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The map label for this gene is yciR [C]

Identifier: 114330442

GI number: 114330442

Start: 435042

End: 437417

Strand: Direct

Name: yciR [C]

Synonym: Neut_0422

Alternate gene names: 114330442

Gene position: 435042-437417 (Clockwise)

Preceding gene: 114330441

Following gene: 114330444

Centisome position: 16.35

GC content: 50.04

Gene sequence:

>2376_bases
GTGGCGCGCCAGTCAATTCTGATATCCGAGGGGCAACTGGTGCATGATTACCGTTTTTATCATCGAGACGGGCGGATCGT
CTGGTTGCTGGATCAATTGCAGCTAATTCGGGATGCCGGTGACCGACCATATGAAGTTGTCGGTACCTGTCTGGATATCA
GTGAACGAAAACGAACTGAACTGATCCGGCAAGCGCAGCAGTCAGCATTGGATCTGATTGTTACCAACCAGTCGCTTCCA
GTAATTTTGAGTGATATCGCGAAGCATCTCGAAGCGATCAATCCCGACATGCTGGTTTCCATTTTGTTGCTGGATAAGCA
AACAAAGCGCCTGAAGCTGGGAGCCGCACCCAGTTTGCCGGATGATTACAATGCGGCAGTCAACGGCCAGGAGATTGGTG
AAGGGGTAGGTTCCTGTGGTACGGCTGCCTTCCGGGGTGAAACGGTCATCGTGTCTGATATTGATCATCATCCGCACTGG
CAGCATTTTCTGGATTTGACACGCAAGGCTGATCTTCATGCTTGCTGGTCCCTGCCGTTCAAGGATGAGCACAATGATGT
GCTGGGTATTTTTGCCATCTATCATCATATCGCGTGCGAACCATCGCCAAAGGATCTGGAACTGATCCGGGAATTTGCGT
CCTTTACGGCGCTGGCCGTGCAAAAGGTTCGGGCAACAGAAGCTTTGCGACTTTCTGCCACGGTATTTGCATCCATCCGT
GAAGGGGTCGTGATTACAGATCTGGAGCCACGTATCGTTGCAGTCAATCGGGCATACATGAGGATAACTGGCTACAGTGA
GGAACAGGTGCTGGGCAAGAATCCCAAGATTATCAAATCAGGTCTCCACGACAAGACGTTTTACCAGGCAATGTGGGCTA
CCTTGAAGGCAACAGGGCACTGGAGTGGAGAGGTCTGGAATCGTCGCAAAAATGGTGAGATCTATCCACAATGGCTGACG
ATCAATGCGGTATGTATCGATTCATCCTGTTGTGATGAAAGCAATTCCTGTAATTATGTTGGTGTATTTACCGATATTTC
TCAAATAAAACAATCTGAAGCACAACTGGCACAACTGGCGCATTACGATCCGTTGACTGGTTTGCCCAACCGGCTGTTGG
CACAGTCACAGCTGCATCAAGCCATAGAGCGGGCGCAACGACATGGCCGGCTGGTTGGTGTGCTCTATATCGATCTTGAT
CGTTTCAAAAATGTTAACGATAGTCTGGGCCATCCAGTCGGAGATGAGCTGCTGATCAAACTGGCCGAGCGCATGAAGAA
GCGGGTACGTGAAGAAGATACACTGGCACGCCTGGGCGGGGATGAATTTTTGCTGGTGCTGGAAGATGTCCGTGATCTGG
GTGATCCAGCATTTGTTGCGCAAAGCCTGATCAATCTGCTTACTTCTCCGTTTGTGCTGCCTAGCGGGCATGAGATTTTT
ATTAATGCCAGTATCGGCATCAGTCTGTTCCCAGAGGATGCGAGCAATGCGACTGAGTTGATTCAGCATTCTGATATGGC
TATGTATCAGGCAAAAAAAGAGGGCCGCAATACCTATCGCTATCATACGGAAGCTTTGAGCGTTGCGGCGAATGAGCGGC
TGATTATGGAAAATCGTTTGCGTTACGCCCTCTCAGCTGAGGAGCTTATCTTGCATTATCAGCCGTTAGTAGATGCGCGT
ACCGGTTATGTGGTTGGGGTAGAAGCATTGGTGCGCTGGCAGCCGCCAGGAAAAGCCATGGTGCCACCAGGAAAATTTAT
ACCCATTGCAGAAGAAACGGGCCTGATCGTGCCGCTGGGAGAATGGGTGTTACGCACCGCCTGCAAGCAGGCTCGTGCCT
GGATTGATGCTGGTTTGTCCCCACTTGTTATGGCGGTTAACTTGTCGGTACGGCAATTCCAGTCAGAAAATCTGGTCGGC
ATGGTGCAGCGGATACTGGAAGAAACGCAGCTTCCGGCTGATTACCTGGAACTTGAATTGACCGAGAGCATGTTCATGGA
GCATGTGGAACAGTCGATTGAAACGTTGAACAAATTGAAGACGCTTGGAGTTCACCTGGCGATTGATGATTTTGGTACGG
GTTATTCATCATTGATTTATCTGAAGCGCTTTCCCATCGACAAGCTGAAAATTGATCAACGTTTTGTGCGTGATCTGGCG
GATGATCACAATGATCGCGAAATTGCTGCAACGATTATCGCCATGGCGCGTGGGCTAAAGCTGGGTGTCCTGGCAGAAGG
TATTGAATCAGAGGAGCAACTGGCTTTCCTGCGTCAGCAGGACTGTGATTATTATCAAGGATATCTGTTTCACCGGCCGG
TACCGGCAATAGAACTAGAAGCCTGGTTGCGTGAGCATTCGGTGCCCAATAGATAG

Upstream 100 bases:

>100_bases
GGCACACCGTGGGACTAAACAACTTGGCTATACCCCGGAAGAAGCATGTATTCCTGACTGGTGGATTTCACATTTACACC
CGGATGACCGGGATCAGGCA

Downstream 100 bases:

>100_bases
GCGTTACCGTAAATCTGGTTTTTCCGATATCCTCCATACTTTCTGCGATGAAAACAGATGAAGGATACGGAATCCTGATT
CCTCAATGGAATGGAGGTGC

Product: diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 791; Mature: 790

Protein sequence:

>791_residues
MARQSILISEGQLVHDYRFYHRDGRIVWLLDQLQLIRDAGDRPYEVVGTCLDISERKRTELIRQAQQSALDLIVTNQSLP
VILSDIAKHLEAINPDMLVSILLLDKQTKRLKLGAAPSLPDDYNAAVNGQEIGEGVGSCGTAAFRGETVIVSDIDHHPHW
QHFLDLTRKADLHACWSLPFKDEHNDVLGIFAIYHHIACEPSPKDLELIREFASFTALAVQKVRATEALRLSATVFASIR
EGVVITDLEPRIVAVNRAYMRITGYSEEQVLGKNPKIIKSGLHDKTFYQAMWATLKATGHWSGEVWNRRKNGEIYPQWLT
INAVCIDSSCCDESNSCNYVGVFTDISQIKQSEAQLAQLAHYDPLTGLPNRLLAQSQLHQAIERAQRHGRLVGVLYIDLD
RFKNVNDSLGHPVGDELLIKLAERMKKRVREEDTLARLGGDEFLLVLEDVRDLGDPAFVAQSLINLLTSPFVLPSGHEIF
INASIGISLFPEDASNATELIQHSDMAMYQAKKEGRNTYRYHTEALSVAANERLIMENRLRYALSAEELILHYQPLVDAR
TGYVVGVEALVRWQPPGKAMVPPGKFIPIAEETGLIVPLGEWVLRTACKQARAWIDAGLSPLVMAVNLSVRQFQSENLVG
MVQRILEETQLPADYLELELTESMFMEHVEQSIETLNKLKTLGVHLAIDDFGTGYSSLIYLKRFPIDKLKIDQRFVRDLA
DDHNDREIAATIIAMARGLKLGVLAEGIESEEQLAFLRQQDCDYYQGYLFHRPVPAIELEAWLREHSVPNR

Sequences:

>Translated_791_residues
MARQSILISEGQLVHDYRFYHRDGRIVWLLDQLQLIRDAGDRPYEVVGTCLDISERKRTELIRQAQQSALDLIVTNQSLP
VILSDIAKHLEAINPDMLVSILLLDKQTKRLKLGAAPSLPDDYNAAVNGQEIGEGVGSCGTAAFRGETVIVSDIDHHPHW
QHFLDLTRKADLHACWSLPFKDEHNDVLGIFAIYHHIACEPSPKDLELIREFASFTALAVQKVRATEALRLSATVFASIR
EGVVITDLEPRIVAVNRAYMRITGYSEEQVLGKNPKIIKSGLHDKTFYQAMWATLKATGHWSGEVWNRRKNGEIYPQWLT
INAVCIDSSCCDESNSCNYVGVFTDISQIKQSEAQLAQLAHYDPLTGLPNRLLAQSQLHQAIERAQRHGRLVGVLYIDLD
RFKNVNDSLGHPVGDELLIKLAERMKKRVREEDTLARLGGDEFLLVLEDVRDLGDPAFVAQSLINLLTSPFVLPSGHEIF
INASIGISLFPEDASNATELIQHSDMAMYQAKKEGRNTYRYHTEALSVAANERLIMENRLRYALSAEELILHYQPLVDAR
TGYVVGVEALVRWQPPGKAMVPPGKFIPIAEETGLIVPLGEWVLRTACKQARAWIDAGLSPLVMAVNLSVRQFQSENLVG
MVQRILEETQLPADYLELELTESMFMEHVEQSIETLNKLKTLGVHLAIDDFGTGYSSLIYLKRFPIDKLKIDQRFVRDLA
DDHNDREIAATIIAMARGLKLGVLAEGIESEEQLAFLRQQDCDYYQGYLFHRPVPAIELEAWLREHSVPNR
>Mature_790_residues
ARQSILISEGQLVHDYRFYHRDGRIVWLLDQLQLIRDAGDRPYEVVGTCLDISERKRTELIRQAQQSALDLIVTNQSLPV
ILSDIAKHLEAINPDMLVSILLLDKQTKRLKLGAAPSLPDDYNAAVNGQEIGEGVGSCGTAAFRGETVIVSDIDHHPHWQ
HFLDLTRKADLHACWSLPFKDEHNDVLGIFAIYHHIACEPSPKDLELIREFASFTALAVQKVRATEALRLSATVFASIRE
GVVITDLEPRIVAVNRAYMRITGYSEEQVLGKNPKIIKSGLHDKTFYQAMWATLKATGHWSGEVWNRRKNGEIYPQWLTI
NAVCIDSSCCDESNSCNYVGVFTDISQIKQSEAQLAQLAHYDPLTGLPNRLLAQSQLHQAIERAQRHGRLVGVLYIDLDR
FKNVNDSLGHPVGDELLIKLAERMKKRVREEDTLARLGGDEFLLVLEDVRDLGDPAFVAQSLINLLTSPFVLPSGHEIFI
NASIGISLFPEDASNATELIQHSDMAMYQAKKEGRNTYRYHTEALSVAANERLIMENRLRYALSAEELILHYQPLVDART
GYVVGVEALVRWQPPGKAMVPPGKFIPIAEETGLIVPLGEWVLRTACKQARAWIDAGLSPLVMAVNLSVRQFQSENLVGM
VQRILEETQLPADYLELELTESMFMEHVEQSIETLNKLKTLGVHLAIDDFGTGYSSLIYLKRFPIDKLKIDQRFVRDLAD
DHNDREIAATIIAMARGLKLGVLAEGIESEEQLAFLRQQDCDYYQGYLFHRPVPAIELEAWLREHSVPNR

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=562, Percent_Identity=35.0533807829181, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI87081921, Length=436, Percent_Identity=34.1743119266055, Blast_Score=258, Evalue=8e-70,
Organism=Escherichia coli, GI226510982, Length=427, Percent_Identity=29.9765807962529, Blast_Score=179, Evalue=8e-46,
Organism=Escherichia coli, GI87081845, Length=249, Percent_Identity=35.3413654618474, Blast_Score=152, Evalue=1e-37,
Organism=Escherichia coli, GI1790496, Length=249, Percent_Identity=32.1285140562249, Blast_Score=148, Evalue=2e-36,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=32.1285140562249, Blast_Score=146, Evalue=4e-36,
Organism=Escherichia coli, GI87081743, Length=249, Percent_Identity=33.7349397590361, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081980, Length=262, Percent_Identity=32.824427480916, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1787055, Length=460, Percent_Identity=26.5217391304348, Blast_Score=135, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=262, Percent_Identity=29.3893129770992, Blast_Score=129, Evalue=1e-30,
Organism=Escherichia coli, GI1788381, Length=520, Percent_Identity=25.7692307692308, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788849, Length=247, Percent_Identity=35.2226720647773, Blast_Score=125, Evalue=8e-30,
Organism=Escherichia coli, GI87082096, Length=425, Percent_Identity=27.0588235294118, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1786584, Length=175, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=35.3293413173653, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693134, Length=155, Percent_Identity=34.8387096774194, Blast_Score=90, Evalue=7e-19,
Organism=Escherichia coli, GI1787262, Length=165, Percent_Identity=34.5454545454545, Blast_Score=89, Evalue=7e-19,
Organism=Escherichia coli, GI87081977, Length=173, Percent_Identity=30.635838150289, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI87081881, Length=180, Percent_Identity=35.5555555555556, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI1787816, Length=159, Percent_Identity=30.8176100628931, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI87082007, Length=174, Percent_Identity=31.0344827586207, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87081974, Length=99, Percent_Identity=38.3838383838384, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1787802, Length=191, Percent_Identity=26.7015706806283, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787410, Length=235, Percent_Identity=24.2553191489362, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789650, Length=424, Percent_Identity=22.1698113207547, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788085, Length=177, Percent_Identity=28.2485875706215, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 89138; Mature: 89007

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARQSILISEGQLVHDYRFYHRDGRIVWLLDQLQLIRDAGDRPYEVVGTCLDISERKRTE
CCCCCEEECCCCEEEEEHEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHH
LIRQAQQSALDLIVTNQSLPVILSDIAKHLEAINPDMLVSILLLDKQTKRLKLGAAPSLP
HHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEECCCCCCC
DDYNAAVNGQEIGEGVGSCGTAAFRGETVIVSDIDHHPHWQHFLDLTRKADLHACWSLPF
CCCCCCCCHHHHHHCCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHCCCCHHEECCCC
KDEHNDVLGIFAIYHHIACEPSPKDLELIREFASFTALAVQKVRATEALRLSATVFASIR
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVVITDLEPRIVAVNRAYMRITGYSEEQVLGKNPKIIKSGLHDKTFYQAMWATLKATGH
CCEEEEECCCCEEEEEEEEEEEECCCHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
WSGEVWNRRKNGEIYPQWLTINAVCIDSSCCDESNSCNYVGVFTDISQIKQSEAQLAQLA
CCCHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
HYDPLTGLPNRLLAQSQLHQAIERAQRHGRLVGVLYIDLDRFKNVNDSLGHPVGDELLIK
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHCCCCCCHHHHHH
LAERMKKRVREEDTLARLGGDEFLLVLEDVRDLGDPAFVAQSLINLLTSPFVLPSGHEIF
HHHHHHHHHCHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEE
INASIGISLFPEDASNATELIQHSDMAMYQAKKEGRNTYRYHTEALSVAANERLIMENRL
EEEECCEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHH
RYALSAEELILHYQPLVDARTGYVVGVEALVRWQPPGKAMVPPGKFIPIAEETGLIVPLG
HHHHCHHHHHHHHHCHHCCCCCEEEEEEHHEEECCCCCCCCCCCCEEEEECCCCEEEEHH
EWVLRTACKQARAWIDAGLSPLVMAVNLSVRQFQSENLVGMVQRILEETQLPADYLELEL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
TESMFMEHVEQSIETLNKLKTLGVHLAIDDFGTGYSSLIYLKRFPIDKLKIDQRFVRDLA
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHEEEHCCCCCCHHHHHHHHHHHHH
DDHNDREIAATIIAMARGLKLGVLAEGIESEEQLAFLRQQDCDYYQGYLFHRPVPAIELE
CCCCCHHHHHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHHCCCHHCCEEEECCCCCHHHH
AWLREHSVPNR
HHHHHCCCCCC
>Mature Secondary Structure 
ARQSILISEGQLVHDYRFYHRDGRIVWLLDQLQLIRDAGDRPYEVVGTCLDISERKRTE
CCCCEEECCCCEEEEEHEEECCCCEEEEHHHHHHHHHCCCCCHHHHHHHHCHHHHHHHH
LIRQAQQSALDLIVTNQSLPVILSDIAKHLEAINPDMLVSILLLDKQTKRLKLGAAPSLP
HHHHHHHHHEEEEEECCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHEEECCCCCCC
DDYNAAVNGQEIGEGVGSCGTAAFRGETVIVSDIDHHPHWQHFLDLTRKADLHACWSLPF
CCCCCCCCHHHHHHCCCCCCCCEECCCEEEEECCCCCCCHHHHHHHHHCCCCHHEECCCC
KDEHNDVLGIFAIYHHIACEPSPKDLELIREFASFTALAVQKVRATEALRLSATVFASIR
CCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EGVVITDLEPRIVAVNRAYMRITGYSEEQVLGKNPKIIKSGLHDKTFYQAMWATLKATGH
CCEEEEECCCCEEEEEEEEEEEECCCHHHHCCCCCHHHHCCCCHHHHHHHHHHHHHHCCC
WSGEVWNRRKNGEIYPQWLTINAVCIDSSCCDESNSCNYVGVFTDISQIKQSEAQLAQLA
CCCHHHCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHHHH
HYDPLTGLPNRLLAQSQLHQAIERAQRHGRLVGVLYIDLDRFKNVNDSLGHPVGDELLIK
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHCCCCHHCCCCCCHHHHHH
LAERMKKRVREEDTLARLGGDEFLLVLEDVRDLGDPAFVAQSLINLLTSPFVLPSGHEIF
HHHHHHHHHCHHHHHHHCCCCCEEEEEHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEE
INASIGISLFPEDASNATELIQHSDMAMYQAKKEGRNTYRYHTEALSVAANERLIMENRL
EEEECCEEECCCCCCHHHHHHHHCCHHHHHHHHCCCCCCEEHHHHHHHHCCCHHHHHHHH
RYALSAEELILHYQPLVDARTGYVVGVEALVRWQPPGKAMVPPGKFIPIAEETGLIVPLG
HHHHCHHHHHHHHHCHHCCCCCEEEEEEHHEEECCCCCCCCCCCCEEEEECCCCEEEEHH
EWVLRTACKQARAWIDAGLSPLVMAVNLSVRQFQSENLVGMVQRILEETQLPADYLELEL
HHHHHHHHHHHHHHHHCCCCHHHHHHCCHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHH
TESMFMEHVEQSIETLNKLKTLGVHLAIDDFGTGYSSLIYLKRFPIDKLKIDQRFVRDLA
HHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCHHHEEEHCCCCCCHHHHHHHHHHHHH
DDHNDREIAATIIAMARGLKLGVLAEGIESEEQLAFLRQQDCDYYQGYLFHRPVPAIELE
CCCCCHHHHHHHHHHHCCCEEEHHHHCCCCHHHHHHHHHHCCCHHCCEEEECCCCCHHHH
AWLREHSVPNR
HHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]