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The map label for this gene is dfrA [H]

Identifier: 114330479

GI number: 114330479

Start: 473782

End: 474705

Strand: Direct

Name: dfrA [H]

Synonym: Neut_0459

Alternate gene names: 114330479

Gene position: 473782-474705 (Clockwise)

Preceding gene: 114330478

Following gene: 114330480

Centisome position: 17.8

GC content: 43.51

Gene sequence:

>924_bases
ATGGTTAGAACTGTTGCAGTAACAGGTGCTACAGGATTTATTGGCCGCATACTTATTGCTAAGTTGGCTGAATCTGGATG
GAAAATCCGTGCATTGGCAAGATGTATATCTTCACAAAAAGATAGTCCATTCATAGAGTGGATTTCTGGAGATCTTGGTT
GTAATAATGCGTTGCGTGACCTTGTTTCTGGCGCTGAAGCTGTTATACATTGTGCCGGTGTAGTCAAAGGAAAATCTTGG
GATGATTTCTACCAGACCAATGTAATTGGAACGAGAAATATATTACGGGTAGCTTCTGACTCAACTTCTTGCTCAAGATT
TTTACACATTTCTTCTCTGGCAGCGCGTGAACCACTTCTTTCCTGGTATGCACGAAGCAAATTTGAGGCCGAAGAACAAA
TCCCGAGATTTTCTGGACGGTTAGCATCTGTTATATACAGGCCAGCTGCAGTTTACGGCCCTGGTGACAAAGCGATGCTA
CCTTTTTTTCGATCTATGCGATACGGTATACTCCCTGTTCCTGGAAATCCGGATAATCGTTTCGGCTTGATACATGTTGA
TGATTTGGTTGCTGCTATTTATTGCTGGCTTGAGACAACCCGTCCCGTGGGCGGTATTTATGCAATTGATGACGGCACAT
CAGATGGGTACAACTATACATCGATAGCCATGATTGCACAGCAAGTTCTAGGGAAGCCGGTACGTTGTTTCCAGATACCG
GCAAGCAGTATATGTATGTTGGCTCGTTTTAATTTGTGGTTGGCTCATCTTTTGAATTACGCTCCAATGCTGACACCAGG
AAAGGTGATGGAACTTCAGCATTCTGACTGGACCTGTGATATTTCTTTCCTGAGGAAAGAGCTAGTTGGTTGGCATCCGA
CAATCAAGTTACAAACAGCCTTGCCATCACTTGTCAAAATGTAA

Upstream 100 bases:

>100_bases
ACAGTCGGCTAATAGAATAGCTAATCCTTCATCAGTAAAATCTGCTTATTTCTTTAGGGGAAGGAGTCAAAAGATTTCTT
CTCGCATCCGGTAGTACTTT

Downstream 100 bases:

>100_bases
CAATATTTATTCCTGAAGCATTCGAAAATACTTCATGCGACAATACGCGACTTTCATGTTTCTCGATCCGGAAATAAATT
TGTTCATATACACTGTTCCG

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MVRTVAVTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLGCNNALRDLVSGAEAVIHCAGVVKGKSW
DDFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAREPLLSWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAML
PFFRSMRYGILPVPGNPDNRFGLIHVDDLVAAIYCWLETTRPVGGIYAIDDGTSDGYNYTSIAMIAQQVLGKPVRCFQIP
ASSICMLARFNLWLAHLLNYAPMLTPGKVMELQHSDWTCDISFLRKELVGWHPTIKLQTALPSLVKM

Sequences:

>Translated_307_residues
MVRTVAVTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLGCNNALRDLVSGAEAVIHCAGVVKGKSW
DDFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAREPLLSWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAML
PFFRSMRYGILPVPGNPDNRFGLIHVDDLVAAIYCWLETTRPVGGIYAIDDGTSDGYNYTSIAMIAQQVLGKPVRCFQIP
ASSICMLARFNLWLAHLLNYAPMLTPGKVMELQHSDWTCDISFLRKELVGWHPTIKLQTALPSLVKM
>Mature_307_residues
MVRTVAVTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLGCNNALRDLVSGAEAVIHCAGVVKGKSW
DDFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAREPLLSWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAML
PFFRSMRYGILPVPGNPDNRFGLIHVDDLVAAIYCWLETTRPVGGIYAIDDGTSDGYNYTSIAMIAQQVLGKPVRCFQIP
ASSICMLARFNLWLAHLLNYAPMLTPGKVMELQHSDWTCDISFLRKELVGWHPTIKLQTALPSLVKM

Specific function: Unknown

COG id: COG0702

COG function: function code MG; Predicted nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 33948; Mature: 33948

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRTVAVTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLGCNNALRD
CCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHH
LVSGAEAVIHCAGVVKGKSWDDFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAREPLL
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHH
SWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAMLPFFRSMRYGILPVPGNPDNR
HHHHHCCCCHHHHCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEEECCCCCCCC
FGLIHVDDLVAAIYCWLETTRPVGGIYAIDDGTSDGYNYTSIAMIAQQVLGKPVRCFQIP
EEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECC
ASSICMLARFNLWLAHLLNYAPMLTPGKVMELQHSDWTCDISFLRKELVGWHPTIKLQTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEEHHH
LPSLVKM
HHHHHCC
>Mature Secondary Structure
MVRTVAVTGATGFIGRILIAKLAESGWKIRALARCISSQKDSPFIEWISGDLGCNNALRD
CCEEEEECCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHHHCCCCCCCHHHHH
LVSGAEAVIHCAGVVKGKSWDDFYQTNVIGTRNILRVASDSTSCSRFLHISSLAAREPLL
HHHHHHHHHHHHHHHCCCCCCHHHHHCCCCCHHHHEECCCCCHHHHHHHHHHHHHHHHHH
SWYARSKFEAEEQIPRFSGRLASVIYRPAAVYGPGDKAMLPFFRSMRYGILPVPGNPDNR
HHHHHCCCCHHHHCHHHHHHHHHHHHCCCEEECCCCCHHHHHHHHCCCCEEECCCCCCCC
FGLIHVDDLVAAIYCWLETTRPVGGIYAIDDGTSDGYNYTSIAMIAQQVLGKPVRCFQIP
EEEEEHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHCCCCEEEECC
ASSICMLARFNLWLAHLLNYAPMLTPGKVMELQHSDWTCDISFLRKELVGWHPTIKLQTA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEHHHHHHHHCCCCCCEEEHHH
LPSLVKM
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]