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The map label for this gene is metX

Identifier: 114330546

GI number: 114330546

Start: 551014

End: 552147

Strand: Reverse

Name: metX

Synonym: Neut_0528

Alternate gene names: 114330546

Gene position: 552147-551014 (Counterclockwise)

Preceding gene: 114330547

Following gene: 114330545

Centisome position: 20.75

GC content: 50.35

Gene sequence:

>1134_bases
ATGTTCATGCAAGATTCTGATTCTATCGGTATCGTCTCGGCGCGACGCGTACATTTTGACACCCCACTCAGCCTGAAAAG
CAGGGCTGTACTGGACAGCTATGAACTGGTCTATGAAACCTACGGAGAGTTGAACCCGGAGCGATCCAATGCAATTCTGG
TCTGTCACGCATTATCCGGCAACCACCATGTGGCTGGTGTTTACGCAGATAATCCCAAGAATACCGGATGGTGGAACAAC
ATGATCGGTCCAGGAAAACCGATTGATACCCGGAAATTCTTTGTCATCGGCATTAATAATCTGGGTGGCTGCCATGGTTC
TACCGGCCCCATCAGCATTAATAACAGAACCGGAAAACGCTACGGCCCGGATTTTCCGCTGGTCACAACAAGTGACTGGG
CAAAAACCTATGTGCGTTTTGCTGACCAGTTCGGTATTGATTGTTTTGCTGCCATCATTGGGGGCAGTCTTGGGGGCATG
TCGGCCATGCAACTGGCGCTTGATGCTCCGGAAAGAGTGCGCCATGTCGCGGTGATCGCCGCTTCTGCCAGATTAACGGC
ACAGAATATTGCTTTCAACGATGTGGCACGACAAGCGATTCTGACCGATCCGGATTTTCATGGCGGAGACTATTATTCCC
ATGGCACCCACCCGCGCAGAGGGCTTCGCCTGGCCCGTATGCTCGGTCATATCACCTATCTGTCGGATGATTCCATGGCC
AGCAAATTTGGCCGCGAACTGCGTAATGGCTCGCTTGCATTCAATTATGACGTGGAGTTTCAGATTGAATCCTACCTGCA
TTATCAGGGAGATAAATTTGCCGATCTGTTCGATGCCAACACTTATCTGTTGATGACAAAAGCGCTGGATTATTTTGATC
CGGCACAGGATTATGATGGCAACCTGAGTGCAGCGTTTGCGCGTGCACAAGCAGATTTCCTGGTACTCTCATTCACCTCT
GACTGGCGTTTTTCTCCGGAACGCTCACGCGAGATCGTCAAAGCACTGCTCGACAATAAACTGAATGTCAGCTATGCGGA
AATACCTTCCACATACGGGCACGACTCTTTTCTCATGCAGGATGACTACTACCACCAGCTGGTGCGCGCCTACATGGATA
ACATCTCTATCTAG

Upstream 100 bases:

>100_bases
GATACATCCACCTCCCTAAGGAATACTGAATTTTCAGTAATACAATTAGATACAATGAGCATTCATTTTTCACATCTACA
GTCAGTTTTATTATTTTCAG

Downstream 100 bases:

>100_bases
CAGAACCGGTTAACGGTTTCTTATTTGGACATGACAACAACTGAAATCAGCAGATCAGTCCTGACATTGCGGCCGGATTT
CGCCACTATCGCAGCCTGGA

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSGNHHVAGVYADNPKNTGWWNN
MIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKRYGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGM
SAMQLALDAPERVRHVAVIAASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMA
SKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDGNLSAAFARAQADFLVLSFTS
DWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQDDYYHQLVRAYMDNISI

Sequences:

>Translated_377_residues
MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSGNHHVAGVYADNPKNTGWWNN
MIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKRYGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGM
SAMQLALDAPERVRHVAVIAASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMA
SKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDGNLSAAFARAQADFLVLSFTS
DWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQDDYYHQLVRAYMDNISI
>Mature_377_residues
MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSGNHHVAGVYADNPKNTGWWNN
MIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKRYGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGM
SAMQLALDAPERVRHVAVIAASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMA
SKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDGNLSAAFARAQADFLVLSFTS
DWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQDDYYHQLVRAYMDNISI

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=246, Percent_Identity=34.9593495934959, Blast_Score=160, Evalue=3e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): METX_NITEC (Q0AIM3)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746768.1
- ProteinModelPortal:   Q0AIM3
- SMR:   Q0AIM3
- STRING:   Q0AIM3
- GeneID:   4273794
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0528
- NMPDR:   fig|335283.3.peg.1405
- eggNOG:   COG2021
- HOGENOM:   HBG692920
- OMA:   VSFTSDW
- PhylomeDB:   Q0AIM3
- ProtClustDB:   PRK00175
- BioCyc:   NEUT335283:NEUT_0528-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00296
- InterPro:   IPR000073
- InterPro:   IPR008220
- PIRSF:   PIRSF000443
- TIGRFAMs:   TIGR01392

Pfam domain/function: PF00561 Abhydrolase_1

EC number: =2.3.1.31

Molecular weight: Translated: 42130; Mature: 42130

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: ACT_SITE 156-156 ACT_SITE 354-354

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSG
CCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
NHHVAGVYADNPKNTGWWNNMIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKR
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCC
YGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGMSAMQLALDAPERVRHVAVIA
CCCCCCEEECCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEEEE
ASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMA
ECCCEEHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCHHH
SKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDG
HHHHHHHCCCCEEEEEEEEEEEEEEEECCCCCHHHHHCCCEEEEEEHHHHHCCCCCCCCC
NLSAAFARAQADFLVLSFTSDWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQ
CHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEC
DDYYHQLVRAYMDNISI
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MFMQDSDSIGIVSARRVHFDTPLSLKSRAVLDSYELVYETYGELNPERSNAILVCHALSG
CCCCCCCCEEEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECC
NHHVAGVYADNPKNTGWWNNMIGPGKPIDTRKFFVIGINNLGGCHGSTGPISINNRTGKR
CEEEEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCEEECCCCCCC
YGPDFPLVTTSDWAKTYVRFADQFGIDCFAAIIGGSLGGMSAMQLALDAPERVRHVAVIA
CCCCCCEEECCHHHHHHHHHHHHHCHHHHHHHHCCCCCCHHHHHHHHCCHHHHHEEEEEE
ASARLTAQNIAFNDVARQAILTDPDFHGGDYYSHGTHPRRGLRLARMLGHITYLSDDSMA
ECCCEEHHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHEEECCCHHH
SKFGRELRNGSLAFNYDVEFQIESYLHYQGDKFADLFDANTYLLMTKALDYFDPAQDYDG
HHHHHHHCCCCEEEEEEEEEEEEEEEECCCCCHHHHHCCCEEEEEEHHHHHCCCCCCCCC
NLSAAFARAQADFLVLSFTSDWRFSPERSREIVKALLDNKLNVSYAEIPSTYGHDSFLMQ
CHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCHHHCCCCCCCCCEEEC
DDYYHQLVRAYMDNISI
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA