Click here to switch to the map view.

The map label for this gene is ccdA [H]

Identifier: 114330086

GI number: 114330086

Start: 55436

End: 56182

Strand: Reverse

Name: ccdA [H]

Synonym: Neut_0054

Alternate gene names: 114330086

Gene position: 56182-55436 (Counterclockwise)

Preceding gene: 114330087

Following gene: 114330085

Centisome position: 2.11

GC content: 53.82

Gene sequence:

>747_bases
ATGCTTGAATTAACTGTCATTGGGCTATTAACGGCGTTTTTCGCCGGTATTGCTTCCTTCCTATCGCCCTGTGTTTTACC
GCTCGTGCCAGGTTACCTCTCCTATATTGCGGGCGATTCGGTTCAGTCCAGTGCCTCTCATATCGAAGCACGTGTGGCTC
GCTGGCGAGCATTGGGCCTTAGTGCGTGTTTCGTTGCTGGCTTCTCCATGGTGTTCCTGATTTTAGGAGCCAGCATTACT
GTAATCGGGCGTTTGTTTTTATCGTATCGCTACGAACTGAATATTGCCGCGGGCGGCGTTATTGTCGTCGCTGGCCTGAT
GGTTATGGGCGTTATACGTGCCCCGCTATGGATGCAACGTTACTACCGCTTTGAACCGCAGGGCGGCGGCGGTAAGCCTT
GGTCGGCGACCGTGCTTGGTATGGCGTTCGGCTTCGGTTGGACGCCATGTATTGGTCCCGTGCTTGGCGGTATTTTGATA
CTCGGCGCCACGTCTGAGAGTCTCGGGCAGGGAATATTGCTTTTGGGTATTTACGCACTGGGCTTAGGTGTGCCGTTCTT
GCTTTCCGCGTACTTCATGACGCCGTTTATGCGTCGAATAGGTTCATTGCGCCGAACGGGTCGCTACCTTCAGATAATCA
CCGGCGCGATTCTGGTGCTGATGGGTATTGCGGTAGCAAGTGGGCAGTTGGTGCGTTTTGCGATTTGGTTACTGAGGACG
TTTCCTGCGCTTGGGGCAATTGGGTAG

Upstream 100 bases:

>100_bases
GTCGAAGCCCTAATTGATGGCGCACTGCTGCGCCCCTCTATTCGAGATTCAAAGTGATGAGATATAAGAATAAAGCAGAC
TACCTACTGGGAATGATGCG

Downstream 100 bases:

>100_bases
TTGCGTGGTTTTGCGCGTAATAAATAAGCGAAGAGGGACACCACATGACATCTTTGTAATGACGGCGTCATCTTCGTGAC
AGACCGCTATCAGTATAGTG

Product: cytochrome c biogenesis protein, transmembrane region

Products: DsbDoxidized; DsbGreduced [C]

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MLELTVIGLLTAFFAGIASFLSPCVLPLVPGYLSYIAGDSVQSSASHIEARVARWRALGLSACFVAGFSMVFLILGASIT
VIGRLFLSYRYELNIAAGGVIVVAGLMVMGVIRAPLWMQRYYRFEPQGGGGKPWSATVLGMAFGFGWTPCIGPVLGGILI
LGATSESLGQGILLLGIYALGLGVPFLLSAYFMTPFMRRIGSLRRTGRYLQIITGAILVLMGIAVASGQLVRFAIWLLRT
FPALGAIG

Sequences:

>Translated_248_residues
MLELTVIGLLTAFFAGIASFLSPCVLPLVPGYLSYIAGDSVQSSASHIEARVARWRALGLSACFVAGFSMVFLILGASIT
VIGRLFLSYRYELNIAAGGVIVVAGLMVMGVIRAPLWMQRYYRFEPQGGGGKPWSATVLGMAFGFGWTPCIGPVLGGILI
LGATSESLGQGILLLGIYALGLGVPFLLSAYFMTPFMRRIGSLRRTGRYLQIITGAILVLMGIAVASGQLVRFAIWLLRT
FPALGAIG
>Mature_248_residues
MLELTVIGLLTAFFAGIASFLSPCVLPLVPGYLSYIAGDSVQSSASHIEARVARWRALGLSACFVAGFSMVFLILGASIT
VIGRLFLSYRYELNIAAGGVIVVAGLMVMGVIRAPLWMQRYYRFEPQGGGGKPWSATVLGMAFGFGWTPCIGPVLGGILI
LGATSESLGQGILLLGIYALGLGVPFLLSAYFMTPFMRRIGSLRRTGRYLQIITGAILVLMGIAVASGQLVRFAIWLLRT
FPALGAIG

Specific function: Required for cytochrome c synthesis and stage V of sporulation. Might transfer reducing equivalents across the cytoplasmic membrane, promoting efficient disulfide bond isomerization of proteins localized on the outer surface of the membrane or in the spor

COG id: COG0785

COG function: function code O; Cytochrome c biogenesis protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbD family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003834 [H]

Pfam domain/function: PF02683 DsbD [H]

EC number: 1.8.1.8 [C]

Molecular weight: Translated: 26332; Mature: 26332

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHCCCC
>Mature Secondary Structure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HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DsbGoxidized; DsbDreduced/thiol:disulfide reductase [C]

Specific reaction: DsbDreduced/thiol:disulfide reductase + DsbCoxidized = DsbDoxidized + DsbCreduced DsbGoxidized + DsbDreduced/thiol:disulfide reductase = DsbGreduced + DsbDoxidized [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]