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The map label for this gene is gmhB [H]

Identifier: 113969864

GI number: 113969864

Start: 1789919

End: 1790470

Strand: Direct

Name: gmhB [H]

Synonym: Shewmr4_1522

Alternate gene names: 113969864

Gene position: 1789919-1790470 (Clockwise)

Preceding gene: 113969861

Following gene: 113969867

Centisome position: 38.03

GC content: 47.83

Gene sequence:

>552_bases
GTGGGTACAGTCAATCGAGCCGTATTTTTAGACCGTGATGGTGTGATCAACAAAGATCATGGTTATGTGCATCAGGTGGA
TGACTTTGAATATATAGAAGGTGTGTTTGAAGCCTGCCTCGCCTTAAAGCAAATGGGATACAAATTGGTGGTGGTCACCA
ATCAGTCGGGGATTGCCCGTGGCATGTATACTGAAGATCAATTCCACAGTCTCACCGAATGGATGGATTGGAACTTTGCC
GATAAAGGTGTTGACCTCGATGGCATCTATTATTGCCCGCACCATAATGAAAAAGGTCTCGGTGAATATAAAGTCGATTG
CGATTGCCGCAAGCCAAAACCTGGCATGCTACTCGATGCGGCAAAATTCCTGAAAATCGATTTGTCGCAGTCGGTGATGG
TGGGCGATAAAGCAGACGATATGCTTGCGGCCAAAGAGGCAGGGGTCCCGACGCGTATCCTCGTCCGTACTGGTAAAGCA
ATCGCTGATGATAGTGAGGCGTCTGTCGTGCTCGATAGCATTGCCGATGTGCCGGGATTTTTAAAGAAGTAG

Upstream 100 bases:

>100_bases
TGTCATGTCTCTAACAACTTCGCGGTGCAATTTCTTGCAATGGATGGAATAATAGGGAAATTACGCATTAAGCGCCGTTT
TTAGTGAGTGGAGTAGTACT

Downstream 100 bases:

>100_bases
CTTATCTTGCTATTTAAACCGCGTATCAATCTATTTGAACGGTGAGATTGAGCTCGAACCGAGAGCTTAACAACAAAAAG
TGCGATATTTGCTTTATCGT

Product: D,D-heptose 1,7-bisphosphate phosphatase

Products: NA

Alternate protein names: D-glycero-D-manno-heptose 1,7-bisphosphate phosphatase [H]

Number of amino acids: Translated: 183; Mature: 182

Protein sequence:

>183_residues
MGTVNRAVFLDRDGVINKDHGYVHQVDDFEYIEGVFEACLALKQMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFA
DKGVDLDGIYYCPHHNEKGLGEYKVDCDCRKPKPGMLLDAAKFLKIDLSQSVMVGDKADDMLAAKEAGVPTRILVRTGKA
IADDSEASVVLDSIADVPGFLKK

Sequences:

>Translated_183_residues
MGTVNRAVFLDRDGVINKDHGYVHQVDDFEYIEGVFEACLALKQMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFA
DKGVDLDGIYYCPHHNEKGLGEYKVDCDCRKPKPGMLLDAAKFLKIDLSQSVMVGDKADDMLAAKEAGVPTRILVRTGKA
IADDSEASVVLDSIADVPGFLKK
>Mature_182_residues
GTVNRAVFLDRDGVINKDHGYVHQVDDFEYIEGVFEACLALKQMGYKLVVVTNQSGIARGMYTEDQFHSLTEWMDWNFAD
KGVDLDGIYYCPHHNEKGLGEYKVDCDCRKPKPGMLLDAAKFLKIDLSQSVMVGDKADDMLAAKEAGVPTRILVRTGKAI
ADDSEASVVLDSIADVPGFLKK

Specific function: Converts the D-glycero-beta-D-manno-heptose 1,7- bisphosphate intermediate into D-glycero-beta-D-manno-heptose 1- phosphate by removing the phosphate group at the C-7 position [H]

COG id: COG0241

COG function: function code E; Histidinol phosphatase and related phosphatases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gmhB family [H]

Homologues:

Organism=Escherichia coli, GI1786399, Length=179, Percent_Identity=61.4525139664804, Blast_Score=233, Evalue=5e-63,
Organism=Escherichia coli, GI87082027, Length=148, Percent_Identity=31.0810810810811, Blast_Score=79, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006549
- InterPro:   IPR004446
- InterPro:   IPR006543 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 3.1.1.-

Molecular weight: Translated: 20297; Mature: 20166

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTVNRAVFLDRDGVINKDHGYVHQVDDFEYIEGVFEACLALKQMGYKLVVVTNQSGIAR
CCCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
GMYTEDQFHSLTEWMDWNFADKGVDLDGIYYCPHHNEKGLGEYKVDCDCRKPKPGMLLDA
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEHH
AKFLKIDLSQSVMVGDKADDMLAAKEAGVPTRILVRTGKAIADDSEASVVLDSIADVPGF
HHHEEEECCCCEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHH
LKK
HCC
>Mature Secondary Structure 
GTVNRAVFLDRDGVINKDHGYVHQVDDFEYIEGVFEACLALKQMGYKLVVVTNQSGIAR
CCCCCEEEEECCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCC
GMYTEDQFHSLTEWMDWNFADKGVDLDGIYYCPHHNEKGLGEYKVDCDCRKPKPGMLLDA
CCCCCHHHHHHHHHHCCCCCCCCCCCCEEEECCCCCCCCCCCEEECCCCCCCCCCEEEHH
AKFLKIDLSQSVMVGDKADDMLAAKEAGVPTRILVRTGKAIADDSEASVVLDSIADVPGF
HHHEEEECCCCEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHCCCHH
LKK
HCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301; 12101286 [H]