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The map label for this gene is trpD

Identifier: 114330165

GI number: 114330165

Start: 132952

End: 133977

Strand: Reverse

Name: trpD

Synonym: Neut_0134

Alternate gene names: 114330165

Gene position: 133977-132952 (Counterclockwise)

Preceding gene: 114330166

Following gene: 114330164

Centisome position: 5.03

GC content: 49.81

Gene sequence:

>1026_bases
GTGAAACCACAAGCTATTCTCGCTCGAATCCTGGAGCAGCGCGAAACTCCTTATGAGGAAATGGTTGAGCTGATGCGCGC
AATCATGTCAGGAAACGTTTCACCGGCAATGACTGCTGCCCTGATGACGGGTTTACGCATGAAACGTGAGAGCATCGGTG
AAATTACTGCAGCGGCTCAAGTCATGCGTGAACTGGCTTTGCACATTGAAGTGGCCGATTCAGTCAATCTGGTCGATACC
TGCGGTACCGGTGGGGATGGATGCAATACCTTCAATATTTCAACAGCTTCCGCCTTTGTGGCTGCTGCTGCAGATGCACA
GGTAGCCAAACACGGCGGACGTTCTGTTTCGAGCAAAGCGGGCAGTGCAGATGTACTAGAAGCAATCGGCATCCATCTTA
ATCAAACGCCTGACCAAATTGCCCAATCCATTACCGAAGTTGGCATTGGTTTTATGTTTGCTCCTAATTTTCATCATGCC
ATGAAACATGCGGCTCCCGTTCGTCGAGAGCTGGGTGTGCGCACGTTATTCAACATCCTGGGGCCGTTAACCAATCCTGC
AGGTGCTAAAAACCAGTTGTTGGGTGTATTCAATGAAGATCTGACCGGGATATTGGCACAGGCCTTGCTCCGGCTGGGAA
GCCAGCACGCAATGATCGTCCATGGCAGCGATGGGCTGGATGAAATTACCATTTCCGGCCCAACCAAAATTGCTGAACTC
AAGGAGGGAGAAATCCGGGAATATACGGTGCAGCCGGAAGATTTCGGATTGGAACGTACCGCAATAGAATCTCTGCAGGT
AAATAGTACGGATGATGCACGAGTAATGCTTCTGTCTGTGCTGGATAATCATCCCGGACCTGCCAGAGATATTGTTCTAC
TCAATGCAGGCGCAGCAATTTATGTCGCTGGAAAAGCTGATTCCTGGGCCGAAGGGGTGGAAATTGCCCGTGACAAGCTG
GCCAGTGGTGCTGCCAAAGAAAAAATGCTGGCATTAATCAAATTCTCCAATCAGTTAACCCATTAA

Upstream 100 bases:

>100_bases
TTCATCCAGAATCGGTTTTAAGTGAACATGGTCATCAGCTGCTCAAAAATTTTCTGCGCGAACATCATATTCAAGACCAT
TCATCAAAACTGTGCGAAGC

Downstream 100 bases:

>100_bases
TTAGTTTTGCATGTCAGATATTCTTGATCGCATCCTCGCCGTAAAAAAGCAGGAGATTTCAGCTACCCAAACACAAAAAT
CACTGGATAAAATTCATGAC

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 341; Mature: 341

Protein sequence:

>341_residues
MKPQAILARILEQRETPYEEMVELMRAIMSGNVSPAMTAALMTGLRMKRESIGEITAAAQVMRELALHIEVADSVNLVDT
CGTGGDGCNTFNISTASAFVAAAADAQVAKHGGRSVSSKAGSADVLEAIGIHLNQTPDQIAQSITEVGIGFMFAPNFHHA
MKHAAPVRRELGVRTLFNILGPLTNPAGAKNQLLGVFNEDLTGILAQALLRLGSQHAMIVHGSDGLDEITISGPTKIAEL
KEGEIREYTVQPEDFGLERTAIESLQVNSTDDARVMLLSVLDNHPGPARDIVLLNAGAAIYVAGKADSWAEGVEIARDKL
ASGAAKEKMLALIKFSNQLTH

Sequences:

>Translated_341_residues
MKPQAILARILEQRETPYEEMVELMRAIMSGNVSPAMTAALMTGLRMKRESIGEITAAAQVMRELALHIEVADSVNLVDT
CGTGGDGCNTFNISTASAFVAAAADAQVAKHGGRSVSSKAGSADVLEAIGIHLNQTPDQIAQSITEVGIGFMFAPNFHHA
MKHAAPVRRELGVRTLFNILGPLTNPAGAKNQLLGVFNEDLTGILAQALLRLGSQHAMIVHGSDGLDEITISGPTKIAEL
KEGEIREYTVQPEDFGLERTAIESLQVNSTDDARVMLLSVLDNHPGPARDIVLLNAGAAIYVAGKADSWAEGVEIARDKL
ASGAAKEKMLALIKFSNQLTH
>Mature_341_residues
MKPQAILARILEQRETPYEEMVELMRAIMSGNVSPAMTAALMTGLRMKRESIGEITAAAQVMRELALHIEVADSVNLVDT
CGTGGDGCNTFNISTASAFVAAAADAQVAKHGGRSVSSKAGSADVLEAIGIHLNQTPDQIAQSITEVGIGFMFAPNFHHA
MKHAAPVRRELGVRTLFNILGPLTNPAGAKNQLLGVFNEDLTGILAQALLRLGSQHAMIVHGSDGLDEITISGPTKIAEL
KEGEIREYTVQPEDFGLERTAIESLQVNSTDDARVMLLSVLDNHPGPARDIVLLNAGAAIYVAGKADSWAEGVEIARDKL
ASGAAKEKMLALIKFSNQLTH

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=278, Percent_Identity=42.8057553956835, Blast_Score=206, Evalue=1e-54,
Organism=Saccharomyces cerevisiae, GI6320561, Length=346, Percent_Identity=30.0578034682081, Blast_Score=145, Evalue=1e-35,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_NITEC (Q0AJP9)

Other databases:

- EMBL:   CP000450
- RefSeq:   YP_746387.1
- ProteinModelPortal:   Q0AJP9
- SMR:   Q0AJP9
- STRING:   Q0AJP9
- GeneID:   4272138
- GenomeReviews:   CP000450_GR
- KEGG:   net:Neut_0134
- NMPDR:   fig|335283.3.peg.467
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   LGVYSPE
- PhylomeDB:   Q0AJP9
- ProtClustDB:   PRK00188
- BioCyc:   NEUT335283:NEUT_0134-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36238; Mature: 36238

Theoretical pI: Translated: 5.38; Mature: 5.38

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPQAILARILEQRETPYEEMVELMRAIMSGNVSPAMTAALMTGLRMKRESIGEITAAAQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRELALHIEVADSVNLVDTCGTGGDGCNTFNISTASAFVAAAADAQVAKHGGRSVSSKA
HHHHHHHHEEECCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
GSADVLEAIGIHLNQTPDQIAQSITEVGIGFMFAPNFHHAMKHAAPVRRELGVRTLFNIL
CCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAKNQLLGVFNEDLTGILAQALLRLGSQHAMIVHGSDGLDEITISGPTKIAEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHC
KEGEIREYTVQPEDFGLERTAIESLQVNSTDDARVMLLSVLDNHPGPARDIVLLNAGAAI
CCCCCEEEEECCHHCCCHHHHHHHEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCEE
YVAGKADSWAEGVEIARDKLASGAAKEKMLALIKFSNQLTH
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKPQAILARILEQRETPYEEMVELMRAIMSGNVSPAMTAALMTGLRMKRESIGEITAAAQ
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
VMRELALHIEVADSVNLVDTCGTGGDGCNTFNISTASAFVAAAADAQVAKHGGRSVSSKA
HHHHHHHHEEECCCCCEEECCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCCCCCCCCCC
GSADVLEAIGIHLNQTPDQIAQSITEVGIGFMFAPNFHHAMKHAAPVRRELGVRTLFNIL
CCHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHH
GPLTNPAGAKNQLLGVFNEDLTGILAQALLRLGSQHAMIVHGSDGLDEITISGPTKIAEL
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCEEEECCCCHHHHC
KEGEIREYTVQPEDFGLERTAIESLQVNSTDDARVMLLSVLDNHPGPARDIVLLNAGAAI
CCCCCEEEEECCHHCCCHHHHHHHEECCCCCCHHHHHHHHHCCCCCCCCEEEEEECCCEE
YVAGKADSWAEGVEIARDKLASGAAKEKMLALIKFSNQLTH
EEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA