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The map label for this gene is prc [H]

Identifier: 113970013

GI number: 113970013

Start: 1973726

End: 1975777

Strand: Direct

Name: prc [H]

Synonym: Shewmr4_1673

Alternate gene names: 113970013

Gene position: 1973726-1975777 (Clockwise)

Preceding gene: 113970012

Following gene: 113970014

Centisome position: 41.94

GC content: 47.76

Gene sequence:

>2052_bases
ATGCGAAAACTCACTTTGGCTACATCCATTGCCACTGTTTTTGTCGGATTCTCGGCTTGGGCTGTCCCCCCTACGATTCA
AATCAGCGAGTTACCCACTCTCAAGCAGGAAGCGCAGCATAAAGTGGCGAGTAAGCGAGTGACGGATTTATACACTCGTT
CCCACTATCATAGATTTGCATTAGATGATGCGTTTTCTGCTCAGATTTTTGACCGCTACCTGCAGCAACTCGACTACCGT
CGTAATGTGCTGACGCAAGCCGATGTCGACAGCTTCAAACCTTATGTTAATCAGTTTGACGATATGCTGAGCTCGGGTGA
ACTCGAGCCTGCTTATAAGATGTTTGATTTGGTTCAGAAACGTCGCTACGAAGGTTTTGTATACGCACTCTCTCTGCTCG
ACAAAGAGATGGACTTTACCGTTCCGGGTGATGCCTACGAATACGATAGAGAAGATGTTGCATGGCCAAAAGATCAAGCC
GAAATCAACGAATTATGGCGTCAACGTGTTAAATACGATGCGCTGAACCTGAAACTTACTGGCAAGAAATGGCCTGAAAT
CGTTGATATTCTGCAAAAACGCTACAACAACGCCATTAAACGTCTGACTCAGACCAATAGCGAAGATGTGTTCCAAGCGG
TGATGAATGCGTTCTCCCGTAGCATCGAGCCACACACTAGCTATTTATCGCCCCGTAATGCTGAACGTTTCCAAATGGAA
ATGAACTTAAGCCTCGAGGGGATTGGTGCGCAGTTACAGCTCGAAGACGATTACACTGTGATTAAGAGTTTAATCGCGGG
CGGTCCTGCGGCTAGTAGTGAAAAACTGTCGCCTGAAGATAAGATCGTCGGCGTCGGTCAAGAAGGCGGTGAGATTGTTG
ATGTAATCGGCTGGCGATTGGACGATGTGGTCGATCTGATCAAAGGGCCTAAGGGCAGTAAAGTCGTTCTGCAGATTTTA
CCTAAGAAGGGCGGCTCTAACGCTAAGCCGTTTAATCTGACCTTAGTGCGCGACAAAATTCGTTTAGAAGACCGTGCCGC
GACCTCAAAGATCATCGAGCCAAAAGACGGTGAATACGCCAACCGTAAAGTGGGTGTGATTCAAATTCCTGGTTTCTATA
TGAACTTATCCCAGGACGTCGAAAAAGAATTAGTGAAGTTAAACGAAGCCAAGGTTGAAGGCGTCGTCATCGATTTACGT
GGTAATGGCGGCGGTGCGTTGACCGAAGCCGTGTTACTGACGGGACTCTTTATCGATATGGGCCCTGTGGTGCAAGTACG
TGACGCCGATGGTCGAGTGTCTGCCCACCGTGATAACGATGGCAAGACGACCTACGCTGGTCCGTTAACCATTATGGTTG
ACCGTTACAGTGCATCAGCTTCTGAAATTTTTGCCGCCGCGTTGCAAGATTACGACCGTGCGCTGATTGTCGGTGAGTCA
AGCTTTGGTAAAGGCACTGTGCAGCAGCATAAGAGCCTTGGTCGAATCTACGACATGTACGAGAAGCCGATTGGCCACGT
GCAGTACACGATTCAAAAGTTCTACCGTATCAACGGTGGCAGCACTCAGCTCAAAGGCGTAACCCCGAACATTGCTTACC
CAAGTGCGTTAGAGCCGGGTGAATACGGTGAAGCGGAAGAGAAGAATGCTTTACCTTGGGATAAAGTGCCGATGGCGCAA
TACGGCACCCTAAACGATATCACCCCTGAGTTGGTGGCGAGTTTAGATAAAAAGCACCTTGCCCGTATTCAGAACAATGT
CGAGTTTAACTATATCAATCAAGATATTGCCGACTTTAAAAAGCATCATAAAGAGAAAACAGTCTCCTTAGTTGAAAGTG
AGCGCATTGCCTCACGTGAAGCCGATGAGAAGAAAGTCCTCGATAGAACCAACGAGCGTCGTGTTGCCCATGGTTTAGCC
GCGGTTAAATCGATGGAAGACATTAAAGACAAAGACGACATTGAAGCACCGGATGCCTTCTTAGACGAAACGGCCTATAT
CACCTTAGATATGGCGGATGCAAAAAAGCTGGCTAACGCTGGCACTAAATAG

Upstream 100 bases:

>100_bases
AAAGAGGACATTCATGTTCAGCTAGATAGCGGCTTAACGGTAAAAGTGAAAGCGGAACATATCCTGCTGTAATTATTTAA
TCAAACGGAGTAACTTGTTG

Downstream 100 bases:

>100_bases
GCGGTTATTGCGCCTGTTTACCGTATCTTAAAACGCGCTTATGGCGCGTTTTTCTTATTTAGAACAGTGTTAAAGGGAAC
GACATGACACAAGCACAAGC

Product: carboxy-terminal protease

Products: NA

Alternate protein names: C-terminal-processing peptidase; PRC protein; Protease Re [H]

Number of amino acids: Translated: 683; Mature: 683

Protein sequence:

>683_residues
MRKLTLATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFALDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYVNQFDDMLSSGELEPAYKMFDLVQKRRYEGFVYALSLLDKEMDFTVPGDAYEYDREDVAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAASSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKIIEPKDGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGVVIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDADGRVSAHRDNDGKTTYAGPLTIMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPMAQ
YGTLNDITPELVASLDKKHLARIQNNVEFNYINQDIADFKKHHKEKTVSLVESERIASREADEKKVLDRTNERRVAHGLA
AVKSMEDIKDKDDIEAPDAFLDETAYITLDMADAKKLANAGTK

Sequences:

>Translated_683_residues
MRKLTLATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFALDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYVNQFDDMLSSGELEPAYKMFDLVQKRRYEGFVYALSLLDKEMDFTVPGDAYEYDREDVAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAASSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKIIEPKDGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGVVIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDADGRVSAHRDNDGKTTYAGPLTIMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPMAQ
YGTLNDITPELVASLDKKHLARIQNNVEFNYINQDIADFKKHHKEKTVSLVESERIASREADEKKVLDRTNERRVAHGLA
AVKSMEDIKDKDDIEAPDAFLDETAYITLDMADAKKLANAGTK
>Mature_683_residues
MRKLTLATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFALDDAFSAQIFDRYLQQLDYR
RNVLTQADVDSFKPYVNQFDDMLSSGELEPAYKMFDLVQKRRYEGFVYALSLLDKEMDFTVPGDAYEYDREDVAWPKDQA
EINELWRQRVKYDALNLKLTGKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQME
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAASSEKLSPEDKIVGVGQEGGEIVDVIGWRLDDVVDLIKGPKGSKVVLQIL
PKKGGSNAKPFNLTLVRDKIRLEDRAATSKIIEPKDGEYANRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGVVIDLR
GNGGGALTEAVLLTGLFIDMGPVVQVRDADGRVSAHRDNDGKTTYAGPLTIMVDRYSASASEIFAAALQDYDRALIVGES
SFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEPGEYGEAEEKNALPWDKVPMAQ
YGTLNDITPELVASLDKKHLARIQNNVEFNYINQDIADFKKHHKEKTVSLVESERIASREADEKKVLDRTNERRVAHGLA
AVKSMEDIKDKDDIEAPDAFLDETAYITLDMADAKKLANAGTK

Specific function: Involved in the cleavage of a C-terminal peptide of 11 residues from the precursor form of penicillin-binding protein 3 (PBP3). May be involved in protection of the bacterium from thermal and osmotic stresses [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Periplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=678, Percent_Identity=53.3923303834808, Blast_Score=677, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447
- InterPro:   IPR020992 [H]

Pfam domain/function: PF11818 DUF3340; PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 76598; Mature: 76598

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKLTLATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFA
CCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDAFSAQIFDRYLQQLDYRRNVLTQADVDSFKPYVNQFDDMLSSGELEPAYKMFDLVQK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RRYEGFVYALSLLDKEMDFTVPGDAYEYDREDVAWPKDQAEINELWRQRVKYDALNLKLT
HHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
GKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQME
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEE
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAASSEKLSPEDKIVGVGQEGGEIVDVIGWRL
ECCEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCH
DDVVDLIKGPKGSKVVLQILPKKGGSNAKPFNLTLVRDKIRLEDRAATSKIIEPKDGEYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCC
NRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGVVIDLRGNGGGALTEAVLLTGLFIDM
CCEEEEEECCCCEECCHHHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCC
GPVVQVRDADGRVSAHRDNDGKTTYAGPLTIMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCEEECCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
SFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEPG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCEEECCCCCCCCCCCCCCCC
EYGEAEEKNALPWDKVPMAQYGTLNDITPELVASLDKKHLARIQNNVEFNYINQDIADFK
CCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHH
KHHKEKTVSLVESERIASREADEKKVLDRTNERRVAHGLAAVKSMEDIKDKDDIEAPDAF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LDETAYITLDMADAKKLANAGTK
HCCCEEEEEEHHHHHHHHCCCCC
>Mature Secondary Structure
MRKLTLATSIATVFVGFSAWAVPPTIQISELPTLKQEAQHKVASKRVTDLYTRSHYHRFA
CCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LDDAFSAQIFDRYLQQLDYRRNVLTQADVDSFKPYVNQFDDMLSSGELEPAYKMFDLVQK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
RRYEGFVYALSLLDKEMDFTVPGDAYEYDREDVAWPKDQAEINELWRQRVKYDALNLKLT
HHHCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCEEEEEEC
GKKWPEIVDILQKRYNNAIKRLTQTNSEDVFQAVMNAFSRSIEPHTSYLSPRNAERFQME
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHCCCCCCCCEEEE
MNLSLEGIGAQLQLEDDYTVIKSLIAGGPAASSEKLSPEDKIVGVGQEGGEIVDVIGWRL
ECCEEECCCCEEEECCCHHHHHHHHCCCCCCCCCCCCCCCCEEECCCCCCCCHHHHHCCH
DDVVDLIKGPKGSKVVLQILPKKGGSNAKPFNLTLVRDKIRLEDRAATSKIIEPKDGEYA
HHHHHHHCCCCCCEEEEEEECCCCCCCCCCEEEEEEECHHHHHHHHHHHHCCCCCCCCCC
NRKVGVIQIPGFYMNLSQDVEKELVKLNEAKVEGVVIDLRGNGGGALTEAVLLTGLFIDM
CCEEEEEECCCCEECCHHHHHHHHHHHHCCEEEEEEEEEECCCCHHHHHHHHHHHHHHCC
GPVVQVRDADGRVSAHRDNDGKTTYAGPLTIMVDRYSASASEIFAAALQDYDRALIVGES
CCEEEEECCCCCEEECCCCCCCEEECCCEEEEEECCCCCHHHHHHHHHHHCCCEEEEECC
SFGKGTVQQHKSLGRIYDMYEKPIGHVQYTIQKFYRINGGSTQLKGVTPNIAYPSALEPG
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHEECCCCEEECCCCCCCCCCCCCCCC
EYGEAEEKNALPWDKVPMAQYGTLNDITPELVASLDKKHLARIQNNVEFNYINQDIADFK
CCCCCCCCCCCCCCCCCCHHCCCCCCCCHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHH
KHHKEKTVSLVESERIASREADEKKVLDRTNERRVAHGLAAVKSMEDIKDKDDIEAPDAF
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
LDETAYITLDMADAKKLANAGTK
HCCCEEEEEEHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1856173; 1729701; 9097040; 9278503; 1447154; 10049386; 7499412; 8576225 [H]