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The map label for this gene is dinB [H]

Identifier: 113969291

GI number: 113969291

Start: 1105048

End: 1106127

Strand: Direct

Name: dinB [H]

Synonym: Shewmr4_0947

Alternate gene names: 113969291

Gene position: 1105048-1106127 (Clockwise)

Preceding gene: 113969290

Following gene: 113969293

Centisome position: 23.48

GC content: 51.3

Gene sequence:

>1080_bases
GTGCGAAAAATCATTCATATCGATATGGATTGCTATTTTGCTGCGGTGGAAATGCGGGATTTTCCCGAATACCGCGGTAA
ACCGCTGGCCGTCGGCGGCAGTCGGGTGCAGCGTGGCGTCATCAGCACTTGTAATTATGAGGCGCGCAAATTTGGCGTGC
GTTCTGCCATGGCGACGGGCTACGCACTGAAATTGTGCCCCAATCTTATCCTCGTTCCCGGTCGTATGCAGGTCTACAAA
GAGGTCTCGCAGCAAATTCGCGCCATATTTTCCCGATACACAGAGTTAATCGAACCGCTATCCCTCGATGAAGCCTATTT
AGATGTTAGCGATTGTAAGCTGTTTAAGGGCTCTGCCACGTTAATCGCCGAGGCGATTCGCCGTGATATTTTGGCCGAAA
CAGGACTGACTGCATCGGCGGGCGTGGCGCCGATTAAATTTCTCGCCAAGGTCGCCTCTGATTTAAATAAACCCAATGGG
CAATGTGTTATCCCACCCGATGAGGTGCCCGAGTTCGTTAAAAGCTTATCCCTGCGGAAAATACCCGGAGTGGGTAAAGT
GACCGCTGAGAAACTGTCTTCGCTAGGCTTAAATACCTGCGCCGATGTGCAGGCTTATCCAAAGCAAGAGTTGATTGCCC
GTTTTGGTAAGTTTGGCGCCGTGTTAGTCGAGCGGGCCCATGGCATCGATGAGCGCGGGATTTCGGTGAGCCGCGAGCGC
AAATCTGTAGGCGTTGAGACCACTCTCGCTCAGGATATTTACACGCTGGAGCAGTGCCAGCAGGTGATGCCTGGATTAAT
CCAAGAGTTGTCCAGCCGTTTAGTGCGAAGCGCTAAGGGAAGGCAAATCCATAAGCAGGTGGTCAAACTTAAATTTAATG
ATTTTAAACAGACCACCATCGAGCATCGTAGTGACGAGGTCTCCGTGGTGATGTTCTATGAGCTACTGAGCCAAGCAATG
GCTAGGCAAGAGGGCCGTGGAATTAGGTTACTCGGGGTTTCTGTTGGACTCGCCGAGACTAAAGACACGCTTTCGCCGCT
CATGGTACGCGAAACTAAGCAGTTGGATTTTGTGTTTTAG

Upstream 100 bases:

>100_bases
GCGCTGACAATCCAAGCGCAAACAGCACCGCGGCAAATTGATAAGTGGCACTTGATTACTGTTTTTATATACAGTATTTT
GAGTGTCGGAGGAATGCAAG

Downstream 100 bases:

>100_bases
TGTTTATCTAATCTGGGCGGCTCTGGCTCAGCGCCAATCTAACCTAGCTAAGTTATGTAAGTTAACGCGATAATCAGCCT
TACGCAGTGCGCAAATAGAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPNLILVPGRMQVYK
EVSQQIRAIFSRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVPEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGAVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLVRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAETKDTLSPLMVRETKQLDFVF

Sequences:

>Translated_359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPNLILVPGRMQVYK
EVSQQIRAIFSRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVPEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGAVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLVRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAETKDTLSPLMVRETKQLDFVF
>Mature_359_residues
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATGYALKLCPNLILVPGRMQVYK
EVSQQIRAIFSRYTELIEPLSLDEAYLDVSDCKLFKGSATLIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNG
QCVIPPDEVPEFVKSLSLRKIPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGAVLVERAHGIDERGISVSRER
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLVRSAKGRQIHKQVVKLKFNDFKQTTIEHRSDEVSVVMFYELLSQAM
ARQEGRGIRLLGVSVGLAETKDTLSPLMVRETKQLDFVF

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=334, Percent_Identity=30.5389221556886, Blast_Score=165, Evalue=5e-41,
Organism=Homo sapiens, GI7706681, Length=335, Percent_Identity=30.4477611940298, Blast_Score=165, Evalue=6e-41,
Organism=Homo sapiens, GI154350220, Length=253, Percent_Identity=33.596837944664, Blast_Score=135, Evalue=7e-32,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI5729982, Length=117, Percent_Identity=40.1709401709402, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786425, Length=355, Percent_Identity=58.0281690140845, Blast_Score=394, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=31.4720812182741, Blast_Score=139, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17537959, Length=288, Percent_Identity=28.8194444444444, Blast_Score=125, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=332, Percent_Identity=28.0120481927711, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI115534089, Length=350, Percent_Identity=24.5714285714286, Blast_Score=80, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324921, Length=207, Percent_Identity=31.4009661835749, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19923006, Length=338, Percent_Identity=31.0650887573964, Blast_Score=160, Evalue=2e-39,
Organism=Drosophila melanogaster, GI21355641, Length=284, Percent_Identity=30.6338028169014, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24644984, Length=284, Percent_Identity=30.6338028169014, Blast_Score=112, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24668444, Length=118, Percent_Identity=38.135593220339, Blast_Score=83, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39836; Mature: 39836

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATG
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHC
YALKLCPNLILVPGRMQVYKEVSQQIRAIFSRYTELIEPLSLDEAYLDVSDCKLFKGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHEECCHHH
LIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNGQCVIPPDEVPEFVKSLSLRK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHC
IPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGAVLVERAHGIDERGISVSRER
CCCCCHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLVRSAKGRQIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EHRSDEVSVVMFYELLSQAMARQEGRGIRLLGVSVGLAETKDTLSPLMVRETKQLDFVF
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MRKIIHIDMDCYFAAVEMRDFPEYRGKPLAVGGSRVQRGVISTCNYEARKFGVRSAMATG
CCEEEEECCHHHEEHHHHHHCHHHCCCEEEECHHHHHHHHHHHCCHHHHHHHHHHHHHHC
YALKLCPNLILVPGRMQVYKEVSQQIRAIFSRYTELIEPLSLDEAYLDVSDCKLFKGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCHHHHHEECCHHH
LIAEAIRRDILAETGLTASAGVAPIKFLAKVASDLNKPNGQCVIPPDEVPEFVKSLSLRK
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHCCHHC
IPGVGKVTAEKLSSLGLNTCADVQAYPKQELIARFGKFGAVLVERAHGIDERGISVSRER
CCCCCHHHHHHHHHCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
KSVGVETTLAQDIYTLEQCQQVMPGLIQELSSRLVRSAKGRQIHKQVVKLKFNDFKQTTI
HHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
EHRSDEVSVVMFYELLSQAMARQEGRGIRLLGVSVGLAETKDTLSPLMVRETKQLDFVF
HHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA