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The map label for this gene is corA [H]

Identifier: 114330563

GI number: 114330563

Start: 570754

End: 571755

Strand: Direct

Name: corA [H]

Synonym: Neut_0545

Alternate gene names: 114330563

Gene position: 570754-571755 (Clockwise)

Preceding gene: 114330561

Following gene: 114330564

Centisome position: 21.45

GC content: 48.5

Gene sequence:

>1002_bases
ATGCCATTGGCGTGTATTTCACTGCTGCGTTATGGAAAAAATGGGGTGATTGAAGAGCAACGTGGGCTTGCAGCACACGA
TTGCCGGGCGCCTGCTGCCAGCGCAGCAGACGTTATCTGGTTGCATTTACAAGGTCTACCTGCTCCAGAGCAGTTGCAGG
CGTTGAGTGCAGTGTTTGGTTTGCATCCGCTTGCGCTAGAGGATGTATTCCATCGGGAGACCCGTTCCAAAATAGAAGCC
TACGAGGCGCAGCAGTTTGTTGTGCTCAATTACCTGCATCAGGACCAAACGGGTAAATTCAATACCGGCCTGGTGAGTAT
TTTTCTGGGAAAGAACTATCTCATCAGTATTAACGATGGTCCAGGTGATCTTTTCGAGCCTGTTCGGCGGCGTATTCGCA
ATACGGGCAAGCCGTGCGAGCATGGTGCCGATTATTTACTATATGCACTGGCGGATGTCATTGTTGATAGTGGATTTTCG
TTGCTTGAGGAACTCGGCGATCAGATTGAAGCGCTGGAAAATGAAATTCTCGACAACCCAGGTCACGAGGCGCGCAACAA
AATTCATTGCATCAAGCGTGAATTGGTTCAGGTGCGTCGCATCTGGTGGCCGCAACGTGAGGTTATTGCCGCACTTATGC
GCGATGATGGACATTTTCTGTCGGATATCACACGTCTTTACATGCGTGACTGTTACGATCACTGCGTGATTGTGATTGAC
TTTGTTGAAACCTATCGTGAGATGGCGTCTAATCTGCTTGATACTTATCTGTCCGCAGTGAGCCAGCGTATGAATGATGT
CATGAAGGCACTTACCATTATCGCCACAATTTTTTTACCCCTTATGTTTCTCACGGGTCTGTACGGTATGAACTTTGATA
CTGAAAGCCCGTGGAATCTGCCTGAGCTGCACTGGCGTTTTGGCTATTTTTACGTGCTCAGTGTAATGGCCGTTGTGGTT
ATTGGCATGCTGATTTATTTCCGGCGCAAGCGTTGGTTGTAA

Upstream 100 bases:

>100_bases
TCATCCACGCAAGCATCATGCTCGCGTGCGTAATTATCGTCCAGGTGCGTCCCCCGGTTCTTTGGAAGCTCTGCCGGCTG
CAGGGTCAGGGACGACACCG

Downstream 100 bases:

>100_bases
GAACCTGTTTATGATCTTGTAAAACTGCTGATAATAATGTTGGGGCATGAGAAAAAATTATCCGAGCGACATCAGTCGCG
AACAATTTGAAATTATCAAG

Product: magnesium and cobalt transport protein CorA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 333; Mature: 332

Protein sequence:

>333_residues
MPLACISLLRYGKNGVIEEQRGLAAHDCRAPAASAADVIWLHLQGLPAPEQLQALSAVFGLHPLALEDVFHRETRSKIEA
YEAQQFVVLNYLHQDQTGKFNTGLVSIFLGKNYLISINDGPGDLFEPVRRRIRNTGKPCEHGADYLLYALADVIVDSGFS
LLEELGDQIEALENEILDNPGHEARNKIHCIKRELVQVRRIWWPQREVIAALMRDDGHFLSDITRLYMRDCYDHCVIVID
FVETYREMASNLLDTYLSAVSQRMNDVMKALTIIATIFLPLMFLTGLYGMNFDTESPWNLPELHWRFGYFYVLSVMAVVV
IGMLIYFRRKRWL

Sequences:

>Translated_333_residues
MPLACISLLRYGKNGVIEEQRGLAAHDCRAPAASAADVIWLHLQGLPAPEQLQALSAVFGLHPLALEDVFHRETRSKIEA
YEAQQFVVLNYLHQDQTGKFNTGLVSIFLGKNYLISINDGPGDLFEPVRRRIRNTGKPCEHGADYLLYALADVIVDSGFS
LLEELGDQIEALENEILDNPGHEARNKIHCIKRELVQVRRIWWPQREVIAALMRDDGHFLSDITRLYMRDCYDHCVIVID
FVETYREMASNLLDTYLSAVSQRMNDVMKALTIIATIFLPLMFLTGLYGMNFDTESPWNLPELHWRFGYFYVLSVMAVVV
IGMLIYFRRKRWL
>Mature_332_residues
PLACISLLRYGKNGVIEEQRGLAAHDCRAPAASAADVIWLHLQGLPAPEQLQALSAVFGLHPLALEDVFHRETRSKIEAY
EAQQFVVLNYLHQDQTGKFNTGLVSIFLGKNYLISINDGPGDLFEPVRRRIRNTGKPCEHGADYLLYALADVIVDSGFSL
LEELGDQIEALENEILDNPGHEARNKIHCIKRELVQVRRIWWPQREVIAALMRDDGHFLSDITRLYMRDCYDHCVIVIDF
VETYREMASNLLDTYLSAVSQRMNDVMKALTIIATIFLPLMFLTGLYGMNFDTESPWNLPELHWRFGYFYVLSVMAVVVI
GMLIYFRRKRWL

Specific function: Mediates influx of magnesium ions [H]

COG id: COG0598

COG function: function code P; Mg2+ and Co2+ transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family [H]

Homologues:

Organism=Escherichia coli, GI1787604, Length=187, Percent_Identity=26.2032085561497, Blast_Score=80, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6321058, Length=353, Percent_Identity=20.3966005665722, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324442, Length=201, Percent_Identity=22.8855721393035, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004488
- InterPro:   IPR002523 [H]

Pfam domain/function: PF01544 CorA [H]

EC number: NA

Molecular weight: Translated: 38179; Mature: 38047

Theoretical pI: Translated: 5.96; Mature: 5.96

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLACISLLRYGKNGVIEEQRGLAAHDCRAPAASAADVIWLHLQGLPAPEQLQALSAVFG
CCHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHC
LHPLALEDVFHRETRSKIEAYEAQQFVVLNYLHQDQTGKFNTGLVSIFLGKNYLISINDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECC
PGDLFEPVRRRIRNTGKPCEHGADYLLYALADVIVDSGFSLLEELGDQIEALENEILDNP
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
GHEARNKIHCIKRELVQVRRIWWPQREVIAALMRDDGHFLSDITRLYMRDCYDHCVIVID
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVETYREMASNLLDTYLSAVSQRMNDVMKALTIIATIFLPLMFLTGLYGMNFDTESPWNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PELHWRFGYFYVLSVMAVVVIGMLIYFRRKRWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PLACISLLRYGKNGVIEEQRGLAAHDCRAPAASAADVIWLHLQGLPAPEQLQALSAVFG
CHHHHHHHHHCCCCCCHHHCCCCHHHCCCCCCCHHHHHEEEECCCCCHHHHHHHHHHHC
LHPLALEDVFHRETRSKIEAYEAQQFVVLNYLHQDQTGKFNTGLVSIFLGKNYLISINDG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEEECC
PGDLFEPVRRRIRNTGKPCEHGADYLLYALADVIVDSGFSLLEELGDQIEALENEILDNP
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCC
GHEARNKIHCIKRELVQVRRIWWPQREVIAALMRDDGHFLSDITRLYMRDCYDHCVIVID
CHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
FVETYREMASNLLDTYLSAVSQRMNDVMKALTIIATIFLPLMFLTGLYGMNFDTESPWNL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PELHWRFGYFYVLSVMAVVVIGMLIYFRRKRWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]