVSARVLEHR
PASVQSIGLVKDKIIELLKQQIAAATAEEEGKQKLAKLQAGETDESLEWGEPVEISYTQKRGSDEEMLHALFQTDVEKLP
AYTGVKTKKGGFDLIRINQVKVPAAESGSSQYTMLINQLQQVHGQEELNAYLAGLRQRYEVKIKPVEEND

Sequences:

>Translated_630_residues
MFDFVNQKKTIVQIVLFIALLPFLFWGLESYQGMGSASDVASVDGEEISRQEYEQALRNQQENLRNMLGENFDASLLDSP
QMRMAVLENLIQQKLLRHEAGRVGLAVLDSRLTAEIQNIALFHEDDKFSYERYRELLQRQGMSPAMFEARLAGDLMRQQL
LEGITGSVIVSKTVADRIASLSETKYEINRVTINPEQYINQAEPDEAAIQSYYDSHRQDFTLPERVRIEYVVLSLEELAK
QEQISDEEIKKYFDEHQDEFGRVEERRASHILLTVPVDATEEQKAAIKAKAEQILEQVKQDPDKFPELAKELSEDPGSAK
AGGDLGFFARGLMVKAFEDTAFEMQLDEIRGPVETPFGFHIIRLTAVKDANVAKFDEVKEGIRQTLQRQKAADRFGELSE
DFSNIVYEQSDTLQPVAQMFNLSVQQSDWIDRNSKEPSVIANERMLQAIFSEGAIRDHYNTEAIEVAPDTFVSARVLEHR
PASVQSIGLVKDKIIELLKQQIAAATAEEEGKQKLAKLQAGETDESLEWGEPVEISYTQKRGSDEEMLHALFQTDVEKLP
AYTGVKTKKGGFDLIRINQVKVPAAESGSSQYTMLINQLQQVHGQEELNAYLAGLRQRYEVKIKPVEEND
>Mature_630_residues
MFDFVNQKKTIVQIVLFIALLPFLFWGLESYQGMGSASDVASVDGEEISRQEYEQALRNQQENLRNMLGENFDASLLDSP
QMRMAVLENLIQQKLLRHEAGRVGLAVLDSRLTAEIQNIALFHEDDKFSYERYRELLQRQGMSPAMFEARLAGDLMRQQL
LEGITGSVIVSKTVADRIASLSETKYEINRVTINPEQYINQAEPDEAAIQSYYDSHRQDFTLPERVRIEYVVLSLEELAK
QEQISDEEIKKYFDEHQDEFGRVEERRASHILLTVPVDATEEQKAAIKAKAEQILEQVKQDPDKFPELAKELSEDPGSAK
AGGDLGFFARGLMVKAFEDTAFEMQLDEIRGPVETPFGFHIIRLTAVKDANVAKFDEVKEGIRQTLQRQKAADRFGELSE
DFSNIVYEQSDTLQPVAQMFNLSVQQSDWIDRNSKEPSVIANERMLQAIFSEGAIRDHYNTEAIEVAPDTFVSARVLEHR
PASVQSIGLVKDKIIELLKQQIAAATAEEEGKQKLAKLQAGETDESLEWGEPVEISYTQKRGSDEEMLHALFQTDVEKLP
AYTGVKTKKGGFDLIRINQVKVPAAESGSSQYTMLINQLQQVHGQEELNAYLAGLRQRYEVKIKPVEEND

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=630, Percent_Identity=25.5555555555556, Blast_Score=203, Evalue=2e-53,
Organism=Escherichia coli, GI1786238, Length=118, Percent_Identity=37.2881355932203, Blast_Score=73, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 71437; Mature: 71437

Theoretical pI: Translated: 4.50; Mature: 4.50

Prosite motif: PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDFVNQKKTIVQIVLFIALLPFLFWGLESYQGMGSASDVASVDGEEISRQEYEQALRNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHH
QENLRNMLGENFDASLLDSPQMRMAVLENLIQQKLLRHEAGRVGLAVLDSRLTAEIQNIA
HHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LFHEDDKFSYERYRELLQRQGMSPAMFEARLAGDLMRQQLLEGITGSVIVSKTVADRIAS
EEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSETKYEINRVTINPEQYINQAEPDEAAIQSYYDSHRQDFTLPERVRIEYVVLSLEELAK
HHHHHEEEEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QEQISDEEIKKYFDEHQDEFGRVEERRASHILLTVPVDATEEQKAAIKAKAEQILEQVKQ
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DPDKFPELAKELSEDPGSAKAGGDLGFFARGLMVKAFEDTAFEMQLDEIRGPVETPFGFH
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHEEHHHHCCCCCCCCCEE
IIRLTAVKDANVAKFDEVKEGIRQTLQRQKAADRFGELSEDFSNIVYEQSDTLQPVAQMF
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NLSVQQSDWIDRNSKEPSVIANERMLQAIFSEGAIRDHYNTEAIEVAPDTFVSARVLEHR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCC
PASVQSIGLVKDKIIELLKQQIAAATAEEEGKQKLAKLQAGETDESLEWGEPVEISYTQK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
RGSDEEMLHALFQTDVEKLPAYTGVKTKKGGFDLIRINQVKVPAAESGSSQYTMLINQLQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
QVHGQEELNAYLAGLRQRYEVKIKPVEEND
HHHCHHHHHHHHHHHHHHCEEEEECCCCCC
>Mature Secondary Structure
MFDFVNQKKTIVQIVLFIALLPFLFWGLESYQGMGSASDVASVDGEEISRQEYEQALRNQ
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHHHHHHHHHHHHHHH
QENLRNMLGENFDASLLDSPQMRMAVLENLIQQKLLRHEAGRVGLAVLDSRLTAEIQNIA
HHHHHHHHCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LFHEDDKFSYERYRELLQRQGMSPAMFEARLAGDLMRQQLLEGITGSVIVSKTVADRIAS
EEECCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
LSETKYEINRVTINPEQYINQAEPDEAAIQSYYDSHRQDFTLPERVRIEYVVLSLEELAK
HHHHHEEEEEEEECHHHHCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHH
QEQISDEEIKKYFDEHQDEFGRVEERRASHILLTVPVDATEEQKAAIKAKAEQILEQVKQ
HHCCCHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHH
DPDKFPELAKELSEDPGSAKAGGDLGFFARGLMVKAFEDTAFEMQLDEIRGPVETPFGFH
CHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCHHHHEEHHHHCCCCCCCCCEE
IIRLTAVKDANVAKFDEVKEGIRQTLQRQKAADRFGELSEDFSNIVYEQSDTLQPVAQMF
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NLSVQQSDWIDRNSKEPSVIANERMLQAIFSEGAIRDHYNTEAIEVAPDTFVSARVLEHR
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCHHHHHHHHHCC
PASVQSIGLVKDKIIELLKQQIAAATAEEEGKQKLAKLQAGETDESLEWGEPVEISYTQK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCC
RGSDEEMLHALFQTDVEKLPAYTGVKTKKGGFDLIRINQVKVPAAESGSSQYTMLINQLQ
CCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCCCCCCCCHHHHHHHHHH
QVHGQEELNAYLAGLRQRYEVKIKPVEEND
HHHCHHHHHHHHHHHHHHCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]