Click here to switch to the map view.

The map label for this gene is uppP

Identifier: 114330224

GI number: 114330224

Start: 194603

End: 195424

Strand: Reverse

Name: uppP

Synonym: Neut_0195

Alternate gene names: 114330224

Gene position: 195424-194603 (Counterclockwise)

Preceding gene: 114330225

Following gene: 114330220

Centisome position: 7.34

GC content: 47.69

Gene sequence:

>822_bases
ATGGACTGGCTGATTCTCATCAAAGCATTTCTGCTTGGTATTGTTGAAGGACTGACCGAGTTTTTGCCAATCTCATCTAC
CGGACACCTAATACTGGCGGGCGATTTACTGGATTTTAATGACGATAAAGCTCAGGTTTTTACGGTAGCAATACAGCTGG
GGGCGATTCTCTCCGTTTGTTGGGAATATCGTGCACGGCTAATAAATGTGGCCAGGGGGTGGGGCACCCGACGGGCAAAT
CGTTTCGTACTGAATCTGTGCGTTGCTTTCTTGCCAGCCGCAATACTGGGCTTGCTATTCATCAAAACGATAAAGTATTA
CTTATTCCACCCGCTGCCGGTTGCTATTGCATTGGTGACTGGCGGCGTGCTGATACTCTGGGCCGAGCGTCGGGAACACA
GAATTGAGGTTGAAAATGTAGATGATATGAACTGGAAGCATGCGCTGAAAATTGGCTGCGCACAGTGTCTGGCACTGATC
CCTGGCACCTCCCGTTCCGGCGCAACGATTATCGGTGGATTATTGTCCGGATTATCACGTAAAGCTGCTGCAGAATTTTC
TTTCTTTCTGGCAATCCCAATCATGTTTGCTGCCACCTTCTATGATGTCTACAAACACCGGGAATTTTTACATAGCGATG
ATCTGGGAATGTTTGTGGTGGGATCAATCGCAGCTTTCATTAGCGCGTTAATTGCGATACGCGGGTTTATACGCTATGTC
AGCCATCATGATTTCACCCTGTTTGCCTGGTACCGCATTGGTTTTGGCCTGATTGTATTGCTTACAGCCCATTTTGGCCT
GATTAACTGGTCTGCAGGTTAA

Upstream 100 bases:

>100_bases
AAAAAGCGGATGAATTCATTGAAAAAGGCGGTGAGATTTATAGAAAACTATGATCTTTCCTGGTGATTTCATTTGCTTAA
ACAATTCACATTAGGCCGCT

Downstream 100 bases:

>100_bases
TATTAAAGCCCTCTTTAGCCCTGAATCCACGGCAATCCAGCGGCTTTCCAGCCGGATTGTCGCCCGCGGTGACCACTTTC
ATCCTTATCGCCTTCAAAAC

Product: undecaprenyl pyrophosphate phosphatase

Products: NA

Alternate protein names: Bacitracin resistance protein; Undecaprenyl pyrophosphate phosphatase

Number of amino acids: Translated: 273; Mature: 273

Protein sequence:

>273_residues
MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVCWEYRARLINVARGWGTRRAN
RFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVTGGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALI
PGTSRSGATIIGGLLSGLSRKAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYV
SHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG

Sequences:

>Translated_273_residues
MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVCWEYRARLINVARGWGTRRAN
RFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVTGGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALI
PGTSRSGATIIGGLLSGLSRKAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYV
SHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG
>Mature_273_residues
MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVCWEYRARLINVARGWGTRRAN
RFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVTGGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALI
PGTSRSGATIIGGLLSGLSRKAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYV
SHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG

Specific function: Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin

COG id: COG1968

COG function: function code V; Uncharacterized bacitracin resistance protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uppP family

Homologues:

Organism=Escherichia coli, GI1789437, Length=260, Percent_Identity=48.4615384615385, Blast_Score=216, Evalue=1e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UPPP_NITEC (Q0AJJ0)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746446.1
- STRING:   Q0AJJ0
- GeneID:   4272436
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0195
- NMPDR:   fig|335283.3.peg.1685
- eggNOG:   COG1968
- HOGENOM:   HBG391969
- OMA:   PERENVT
- PhylomeDB:   Q0AJJ0
- ProtClustDB:   PRK00281
- BioCyc:   NEUT335283:NEUT_0195-MONOMER
- GO:   GO:0016311
- HAMAP:   MF_01006
- InterPro:   IPR003824
- TIGRFAMs:   TIGR00753

Pfam domain/function: PF02673 BacA

EC number: =3.6.1.27

Molecular weight: Translated: 30315; Mature: 30315

Theoretical pI: Translated: 8.62; Mature: 8.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x11fec7d4)-; HASH(0x13069a14)-; HASH(0x13069900)-; HASH(0x12eb2518)-; HASH(0x1306bc94)-; HASH(0x10951050)-; HASH(0x12198670)-;

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEECCCCCHHHHHHHHHHHHHHHHHH
WEYRARLINVARGWGTRRANRFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALIPGTSRSGATIIGGLLSGLSR
CCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG
HCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCH
>Mature Secondary Structure
MDWLILIKAFLLGIVEGLTEFLPISSTGHLILAGDLLDFNDDKAQVFTVAIQLGAILSVC
CHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECEECCCCCHHHHHHHHHHHHHHHHHH
WEYRARLINVARGWGTRRANRFVLNLCVAFLPAAILGLLFIKTIKYYLFHPLPVAIALVT
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
GGVLILWAERREHRIEVENVDDMNWKHALKIGCAQCLALIPGTSRSGATIIGGLLSGLSR
CCEEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
KAAAEFSFFLAIPIMFAATFYDVYKHREFLHSDDLGMFVVGSIAAFISALIAIRGFIRYV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SHHDFTLFAWYRIGFGLIVLLTAHFGLINWSAG
HCCCCHHHHHHHHHHHHHHHHHHHHCCEECCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA