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The map label for this gene is fucA [H]

Identifier: 114330246

GI number: 114330246

Start: 222829

End: 223611

Strand: Direct

Name: fucA [H]

Synonym: Neut_0218

Alternate gene names: 114330246

Gene position: 222829-223611 (Clockwise)

Preceding gene: 114330241

Following gene: 114330247

Centisome position: 8.37

GC content: 52.11

Gene sequence:

>783_bases
ATGAGTGGTGAAACGTTTGATCTTGACAAGCAGCAGTTGATGCAACGTGAATTCGATCAGATGGAGAATAAGCTGCCGGG
GGCAATTTATTCTCTGCGCCAGAAGGTAGCTTTGACTTGTCGTATTTTATTTGATAATGGCCATGATTCCGGGCTGGCCG
GACAAATTACCGCGCGCGGGGAGGTGCCGGGCACGTTTTTGACGCAGCGGCTGGGATTCGGTTTTGACGAGATCAGTGCC
GGGAATTTGTTGCTGGTTGATGAGGATTTGCTGGTGCTGGAAGGGGAGGGTATGCCTAATCCCGCGAATCGTTTTCATTC
CTGGGTATATCGTGCACGCCCCGATGTACATTGCATTGTCCACTCCCATGCATTGCATACAGCGGCACTGAGTATGCTGG
AAACACCACTCATCATTTCGCACATGGATAACTGTGTGCTGTATGGTGATGTGGCTTTTTTACCGAAATGGCCGGGTGTT
CCGGTGGGTAACGAAGAAGGTGGGTTGATTGCCGAGGCATTGGGTAGTAAACGCGCATTGATGCTTGCTCATCACGGACT
GCTGGTGGCTTGCAGTAATGTTGAGGAAGCCTGTTTGATCGCGCTGGCATTTGAGCGGGCTGCACGCATGCAGTTGCTGG
CAAGTGCGGTTGGCGAAATTCAGCCGATCGATCCGACGCTGGGACGAGAGGCGCATGACTGGATTTTACATGCGCAACGC
AGTGCGAGCGCCTTTGCCTATTACGCCCGACGTTCTCTGAAACATTGTTCTGATTGTCTGTGA

Upstream 100 bases:

>100_bases
ATTTCTATCGGGTTTTGCTTGCAACCACGAAAGAAATACGGAAAATCGCACTGGTAATAACAATGAAGTTTCTTTGTGGA
AAAGAGGGGGATTCCGGCTT

Downstream 100 bases:

>100_bases
GAGTGATGATTCTTACGTCGCTCACTCAGCGGTTTGCCATCTGGTTTGCGCTGGTGGCGTTATTGCCGATTGCGTTGGTC
GGCTATGGTTTGCTGCACAT

Product: class II aldolase/adducin domain protein

Products: NA

Alternate protein names: L-fuculose-1-phosphate aldolase [H]

Number of amino acids: Translated: 260; Mature: 259

Protein sequence:

>260_residues
MSGETFDLDKQQLMQREFDQMENKLPGAIYSLRQKVALTCRILFDNGHDSGLAGQITARGEVPGTFLTQRLGFGFDEISA
GNLLLVDEDLLVLEGEGMPNPANRFHSWVYRARPDVHCIVHSHALHTAALSMLETPLIISHMDNCVLYGDVAFLPKWPGV
PVGNEEGGLIAEALGSKRALMLAHHGLLVACSNVEEACLIALAFERAARMQLLASAVGEIQPIDPTLGREAHDWILHAQR
SASAFAYYARRSLKHCSDCL

Sequences:

>Translated_260_residues
MSGETFDLDKQQLMQREFDQMENKLPGAIYSLRQKVALTCRILFDNGHDSGLAGQITARGEVPGTFLTQRLGFGFDEISA
GNLLLVDEDLLVLEGEGMPNPANRFHSWVYRARPDVHCIVHSHALHTAALSMLETPLIISHMDNCVLYGDVAFLPKWPGV
PVGNEEGGLIAEALGSKRALMLAHHGLLVACSNVEEACLIALAFERAARMQLLASAVGEIQPIDPTLGREAHDWILHAQR
SASAFAYYARRSLKHCSDCL
>Mature_259_residues
SGETFDLDKQQLMQREFDQMENKLPGAIYSLRQKVALTCRILFDNGHDSGLAGQITARGEVPGTFLTQRLGFGFDEISAG
NLLLVDEDLLVLEGEGMPNPANRFHSWVYRARPDVHCIVHSHALHTAALSMLETPLIISHMDNCVLYGDVAFLPKWPGVP
VGNEEGGLIAEALGSKRALMLAHHGLLVACSNVEEACLIALAFERAARMQLLASAVGEIQPIDPTLGREAHDWILHAQRS
ASAFAYYARRSLKHCSDCL

Specific function: Fucose metabolism; third step. [C]

COG id: COG0235

COG function: function code G; Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldolase class II family. AraD/FucA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789164, Length=194, Percent_Identity=27.8350515463918, Blast_Score=75, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI115533216, Length=170, Percent_Identity=27.6470588235294, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI115533218, Length=185, Percent_Identity=26.4864864864865, Blast_Score=64, Evalue=6e-11,
Organism=Drosophila melanogaster, GI281363755, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363751, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655690, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24655685, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363763, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363757, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136738, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363761, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363759, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI281363753, Length=194, Percent_Identity=33.5051546391753, Blast_Score=67, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001303
- InterPro:   IPR004782 [H]

Pfam domain/function: PF00596 Aldolase_II [H]

EC number: =4.1.2.17 [H]

Molecular weight: Translated: 28543; Mature: 28412

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGETFDLDKQQLMQREFDQMENKLPGAIYSLRQKVALTCRILFDNGHDSGLAGQITARG
CCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEECCCCCCCEEEEEECC
EVPGTFLTQRLGFGFDEISAGNLLLVDEDLLVLEGEGMPNPANRFHSWVYRARPDVHCIV
CCCHHHHHHHHCCCCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEE
HSHALHTAALSMLETPLIISHMDNCVLYGDVAFLPKWPGVPVGNEEGGLIAEALGSKRAL
EHHHHHHHHHHHHHCCHHHHHCCCEEEEECEEECCCCCCCCCCCCCCCCHHHHHCCCCEE
MLAHHGLLVACSNVEEACLIALAFERAARMQLLASAVGEIQPIDPTLGREAHDWILHAQR
EEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SASAFAYYARRSLKHCSDCL
HHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SGETFDLDKQQLMQREFDQMENKLPGAIYSLRQKVALTCRILFDNGHDSGLAGQITARG
CCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHEEEEEEEEECCCCCCCEEEEEECC
EVPGTFLTQRLGFGFDEISAGNLLLVDEDLLVLEGEGMPNPANRFHSWVYRARPDVHCIV
CCCHHHHHHHHCCCCCCCCCCCEEEEECCEEEEECCCCCCHHHHHHHHHHHCCCCEEEEE
HSHALHTAALSMLETPLIISHMDNCVLYGDVAFLPKWPGVPVGNEEGGLIAEALGSKRAL
EHHHHHHHHHHHHHCCHHHHHCCCEEEEECEEECCCCCCCCCCCCCCCCHHHHHCCCCEE
MLAHHGLLVACSNVEEACLIALAFERAARMQLLASAVGEIQPIDPTLGREAHDWILHAQR
EEECCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHH
SASAFAYYARRSLKHCSDCL
HHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]