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The map label for this gene is ntrY [H]

Identifier: 113969211

GI number: 113969211

Start: 1019908

End: 1021575

Strand: Direct

Name: ntrY [H]

Synonym: Shewmr4_0867

Alternate gene names: 113969211

Gene position: 1019908-1021575 (Clockwise)

Preceding gene: 113969210

Following gene: 113969212

Centisome position: 21.67

GC content: 48.98

Gene sequence:

>1668_bases
GTGCTACTGCGAACAAAATTAATCATTTATTCAACAGTTTGTTGTGCTTTGGGTGTGTTACTCACCCTAGGCACCATGAG
TTATCGCTCGTCAGTTTCCTCTCTTGTGGAGGATGCTCCGCACACGTTGCCCGATATTACCGTGCCTGAGCTGGATTTGG
CGCAGCTCGAAGATGCGGTGGCCGCAATCGAATCGACGATTAAGGATACTGAGCAATTTCAAAAGGCACTCTCATTGCAG
GAGCGCTTGAAGACAGAGCAAATCAAACACGAGCTACAAAAGTTAGAGCAACTAAAGCAAGAGCAAGTGCAGATTAAGCT
CTATAAGCTCGATCGTTTGAAGGACGGGCTTTTTAGTCCCGCCCCCCATCCTATTGAGGCGCCACCTATGGTTGCGCCGG
TTGAACCTGTGATCCCCGCCGAATTTAGCCTGTCGGAACACACTCAGTCGATGCCAGCAGTATTTGACATGCTGCTGATA
TTGCTGCTGGCCTGTGGTAGCTGCGCGCTTGGGGTTGCTTGGTTTACTCGCCATTTAGCTCGCAGTCTCAATGCCTTAGA
GGTTGGTTTACTCAACTTTAACGACAATGACTTTAGCGTGAGCATTCCGGCAAATGGTGAGGGGCAGCTGAAAGCATTGG
CGGAATTATTCAATGATTCGGCGGCTAAGCTGCGCCAAGAACGGCAATATATTTACCAGCGGGAACTGCTGCTGGATAAA
GTGATTCAAAGTTCTCCGAATGTGATGCTGCTGTTTAACGACCACCAAAAACTCATGTATGCCAACGATGCGGCGCGGCA
TCTTTTTCATATCAAAGGCAAGATGGAAGGCTTGAGCCTCGACGAGCTGCTGCAAGACTTACCCGAAGCGCTTGCCTTGG
CCCTTAAGCAAGAAAAGAGCGGCCTGTTTACCATGGGTGAGGATGATACTGAGACTTGGTATCTGAGCCGTGGCCAGTTT
TTACTGAATAACCAACAACATAACTTAATCTTGCTCAAGCAGATGACCCGAGAACTCAATCGTCAGGAAGTGGCGGTTTG
GAAGAAGGTGATCCGCATTATCAGCCATGAGTTGAATAATTCTGTCGCGCCCATCGCCTCCATGGTGAACTCGGGGCGTT
TACTGACGAAAGATCTCGATAATCCCAAGCTTAAGCTGATATTCGACACTATAGAGAGTCGAACGAATCACTTGAGCCAG
TTTATTTTCAATTATGCGCGCTTTGCTAAACTGCCTTTACCGCAGCGACGTGATGTGCCGTGGCAGCAGCTTATCGAACA
TTTAACCCAACATTATCCTTTTACCTTAGCCAATGAGTTACCCGTAGAGATGGGCTATTTCGACCAAGGGCAAATGGAGC
AGGTTCTGCTGAATTTACTCAAAAATGCCCATGAATCAGGTTCGAATCCCGATGAAGTCACGCTCTCGATTCGCCACCAA
ACCATGGTGGATGGGGCGGGCTTTAGTATCAAAATCGAGGATCGCGGCAGCGGTATGTCCGAGGAAGTGTTAGAACAAGC
CCTATTGCCCTTTTACTCGACTAAACAATCGGGCACGGGGTTAGGTTTGCCCCTTTGCCGCGAGATTATCGAAGCCCACG
ATGGCAGCATTAGCATGCATAATCGCAGCGACGGTGGTCTGTCGGTACATTTGTGGCTGCCGCAATAA

Upstream 100 bases:

>100_bases
TAGGGTTGAGTCGCCAAGCTTTGTATCGCCGCATGGACAAATTTGGCTTAGAGAAGTAACGATTGGCAGCATAATGGGTG
GCGATTAGGCGGGAATTAAC

Downstream 100 bases:

>100_bases
ACCGCCTTTAAGTGTGTATCAAGAGGTTTCACTCCTCAGCCGAATGTATTACCCAAATGGGCTATTTTGCGGTTTTTACC
TTAGCTTTTCGGGCTAATTT

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 555; Mature: 555

Protein sequence:

>555_residues
MLLRTKLIIYSTVCCALGVLLTLGTMSYRSSVSSLVEDAPHTLPDITVPELDLAQLEDAVAAIESTIKDTEQFQKALSLQ
ERLKTEQIKHELQKLEQLKQEQVQIKLYKLDRLKDGLFSPAPHPIEAPPMVAPVEPVIPAEFSLSEHTQSMPAVFDMLLI
LLLACGSCALGVAWFTRHLARSLNALEVGLLNFNDNDFSVSIPANGEGQLKALAELFNDSAAKLRQERQYIYQRELLLDK
VIQSSPNVMLLFNDHQKLMYANDAARHLFHIKGKMEGLSLDELLQDLPEALALALKQEKSGLFTMGEDDTETWYLSRGQF
LLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDLDNPKLKLIFDTIESRTNHLSQ
FIFNYARFAKLPLPQRRDVPWQQLIEHLTQHYPFTLANELPVEMGYFDQGQMEQVLLNLLKNAHESGSNPDEVTLSIRHQ
TMVDGAGFSIKIEDRGSGMSEEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLSVHLWLPQ

Sequences:

>Translated_555_residues
MLLRTKLIIYSTVCCALGVLLTLGTMSYRSSVSSLVEDAPHTLPDITVPELDLAQLEDAVAAIESTIKDTEQFQKALSLQ
ERLKTEQIKHELQKLEQLKQEQVQIKLYKLDRLKDGLFSPAPHPIEAPPMVAPVEPVIPAEFSLSEHTQSMPAVFDMLLI
LLLACGSCALGVAWFTRHLARSLNALEVGLLNFNDNDFSVSIPANGEGQLKALAELFNDSAAKLRQERQYIYQRELLLDK
VIQSSPNVMLLFNDHQKLMYANDAARHLFHIKGKMEGLSLDELLQDLPEALALALKQEKSGLFTMGEDDTETWYLSRGQF
LLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDLDNPKLKLIFDTIESRTNHLSQ
FIFNYARFAKLPLPQRRDVPWQQLIEHLTQHYPFTLANELPVEMGYFDQGQMEQVLLNLLKNAHESGSNPDEVTLSIRHQ
TMVDGAGFSIKIEDRGSGMSEEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLSVHLWLPQ
>Mature_555_residues
MLLRTKLIIYSTVCCALGVLLTLGTMSYRSSVSSLVEDAPHTLPDITVPELDLAQLEDAVAAIESTIKDTEQFQKALSLQ
ERLKTEQIKHELQKLEQLKQEQVQIKLYKLDRLKDGLFSPAPHPIEAPPMVAPVEPVIPAEFSLSEHTQSMPAVFDMLLI
LLLACGSCALGVAWFTRHLARSLNALEVGLLNFNDNDFSVSIPANGEGQLKALAELFNDSAAKLRQERQYIYQRELLLDK
VIQSSPNVMLLFNDHQKLMYANDAARHLFHIKGKMEGLSLDELLQDLPEALALALKQEKSGLFTMGEDDTETWYLSRGQF
LLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNNSVAPIASMVNSGRLLTKDLDNPKLKLIFDTIESRTNHLSQ
FIFNYARFAKLPLPQRRDVPWQQLIEHLTQHYPFTLANELPVEMGYFDQGQMEQVLLNLLKNAHESGSNPDEVTLSIRHQ
TMVDGAGFSIKIEDRGSGMSEEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMHNRSDGGLSVHLWLPQ

Specific function: Member of the two-component regulatory system ntrY/ntrX involved in nitrogen level control. Probably activates ntrX by phosphorylation [H]

COG id: COG5000

COG function: function code T; Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=332, Percent_Identity=26.2048192771084, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790436, Length=121, Percent_Identity=33.0578512396694, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=194, Percent_Identity=28.8659793814433, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788549, Length=244, Percent_Identity=28.2786885245902, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR017232 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 62512; Mature: 62512

Theoretical pI: Translated: 5.58; Mature: 5.58

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLRTKLIIYSTVCCALGVLLTLGTMSYRSSVSSLVEDAPHTLPDITVPELDLAQLEDAV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AAIESTIKDTEQFQKALSLQERLKTEQIKHELQKLEQLKQEQVQIKLYKLDRLKDGLFSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APHPIEAPPMVAPVEPVIPAEFSLSEHTQSMPAVFDMLLILLLACGSCALGVAWFTRHLA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RSLNALEVGLLNFNDNDFSVSIPANGEGQLKALAELFNDSAAKLRQERQYIYQRELLLDK
HCCCHHEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VIQSSPNVMLLFNDHQKLMYANDAARHLFHIKGKMEGLSLDELLQDLPEALALALKQEKS
HHHCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GLFTMGEDDTETWYLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNN
CCEECCCCCCCEEEEECCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVAPIASMVNSGRLLTKDLDNPKLKLIFDTIESRTNHLSQFIFNYARFAKLPLPQRRDVP
CHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WQQLIEHLTQHYPFTLANELPVEMGYFDQGQMEQVLLNLLKNAHESGSNPDEVTLSIRHQ
HHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
TMVDGAGFSIKIEDRGSGMSEEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMH
HEECCCCCEEEEECCCCCCHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEC
NRSDGGLSVHLWLPQ
CCCCCCEEEEEECCC
>Mature Secondary Structure
MLLRTKLIIYSTVCCALGVLLTLGTMSYRSSVSSLVEDAPHTLPDITVPELDLAQLEDAV
CCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AAIESTIKDTEQFQKALSLQERLKTEQIKHELQKLEQLKQEQVQIKLYKLDRLKDGLFSP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
APHPIEAPPMVAPVEPVIPAEFSLSEHTQSMPAVFDMLLILLLACGSCALGVAWFTRHLA
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
RSLNALEVGLLNFNDNDFSVSIPANGEGQLKALAELFNDSAAKLRQERQYIYQRELLLDK
HCCCHHEEEEEEECCCCEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHH
VIQSSPNVMLLFNDHQKLMYANDAARHLFHIKGKMEGLSLDELLQDLPEALALALKQEKS
HHHCCCCEEEEECCCCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCC
GLFTMGEDDTETWYLSRGQFLLNNQQHNLILLKQMTRELNRQEVAVWKKVIRIISHELNN
CCEECCCCCCCEEEEECCEEEECCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
SVAPIASMVNSGRLLTKDLDNPKLKLIFDTIESRTNHLSQFIFNYARFAKLPLPQRRDVP
CHHHHHHHHHCCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
WQQLIEHLTQHYPFTLANELPVEMGYFDQGQMEQVLLNLLKNAHESGSNPDEVTLSIRHQ
HHHHHHHHHHCCCEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEHH
TMVDGAGFSIKIEDRGSGMSEEVLEQALLPFYSTKQSGTGLGLPLCREIIEAHDGSISMH
HEECCCCCEEEEECCCCCCHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHHHCCCCEEEC
NRSDGGLSVHLWLPQ
CCCCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1661370 [H]