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The map label for this gene is pepN [H]

Identifier: 113970014

GI number: 113970014

Start: 1975861

End: 1978410

Strand: Direct

Name: pepN [H]

Synonym: Shewmr4_1674

Alternate gene names: 113970014

Gene position: 1975861-1978410 (Clockwise)

Preceding gene: 113970013

Following gene: 113970015

Centisome position: 41.98

GC content: 48.08

Gene sequence:

>2550_bases
ATGACACAAGCACAAGCAAAATATCTTAAAGATTATCAAGCTCCCCAGTTCACGATCGAAACCATTGATTTAGATTTTAA
TCTCGATGGTAAAAACACCCTGGTTAAAGCCGTTAGCAAAGTCAAACGCACTTCATCTCACACCAATCCCTTAGTGCTAG
ATGGTGAAAGTTTGACCTTAGTGAGTGTGGCCATTGATGGACAAGCGGCGACGTATCACGCGAGTGAAGGGCTGTTGTCC
ATCGAGACATCGCTGAATGAATTTGAGTTGACCATCATCACCCAACTCGATCCCGAGGCTAACTCAAGCCTCGAAGGGCT
ATATATGTCCGACGGCGCCTACTGTACTCAGTGCGAAGCCGAAGGCTTTAGACGCATCACTTATTTTCTCGACCGCCCCG
ATGTGTTAGCCAAATACACAGTGCGAATCGAAGCCGATAAGCTGGCGTTTCCGTTCCTGCTTAGCAACGGTAACTTGATT
GAGAAAGGCGAGCTCGATGGTGGCCGCCATTACGTGCGCTGGCAGGATCCCTTCCCAAAACCCGCCTATCTGTTTGCTTT
AGTCGCTGGCGATTTCGATCTGCTACAGGATGAGTTTATCACCCGCAGTCATCGCAAAGTGGTACTGCAGGTGTTTGTCG
ATAAAGGTAATTTACACAAAGCACACCATGCGATGGCGTCCCTGAAAAAGTCTATGGCCTGGGATGAATCTCGTTTTGAC
CTAGAATACGACTTAGATATCTACATGATAGTCGCGGTCGACTTCTTCAATATGGGGGCGATGGAAAACAAAGGCTTAAA
TATCTTCAACACCAAGTATGTGTTGGCAGATACCTTGACCGCAACCGACGAGGATTACCACGGCATTGAATCTGTGGTCG
GCCATGAGTACTTCCATAACTGGACGGGTAACCGCGTGACTTGCCGTGACTGGTTCCAATTAAGCCTCAAGGAAGGCTTG
ACAGTGTTTCGCGATCAAGAGTTTAGTTCGGATTTAGGTTCGCGTGCTGTGAACCGAATTCACGCGATTAAAGTCATCAA
AAACCAGCAGTTTGCTGAAGACTCAGGCCCAATGGCGCATCCGATCCGCCCCGAGTCTGTGATTGAGATGAATAATTTTT
ATACTGTTACTGTGTATAACAAGGGCGCTGAAGTTATTCGCATGATGCACACCCTGTTGGGTGAAGCCCATTTCCAAGCG
GGGATGAAGTTATACTTCAAACGTCACGATGGCCAAGCCGTGACTTGCGATGATTTTGTCGCGGCGATGGAAGATGCCAG
TGGAATCGATTTAACGCAATTCCGTCTCTGGTATAGCCAAGCGGGCACGCCAATTGTCACCGCAAGCGACAGTTTTAATG
CTGACACAGGGACTTATCAGTTAACCCTCAAACAAACGTTAGCTGGTTGTGCTTCACCCTTGCATATCCCCTTTAGCTTA
GAGCTGTTAGATGAGAAAGGGCAGTCACTGGTAAATCAAGTGCTTGATTTTACTCAAGCAGAGCAAGTTTTTACATTTGA
AGGCATGCGCCATAAACCCGTGGCATCCTTACTACAGGATTTCTCTGCACCGGTTAAATTACATTATCCCTTTGAAATCG
ATCAGCTTGTGCATTTGATGCGCTTTGCCTCGAGTGAAGTGGCGCGTTGGGAGGCGTCGGTTACGCTCGTGAGCCAAGCG
ATTTGGCAAAATGTGGCGCATTTACAGCAACATCACACCATGACCTTAGATGAGAGAGTGAAGGACAGCTTTAAAGGCGC
CTTACTCGATGAGCAGTTAGATCAGGCGCTGATGGCGGAAATGTTAGCCATACCATCGGCCTCAGCGTTGATTGAACAAA
CCGACACGGTCGATTTAGATGCCTTAGCTTTAGCCCGTGAATTTGTGCTCACAGAGCTTGCCGCCTATTGTGAAGATGAA
TTAACGGCGCTGTATCGCTCATTGGTAAACCGTGATTGCACAAAAGCGCGAGCGCTGAAAAACCAATGTCTTAACTGGTT
GAGCCGAGTCAGTAGCGAGGCCGAAAGCTTTGTGGTTGAGCAGTTTGAGAAGGCTGCCAATATGACCGACTCACTCGGCG
CATTAAGTGCGGCGAATGTCGGTTCGCTACCTTGCCGCGAACATTTGATGGCAATGTTTGAAGCCCGCTGGCGCGATACG
CCGCTGGTGATGGACAAATGGTTCATGCTGCAGGCTACCCATGATGTGGAAGGGGTGATTGATAGCTTGCGTCAATTACA
ACAACACGCGAGCTTTAGCATGAGCAATCCTAACCGCGTACGTTCACTGATTGGCAGTTTCGCAGCGGGGAATATTTATC
AATTCCACCGCGCCGATGGCAAAGGTTATGAGTTTTTAACTGAATGTCTTATCAGCTTAAATAAACTCAACCCGCAGGTT
GCGGCGCGTATGGTGACGCCACTCATCCAATTTAGTAAGTTTGATGAGGCGCGCCAAGCCAAGATCAAGGCTTGTTTAAC
GCGATTGTTGGCACTGCCTGAACTGTCGAAAGATTTATTCGAGAAAGTATCTAAGGCATTAGCACAGTAG

Upstream 100 bases:

>100_bases
ACGCTGGCACTAAATAGGCGGTTATTGCGCCTGTTTACCGTATCTTAAAACGCGCTTATGGCGCGTTTTTCTTATTTAGA
ACAGTGTTAAAGGGAACGAC

Downstream 100 bases:

>100_bases
CTATGAAGAGGGCAGCATTATGCTGCCCTCATTCTTCCAAGCAGTTATTGAGCAGTTAGAGTCAAATTGAAGGCCATGCA
CCCTAGTCATACTATTTAAC

Product: aminopeptidase N

Products: NA

Alternate protein names: Alpha-aminoacylpeptide hydrolase [H]

Number of amino acids: Translated: 849; Mature: 848

Protein sequence:

>849_residues
MTQAQAKYLKDYQAPQFTIETIDLDFNLDGKNTLVKAVSKVKRTSSHTNPLVLDGESLTLVSVAIDGQAATYHASEGLLS
IETSLNEFELTIITQLDPEANSSLEGLYMSDGAYCTQCEAEGFRRITYFLDRPDVLAKYTVRIEADKLAFPFLLSNGNLI
EKGELDGGRHYVRWQDPFPKPAYLFALVAGDFDLLQDEFITRSHRKVVLQVFVDKGNLHKAHHAMASLKKSMAWDESRFD
LEYDLDIYMIVAVDFFNMGAMENKGLNIFNTKYVLADTLTATDEDYHGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGL
TVFRDQEFSSDLGSRAVNRIHAIKVIKNQQFAEDSGPMAHPIRPESVIEMNNFYTVTVYNKGAEVIRMMHTLLGEAHFQA
GMKLYFKRHDGQAVTCDDFVAAMEDASGIDLTQFRLWYSQAGTPIVTASDSFNADTGTYQLTLKQTLAGCASPLHIPFSL
ELLDEKGQSLVNQVLDFTQAEQVFTFEGMRHKPVASLLQDFSAPVKLHYPFEIDQLVHLMRFASSEVARWEASVTLVSQA
IWQNVAHLQQHHTMTLDERVKDSFKGALLDEQLDQALMAEMLAIPSASALIEQTDTVDLDALALAREFVLTELAAYCEDE
LTALYRSLVNRDCTKARALKNQCLNWLSRVSSEAESFVVEQFEKAANMTDSLGALSAANVGSLPCREHLMAMFEARWRDT
PLVMDKWFMLQATHDVEGVIDSLRQLQQHASFSMSNPNRVRSLIGSFAAGNIYQFHRADGKGYEFLTECLISLNKLNPQV
AARMVTPLIQFSKFDEARQAKIKACLTRLLALPELSKDLFEKVSKALAQ

Sequences:

>Translated_849_residues
MTQAQAKYLKDYQAPQFTIETIDLDFNLDGKNTLVKAVSKVKRTSSHTNPLVLDGESLTLVSVAIDGQAATYHASEGLLS
IETSLNEFELTIITQLDPEANSSLEGLYMSDGAYCTQCEAEGFRRITYFLDRPDVLAKYTVRIEADKLAFPFLLSNGNLI
EKGELDGGRHYVRWQDPFPKPAYLFALVAGDFDLLQDEFITRSHRKVVLQVFVDKGNLHKAHHAMASLKKSMAWDESRFD
LEYDLDIYMIVAVDFFNMGAMENKGLNIFNTKYVLADTLTATDEDYHGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGL
TVFRDQEFSSDLGSRAVNRIHAIKVIKNQQFAEDSGPMAHPIRPESVIEMNNFYTVTVYNKGAEVIRMMHTLLGEAHFQA
GMKLYFKRHDGQAVTCDDFVAAMEDASGIDLTQFRLWYSQAGTPIVTASDSFNADTGTYQLTLKQTLAGCASPLHIPFSL
ELLDEKGQSLVNQVLDFTQAEQVFTFEGMRHKPVASLLQDFSAPVKLHYPFEIDQLVHLMRFASSEVARWEASVTLVSQA
IWQNVAHLQQHHTMTLDERVKDSFKGALLDEQLDQALMAEMLAIPSASALIEQTDTVDLDALALAREFVLTELAAYCEDE
LTALYRSLVNRDCTKARALKNQCLNWLSRVSSEAESFVVEQFEKAANMTDSLGALSAANVGSLPCREHLMAMFEARWRDT
PLVMDKWFMLQATHDVEGVIDSLRQLQQHASFSMSNPNRVRSLIGSFAAGNIYQFHRADGKGYEFLTECLISLNKLNPQV
AARMVTPLIQFSKFDEARQAKIKACLTRLLALPELSKDLFEKVSKALAQ
>Mature_848_residues
TQAQAKYLKDYQAPQFTIETIDLDFNLDGKNTLVKAVSKVKRTSSHTNPLVLDGESLTLVSVAIDGQAATYHASEGLLSI
ETSLNEFELTIITQLDPEANSSLEGLYMSDGAYCTQCEAEGFRRITYFLDRPDVLAKYTVRIEADKLAFPFLLSNGNLIE
KGELDGGRHYVRWQDPFPKPAYLFALVAGDFDLLQDEFITRSHRKVVLQVFVDKGNLHKAHHAMASLKKSMAWDESRFDL
EYDLDIYMIVAVDFFNMGAMENKGLNIFNTKYVLADTLTATDEDYHGIESVVGHEYFHNWTGNRVTCRDWFQLSLKEGLT
VFRDQEFSSDLGSRAVNRIHAIKVIKNQQFAEDSGPMAHPIRPESVIEMNNFYTVTVYNKGAEVIRMMHTLLGEAHFQAG
MKLYFKRHDGQAVTCDDFVAAMEDASGIDLTQFRLWYSQAGTPIVTASDSFNADTGTYQLTLKQTLAGCASPLHIPFSLE
LLDEKGQSLVNQVLDFTQAEQVFTFEGMRHKPVASLLQDFSAPVKLHYPFEIDQLVHLMRFASSEVARWEASVTLVSQAI
WQNVAHLQQHHTMTLDERVKDSFKGALLDEQLDQALMAEMLAIPSASALIEQTDTVDLDALALAREFVLTELAAYCEDEL
TALYRSLVNRDCTKARALKNQCLNWLSRVSSEAESFVVEQFEKAANMTDSLGALSAANVGSLPCREHLMAMFEARWRDTP
LVMDKWFMLQATHDVEGVIDSLRQLQQHASFSMSNPNRVRSLIGSFAAGNIYQFHRADGKGYEFLTECLISLNKLNPQVA
ARMVTPLIQFSKFDEARQAKIKACLTRLLALPELSKDLFEKVSKALAQ

Specific function: Aminopeptidase N is involved in the degradation of intracellular peptides generated by protein breakdown during normal growth as well as in response to nutrient starvation [H]

COG id: COG0308

COG function: function code E; Aminopeptidase N

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M1 family [H]

Homologues:

Organism=Homo sapiens, GI158937236, Length=480, Percent_Identity=25, Blast_Score=134, Evalue=5e-31,
Organism=Homo sapiens, GI310123622, Length=418, Percent_Identity=25.1196172248804, Blast_Score=114, Evalue=3e-25,
Organism=Homo sapiens, GI310133497, Length=353, Percent_Identity=26.628895184136, Blast_Score=108, Evalue=2e-23,
Organism=Homo sapiens, GI132814467, Length=371, Percent_Identity=26.4150943396226, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI61742777, Length=391, Percent_Identity=24.2966751918159, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI61742775, Length=391, Percent_Identity=24.2966751918159, Blast_Score=103, Evalue=8e-22,
Organism=Homo sapiens, GI194306629, Length=311, Percent_Identity=27.9742765273312, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI11641261, Length=311, Percent_Identity=27.9742765273312, Blast_Score=101, Evalue=3e-21,
Organism=Homo sapiens, GI194239713, Length=313, Percent_Identity=26.517571884984, Blast_Score=88, Evalue=3e-17,
Organism=Homo sapiens, GI94818901, Length=423, Percent_Identity=24.822695035461, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4505029, Length=401, Percent_Identity=25.1870324189526, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI94818891, Length=423, Percent_Identity=24.822695035461, Blast_Score=86, Evalue=2e-16,
Organism=Homo sapiens, GI157266300, Length=363, Percent_Identity=23.9669421487603, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI7019561, Length=272, Percent_Identity=22.7941176470588, Blast_Score=68, Evalue=3e-11,
Organism=Escherichia coli, GI1787163, Length=867, Percent_Identity=56.9780853517878, Blast_Score=984, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71989071, Length=514, Percent_Identity=25.0972762645914, Blast_Score=121, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71989076, Length=514, Percent_Identity=25.0972762645914, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17569221, Length=375, Percent_Identity=25.6, Blast_Score=105, Evalue=7e-23,
Organism=Caenorhabditis elegans, GI17569225, Length=443, Percent_Identity=24.3792325056433, Blast_Score=96, Evalue=8e-20,
Organism=Caenorhabditis elegans, GI193206928, Length=391, Percent_Identity=24.5524296675192, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI193206926, Length=391, Percent_Identity=24.5524296675192, Blast_Score=91, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI115533278, Length=358, Percent_Identity=24.8603351955307, Blast_Score=90, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI115533276, Length=358, Percent_Identity=24.8603351955307, Blast_Score=90, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17544504, Length=442, Percent_Identity=23.5294117647059, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI133903840, Length=484, Percent_Identity=22.1074380165289, Blast_Score=77, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17565628, Length=313, Percent_Identity=26.1980830670927, Blast_Score=77, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71990873, Length=331, Percent_Identity=22.9607250755287, Blast_Score=70, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI9755335, Length=355, Percent_Identity=26.1971830985915, Blast_Score=110, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6321837, Length=441, Percent_Identity=24.2630385487528, Blast_Score=105, Evalue=4e-23,
Organism=Drosophila melanogaster, GI24655257, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24655252, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=2e-34,
Organism=Drosophila melanogaster, GI24655274, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24655260, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24655265, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24655268, Length=477, Percent_Identity=28.9308176100629, Blast_Score=144, Evalue=3e-34,
Organism=Drosophila melanogaster, GI24646514, Length=390, Percent_Identity=29.4871794871795, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI24646518, Length=368, Percent_Identity=29.0760869565217, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24646516, Length=353, Percent_Identity=29.4617563739377, Blast_Score=133, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24651025, Length=484, Percent_Identity=23.7603305785124, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24651023, Length=484, Percent_Identity=23.7603305785124, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24651021, Length=484, Percent_Identity=23.7603305785124, Blast_Score=103, Evalue=5e-22,
Organism=Drosophila melanogaster, GI21358341, Length=496, Percent_Identity=23.1854838709677, Blast_Score=96, Evalue=1e-19,
Organism=Drosophila melanogaster, GI221379089, Length=359, Percent_Identity=25.6267409470752, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24648786, Length=397, Percent_Identity=26.1964735516373, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24646510, Length=281, Percent_Identity=25.9786476868327, Blast_Score=91, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24646512, Length=281, Percent_Identity=25.9786476868327, Blast_Score=90, Evalue=5e-18,
Organism=Drosophila melanogaster, GI45550850, Length=401, Percent_Identity=24.9376558603491, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24650973, Length=401, Percent_Identity=24.9376558603491, Blast_Score=88, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24651016, Length=250, Percent_Identity=28.8, Blast_Score=87, Evalue=5e-17,
Organism=Drosophila melanogaster, GI28571901, Length=402, Percent_Identity=23.6318407960199, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI161078673, Length=402, Percent_Identity=23.6318407960199, Blast_Score=82, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24648790, Length=319, Percent_Identity=24.4514106583072, Blast_Score=77, Evalue=6e-14,
Organism=Drosophila melanogaster, GI28571792, Length=370, Percent_Identity=24.5945945945946, Blast_Score=74, Evalue=5e-13,
Organism=Drosophila melanogaster, GI221330574, Length=301, Percent_Identity=25.5813953488372, Blast_Score=70, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001930
- InterPro:   IPR014782
- InterPro:   IPR012779 [H]

Pfam domain/function: PF01433 Peptidase_M1 [H]

EC number: =3.4.11.2 [H]

Molecular weight: Translated: 95556; Mature: 95424

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQAQAKYLKDYQAPQFTIETIDLDFNLDGKNTLVKAVSKVKRTSSHTNPLVLDGESLTL
CCCHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
VSVAIDGQAATYHASEGLLSIETSLNEFELTIITQLDPEANSSLEGLYMSDGAYCTQCEA
EEEEECCCEEEEECCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCEEECCCCEEEEHHH
EGFRRITYFLDRPDVLAKYTVRIEADKLAFPFLLSNGNLIEKGELDGGRHYVRWQDPFPK
CCCEEEEEEECCCCEEEEEEEEEEECCEEECEEECCCCEEECCCCCCCCEEEEECCCCCC
PAYLFALVAGDFDLLQDEFITRSHRKVVLQVFVDKGNLHKAHHAMASLKKSMAWDESRFD
HHHEEEEHHCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
LEYDLDIYMIVAVDFFNMGAMENKGLNIFNTKYVLADTLTATDEDYHGIESVVGHEYFHN
EEECCCEEEEEEEHHHCCCCCCCCCCEEEECCEEEEECEECCCCCHHHHHHHHHHHHHHC
WTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIHAIKVIKNQQFAEDSGPMAH
CCCCEEEEHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PIRPESVIEMNNFYTVTVYNKGAEVIRMMHTLLGEAHFQAGMKLYFKRHDGQAVTCDDFV
CCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHH
AAMEDASGIDLTQFRLWYSQAGTPIVTASDSFNADTGTYQLTLKQTLAGCASPLHIPFSL
HHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEHHHHHHHCCCCCCCCEEH
ELLDEKGQSLVNQVLDFTQAEQVFTFEGMRHKPVASLLQDFSAPVKLHYPFEIDQLVHLM
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
RFASSEVARWEASVTLVSQAIWQNVAHLQQHHTMTLDERVKDSFKGALLDEQLDQALMAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
MLAIPSASALIEQTDTVDLDALALAREFVLTELAAYCEDELTALYRSLVNRDCTKARALK
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NQCLNWLSRVSSEAESFVVEQFEKAANMTDSLGALSAANVGSLPCREHLMAMFEARWRDT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PLVMDKWFMLQATHDVEGVIDSLRQLQQHASFSMSNPNRVRSLIGSFAAGNIYQFHRADG
CCEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
KGYEFLTECLISLNKLNPQVAARMVTPLIQFSKFDEARQAKIKACLTRLLALPELSKDLF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
EKVSKALAQ
HHHHHHHCC
>Mature Secondary Structure 
TQAQAKYLKDYQAPQFTIETIDLDFNLDGKNTLVKAVSKVKRTSSHTNPLVLDGESLTL
CCHHHHHHHHCCCCCEEEEEEEEEEECCCHHHHHHHHHHHHHHCCCCCCEEECCCCEEE
VSVAIDGQAATYHASEGLLSIETSLNEFELTIITQLDPEANSSLEGLYMSDGAYCTQCEA
EEEEECCCEEEEECCCCEEEEECCCCEEEEEEEEEECCCCCCCCCCEEECCCCEEEEHHH
EGFRRITYFLDRPDVLAKYTVRIEADKLAFPFLLSNGNLIEKGELDGGRHYVRWQDPFPK
CCCEEEEEEECCCCEEEEEEEEEEECCEEECEEECCCCEEECCCCCCCCEEEEECCCCCC
PAYLFALVAGDFDLLQDEFITRSHRKVVLQVFVDKGNLHKAHHAMASLKKSMAWDESRFD
HHHEEEEHHCCHHHHHHHHHHHHHHHEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCCC
LEYDLDIYMIVAVDFFNMGAMENKGLNIFNTKYVLADTLTATDEDYHGIESVVGHEYFHN
EEECCCEEEEEEEHHHCCCCCCCCCCEEEECCEEEEECEECCCCCHHHHHHHHHHHHHHC
WTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDLGSRAVNRIHAIKVIKNQQFAEDSGPMAH
CCCCEEEEHHHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
PIRPESVIEMNNFYTVTVYNKGAEVIRMMHTLLGEAHFQAGMKLYFKRHDGQAVTCDDFV
CCCCCCEEEECCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEHHHHH
AAMEDASGIDLTQFRLWYSQAGTPIVTASDSFNADTGTYQLTLKQTLAGCASPLHIPFSL
HHHCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCCCEEEEEHHHHHHHCCCCCCCCEEH
ELLDEKGQSLVNQVLDFTQAEQVFTFEGMRHKPVASLLQDFSAPVKLHYPFEIDQLVHLM
HHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCEEEECCCCHHHHHHHH
RFASSEVARWEASVTLVSQAIWQNVAHLQQHHTMTLDERVKDSFKGALLDEQLDQALMAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHH
MLAIPSASALIEQTDTVDLDALALAREFVLTELAAYCEDELTALYRSLVNRDCTKARALK
HHHCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
NQCLNWLSRVSSEAESFVVEQFEKAANMTDSLGALSAANVGSLPCREHLMAMFEARWRDT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCC
PLVMDKWFMLQATHDVEGVIDSLRQLQQHASFSMSNPNRVRSLIGSFAAGNIYQFHRADG
CCEEECEEEEEECCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCEEEEECCCC
KGYEFLTECLISLNKLNPQVAARMVTPLIQFSKFDEARQAKIKACLTRLLALPELSKDLF
CCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCHHHHHHHH
EKVSKALAQ
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2436977; 3549459; 8905232; 9278503; 3018440; 2869947 [H]