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The map label for this gene is trpG [H]

Identifier: 114330166

GI number: 114330166

Start: 133974

End: 134576

Strand: Reverse

Name: trpG [H]

Synonym: Neut_0135

Alternate gene names: 114330166

Gene position: 134576-133974 (Counterclockwise)

Preceding gene: 114330170

Following gene: 114330165

Centisome position: 5.06

GC content: 46.1

Gene sequence:

>603_bases
ATGTTGCTGATGATTGATAATTACGATTCCTTTACCTACAACCTAGTGCAATATCTGGGTGAACTCGGTGAGGAAATTAC
GGTTGTTCGAAACGATGAAATTTCGCTAGATGCAGTTCAGCAGTTGAATCCAGCCGGCATCGTTATTTCACCAGGCCCAT
GCACACCGGATGAAGCGGGTGTTTCTATGGAATTGATCACCCGGTTTAGTGGAAAAATTCCCATATTGGGAGTGTGTCTT
GGTCATCAAAGTATCGGCCAGGCTTTCGGTGGGCGGATTGTACGTGCCGAAAAAGTCATGCATGGTAAAACATCGCCGGT
TTTTCATGATGGTCGGGGCGTTTTCCAGGGAATTGCCAGTCCGTTCATGGCAACCCGCTATCATTCACTAATTATCGAAC
CATCAAGTATACCTGACTGTCTTGCTATCTCCGCTTGGACTGAAGAAGGCGAAATTATGGGCGTGCGACACCGTACGTTG
CCAGTCGAAGGTGTGCAATTTCATCCAGAATCGGTTTTAAGTGAACATGGTCATCAGCTGCTCAAAAATTTTCTGCGCGA
ACATCATATTCAAGACCATTCATCAAAACTGTGCGAAGCGTGA

Upstream 100 bases:

>100_bases
TGGGCGAAAATACCTGAGTAGAAAGATTATGGCCATTTTCACGCATTGATTCTCTGCACAGCAATTTTTCCCCGGATATT
AAATAACCATTGTACTCGCC

Downstream 100 bases:

>100_bases
AACCACAAGCTATTCTCGCTCGAATCCTGGAGCAGCGCGAAACTCCTTATGAGGAAATGGTTGAGCTGATGCGCGCAATC
ATGTCAGGAAACGTTTCACC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 200; Mature: 200

Protein sequence:

>200_residues
MLLMIDNYDSFTYNLVQYLGELGEEITVVRNDEISLDAVQQLNPAGIVISPGPCTPDEAGVSMELITRFSGKIPILGVCL
GHQSIGQAFGGRIVRAEKVMHGKTSPVFHDGRGVFQGIASPFMATRYHSLIIEPSSIPDCLAISAWTEEGEIMGVRHRTL
PVEGVQFHPESVLSEHGHQLLKNFLREHHIQDHSSKLCEA

Sequences:

>Translated_200_residues
MLLMIDNYDSFTYNLVQYLGELGEEITVVRNDEISLDAVQQLNPAGIVISPGPCTPDEAGVSMELITRFSGKIPILGVCL
GHQSIGQAFGGRIVRAEKVMHGKTSPVFHDGRGVFQGIASPFMATRYHSLIIEPSSIPDCLAISAWTEEGEIMGVRHRTL
PVEGVQFHPESVLSEHGHQLLKNFLREHHIQDHSSKLCEA
>Mature_200_residues
MLLMIDNYDSFTYNLVQYLGELGEEITVVRNDEISLDAVQQLNPAGIVISPGPCTPDEAGVSMELITRFSGKIPILGVCL
GHQSIGQAFGGRIVRAEKVMHGKTSPVFHDGRGVFQGIASPFMATRYHSLIIEPSSIPDCLAISAWTEEGEIMGVRHRTL
PVEGVQFHPESVLSEHGHQLLKNFLREHHIQDHSSKLCEA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=181, Percent_Identity=27.6243093922652, Blast_Score=65, Evalue=3e-11,
Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.2432432432432, Blast_Score=270, Evalue=3e-74,
Organism=Escherichia coli, GI1787517, Length=188, Percent_Identity=44.1489361702128, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI1786215, Length=165, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=185, Percent_Identity=48.1081081081081, Blast_Score=199, Evalue=3e-52,
Organism=Saccharomyces cerevisiae, GI6324361, Length=215, Percent_Identity=33.4883720930233, Blast_Score=91, Evalue=1e-19,
Organism=Saccharomyces cerevisiae, GI6323873, Length=146, Percent_Identity=30.8219178082192, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI281365319, Length=145, Percent_Identity=30.3448275862069, Blast_Score=67, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22012; Mature: 22012

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLMIDNYDSFTYNLVQYLGELGEEITVVRNDEISLDAVQQLNPAGIVISPGPCTPDEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCC
VSMELITRFSGKIPILGVCLGHQSIGQAFGGRIVRAEKVMHGKTSPVFHDGRGVFQGIAS
CHHHHHHHHCCCCCEEEEEECCHHHHHHHCCEEEEHHHHHCCCCCCCEECCCHHHHHHHH
PFMATRYHSLIIEPSSIPDCLAISAWTEEGEIMGVRHRTLPVEGVQFHPESVLSEHGHQL
HHHHHHHHHEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LKNFLREHHIQDHSSKLCEA
HHHHHHHHCCCHHHHHHCCC
>Mature Secondary Structure
MLLMIDNYDSFTYNLVQYLGELGEEITVVRNDEISLDAVQQLNPAGIVISPGPCTPDEAG
CEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHCCCCCEEECCCCCCCCCCC
VSMELITRFSGKIPILGVCLGHQSIGQAFGGRIVRAEKVMHGKTSPVFHDGRGVFQGIAS
CHHHHHHHHCCCCCEEEEEECCHHHHHHHCCEEEEHHHHHCCCCCCCEECCCHHHHHHHH
PFMATRYHSLIIEPSSIPDCLAISAWTEEGEIMGVRHRTLPVEGVQFHPESVLSEHGHQL
HHHHHHHHHEEECCCCCCCCEEEEEECCCCCEEEEEECCCCCCCCEECHHHHHHHHHHHH
LKNFLREHHIQDHSSKLCEA
HHHHHHHHCCCHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]