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The map label for this gene is yggV [C]

Identifier: 114330336

GI number: 114330336

Start: 316017

End: 316631

Strand: Direct

Name: yggV [C]

Synonym: Neut_0309

Alternate gene names: 114330336

Gene position: 316017-316631 (Clockwise)

Preceding gene: 114330335

Following gene: 114330337

Centisome position: 11.88

GC content: 50.08

Gene sequence:

>615_bases
ATGCAGCACTCCCTGAGCAGGATTGTTATCGCCAGCAATAATGCCGGAAAGCTTGCTGAAATAGGAAAACTGCTGGCTCC
CCTTGGTATTGAAGTGGTTACACAAGCATCGCTTGGAGTAACTGAAGCGGATGAACCTCACATGACGTTTGTGGAAAATG
CGCTGGCCAAAGCACGACATGCGAGTCTCGCAACCGGATTACCCGCATTGGCAGATGATTCCGGGATATGTGTTAATGCT
TTGCAAGGTGCGCCCGGTGTATTGTCCGCCCGCTATGCGGGCGAACCTCGCTCGGATAAACGTAACAATCGCAAACTGGT
TGAAGCACTGCATGGCCAATCCGATCACCGGGCCTATTATTACTGTGTGATTATCCTGTTGCGTCATGGGCAGGATCCGC
AACCTGTCATTATCGAAGATACTTGGCATGGAGAAATCATTGCTGAACCCAAAGGTCAGGGCGGATTTGGTTATGATCCC
CATTTTTTTCTGCCCAAACTGGGTAAAACCGCAGCCGAGCTTTCCATGGAAGAAAAAAACAAGATCAGTCATCGCGGCAA
GGCGCTTGCCAGGCTGGTACAAATACTGGCGGGGAATGAAAAAATGCCGGTTTAG

Upstream 100 bases:

>100_bases
TGTCATGCTTGATATGGCTCAACAGGGGCTGCAAGAGCTGTTTGACCTGCAACGTAAAACACTTGAAACCGCTGCTTCCT
GACAATAAAAGTAACTACAC

Downstream 100 bases:

>100_bases
TTTGACATAACGTGTTTGTGATCATGCGATTGACATGAAAAAAATAATCCCGGTTTTATCCCTGCCTGATTCAAAATCAC
CTCATCTGATTGAGCTTCCT

Product: putative deoxyribonucleotide triphosphate pyrophosphatase

Products: NA

Alternate protein names: Nucleoside triphosphate phosphohydrolase; NTPase [H]

Number of amino acids: Translated: 204; Mature: 204

Protein sequence:

>204_residues
MQHSLSRIVIASNNAGKLAEIGKLLAPLGIEVVTQASLGVTEADEPHMTFVENALAKARHASLATGLPALADDSGICVNA
LQGAPGVLSARYAGEPRSDKRNNRKLVEALHGQSDHRAYYYCVIILLRHGQDPQPVIIEDTWHGEIIAEPKGQGGFGYDP
HFFLPKLGKTAAELSMEEKNKISHRGKALARLVQILAGNEKMPV

Sequences:

>Translated_204_residues
MQHSLSRIVIASNNAGKLAEIGKLLAPLGIEVVTQASLGVTEADEPHMTFVENALAKARHASLATGLPALADDSGICVNA
LQGAPGVLSARYAGEPRSDKRNNRKLVEALHGQSDHRAYYYCVIILLRHGQDPQPVIIEDTWHGEIIAEPKGQGGFGYDP
HFFLPKLGKTAAELSMEEKNKISHRGKALARLVQILAGNEKMPV
>Mature_204_residues
MQHSLSRIVIASNNAGKLAEIGKLLAPLGIEVVTQASLGVTEADEPHMTFVENALAKARHASLATGLPALADDSGICVNA
LQGAPGVLSARYAGEPRSDKRNNRKLVEALHGQSDHRAYYYCVIILLRHGQDPQPVIIEDTWHGEIIAEPKGQGGFGYDP
HFFLPKLGKTAAELSMEEKNKISHRGKALARLVQILAGNEKMPV

Specific function: Hydrolyzes non-standard nucleotides such as XTP and dITP/ITP. Might exclude non-standard purines from DNA precursor pool, preventing thus incorporation into DNA and avoiding chromosomal lesions [H]

COG id: COG0127

COG function: function code F; Xanthosine triphosphate pyrophosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAM1 NTPase family [H]

Homologues:

Organism=Homo sapiens, GI15626999, Length=188, Percent_Identity=31.3829787234043, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI1789324, Length=194, Percent_Identity=50, Blast_Score=209, Evalue=1e-55,
Organism=Caenorhabditis elegans, GI17556833, Length=197, Percent_Identity=29.9492385786802, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI19920712, Length=195, Percent_Identity=31.7948717948718, Blast_Score=86, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002637
- InterPro:   IPR020922 [H]

Pfam domain/function: PF01725 Ham1p_like [H]

EC number: =3.6.1.15 [H]

Molecular weight: Translated: 21984; Mature: 21984

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQHSLSRIVIASNNAGKLAEIGKLLAPLGIEVVTQASLGVTEADEPHMTFVENALAKARH
CCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASLATGLPALADDSGICVNALQGAPGVLSARYAGEPRSDKRNNRKLVEALHGQSDHRAYY
HHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
YCVIILLRHGQDPQPVIIEDTWHGEIIAEPKGQGGFGYDPHFFLPKLGKTAAELSMEEKN
HHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHH
KISHRGKALARLVQILAGNEKMPV
HHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MQHSLSRIVIASNNAGKLAEIGKLLAPLGIEVVTQASLGVTEADEPHMTFVENALAKARH
CCCCCCEEEEEECCCCCHHHHHHHHHHCCHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHH
ASLATGLPALADDSGICVNALQGAPGVLSARYAGEPRSDKRNNRKLVEALHGQSDHRAYY
HHHHHCCCCCCCCCCCEEEECCCCCCCEECCCCCCCCCCCHHHHHHHHHHCCCCCCCHHH
YCVIILLRHGQDPQPVIIEDTWHGEIIAEPKGQGGFGYDPHFFLPKLGKTAAELSMEEKN
HHHHHHHHCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCHHCCHHHHHHHHHHH
KISHRGKALARLVQILAGNEKMPV
HHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]