Click here to switch to the map view.

The map label for this gene is gpwA [H]

Identifier: 113969540

GI number: 113969540

Start: 1399293

End: 1399904

Strand: Direct

Name: gpwA [H]

Synonym: Shewmr4_1196

Alternate gene names: 113969540

Gene position: 1399293-1399904 (Clockwise)

Preceding gene: 113969539

Following gene: 113969541

Centisome position: 29.73

GC content: 44.77

Gene sequence:

>612_bases
ATGATCTCTATATTAGTGAGTGACGTAATAGAGAATAACGAGTTAGCCAATCTTGGCGCGCCCAATGAGAAGGACATTAT
GATGAAACTCCCCTTAGTTATCTTTGCTAGCCTGTTAAGCACTAGCGCATTTGCGGCAACTTGCCCGAGTTATCTGGGTG
TTGAAGTGCGTAAATTGCACTCGGATGAGAAGATTAATCTGTGTGAATTGACTCAGGGCAAGCCAGTGTTACTGGTCAAC
ACTGCGAGTAACTGTGGCTACACTCCGCAATTTAAGGCCCTCGAAGCGCTTCATAAAGAATACAAAGACAAAGGCTTAGT
GGTGATTGGTTTCCCTTCCGATGACTTTTTCCAAGAGGAAAATGATGAAAAAGACACGGCTAAGGTGTGCTACATCAACT
ATGGTGTTACCTTCACTATGCTCGCGACATCGCCCGTGCGAGGCAGCGATGCTAACAGTGTATTCAAATACTTAGGAGAT
AAAGCTGGCTCGCCTAAGTGGAATTTCTACAAGTATGTCGTCAGTGGCGATGGCAATACTGTGCAGCAGTTTAATTCTAA
GGTGAAACCCGATAGTGCCGAGCTTAAGCAGGCAATAGAATCAGTGCTTTAA

Upstream 100 bases:

>100_bases
AATCCTGTCTGCGGTGATGTTAAAGCAGCTCCCTTGAGCTGCTTTTTTTATCGCTTAAGCCAATCGATAACTCGCTGTAG
CTTTTATTTTTTTATTCAAT

Downstream 100 bases:

>100_bases
TGCCCAATTTATTCATTTTACTCATGTTAAGAGGCTACTTTGGCTAGGTTTTCAGGATTATCAAAAGAGATGGGTCACGC
AAAGCGTGGCAAAGTGGGTG

Product: glutathione peroxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 203; Mature: 203

Protein sequence:

>203_residues
MISILVSDVIENNELANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLGVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KAGSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL

Sequences:

>Translated_203_residues
MISILVSDVIENNELANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLGVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KAGSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL
>Mature_203_residues
MISILVSDVIENNELANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLGVEVRKLHSDEKINLCELTQGKPVLLVN
TASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEENDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGD
KAGSPKWNFYKYVVSGDGNTVQQFNSKVKPDSAELKQAIESVL

Specific function: Not Essential For B12 Transport; However, It Is An Auxiliary Component Of The Transport System. [C]

COG id: COG0386

COG function: function code O; Glutathione peroxidase

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glutathione peroxidase family [H]

Homologues:

Organism=Homo sapiens, GI15618997, Length=128, Percent_Identity=35.9375, Blast_Score=82, Evalue=3e-16,
Organism=Homo sapiens, GI192455698, Length=139, Percent_Identity=32.3741007194245, Blast_Score=78, Evalue=5e-15,
Organism=Homo sapiens, GI4557629, Length=141, Percent_Identity=31.2056737588652, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1788003, Length=168, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17535473, Length=139, Percent_Identity=31.6546762589928, Blast_Score=67, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319721, Length=140, Percent_Identity=48.5714285714286, Blast_Score=122, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322228, Length=139, Percent_Identity=43.1654676258993, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6322826, Length=139, Percent_Identity=38.8489208633094, Blast_Score=96, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24656772, Length=146, Percent_Identity=30.8219178082192, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656767, Length=146, Percent_Identity=30.8219178082192, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24656777, Length=146, Percent_Identity=30.8219178082192, Blast_Score=64, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000889
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00255 GSHPx [H]

EC number: =1.11.1.9 [H]

Molecular weight: Translated: 22307; Mature: 22307

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: PS00460 GLUTATHIONE_PEROXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISILVSDVIENNELANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLGVEVRKLH
CCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHEECC
SDEKINLCELTQGKPVLLVNTASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEE
CCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCC
NDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGDKAGSPKWNFYKYVVSGDGNT
CCCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VQQFNSKVKPDSAELKQAIESVL
HHHHCCCCCCCHHHHHHHHHHCC
>Mature Secondary Structure
MISILVSDVIENNELANLGAPNEKDIMMKLPLVIFASLLSTSAFAATCPSYLGVEVRKLH
CCEEEEHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCHHHHCHHHEECC
SDEKINLCELTQGKPVLLVNTASNCGYTPQFKALEALHKEYKDKGLVVIGFPSDDFFQEE
CCCCCCEEEECCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCCHHHCCC
NDEKDTAKVCYINYGVTFTMLATSPVRGSDANSVFKYLGDKAGSPKWNFYKYVVSGDGNT
CCCCCCEEEEEEECCEEEEEEECCCCCCCCHHHHHHHHCCCCCCCCCEEEEEEEECCCCH
VQQFNSKVKPDSAELKQAIESVL
HHHHCCCCCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA