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The map label for this gene is gpmA1 [H]

Identifier: 114330292

GI number: 114330292

Start: 277300

End: 278010

Strand: Reverse

Name: gpmA1 [H]

Synonym: Neut_0265

Alternate gene names: 114330292

Gene position: 278010-277300 (Counterclockwise)

Preceding gene: 114330293

Following gene: 114330285

Centisome position: 10.45

GC content: 49.79

Gene sequence:

>711_bases
GTGAGTAAAACAGAAAAGTTAACCCGGCTGGTATTGCTCCGCCATGGGAAAAGTGTCTGGAATAAAGACAGGCACTTTAC
TGGTTGGAGTGATATTGCACTCAGCTTGCAAGGTGAGGAGGAAGCAAGAAGAGCAGGCCAGCGTCTCAAGCAGGCAGGTT
TTAGTTTTGATATCTGTTTCTGTTCGGAGCTAAAGCGTGCACGAGATACGCTTGCGTTTGTGCAATCGGAAATGAGCCTG
AGCCATCTCCCAGCTTATCAGAGCTGGCGGCTGAATGAACGTCATTACGGCGCACTGGAGGGCATGCGTCCTTGGGCTGC
CATTCGTAAATTTGGTATCTGGCCGGTACTGAAAAGCCAGCTCCATTTTGATGCGGTGCCTCCATTGCTGATGGCAAATG
ATCCTCGTGTACCCGCCAGCCAGCAGCGCTATGCAGCAGTTAATCATGCCCAGTTACCTCTGGCAGAAAGTATGCAACAA
GCATTGGTGCGCGTACAGCCCTTCTGGCAGCAAACGATTCTCCCTGAAATCAGGCAGGGGAAACGTTTGCTAATTGTCTC
GCACAAGGGGCTTTTAAGAACTTTAGTTATGCAATTGGAAGGATTGACAGGCGCACAGGTGATGCGCTTATCAATTACGA
CAGGTCAGCCGCTTTGTTACGAGCTGGATAGCTCGCTCAACCCAGTTAACCGTTATTATTTACCAGGTTGA

Upstream 100 bases:

>100_bases
ATCTGGCAGGAATCTACGGCGGCAGTAAAGAAAAATAATATACGGGATTGATGTTTAATATTTTTGTAACTTTACTGTCT
CTAAAAATCTACAATCATTT

Downstream 100 bases:

>100_bases
GGCGCGCCAGAATTTTCGACAGATTTTCCGGATCGGAGAAATGATTATTTTTTATCCCGATCAGTTTGACTGGTGATGCC
GGATAAGACCCCGGTAGAAA

Product: phosphoglycerate mutase 1 family protein

Products: NA

Alternate protein names: BPG-dependent PGAM 1; PGAM 1; Phosphoglyceromutase 1; dPGM 1 [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MSKTEKLTRLVLLRHGKSVWNKDRHFTGWSDIALSLQGEEEARRAGQRLKQAGFSFDICFCSELKRARDTLAFVQSEMSL
SHLPAYQSWRLNERHYGALEGMRPWAAIRKFGIWPVLKSQLHFDAVPPLLMANDPRVPASQQRYAAVNHAQLPLAESMQQ
ALVRVQPFWQQTILPEIRQGKRLLIVSHKGLLRTLVMQLEGLTGAQVMRLSITTGQPLCYELDSSLNPVNRYYLPG

Sequences:

>Translated_236_residues
MSKTEKLTRLVLLRHGKSVWNKDRHFTGWSDIALSLQGEEEARRAGQRLKQAGFSFDICFCSELKRARDTLAFVQSEMSL
SHLPAYQSWRLNERHYGALEGMRPWAAIRKFGIWPVLKSQLHFDAVPPLLMANDPRVPASQQRYAAVNHAQLPLAESMQQ
ALVRVQPFWQQTILPEIRQGKRLLIVSHKGLLRTLVMQLEGLTGAQVMRLSITTGQPLCYELDSSLNPVNRYYLPG
>Mature_235_residues
SKTEKLTRLVLLRHGKSVWNKDRHFTGWSDIALSLQGEEEARRAGQRLKQAGFSFDICFCSELKRARDTLAFVQSEMSLS
HLPAYQSWRLNERHYGALEGMRPWAAIRKFGIWPVLKSQLHFDAVPPLLMANDPRVPASQQRYAAVNHAQLPLAESMQQA
LVRVQPFWQQTILPEIRQGKRLLIVSHKGLLRTLVMQLEGLTGAQVMRLSITTGQPLCYELDSSLNPVNRYYLPG

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate [H]

COG id: COG0588

COG function: function code G; Phosphoglycerate mutase 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily [H]

Homologues:

Organism=Homo sapiens, GI4505753, Length=223, Percent_Identity=43.0493273542601, Blast_Score=181, Evalue=5e-46,
Organism=Homo sapiens, GI50593010, Length=223, Percent_Identity=40.3587443946188, Blast_Score=181, Evalue=6e-46,
Organism=Homo sapiens, GI71274132, Length=223, Percent_Identity=40.3587443946188, Blast_Score=166, Evalue=1e-41,
Organism=Homo sapiens, GI4502445, Length=232, Percent_Identity=34.9137931034483, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI40353764, Length=232, Percent_Identity=34.9137931034483, Blast_Score=150, Evalue=1e-36,
Organism=Homo sapiens, GI310129614, Length=161, Percent_Identity=41.6149068322981, Blast_Score=114, Evalue=6e-26,
Organism=Escherichia coli, GI1786970, Length=228, Percent_Identity=44.2982456140351, Blast_Score=213, Evalue=6e-57,
Organism=Saccharomyces cerevisiae, GI6322697, Length=229, Percent_Identity=39.3013100436681, Blast_Score=173, Evalue=2e-44,
Organism=Saccharomyces cerevisiae, GI6324516, Length=275, Percent_Identity=27.2727272727273, Blast_Score=109, Evalue=3e-25,
Organism=Saccharomyces cerevisiae, GI6320183, Length=279, Percent_Identity=27.5985663082437, Blast_Score=99, Evalue=4e-22,
Organism=Saccharomyces cerevisiae, GI6324857, Length=101, Percent_Identity=33.6633663366337, Blast_Score=65, Evalue=7e-12,
Organism=Drosophila melanogaster, GI24646216, Length=230, Percent_Identity=36.5217391304348, Blast_Score=159, Evalue=1e-39,
Organism=Drosophila melanogaster, GI85725270, Length=230, Percent_Identity=36.0869565217391, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI85725272, Length=230, Percent_Identity=36.0869565217391, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24650981, Length=230, Percent_Identity=36.0869565217391, Blast_Score=154, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571815, Length=221, Percent_Identity=33.9366515837104, Blast_Score=132, Evalue=3e-31,
Organism=Drosophila melanogaster, GI28571817, Length=221, Percent_Identity=33.9366515837104, Blast_Score=131, Evalue=3e-31,
Organism=Drosophila melanogaster, GI24648979, Length=221, Percent_Identity=33.9366515837104, Blast_Score=131, Evalue=3e-31,

Paralogues:

None

Copy number: 960 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013078
- InterPro:   IPR001345
- InterPro:   IPR005952 [H]

Pfam domain/function: PF00300 PGAM [H]

EC number: =5.4.2.1 [H]

Molecular weight: Translated: 26962; Mature: 26830

Theoretical pI: Translated: 10.41; Mature: 10.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKTEKLTRLVLLRHGKSVWNKDRHFTGWSDIALSLQGEEEARRAGQRLKQAGFSFDICF
CCHHHHHHHHHHHHHCHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHHHHHCCCCEEHHH
CSELKRARDTLAFVQSEMSLSHLPAYQSWRLNERHYGALEGMRPWAAIRKFGIWPVLKSQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCHHHHHH
LHFDAVPPLLMANDPRVPASQQRYAAVNHAQLPLAESMQQALVRVQPFWQQTILPEIRQG
HCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KRLLIVSHKGLLRTLVMQLEGLTGAQVMRLSITTGQPLCYELDSSLNPVNRYYLPG
CEEEEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
SKTEKLTRLVLLRHGKSVWNKDRHFTGWSDIALSLQGEEEARRAGQRLKQAGFSFDICF
CHHHHHHHHHHHHHCHHHHCCCCCCCCHHHEEEEECCHHHHHHHHHHHHHCCCCEEHHH
CSELKRARDTLAFVQSEMSLSHLPAYQSWRLNERHYGALEGMRPWAAIRKFGIWPVLKSQ
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCHHHHHHHHCCCHHHHHH
LHFDAVPPLLMANDPRVPASQQRYAAVNHAQLPLAESMQQALVRVQPFWQQTILPEIRQG
HCCCCCCCCEECCCCCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
KRLLIVSHKGLLRTLVMQLEGLTGAQVMRLSITTGQPLCYELDSSLNPVNRYYLPG
CEEEEEECHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]