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The map label for this gene is map [H]

Identifier: 114330334

GI number: 114330334

Start: 314398

End: 315210

Strand: Direct

Name: map [H]

Synonym: Neut_0307

Alternate gene names: 114330334

Gene position: 314398-315210 (Clockwise)

Preceding gene: 114330333

Following gene: 114330335

Centisome position: 11.81

GC content: 47.48

Gene sequence:

>813_bases
GTGGGTGTGGTAGTTCATATTAAAACAGCACAGGAAATTGAAACCATGCGTATTGCCGGGCGACTGGCGTCTGAGGTGCT
AGATTATATTGAACCCTATGTAGTACCCGGCATAACAACAGGTGAGCTGGATAAGCTTTGCCATCATTATATGGTCGATG
TACAGAAAACGATACCGGCTCCTCTTAATTATGCACCGCCTGGTTACAGTCCTTATCCGAAATCTATCTGTACCTCTGTG
AATCATCAGGTTTGTCACGGTGTGCCGGGAGATAAAAAGCTTAAGGACGGAGATATTGTCAATCTCGACATAACGGTCAT
CTATGAAGGTTACCATGGTGATACCAGCCGTATGTATTACGCAGGTGAGCCTTCCATTCAGGCCAAGCGGTTATGCGAGT
TCACCTATGAGGCAATGTGGCGTGGAATCGAGGAGGTGCGTCCGGGCAAACATTTAGGAGATATTGGCCACGCGATCCAG
CGTCTGGCAGAAAAAACTGGTTATGGCATCGTCAGAGAATTTTGTGGGCATGGTATTGGTGCAAAATTCCATGAAGATCC
CCAAGTATTGCACTATGGCCGCGCTGGTACGGGAATCGAGCTTAAACCTGGTATGATTTTTACAATCGAACCCATGATCA
ATGCAGGAAAAGCTGCCATCAAGCAACTCCCGGATGGATGGACAGTGATTACCAAGGATCGCAGTCTGTCTGCGCAATGG
GAGCATACAATACTGGTTACCGATAATGGCTACGAAGTGCTGACCATATCATCGGGATCTCCCGCCAAACCTGACTACCA
TTTCTCAGTCTGA

Upstream 100 bases:

>100_bases
TGGCGCAGTATTCTCGAGCGGTAAAATCAATGAATTGTTTATCTGTAGATTTTTCACAGATTTCTTCAAATATTTATCAT
GATTATTGGAGCAAGTTGGA

Downstream 100 bases:

>100_bases
TGACATTATCCGATAGCACGCTGGAATTACATTATCAGTGCAAAAAATAAGTGATTGATATGCCACGATACAATCATCGT
ACGCTTGCACAAATGCGCCC

Product: methionine aminopeptidase

Products: NA

Alternate protein names: MAP; Peptidase M [H]

Number of amino acids: Translated: 270; Mature: 269

Protein sequence:

>270_residues
MGVVVHIKTAQEIETMRIAGRLASEVLDYIEPYVVPGITTGELDKLCHHYMVDVQKTIPAPLNYAPPGYSPYPKSICTSV
NHQVCHGVPGDKKLKDGDIVNLDITVIYEGYHGDTSRMYYAGEPSIQAKRLCEFTYEAMWRGIEEVRPGKHLGDIGHAIQ
RLAEKTGYGIVREFCGHGIGAKFHEDPQVLHYGRAGTGIELKPGMIFTIEPMINAGKAAIKQLPDGWTVITKDRSLSAQW
EHTILVTDNGYEVLTISSGSPAKPDYHFSV

Sequences:

>Translated_270_residues
MGVVVHIKTAQEIETMRIAGRLASEVLDYIEPYVVPGITTGELDKLCHHYMVDVQKTIPAPLNYAPPGYSPYPKSICTSV
NHQVCHGVPGDKKLKDGDIVNLDITVIYEGYHGDTSRMYYAGEPSIQAKRLCEFTYEAMWRGIEEVRPGKHLGDIGHAIQ
RLAEKTGYGIVREFCGHGIGAKFHEDPQVLHYGRAGTGIELKPGMIFTIEPMINAGKAAIKQLPDGWTVITKDRSLSAQW
EHTILVTDNGYEVLTISSGSPAKPDYHFSV
>Mature_269_residues
GVVVHIKTAQEIETMRIAGRLASEVLDYIEPYVVPGITTGELDKLCHHYMVDVQKTIPAPLNYAPPGYSPYPKSICTSVN
HQVCHGVPGDKKLKDGDIVNLDITVIYEGYHGDTSRMYYAGEPSIQAKRLCEFTYEAMWRGIEEVRPGKHLGDIGHAIQR
LAEKTGYGIVREFCGHGIGAKFHEDPQVLHYGRAGTGIELKPGMIFTIEPMINAGKAAIKQLPDGWTVITKDRSLSAQWE
HTILVTDNGYEVLTISSGSPAKPDYHFSV

Specific function: Removes the amino-terminal methionine from nascent proteins [H]

COG id: COG0024

COG function: function code J; Methionine aminopeptidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24A family [H]

Homologues:

Organism=Homo sapiens, GI164420681, Length=262, Percent_Identity=43.1297709923664, Blast_Score=222, Evalue=3e-58,
Organism=Homo sapiens, GI40385867, Length=254, Percent_Identity=37.7952755905512, Blast_Score=186, Evalue=2e-47,
Organism=Escherichia coli, GI1786364, Length=255, Percent_Identity=58.0392156862745, Blast_Score=320, Evalue=8e-89,
Organism=Escherichia coli, GI1788728, Length=217, Percent_Identity=25.3456221198157, Blast_Score=74, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI71996291, Length=258, Percent_Identity=39.5348837209302, Blast_Score=206, Evalue=8e-54,
Organism=Saccharomyces cerevisiae, GI6323273, Length=262, Percent_Identity=43.8931297709924, Blast_Score=213, Evalue=3e-56,
Organism=Drosophila melanogaster, GI21355531, Length=263, Percent_Identity=42.9657794676806, Blast_Score=222, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24583427, Length=250, Percent_Identity=41.6, Blast_Score=202, Evalue=2e-52,

Paralogues:

None

Copy number: 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR002467 [H]

Pfam domain/function: PF00557 Peptidase_M24 [H]

EC number: =3.4.11.18 [H]

Molecular weight: Translated: 29850; Mature: 29719

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: PS00680 MAP_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVVVHIKTAQEIETMRIAGRLASEVLDYIEPYVVPGITTGELDKLCHHYMVDVQKTIPA
CCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
PLNYAPPGYSPYPKSICTSVNHQVCHGVPGDKKLKDGDIVNLDITVIYEGYHGDTSRMYY
CCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEE
AGEPSIQAKRLCEFTYEAMWRGIEEVRPGKHLGDIGHAIQRLAEKTGYGIVREFCGHGIG
CCCCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
AKFHEDPQVLHYGRAGTGIELKPGMIFTIEPMINAGKAAIKQLPDGWTVITKDRSLSAQW
CCCCCCCCEEEECCCCCCEEECCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCC
EHTILVTDNGYEVLTISSGSPAKPDYHFSV
CEEEEEECCCEEEEEECCCCCCCCCCCCCC
>Mature Secondary Structure 
GVVVHIKTAQEIETMRIAGRLASEVLDYIEPYVVPGITTGELDKLCHHYMVDVQKTIPA
CEEEEECCHHHHHHHHHHHHHHHHHHHHHCCEEECCCCCHHHHHHHHHHHHHHHHHCCC
PLNYAPPGYSPYPKSICTSVNHQVCHGVPGDKKLKDGDIVNLDITVIYEGYHGDTSRMYY
CCCCCCCCCCCCCHHHHHHCCHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCEEEE
AGEPSIQAKRLCEFTYEAMWRGIEEVRPGKHLGDIGHAIQRLAEKTGYGIVREFCGHGIG
CCCCCHHHHHHHHHHHHHHHCCHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCC
AKFHEDPQVLHYGRAGTGIELKPGMIFTIEPMINAGKAAIKQLPDGWTVITKDRSLSAQW
CCCCCCCCEEEECCCCCCEEECCCEEEEECCCCCCHHHHHHHCCCCCEEEEECCCCCCCC
EHTILVTDNGYEVLTISSGSPAKPDYHFSV
CEEEEEECCCEEEEEECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]