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The map label for this gene is hupB [H]

Identifier: 114330676

GI number: 114330676

Start: 669498

End: 669770

Strand: Direct

Name: hupB [H]

Synonym: Neut_0661

Alternate gene names: 114330676

Gene position: 669498-669770 (Clockwise)

Preceding gene: 114330675

Following gene: 114330677

Centisome position: 25.16

GC content: 49.08

Gene sequence:

>273_bases
ATGAATAAATCTGAACTCATCGAAGCGATTGCTCGTCATGCCGATATTACAAAAGCAGAGGCGGGTAATGCACTGGATGG
TGCGTTATCTGCCATTAAGGATGCGCTTAGCAAGAATGACAGCGTCACCCTGGTAGGTTTTGGAACTTTCAAGGTTGGGG
AACGGGCTGCCCGTACGGGACGTAATCCGCGTACCGGTGCCGAGATAAAAATCAAGGCAGCTAAAGTGCCCAAATTCACT
GCTGGCAAAGCGCTGAAAGATGCTGTAAACTAG

Upstream 100 bases:

>100_bases
GACCGCCGCAAAACGGCTTGATATAAGGGTTTATACAGAGTTGTCTGTGTAAAAAGAGGTGTTTTCCTGCAACCTAACGA
AGCAAAACAAAGGGGAATTT

Downstream 100 bases:

>100_bases
CGCTCCTTCGATAGCAAAGAAAAGATGGGTGGGTTCGGGTGCTTAGCTCAGCTGGTAGAGCGTCGCCCTTACAAGGCGAA
TGTCGGCGGTTCGATCCCGT

Product: histone family protein DNA-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 90; Mature: 90

Protein sequence:

>90_residues
MNKSELIEAIARHADITKAEAGNALDGALSAIKDALSKNDSVTLVGFGTFKVGERAARTGRNPRTGAEIKIKAAKVPKFT
AGKALKDAVN

Sequences:

>Translated_90_residues
MNKSELIEAIARHADITKAEAGNALDGALSAIKDALSKNDSVTLVGFGTFKVGERAARTGRNPRTGAEIKIKAAKVPKFT
AGKALKDAVN
>Mature_90_residues
MNKSELIEAIARHADITKAEAGNALDGALSAIKDALSKNDSVTLVGFGTFKVGERAARTGRNPRTGAEIKIKAAKVPKFT
AGKALKDAVN

Specific function: Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions [H]

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family [H]

Homologues:

Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=66.6666666666667, Blast_Score=117, Evalue=2e-28,
Organism=Escherichia coli, GI1790433, Length=89, Percent_Identity=60.6741573033708, Blast_Score=110, Evalue=2e-26,
Organism=Escherichia coli, GI1787141, Length=91, Percent_Identity=37.3626373626374, Blast_Score=69, Evalue=4e-14,

Paralogues:

None

Copy number: 860 Molecules/Cell In: Growth-Phase, Minimal Media (Based on E. coli). 2040 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992 [H]

Pfam domain/function: PF00216 Bac_DNA_binding [H]

EC number: NA

Molecular weight: Translated: 9378; Mature: 9378

Theoretical pI: Translated: 10.71; Mature: 10.71

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKSELIEAIARHADITKAEAGNALDGALSAIKDALSKNDSVTLVGFGTFKVGERAARTG
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCC
RNPRTGAEIKIKAAKVPKFTAGKALKDAVN
CCCCCCCEEEEEECCCCCCCCCHHHHHHCC
>Mature Secondary Structure
MNKSELIEAIARHADITKAEAGNALDGALSAIKDALSKNDSVTLVGFGTFKVGERAARTG
CCHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHCC
RNPRTGAEIKIKAAKVPKFTAGKALKDAVN
CCCCCCCEEEEEECCCCCCCCCHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7867950; 10984043; 6793399 [H]