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The map label for this gene is yggW [H]

Identifier: 114330337

GI number: 114330337

Start: 316666

End: 317901

Strand: Direct

Name: yggW [H]

Synonym: Neut_0310

Alternate gene names: 114330337

Gene position: 316666-317901 (Clockwise)

Preceding gene: 114330336

Following gene: 114330338

Centisome position: 11.9

GC content: 49.27

Gene sequence:

>1236_bases
ATGAAAAAAATAATCCCGGTTTTATCCCTGCCTGATTCAAAATCACCTCATCTGATTGAGCTTCCTCCCTTAGGGTTGTA
CATTCATCTGCCCTGGTGCGTCAGAAAATGTCCTTATTGTGATTTCAATTCGCATGCAATTGATCCGAATAGCGCGCTCC
CGGAGGCCGAATATGTTGCAGCACTCAAGCGTGATCTGGAGCTATCGTTGCCACAAATCTGGGGGCGGCCTGTTACCAGC
GTATTTTTGGGTGGCGGAACCCCGAGCCTGTTCAGTGGTGCCTCAATCGATGCAATTCTTTCGTATGCGCGTATGCTGCT
GTCTTTTGCTCCCGAGACTGAAATTACACTGGAAGCCAATCCGGGAACGCTGGAAGCACAAAAGTTTGCAGATTTCCGGT
CTGCTGGCATTAATCGACTGTCCATTGGTATCCAAAGTTTCAATCCCGGGCATTTGCAGGCATTGGGGCGTATCCATAAT
GATGCTGAAGCTTCTCGTGCGGTTGAACAGGCGCTACAGCATTTCAGCAATATCAATCTGGATTTAATGTATGCACTGCC
GAATCAAACCCAGGATGAAGCATTGCAGGACATTGAGGCAGCCTGTGGCTGGGGCGTACCGCATATCTCTGCTTATCACC
TGACGCTTGAACCCAATACCCTGTTTTATCGCCAGCCGCCAAAATTGCCAGATGAAGATACATCAGCTGATATGCAGATC
ATGATCGAGCGTGTTCTTGCAGAAAAAGGCTACCAGCACTACGAGACTTCTGCATTTGCACAGCCCGGGAGGATGTGTGT
GCATAATATGAACTACTGGCAATATGGCGATTATCTGGGGATCGGTGCCGGGGCGCACAGCAAAATCAGCTTTCGAGAAA
AAATTATCCGGCAGATGCGTCATAAGCACCCTCGTCACTATCTGGAGCAGGCCGCAGCTAGAAATACCAATCTTGAAAAT
ATGCTTGCCACGGAACAGGAAGTTGGGCCGCAAGACCGGATTTTTGAGTTCATGATGAATGCACTGCGATTGACGGACGG
TTTTGATCCTGGGCTGTTTCATACTCGTACTGGCTTGACAGTTGCCTCAATTCAGCAGCAACTAACCACTGCCGAGCAAC
GAGGGTTGATTGAGTGGCAGCACGATTGTATCCGGCCGACGGCTGACGGGCGAAGGTTTTTGAATGACTTGCTGGAGATT
TTTCTGCCAGAATCCAGGCAAACGACAACTTCCTGA

Upstream 100 bases:

>100_bases
CATCGCGGCAAGGCGCTTGCCAGGCTGGTACAAATACTGGCGGGGAATGAAAAAATGCCGGTTTAGTTTGACATAACGTG
TTTGTGATCATGCGATTGAC

Downstream 100 bases:

>100_bases
ACTTAAAATAGCGGGGGGGGGGGAGATCGGAATGAAGGACTCAATTTCAAGACGCGCCTTTCTGAAAAAATCAGGCACAC
TGGGAACCCTTACTGCTCTG

Product: coproporphyrinogen III oxidase

Products: Protoporphyrinogen IX; CO2; H2O

Alternate protein names: NA

Number of amino acids: Translated: 411; Mature: 411

Protein sequence:

>411_residues
MKKIIPVLSLPDSKSPHLIELPPLGLYIHLPWCVRKCPYCDFNSHAIDPNSALPEAEYVAALKRDLELSLPQIWGRPVTS
VFLGGGTPSLFSGASIDAILSYARMLLSFAPETEITLEANPGTLEAQKFADFRSAGINRLSIGIQSFNPGHLQALGRIHN
DAEASRAVEQALQHFSNINLDLMYALPNQTQDEALQDIEAACGWGVPHISAYHLTLEPNTLFYRQPPKLPDEDTSADMQI
MIERVLAEKGYQHYETSAFAQPGRMCVHNMNYWQYGDYLGIGAGAHSKISFREKIIRQMRHKHPRHYLEQAAARNTNLEN
MLATEQEVGPQDRIFEFMMNALRLTDGFDPGLFHTRTGLTVASIQQQLTTAEQRGLIEWQHDCIRPTADGRRFLNDLLEI
FLPESRQTTTS

Sequences:

>Translated_411_residues
MKKIIPVLSLPDSKSPHLIELPPLGLYIHLPWCVRKCPYCDFNSHAIDPNSALPEAEYVAALKRDLELSLPQIWGRPVTS
VFLGGGTPSLFSGASIDAILSYARMLLSFAPETEITLEANPGTLEAQKFADFRSAGINRLSIGIQSFNPGHLQALGRIHN
DAEASRAVEQALQHFSNINLDLMYALPNQTQDEALQDIEAACGWGVPHISAYHLTLEPNTLFYRQPPKLPDEDTSADMQI
MIERVLAEKGYQHYETSAFAQPGRMCVHNMNYWQYGDYLGIGAGAHSKISFREKIIRQMRHKHPRHYLEQAAARNTNLEN
MLATEQEVGPQDRIFEFMMNALRLTDGFDPGLFHTRTGLTVASIQQQLTTAEQRGLIEWQHDCIRPTADGRRFLNDLLEI
FLPESRQTTTS
>Mature_411_residues
MKKIIPVLSLPDSKSPHLIELPPLGLYIHLPWCVRKCPYCDFNSHAIDPNSALPEAEYVAALKRDLELSLPQIWGRPVTS
VFLGGGTPSLFSGASIDAILSYARMLLSFAPETEITLEANPGTLEAQKFADFRSAGINRLSIGIQSFNPGHLQALGRIHN
DAEASRAVEQALQHFSNINLDLMYALPNQTQDEALQDIEAACGWGVPHISAYHLTLEPNTLFYRQPPKLPDEDTSADMQI
MIERVLAEKGYQHYETSAFAQPGRMCVHNMNYWQYGDYLGIGAGAHSKISFREKIIRQMRHKHPRHYLEQAAARNTNLEN
MLATEQEVGPQDRIFEFMMNALRLTDGFDPGLFHTRTGLTVASIQQQLTTAEQRGLIEWQHDCIRPTADGRRFLNDLLEI
FLPESRQTTTS

Specific function: Unknown

COG id: COG0635

COG function: function code H; Coproporphyrinogen III oxidase and related Fe-S oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anaerobic coproporphyrinogen-III oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922911, Length=269, Percent_Identity=36.8029739776952, Blast_Score=171, Evalue=9e-43,
Organism=Escherichia coli, GI1789325, Length=389, Percent_Identity=45.5012853470437, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI87082341, Length=407, Percent_Identity=25.3071253071253, Blast_Score=111, Evalue=1e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR004559
- InterPro:   IPR010723
- InterPro:   IPR007197 [H]

Pfam domain/function: PF06969 HemN_C; PF04055 Radical_SAM [H]

EC number: 1.3.3.3

Molecular weight: Translated: 46221; Mature: 46221

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIIPVLSLPDSKSPHLIELPPLGLYIHLPWCVRKCPYCDFNSHAIDPNSALPEAEYVA
CCCCCCEEECCCCCCCCEEECCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
ALKRDLELSLPQIWGRPVTSVFLGGGTPSLFSGASIDAILSYARMLLSFAPETEITLEAN
HHHHHHHCCCHHHCCCCHHEEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
PGTLEAQKFADFRSAGINRLSIGIQSFNPGHLQALGRIHNDAEASRAVEQALQHFSNINL
CCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCE
DLMYALPNQTQDEALQDIEAACGWGVPHISAYHLTLEPNTLFYRQPPKLPDEDTSADMQI
EEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHH
MIERVLAEKGYQHYETSAFAQPGRMCVHNMNYWQYGDYLGIGAGAHSKISFREKIIRQMR
HHHHHHHHCCCHHHHHHHHCCCCHHHHCCCCCEECCCEEEECCCCCCCHHHHHHHHHHHH
HKHPRHYLEQAAARNTNLENMLATEQEVGPQDRIFEFMMNALRLTDGFDPGLFHTRTGLT
HHCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCH
VASIQQQLTTAEQRGLIEWQHDCIRPTADGRRFLNDLLEIFLPESRQTTTS
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MKKIIPVLSLPDSKSPHLIELPPLGLYIHLPWCVRKCPYCDFNSHAIDPNSALPEAEYVA
CCCCCCEEECCCCCCCCEEECCCCCEEEECCHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
ALKRDLELSLPQIWGRPVTSVFLGGGTPSLFSGASIDAILSYARMLLSFAPETEITLEAN
HHHHHHHCCCHHHCCCCHHEEEECCCCCHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECC
PGTLEAQKFADFRSAGINRLSIGIQSFNPGHLQALGRIHNDAEASRAVEQALQHFSNINL
CCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCE
DLMYALPNQTQDEALQDIEAACGWGVPHISAYHLTLEPNTLFYRQPPKLPDEDTSADMQI
EEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCHHHHH
MIERVLAEKGYQHYETSAFAQPGRMCVHNMNYWQYGDYLGIGAGAHSKISFREKIIRQMR
HHHHHHHHCCCHHHHHHHHCCCCHHHHCCCCCEECCCEEEECCCCCCCHHHHHHHHHHHH
HKHPRHYLEQAAARNTNLENMLATEQEVGPQDRIFEFMMNALRLTDGFDPGLFHTRTGLT
HHCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCEECCCCCH
VASIQQQLTTAEQRGLIEWQHDCIRPTADGRRFLNDLLEIFLPESRQTTTS
HHHHHHHHHHHHHCCCHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Coproporphyrinogen III; O2; H+

Specific reaction: coproporphyrinogen-III + O2 + 2 H+ = protoporphyrinogen-IX + 2 CO2 + 2 H2O

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]