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The map label for this gene is clpX

Identifier: 114330231

GI number: 114330231

Start: 206781

End: 208064

Strand: Reverse

Name: clpX

Synonym: Neut_0202

Alternate gene names: 114330231

Gene position: 208064-206781 (Counterclockwise)

Preceding gene: 114330232

Following gene: 114330230

Centisome position: 7.82

GC content: 42.06

Gene sequence:

>1284_bases
ATGTCTGAAAAAACAAATGACGAAAAACTTTTGTATTGTTCTTTTTGCGGAAAGAGTCAGCGAGAGGTCCGAAAGTTAAT
TGCCGGGCCATCTGTATTCATTTGCGATGAGTGTATCGACCTTTGTAATGACATTATTCGCGAAGAAATACAGGTTGATG
AAACGGCCAAACTATCTAAAACAAGTTTGCCGACCCCACATGAAATTTGTGAAACACTGGATCAATATGTCATTGGACAG
GAATCTGCAAAAAAAATACTGTCTGTTGCAGTTTACAACCACTATAAGCGATTAAGAAATCTATCAAAAGTTAATGCTGG
TAGCGATGACATTGAACTTGCCAAAAGCAATATATTGCTGATTGGCCCTACCGGATCTGGCAAGACCTTACTGGCACAGA
CACTGGCAAGATTGCTAGATGTACCGTTTGTTATTGCTGATGCAACGACGCTGACAGAAGCAGGATATGTCGGTGAGGAT
GTAGAAAATATTATTCAGAAGTTGCTGCAAGCAAGTAACCACGATGTTGAAAAGGCCCAGCGCGGAATCGTATACATCGA
CGAGATAGATAAAATCTCGCGTAAATCAGACAACCCTTCCATCACTCGGGATGTTTCAGGAGAAGGTGTACAACAGGCAC
TACTCAAACTGATTGAGGGTACAGCAGCCTTGGTACCTCCTCAAGGTGGTCGCAAACATCCCAATCAGGAATTTATTCAG
GTTGATACCACAAATATTCTGTTCATTTGTGGTGGGGCATTTGATGGTATCGATAAAATCATACGTGCACGATCTGAAAA
AAGTGGCATAGGCTTTGGTGCGGATGTCATCAACCAGAACGATCGCAAGGAATTAAACAAGATATTGGGTGACATTGAAC
CAGAAGATCTAATTAAATACGGCTTGATTCCGGAGTTTATCGGGCGTTTACCAGTCGTGGCAACGTTGCGTGAATTGAAC
GAGGCAGCACTGATCCAAATTTTGATTGAACCCAAAAATGCACTGGTTAAACAATACAGCAAGCTATTCAGCATGGAAGG
AGGAGTTGAATTGGAATTCCGCGAACAGGCTCTTGTAACAATTGCCAGAAAAGCGCTTGCACGGAAAACTGGAGCACGTG
GATTACGTTCTATTCTTGAGGAAACACTGCTGGATATTATGTATGATCTGCCTTCAATCAAAAACGTCTCAAAAGTGGTG
ATCGAAAGCAGCTCTACAAATGATGATCTTCAACCTATCATAATTTATGCTGAAAAGCCCAAGCTGGCCAGAAGCTCGAA
ATAG

Upstream 100 bases:

>100_bases
TGGATGCAGTATTAACGAGCCGGAAAGTAAAACACGAGTAAAATCAAATTGCTCCTGCTGAACAAGAGCAATATTCGTTT
GATGATTGTGGGGTGGAATA

Downstream 100 bases:

>100_bases
TACAAATTCTTTTAAGAGTTTGTTTTTAGCACACTGCGGGTACCTGTTTTTCACAGGTGTCACCATATCTTATCCTATCC
ATGTTTTCTGCAGGATGTAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 426

Protein sequence:

>427_residues
MSEKTNDEKLLYCSFCGKSQREVRKLIAGPSVFICDECIDLCNDIIREEIQVDETAKLSKTSLPTPHEICETLDQYVIGQ
ESAKKILSVAVYNHYKRLRNLSKVNAGSDDIELAKSNILLIGPTGSGKTLLAQTLARLLDVPFVIADATTLTEAGYVGED
VENIIQKLLQASNHDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTAALVPPQGGRKHPNQEFIQ
VDTTNILFICGGAFDGIDKIIRARSEKSGIGFGADVINQNDRKELNKILGDIEPEDLIKYGLIPEFIGRLPVVATLRELN
EAALIQILIEPKNALVKQYSKLFSMEGGVELEFREQALVTIARKALARKTGARGLRSILEETLLDIMYDLPSIKNVSKVV
IESSSTNDDLQPIIIYAEKPKLARSSK

Sequences:

>Translated_427_residues
MSEKTNDEKLLYCSFCGKSQREVRKLIAGPSVFICDECIDLCNDIIREEIQVDETAKLSKTSLPTPHEICETLDQYVIGQ
ESAKKILSVAVYNHYKRLRNLSKVNAGSDDIELAKSNILLIGPTGSGKTLLAQTLARLLDVPFVIADATTLTEAGYVGED
VENIIQKLLQASNHDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTAALVPPQGGRKHPNQEFIQ
VDTTNILFICGGAFDGIDKIIRARSEKSGIGFGADVINQNDRKELNKILGDIEPEDLIKYGLIPEFIGRLPVVATLRELN
EAALIQILIEPKNALVKQYSKLFSMEGGVELEFREQALVTIARKALARKTGARGLRSILEETLLDIMYDLPSIKNVSKVV
IESSSTNDDLQPIIIYAEKPKLARSSK
>Mature_426_residues
SEKTNDEKLLYCSFCGKSQREVRKLIAGPSVFICDECIDLCNDIIREEIQVDETAKLSKTSLPTPHEICETLDQYVIGQE
SAKKILSVAVYNHYKRLRNLSKVNAGSDDIELAKSNILLIGPTGSGKTLLAQTLARLLDVPFVIADATTLTEAGYVGEDV
ENIIQKLLQASNHDVEKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTAALVPPQGGRKHPNQEFIQV
DTTNILFICGGAFDGIDKIIRARSEKSGIGFGADVINQNDRKELNKILGDIEPEDLIKYGLIPEFIGRLPVVATLRELNE
AALIQILIEPKNALVKQYSKLFSMEGGVELEFREQALVTIARKALARKTGARGLRSILEETLLDIMYDLPSIKNVSKVVI
ESSSTNDDLQPIIIYAEKPKLARSSK

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family

Homologues:

Organism=Homo sapiens, GI7242140, Length=312, Percent_Identity=54.1666666666667, Blast_Score=312, Evalue=3e-85,
Organism=Escherichia coli, GI1786642, Length=429, Percent_Identity=71.7948717948718, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1790366, Length=108, Percent_Identity=41.6666666666667, Blast_Score=95, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71982908, Length=293, Percent_Identity=46.7576791808874, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71982905, Length=293, Percent_Identity=46.7576791808874, Blast_Score=263, Evalue=1e-70,
Organism=Caenorhabditis elegans, GI71988663, Length=390, Percent_Identity=40.5128205128205, Blast_Score=258, Evalue=4e-69,
Organism=Caenorhabditis elegans, GI71988660, Length=249, Percent_Identity=44.9799196787149, Blast_Score=188, Evalue=4e-48,
Organism=Saccharomyces cerevisiae, GI6319704, Length=432, Percent_Identity=40.2777777777778, Blast_Score=265, Evalue=1e-71,
Organism=Drosophila melanogaster, GI24648291, Length=300, Percent_Identity=49.3333333333333, Blast_Score=290, Evalue=9e-79,
Organism=Drosophila melanogaster, GI24648289, Length=300, Percent_Identity=49.3333333333333, Blast_Score=290, Evalue=9e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CLPX_NITEC (Q0AJI3)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746453.1
- ProteinModelPortal:   Q0AJI3
- STRING:   Q0AJI3
- GeneID:   4272443
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0202
- NMPDR:   fig|335283.3.peg.1678
- eggNOG:   COG1219
- HOGENOM:   HBG745965
- OMA:   CGKSQEQ
- PhylomeDB:   Q0AJI3
- ProtClustDB:   PRK05342
- BioCyc:   NEUT335283:NEUT_0202-MONOMER
- HAMAP:   MF_00175
- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603
- PANTHER:   PTHR11262:SF4
- SMART:   SM00382
- TIGRFAMs:   TIGR00382

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX

EC number: NA

Molecular weight: Translated: 47102; Mature: 46971

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKTNDEKLLYCSFCGKSQREVRKLIAGPSVFICDECIDLCNDIIREEIQVDETAKLSK
CCCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHC
TSLPTPHEICETLDQYVIGQESAKKILSVAVYNHYKRLRNLSKVNAGSDDIELAKSNILL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEE
IGPTGSGKTLLAQTLARLLDVPFVIADATTLTEAGYVGEDVENIIQKLLQASNHDVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTAALVPPQGGRKHPNQEFIQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEE
VDTTNILFICGGAFDGIDKIIRARSEKSGIGFGADVINQNDRKELNKILGDIEPEDLIKY
EECCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHH
GLIPEFIGRLPVVATLRELNEAALIQILIEPKNALVKQYSKLFSMEGGVELEFREQALVT
CCCHHHHCCCHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
IARKALARKTGARGLRSILEETLLDIMYDLPSIKNVSKVVIESSSTNDDLQPIIIYAEKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCEEEEEECCC
KLARSSK
CCCCCCC
>Mature Secondary Structure 
SEKTNDEKLLYCSFCGKSQREVRKLIAGPSVFICDECIDLCNDIIREEIQVDETAKLSK
CCCCCCCEEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHCCCCHHHHHC
TSLPTPHEICETLDQYVIGQESAKKILSVAVYNHYKRLRNLSKVNAGSDDIELAKSNILL
CCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCEEE
IGPTGSGKTLLAQTLARLLDVPFVIADATTLTEAGYVGEDVENIIQKLLQASNHDVEKAQ
EECCCCCHHHHHHHHHHHHCCCEEEECCHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHH
RGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTAALVPPQGGRKHPNQEFIQ
CCEEEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCCCCEEE
VDTTNILFICGGAFDGIDKIIRARSEKSGIGFGADVINQNDRKELNKILGDIEPEDLIKY
EECCEEEEEECCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHHCCCCHHHHHHH
GLIPEFIGRLPVVATLRELNEAALIQILIEPKNALVKQYSKLFSMEGGVELEFREQALVT
CCCHHHHCCCHHHHHHHHHCHHHEEEEEECCHHHHHHHHHHHHHCCCCCEEHHHHHHHHH
IARKALARKTGARGLRSILEETLLDIMYDLPSIKNVSKVVIESSSTNDDLQPIIIYAEKP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHEECCCCCCCCCEEEEEECCC
KLARSSK
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA