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The map label for this gene is dcp [H]

Identifier: 113969867

GI number: 113969867

Start: 1800402

End: 1802549

Strand: Direct

Name: dcp [H]

Synonym: Shewmr4_1525

Alternate gene names: 113969867

Gene position: 1800402-1802549 (Clockwise)

Preceding gene: 113969864

Following gene: 113969868

Centisome position: 38.26

GC content: 48.65

Gene sequence:

>2148_bases
ATGCGTAAGTCTGTTATTACTACTGCCGTGGCCGCGGCATTGTTATTGGGCGCTTGCTCAGAAAAACCGGCAGCCAATAC
TGAGGCCGCCAATGCGGTCGCGACGCAAGCTGCTGCATCGACTCAAGCTGATGCGACCAATGTGTTATTGAGTAAGAGTC
CACTGCAGGATCAAGCTCCGCAGTTTAATCTGATCAAGAGTTCGGATTATGCCCCCGCGTTTGCGCAGGGCATAAAAGAA
CATGAGGCTGAAATTGCCGCCATTATTGCCAATAAACAGGCGCCAACCTTCGAGAATACGATTTTAGCCATGGAAACCTC
GGGTGAGTTGTTAACTCGAGTGTCACGTACCTTCTTCAATCTGGCGGGGTTAATCTCCGACGATGATTTTCAAAAAAACG
AGGCGGACTTAGCGCCTAAGCTGTCGGCTCACCGCGATAACATCTACTTAGATCCAAGTTTATTTGCCCGTGTAGAAACC
GTATATCAACAACGTGCAGGGTTAAATGCCGAAGATAAGCGCTTGGTCGAGTTTTATTACGAGCAGTTTGTACGTGCTGG
GGCCAAATTATCCGATGCCGATAAAGCCAAGATGCGCGACTTTAACGCTGAGTTAGCGACCCTAGCGACTGAGTTTTCTC
AAAACAGCTTAAAGTCATTTAAAGACGATGTGATTGTTGTGACCGACAAAGCACAACTGGACGGTTTATCTGACAGCGAA
ATCGCGACCTTAGCGGCCGCAGCGCAGGCGGCTGGTAAAACGGGTTACCTGATTACCTTAGTGAACACGACTCGTCAGCC
TATTTTAGCCAGTTTAAATAACCGTGAACTGCGCCAAAAAGTCTGGGAAACCTCGGCTCACCGCGCTGTTGCCAGCAATG
GTCCTTTAATCGTGAAGATGGCGCAGCTGCGCGCTAAGAAAGCCAATTTACTCGGCTTTGATACTTGGGCAGCCTACGCC
GTGGCCGACCAAATGGCTAAAACGCCAAGCGCCGTGTATGAAATTTTAGATGACTTGGCGCCTAAAGCGCTGGCTCACGC
TAAGGCCGATGCGGCGGATATCCAAGCTGAAATCAAAAAGGCCGGCGGTAATTTTGAATTACAACCTTGGGATTGGGCTT
ATTACGCCGAGAAAGTGCGTCAGCAAAAATACGCCCTCGATGAGAGCAGCATCAAACCCTACTTTGAGTTTAACTCTGTG
CTGAAGGATGGTTTGTTCTTCGCGATGCACAAACTCTACGGCATCAGCGTTAAACCGCGCACCGATTTACCAGTATGGAA
TAGCGATGTCCTCGCCTTTGAGGTTTTCGATAAAGACAACAGCTCTATTGGTCTGTTCTATCTTGACCCTTATGCCCGTG
AAGGTAAGGGCGGCGGCGCTTGGATGGATGAGTTTGTCACTCAAAGCGGCCTGCTAGGCACTAAGCCTGTGGTGTATAAC
GCACTGAATATCCCGAAACCTGCCGACGGTCCAACCTTGATGACCTTCGATGAAGTGACCACTATGTTCCATGAATTTGG
TCATGCGGTGCACGGTTTATTCTCCAAGGTGAAATACCCGAGTGTGGCAGGTACCTCTACAGCGCGCGACTTTGTGGAGT
TTCCGTCTCAAGTTAACGAAGATTGGAACATTGACCCTGCGGTCATTGCCAATTACGCCAAGCACTACCAAACTGGTGAG
CCTATTCCTAAAGCCTTACTCGATAAAATCTTAGCTTCGAATAAATTTGGTCAAGGTTTTGATACTGTTGAGTATTTAGC
GGCTGCATTACTGGATATGGAATGGCACTCGATTGGTGCCGACACCCAAATCAAAGATGTGGAACAGTTTGAGCATCAAG
TGTTAGCCAAACACGGCCTCGATTTCGCGCCAATTCCACCGCGTTATAAGTCGAGCTATTTTAGCCATGCCTTCTCGGGT
GGCTATTCTGCAGGTTATTACGCTTATCTGTGGACGGAAGTATTTGCCGCCGATGCCTTTGCCTATATGGGCCAACATGG
TGGTTTAAAAGCCGAAAACGGCGATAAGTTCCGTGATGCGGTATTGTCTAAAGGCAACAGCGAAGATCTGATGCAGGATT
ACATCCACTTTACCGGTCAAAAACCCACGACCGATGCCTTATTAAAGCGCCGTGGTTTAGTCGATTAA

Upstream 100 bases:

>100_bases
CCCAAAGCATGCGTCAGTTGGAAGAGAAGCCAAAATCCGTTACTCGCACCTTTCACTTAAAAAATATAAAGACAGGGCAG
TAACACTCTAGGGAGTTCCT

Downstream 100 bases:

>100_bases
ACGATTCATTGTAAAAAGGGCCAAAGGCTTGGTAGGGCAACCTATCAAGCCTTTTTTTACGCTATTGTTTTTCGATAATC
TTTACTCTAAAATCCCGCCA

Product: peptidyl-dipeptidase Dcp

Products: NA

Alternate protein names: Dipeptidyl carboxypeptidase [H]

Number of amino acids: Translated: 715; Mature: 715

Protein sequence:

>715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFENTILAMETSGELLTRVSRTFFNLAGLISDDDFQKNEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQIKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD

Sequences:

>Translated_715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFENTILAMETSGELLTRVSRTFFNLAGLISDDDFQKNEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQIKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
>Mature_715_residues
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAPQFNLIKSSDYAPAFAQGIKE
HEAEIAAIIANKQAPTFENTILAMETSGELLTRVSRTFFNLAGLISDDDFQKNEADLAPKLSAHRDNIYLDPSLFARVET
VYQQRAGLNAEDKRLVEFYYEQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKMAQLRAKKANLLGFDTWAAYA
VADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKKAGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSV
LKDGLFFAMHKLYGISVKPRTDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNEDWNIDPAVIANYAKHYQTGE
PIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGADTQIKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSG
GYSAGYYAYLWTEVFAADAFAYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD

Specific function: Removes dipeptides from the C-termini of N-blocked tripeptides, tetrapeptides and larger peptides [H]

COG id: COG0339

COG function: function code E; Zn-dependent oligopeptidases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M3 family [H]

Homologues:

Organism=Homo sapiens, GI4507491, Length=635, Percent_Identity=29.7637795275591, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI14149738, Length=639, Percent_Identity=29.8904538341158, Blast_Score=225, Evalue=1e-58,
Organism=Homo sapiens, GI156105687, Length=423, Percent_Identity=28.3687943262411, Blast_Score=161, Evalue=2e-39,
Organism=Escherichia coli, GI1787819, Length=675, Percent_Identity=46.5185185185185, Blast_Score=613, Evalue=1e-176,
Organism=Escherichia coli, GI1789913, Length=687, Percent_Identity=33.4788937409025, Blast_Score=360, Evalue=1e-100,
Organism=Caenorhabditis elegans, GI32565901, Length=595, Percent_Identity=23.6974789915966, Blast_Score=111, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71999758, Length=575, Percent_Identity=19.8260869565217, Blast_Score=72, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6319793, Length=593, Percent_Identity=29.0050590219224, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322715, Length=641, Percent_Identity=22.6209048361934, Blast_Score=133, Evalue=1e-31,
Organism=Drosophila melanogaster, GI20129717, Length=395, Percent_Identity=28.8607594936709, Blast_Score=161, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21356111, Length=508, Percent_Identity=25.9842519685039, Blast_Score=151, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001567 [H]

Pfam domain/function: PF01432 Peptidase_M3 [H]

EC number: =3.4.15.5 [H]

Molecular weight: Translated: 78501; Mature: 78501

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCC
QFNLIKSSDYAPAFAQGIKEHEAEIAAIIANKQAPTFENTILAMETSGELLTRVSRTFFN
CCEEEECCCCCHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LAGLISDDDFQKNEADLAPKLSAHRDNIYLDPSLFARVETVYQQRAGLNAEDKRLVEFYY
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
HHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHH
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKM
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
AQLRAKKANLLGFDTWAAYAVADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSVLKDGLFFAMHKLYGISVKPR
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEE
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
DWNIDPAVIANYAKHYQTGEPIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DTQIKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAF
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure
MRKSVITTAVAAALLLGACSEKPAANTEAANAVATQAAASTQADATNVLLSKSPLQDQAP
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHEECCCCCCCCCC
QFNLIKSSDYAPAFAQGIKEHEAEIAAIIANKQAPTFENTILAMETSGELLTRVSRTFFN
CCEEEECCCCCHHHHHHHHHHHHHEEHEEECCCCCCCCCEEEEEECCHHHHHHHHHHHHH
LAGLISDDDFQKNEADLAPKLSAHRDNIYLDPSLFARVETVYQQRAGLNAEDKRLVEFYY
HHHCCCCCCCCCCCCCCCCCCCCCCCCEEECHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
EQFVRAGAKLSDADKAKMRDFNAELATLATEFSQNSLKSFKDDVIVVTDKAQLDGLSDSE
HHHHHCCCCCCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHCCCCCHH
IATLAAAAQAAGKTGYLITLVNTTRQPILASLNNRELRQKVWETSAHRAVASNGPLIVKM
HHHHHHHHHHCCCCCEEEEEECCCCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEEH
AQLRAKKANLLGFDTWAAYAVADQMAKTPSAVYEILDDLAPKALAHAKADAADIQAEIKK
HHHHHHHHCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
AGGNFELQPWDWAYYAEKVRQQKYALDESSIKPYFEFNSVLKDGLFFAMHKLYGISVKPR
CCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCC
TDLPVWNSDVLAFEVFDKDNSSIGLFYLDPYAREGKGGGAWMDEFVTQSGLLGTKPVVYN
CCCCCCCCCEEEEEEECCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHCCCCCCCCHHEE
ALNIPKPADGPTLMTFDEVTTMFHEFGHAVHGLFSKVKYPSVAGTSTARDFVEFPSQVNE
CCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHCCC
DWNIDPAVIANYAKHYQTGEPIPKALLDKILASNKFGQGFDTVEYLAAALLDMEWHSIGA
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCC
DTQIKDVEQFEHQVLAKHGLDFAPIPPRYKSSYFSHAFSGGYSAGYYAYLWTEVFAADAF
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
AYMGQHGGLKAENGDKFRDAVLSKGNSEDLMQDYIHFTGQKPTTDALLKRRGLVD
HHHHCCCCCCCCCCCHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8226676; 9097039; 9278503 [H]