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The map label for this gene is glk [H]

Identifier: 114330447

GI number: 114330447

Start: 443032

End: 444039

Strand: Direct

Name: glk [H]

Synonym: Neut_0427

Alternate gene names: 114330447

Gene position: 443032-444039 (Clockwise)

Preceding gene: 114330444

Following gene: 114330448

Centisome position: 16.65

GC content: 48.71

Gene sequence:

>1008_bases
ATGGATCAATATCTATTATATGGCGACATTGGTGGAACCAAAACCTTGTTGCGCTCTGCTGTGATCAAGAATGAGGAAGT
TGAGCTTCATTATGAGCATCGTTACGATAGTCGTCAGTACGGTGATTTTGACAGTATTCTGGAAGATTTCTTAAAGCAAT
CTGACTGTCAGCCGGTTGCTGTCTGTCTGGCAGTCGCCGGGCCGATTGTTGATCAACAGGTGCGCCTGACCAATTTGCCC
TGGACAATCAATGCCTCCGCCCTTGCGGAAAAATTTTCAATTTCTGCTGTGAAAATTGTCAATGATTTTGAGGGGATGGC
AGCTTCTATCGAAGTACTGCCGCAGGATGATCTGGTTATGCTGCAAGCCGGGGAACCTTCTTCTTCTGCGATGCGTGTTG
TACTGGGGGCGGGTACCGGGATGGGAGTTGCTTGGTTGATCAAGCGTGGACGATTTTACGAACCGCTTGCCACCGAAGCA
GGTCATGTTGATTTTGCACCGACCAGCGCCATTCAGATTGAATTGCTCAGATATCTGATGACAAAGTATCAGAGGGTTTC
AATTGAACGATTGCTTTCTGGTCAGGGATTGACTCACATTTTTAATTTTTTGCAAGCTGATGCGGCAGCTGGCGCTCACT
TGAAAAGTATTGAACTGGATGCTGATGATGGCGCAACCGTTACTCGGCTGGCTTTCGAGCACCAATATCCGATTGCTCTA
AAAGCGCTTGATCTGTTTGCCGAGATTTATGGTGCTTATGCAGGCAATCTGGCGCTGACAGGGTTATGCCGGGGTGGCGT
CTATATTGCAGGCGGCATCGCGCCGCGCATTATCCAAATTTTGCAACAACCCGGTTTTATCCAGGCATTCTGCAACAAAG
GGCGATACAGTGAACTGGTGCGCGAGATTCCGGTTTATGTGGTGATGAATCCGAAAGCTGGTTTGCTGGGTGCCGGGTTG
CTCGCACAGCGCATGCTGCATCAGTCAACGATATCTCTTGCGGAATAA

Upstream 100 bases:

>100_bases
TCTACTATGAGATTTCTGGCTTTTTTATGAGTCTGTGTTTCAATGGGGTTACATGTTTTAATGATCTTGTCATCATTATG
TGTCAGGAGGAAAGCAACTG

Downstream 100 bases:

>100_bases
CCGGGATTGGCTGAATGAGTAGTTATGAAAGCCTGATCGCAACACTGGCCTTGACCATGGGGAGTTCCTGGGCAAGCGGG
ATAAATCTGTATGCTGCGTT

Product: glucokinase

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MDQYLLYGDIGGTKTLLRSAVIKNEEVELHYEHRYDSRQYGDFDSILEDFLKQSDCQPVAVCLAVAGPIVDQQVRLTNLP
WTINASALAEKFSISAVKIVNDFEGMAASIEVLPQDDLVMLQAGEPSSSAMRVVLGAGTGMGVAWLIKRGRFYEPLATEA
GHVDFAPTSAIQIELLRYLMTKYQRVSIERLLSGQGLTHIFNFLQADAAAGAHLKSIELDADDGATVTRLAFEHQYPIAL
KALDLFAEIYGAYAGNLALTGLCRGGVYIAGGIAPRIIQILQQPGFIQAFCNKGRYSELVREIPVYVVMNPKAGLLGAGL
LAQRMLHQSTISLAE

Sequences:

>Translated_335_residues
MDQYLLYGDIGGTKTLLRSAVIKNEEVELHYEHRYDSRQYGDFDSILEDFLKQSDCQPVAVCLAVAGPIVDQQVRLTNLP
WTINASALAEKFSISAVKIVNDFEGMAASIEVLPQDDLVMLQAGEPSSSAMRVVLGAGTGMGVAWLIKRGRFYEPLATEA
GHVDFAPTSAIQIELLRYLMTKYQRVSIERLLSGQGLTHIFNFLQADAAAGAHLKSIELDADDGATVTRLAFEHQYPIAL
KALDLFAEIYGAYAGNLALTGLCRGGVYIAGGIAPRIIQILQQPGFIQAFCNKGRYSELVREIPVYVVMNPKAGLLGAGL
LAQRMLHQSTISLAE
>Mature_335_residues
MDQYLLYGDIGGTKTLLRSAVIKNEEVELHYEHRYDSRQYGDFDSILEDFLKQSDCQPVAVCLAVAGPIVDQQVRLTNLP
WTINASALAEKFSISAVKIVNDFEGMAASIEVLPQDDLVMLQAGEPSSSAMRVVLGAGTGMGVAWLIKRGRFYEPLATEA
GHVDFAPTSAIQIELLRYLMTKYQRVSIERLLSGQGLTHIFNFLQADAAAGAHLKSIELDADDGATVTRLAFEHQYPIAL
KALDLFAEIYGAYAGNLALTGLCRGGVYIAGGIAPRIIQILQQPGFIQAFCNKGRYSELVREIPVYVVMNPKAGLLGAGL
LAQRMLHQSTISLAE

Specific function: Not Highly Important In E.Coli As Glucose Is Transported Into The Cell By The Pts System Already As Glucose 6-Phosphate. [C]

COG id: COG0837

COG function: function code G; Glucokinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial glucokinase family [H]

Homologues:

Organism=Escherichia coli, GI1788732, Length=320, Percent_Identity=34.0625, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003836 [H]

Pfam domain/function: PF02685 Glucokinase [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 36540; Mature: 36540

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQYLLYGDIGGTKTLLRSAVIKNEEVELHYEHRYDSRQYGDFDSILEDFLKQSDCQPVA
CCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHH
VCLAVAGPIVDQQVRLTNLPWTINASALAEKFSISAVKIVNDFEGMAASIEVLPQDDLVM
HHHHHHCCCCCCCEEEECCCEEEEHHHHHHHHCCEEEEEEHHHCCCEEEEEEECCCCEEE
LQAGEPSSSAMRVVLGAGTGMGVAWLIKRGRFYEPLATEAGHVDFAPTSAIQIELLRYLM
EECCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TKYQRVSIERLLSGQGLTHIFNFLQADAAAGAHLKSIELDADDGATVTRLAFEHQYPIAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCHHH
KALDLFAEIYGAYAGNLALTGLCRGGVYIAGGIAPRIIQILQQPGFIQAFCNKGRYSELV
HHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHH
REIPVYVVMNPKAGLLGAGLLAQRMLHQSTISLAE
HHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDQYLLYGDIGGTKTLLRSAVIKNEEVELHYEHRYDSRQYGDFDSILEDFLKQSDCQPVA
CCCEEEEECCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCHHH
VCLAVAGPIVDQQVRLTNLPWTINASALAEKFSISAVKIVNDFEGMAASIEVLPQDDLVM
HHHHHHCCCCCCCEEEECCCEEEEHHHHHHHHCCEEEEEEHHHCCCEEEEEEECCCCEEE
LQAGEPSSSAMRVVLGAGTGMGVAWLIKRGRFYEPLATEAGHVDFAPTSAIQIELLRYLM
EECCCCCCCCEEEEEECCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
TKYQRVSIERLLSGQGLTHIFNFLQADAAAGAHLKSIELDADDGATVTRLAFEHQYPIAL
HHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEECCCCCHHH
KALDLFAEIYGAYAGNLALTGLCRGGVYIAGGIAPRIIQILQQPGFIQAFCNKGRYSELV
HHHHHHHHHHHHHCCCEEEEEEECCCEEEECCHHHHHHHHHHCCCHHHHHHCCCHHHHHH
REIPVYVVMNPKAGLLGAGLLAQRMLHQSTISLAE
HHCCEEEEECCCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA