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The map label for this gene is gpsA

Identifier: 114330675

GI number: 114330675

Start: 668322

End: 669311

Strand: Direct

Name: gpsA

Synonym: Neut_0660

Alternate gene names: 114330675

Gene position: 668322-669311 (Clockwise)

Preceding gene: 114330674

Following gene: 114330676

Centisome position: 25.11

GC content: 51.31

Gene sequence:

>990_bases
ATGAATATCACGGTGCTTGGCGCGGGAGCCTGGGGAACTGCGCTGGCAATTTATCTGTCGGCACGTCATCACGTAACGTT
ATGGACCCGTAATACAGGGCACTTGGCAGAATTGGCGGCGTTGCGCGTCAATCAGCGTTATCTGCCGGGGCAGCATTTGC
CGGATTCCATCCATCTCGCTTCTGCGCTGAGTGATGCGTTGGAGCAGGCGGAGCTGGTTCTTGTGGTTGTGCCTGTTGCA
GGGTTGCGCGTAACTTTGCAGCGGATAGCTGCTTTGAATCAGTCATTGCCGCTTGTTCTGGGATGCAAGGGATTTGAGGC
AGGCACTGCAAAGCTTCCCTGCCAAGTGGTTGAGGATGTTTATTCGGCGGAGATCACTTGTGGCGTATTGTCTGGCCCAA
GTTTTGCCCAAGAGGTGGCAATGGGGCTTCCTGCTGCACTGACGCTGGCTTCTGATGATGATGCTTTTGCTAGACGGATT
GCCAGTGAGATTCATACTTCAATTTTACGTGTTTATTCCAGCAGTGATGTGGTTGGAGTTGAAGTTGGCGGGGCGCTCAA
GAATGTAATTGCAATTGCTGCCGGGATTTCTGACGGACTTGCGTTTGGTAATAATGCAAGAGCAGCACTGATTACTCGCG
GGCTGGCGGAAATTACCCGGCTGGGTGTGGCGCTGGGCGGGCATAGGAAAACCTTTACCGGTTTGAGTGGAATTGGAGAT
CTGATTTTGACTTGTACCGGTGATTTGTCAAGGAACCGTCAGGTTGGGATGATGCTTGCTGCCGGGTGTCAACTGCCAGA
GATTTTACTTGAAATCGGACATGTTACTGAAGGTGTGTATACCGTTCGAGAGGCGCACGAAATGGGACGGCAGCTACAAA
TTGATATGCCCGTAACTCAAGCGGTTTACAGTATTTTGTACGAACAAATCCCGGTTGAGAGTGCAATCAGGAATATGCTT
GATCGTGAACCTGGCGCAGAAACAGATTGA

Upstream 100 bases:

>100_bases
TGGTGCTGGAATGGCTGGGTGCTGCCGCAAATGGGTGGGTAAAAGTAAAACATCAGGATGGCCAGGTCGGCTATATCAGA
ACTGATCAAGTCTGGGGTGT

Downstream 100 bases:

>100_bases
GAGCAGATTTTACTGATGTGATACTTTCTCGATTCGGGTGAAACGGGAATTTATCAAAAATGAAGCTGATTTCTGGTTAA
ACACTTGACCGCCGCAAAAC

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Number of amino acids: Translated: 329; Mature: 329

Protein sequence:

>329_residues
MNITVLGAGAWGTALAIYLSARHHVTLWTRNTGHLAELAALRVNQRYLPGQHLPDSIHLASALSDALEQAELVLVVVPVA
GLRVTLQRIAALNQSLPLVLGCKGFEAGTAKLPCQVVEDVYSAEITCGVLSGPSFAQEVAMGLPAALTLASDDDAFARRI
ASEIHTSILRVYSSSDVVGVEVGGALKNVIAIAAGISDGLAFGNNARAALITRGLAEITRLGVALGGHRKTFTGLSGIGD
LILTCTGDLSRNRQVGMMLAAGCQLPEILLEIGHVTEGVYTVREAHEMGRQLQIDMPVTQAVYSILYEQIPVESAIRNML
DREPGAETD

Sequences:

>Translated_329_residues
MNITVLGAGAWGTALAIYLSARHHVTLWTRNTGHLAELAALRVNQRYLPGQHLPDSIHLASALSDALEQAELVLVVVPVA
GLRVTLQRIAALNQSLPLVLGCKGFEAGTAKLPCQVVEDVYSAEITCGVLSGPSFAQEVAMGLPAALTLASDDDAFARRI
ASEIHTSILRVYSSSDVVGVEVGGALKNVIAIAAGISDGLAFGNNARAALITRGLAEITRLGVALGGHRKTFTGLSGIGD
LILTCTGDLSRNRQVGMMLAAGCQLPEILLEIGHVTEGVYTVREAHEMGRQLQIDMPVTQAVYSILYEQIPVESAIRNML
DREPGAETD
>Mature_329_residues
MNITVLGAGAWGTALAIYLSARHHVTLWTRNTGHLAELAALRVNQRYLPGQHLPDSIHLASALSDALEQAELVLVVVPVA
GLRVTLQRIAALNQSLPLVLGCKGFEAGTAKLPCQVVEDVYSAEITCGVLSGPSFAQEVAMGLPAALTLASDDDAFARRI
ASEIHTSILRVYSSSDVVGVEVGGALKNVIAIAAGISDGLAFGNNARAALITRGLAEITRLGVALGGHRKTFTGLSGIGD
LILTCTGDLSRNRQVGMMLAAGCQLPEILLEIGHVTEGVYTVREAHEMGRQLQIDMPVTQAVYSILYEQIPVESAIRNML
DREPGAETD

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family

Homologues:

Organism=Homo sapiens, GI24307999, Length=341, Percent_Identity=29.9120234604106, Blast_Score=112, Evalue=6e-25,
Organism=Homo sapiens, GI33695088, Length=335, Percent_Identity=29.5522388059701, Blast_Score=110, Evalue=2e-24,
Organism=Escherichia coli, GI1790037, Length=309, Percent_Identity=45.9546925566343, Blast_Score=264, Evalue=5e-72,
Organism=Caenorhabditis elegans, GI32564399, Length=349, Percent_Identity=30.6590257879656, Blast_Score=120, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI32564403, Length=358, Percent_Identity=30.1675977653631, Blast_Score=114, Evalue=8e-26,
Organism=Caenorhabditis elegans, GI193210136, Length=358, Percent_Identity=30.1675977653631, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17507425, Length=340, Percent_Identity=28.2352941176471, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI193210134, Length=344, Percent_Identity=27.3255813953488, Blast_Score=94, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6320181, Length=348, Percent_Identity=29.5977011494253, Blast_Score=126, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6324513, Length=348, Percent_Identity=29.0229885057471, Blast_Score=116, Evalue=5e-27,
Organism=Drosophila melanogaster, GI17136200, Length=334, Percent_Identity=28.7425149700599, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136204, Length=334, Percent_Identity=28.7425149700599, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI17136202, Length=334, Percent_Identity=28.7425149700599, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI22026922, Length=342, Percent_Identity=24.5614035087719, Blast_Score=98, Evalue=1e-20,
Organism=Drosophila melanogaster, GI281362270, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI45551945, Length=238, Percent_Identity=29.8319327731092, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24648969, Length=182, Percent_Identity=30.7692307692308, Blast_Score=77, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPDA_NITEC (Q0AIA0)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746897.1
- ProteinModelPortal:   Q0AIA0
- SMR:   Q0AIA0
- STRING:   Q0AIA0
- GeneID:   4273090
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0660
- eggNOG:   COG0240
- HOGENOM:   HBG586392
- OMA:   NVAKGIE
- PhylomeDB:   Q0AIA0
- ProtClustDB:   PRK00094
- BioCyc:   NEUT335283:NEUT_0660-MONOMER
- HAMAP:   MF_00394
- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- Gene3D:   G3DSA:1.10.1040.10
- PANTHER:   PTHR11728
- PIRSF:   PIRSF000114
- PRINTS:   PR00077

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N; SSF48179 6DGDH_C_like

EC number: =1.1.1.94

Molecular weight: Translated: 34733; Mature: 34733

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00957 NAD_G3PDH

Important sites: ACT_SITE 187-187 BINDING 103-103 BINDING 103-103 BINDING 136-136 BINDING 251-251 BINDING 277-277

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNITVLGAGAWGTALAIYLSARHHVTLWTRNTGHLAELAALRVNQRYLPGQHLPDSIHLA
CEEEEEECCCHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
SALSDALEQAELVLVVVPVAGLRVTLQRIAALNQSLPLVLGCKGFEAGTAKLPCQVVEDV
HHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHH
YSAEITCGVLSGPSFAQEVAMGLPAALTLASDDDAFARRIASEIHTSILRVYSSSDVVGV
HHCCEEEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EVGGALKNVIAIAAGISDGLAFGNNARAALITRGLAEITRLGVALGGHRKTFTGLSGIGD
ECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCC
LILTCTGDLSRNRQVGMMLAAGCQLPEILLEIGHVTEGVYTVREAHEMGRQLQIDMPVTQ
EEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
AVYSILYEQIPVESAIRNMLDREPGAETD
HHHHHHHHHCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNITVLGAGAWGTALAIYLSARHHVTLWTRNTGHLAELAALRVNQRYLPGQHLPDSIHLA
CEEEEEECCCHHHHHHHHEECCCEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCCHHHHH
SALSDALEQAELVLVVVPVAGLRVTLQRIAALNQSLPLVLGCKGFEAGTAKLPCQVVEDV
HHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCHHHHHHH
YSAEITCGVLSGPSFAQEVAMGLPAALTLASDDDAFARRIASEIHTSILRVYSSSDVVGV
HHCCEEEEEECCCHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCEEEE
EVGGALKNVIAIAAGISDGLAFGNNARAALITRGLAEITRLGVALGGHRKTFTGLSGIGD
ECCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCHHHHCC
LILTCTGDLSRNRQVGMMLAAGCQLPEILLEIGHVTEGVYTVREAHEMGRQLQIDMPVTQ
EEEEECCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCHHH
AVYSILYEQIPVESAIRNMLDREPGAETD
HHHHHHHHHCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA