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The map label for this gene is yciK [H]

Identifier: 114330234

GI number: 114330234

Start: 210402

End: 211199

Strand: Reverse

Name: yciK [H]

Synonym: Neut_0205

Alternate gene names: 114330234

Gene position: 211199-210402 (Counterclockwise)

Preceding gene: 114330235

Following gene: 114330233

Centisome position: 7.94

GC content: 47.87

Gene sequence:

>798_bases
TTGTGGTTTTTAACTTCTATCGGTCGTGCTGAGATAAATATATTGGATACTTTAAAAACTTATCCGGATGACCGGAATTT
GCTTGCAGACCGGGTTATCCTGGTTACAGGTGCAGGACAAGGTATTGGGCGCACTGCAGCACTCACTTTCGCAAAATATG
GCGCCACGATTATTTTACATGGCCGTAAAACCGAGAAGCTTGAGCAGGTTTATGATGAAATCGAGACGCTCGGCAGAGCA
TCAGCAATCTTTCTGCCATTTGATTTCGAACAGGCTACTGAAACTGGCATTGTGGAACTAGCTGGGGCAATAGCCTCCCA
AATTGGTCGGCTGGATGGTATTTTGCACAATGTCGCCTGGACCACCGGCCCAATGCCACTTGAATTCCATACACTTGAGC
ACTGGCAAACCACCATGCAGATCAATCTTCTCATCCCTGCAATGCTGACTCGCGCCTGTTTTCCGTTGCTCAAGACCGCC
CAGGATGCCAGTGTAATCATGACGGGAGACACCCACGGCCAAGTACCCACAGCCTACTGGGGTGCTTTTGCAGTAGCGAA
AGCAGGGGTGGAAGCATTGGTCAAAATTCAGTCTGAGGAGTGGGAGATTTATCCAAATTTACGCATTAACGCACTGATTC
CTGGAGCTACAGACACGCCACAACGTACCAAAACTCATCCGGGCAGCAATAACCGTTTATTACCCAAACCGGCAGATCTG
ATGGGGACTTATCTCTTCCTGATGGGACCAAATAGTACTGGAGTAACTGGCAAAACGTTCAATTGCCAAAAAGATTAA

Upstream 100 bases:

>100_bases
GTATGGGTGGCATGGGCGGTATGGACATGTAACCGACTCCAATCGGTCTATCTGTTAACAATAATGAACCACAACGGATC
GGTATGCAAAAAACCGGACG

Downstream 100 bases:

>100_bases
CCGCACAACGGACAGGAAATCTGCCCCGGTTGTTAGAAGCGAGTATAATTGGCTATAAAGGGGTGTGGTGTGATTCGCTG
AAAAACAAGCTGCGGCACAA

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 265; Mature: 265

Protein sequence:

>265_residues
MWFLTSIGRAEINILDTLKTYPDDRNLLADRVILVTGAGQGIGRTAALTFAKYGATIILHGRKTEKLEQVYDEIETLGRA
SAIFLPFDFEQATETGIVELAGAIASQIGRLDGILHNVAWTTGPMPLEFHTLEHWQTTMQINLLIPAMLTRACFPLLKTA
QDASVIMTGDTHGQVPTAYWGAFAVAKAGVEALVKIQSEEWEIYPNLRINALIPGATDTPQRTKTHPGSNNRLLPKPADL
MGTYLFLMGPNSTGVTGKTFNCQKD

Sequences:

>Translated_265_residues
MWFLTSIGRAEINILDTLKTYPDDRNLLADRVILVTGAGQGIGRTAALTFAKYGATIILHGRKTEKLEQVYDEIETLGRA
SAIFLPFDFEQATETGIVELAGAIASQIGRLDGILHNVAWTTGPMPLEFHTLEHWQTTMQINLLIPAMLTRACFPLLKTA
QDASVIMTGDTHGQVPTAYWGAFAVAKAGVEALVKIQSEEWEIYPNLRINALIPGATDTPQRTKTHPGSNNRLLPKPADL
MGTYLFLMGPNSTGVTGKTFNCQKD
>Mature_265_residues
MWFLTSIGRAEINILDTLKTYPDDRNLLADRVILVTGAGQGIGRTAALTFAKYGATIILHGRKTEKLEQVYDEIETLGRA
SAIFLPFDFEQATETGIVELAGAIASQIGRLDGILHNVAWTTGPMPLEFHTLEHWQTTMQINLLIPAMLTRACFPLLKTA
QDASVIMTGDTHGQVPTAYWGAFAVAKAGVEALVKIQSEEWEIYPNLRINALIPGATDTPQRTKTHPGSNNRLLPKPADL
MGTYLFLMGPNSTGVTGKTFNCQKD

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32455239, Length=209, Percent_Identity=27.7511961722488, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI5031765, Length=209, Percent_Identity=27.7511961722488, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI32483357, Length=252, Percent_Identity=25.7936507936508, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1787526, Length=244, Percent_Identity=40.5737704918033, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=28.6852589641434, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI87082160, Length=262, Percent_Identity=23.6641221374046, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1787905, Length=247, Percent_Identity=26.3157894736842, Blast_Score=62, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17562910, Length=251, Percent_Identity=24.7011952191235, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=196, Percent_Identity=29.0816326530612, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=199, Percent_Identity=28.643216080402, Blast_Score=72, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=29.1005291005291, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17536025, Length=192, Percent_Identity=31.25, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17536651, Length=189, Percent_Identity=30.6878306878307, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17544670, Length=246, Percent_Identity=22.7642276422764, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=192, Percent_Identity=26.0416666666667, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17562904, Length=247, Percent_Identity=22.2672064777328, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=186, Percent_Identity=29.0322580645161, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17562906, Length=193, Percent_Identity=27.4611398963731, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560220, Length=199, Percent_Identity=26.1306532663317, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=198, Percent_Identity=24.2424242424242, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI28571526, Length=198, Percent_Identity=31.3131313131313, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24644339, Length=193, Percent_Identity=29.0155440414508, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28983; Mature: 28983

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MWFLTSIGRAEINILDTLKTYPDDRNLLADRVILVTGAGQGIGRTAALTFAKYGATIILH
CEEECCCCCCEEEEEHHHHCCCCCCCHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEE
GRKTEKLEQVYDEIETLGRASAIFLPFDFEQATETGIVELAGAIASQIGRLDGILHNVAW
CCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTGPMPLEFHTLEHWQTTMQINLLIPAMLTRACFPLLKTAQDASVIMTGDTHGQVPTAYW
CCCCCCEEEEEHHHHEEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
GAFAVAKAGVEALVKIQSEEWEIYPNLRINALIPGATDTPQRTKTHPGSNNRLLPKPADL
HHHHHHHHHHHHEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCHHH
MGTYLFLMGPNSTGVTGKTFNCQKD
HEEEEEEECCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MWFLTSIGRAEINILDTLKTYPDDRNLLADRVILVTGAGQGIGRTAALTFAKYGATIILH
CEEECCCCCCEEEEEHHHHCCCCCCCHHCCEEEEEEECCCCCCHHHHHHHHHCCCEEEEE
GRKTEKLEQVYDEIETLGRASAIFLPFDFEQATETGIVELAGAIASQIGRLDGILHNVAW
CCCHHHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TTGPMPLEFHTLEHWQTTMQINLLIPAMLTRACFPLLKTAQDASVIMTGDTHGQVPTAYW
CCCCCCEEEEEHHHHEEEEEEEEHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
GAFAVAKAGVEALVKIQSEEWEIYPNLRINALIPGATDTPQRTKTHPGSNNRLLPKPADL
HHHHHHHHHHHHEEEEECCCEEEECCCEEEEEECCCCCCCCCCCCCCCCCCEECCCCHHH
MGTYLFLMGPNSTGVTGKTFNCQKD
HEEEEEEECCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]