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The map label for this gene is cobT [H]

Identifier: 113969186

GI number: 113969186

Start: 997259

End: 998311

Strand: Direct

Name: cobT [H]

Synonym: Shewmr4_0842

Alternate gene names: 113969186

Gene position: 997259-998311 (Clockwise)

Preceding gene: 113969185

Following gene: 113969187

Centisome position: 21.19

GC content: 52.99

Gene sequence:

>1053_bases
ATGTCTCAATCTACCCTGTTATTTCAAATCGAGCCTGCGAGTCGAGCGCAGGATCAGTTTATTCAACAAAAGATCGATCT
GAAGACTAAGCCGCCGGGCGCTCTGGGGTTGTTAGAACCCTTGGCGCTGCAAATTGCCCGCATTCAAGGGCCTAAGCAAT
TAGAGATAGTGAACCCAACCATGTTGGTGTTTGCTGGGGATCATGGGATTGCCGCCGAAGGCGTGTCGATAGCCCCGAGC
GAAGTCACGCGGCAAATGGTGCAAAACTTTGCCCATGGCGGCGCGGCTATCAATGTGTTTTGTCGCCAACTAGGCTTCAA
TCTCGAAGTGATTGATTGCGGTATTTTAACCCCGGTTGAGGGTGTCGAAGGCATTATAGACCAACGCCTTGGCGCCGGCA
CTGGCGCAATTCACTTAGAGCCAGCGATGAGTTTAGCTTGTGTGGACAAGGGCTTTGCCATGGCGCAGGCGTTAATCGAG
CGCCACCACCAAGCGGGTTGTAACTTGGTCGCCTTTGGCGAGATGGGCATAGGCAACACCTCTTCCGCTGCGGCGATTAT
GGCGGCCATCATGCAACTCGATGTGGCCGACTGTGTTGGCCGTGGCACGGGGATCAGTAGCGAAACCTTAGAGCGTAAAC
AGATGCTTATCGAACTCGCACTGCTGTTACATCAGAGTGCGATGACAGGGCCAAAGCAAGTGCTGGCCTGTTTGGGCGGC
TTTGAAATTGTGCAAATGACGGGGGCCATGCTCGCCGCCGCCGAGCGCAAGATGCTGGTCGTGGTGGATGGTTTTATTGC
AACCGCGGCGGCTTTGGTTGCCGTGACTATCAATGCCCATGTGCGGGATTATTTGATTTTTGCCCACCGCTCCGAGGAGC
AAGGTCATCAGCGGATGTTGGAACATTTAAAGGCTAAACCATTGTTATCTTTGGGGCTGAGATTAGGCGAAGGCACGGGC
GCTGCCTTGGCATTACCGTTAATTCAAGCCGCAGTAAATTTTTACAATCAAATGGCGAGTTTTAGTGATGCCGGGATTGA
GGCTGTTGTATGA

Upstream 100 bases:

>100_bases
TTGCGAACGAATAGTTGTAAATGAATAGCTGCGAGCGTATTAGCCAATAAGTTATGAGTAGCGGCTCCACATGGGAGCCT
AAATTGCCACTGGAGCGTGA

Downstream 100 bases:

>100_bases
TGTGCCCTGCTAAGTGTCTTATTTAAAATAATAACTTTTAGCTAACCGTTTTAATCTTAAACCTTGCAGCAAGTGTTAAT
TCACTAAGGATGCTTTATGT

Product: nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase

Products: NA

Alternate protein names: NN:DBI PRT; N(1)-alpha-phosphoribosyltransferase [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSQSTLLFQIEPASRAQDQFIQQKIDLKTKPPGALGLLEPLALQIARIQGPKQLEIVNPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMSLACVDKGFAMAQALIE
RHHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGISSETLERKQMLIELALLLHQSAMTGPKQVLACLGG
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVTINAHVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV

Sequences:

>Translated_350_residues
MSQSTLLFQIEPASRAQDQFIQQKIDLKTKPPGALGLLEPLALQIARIQGPKQLEIVNPTMLVFAGDHGIAAEGVSIAPS
EVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMSLACVDKGFAMAQALIE
RHHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGISSETLERKQMLIELALLLHQSAMTGPKQVLACLGG
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVTINAHVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTG
AALALPLIQAAVNFYNQMASFSDAGIEAVV
>Mature_349_residues
SQSTLLFQIEPASRAQDQFIQQKIDLKTKPPGALGLLEPLALQIARIQGPKQLEIVNPTMLVFAGDHGIAAEGVSIAPSE
VTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVEGVEGIIDQRLGAGTGAIHLEPAMSLACVDKGFAMAQALIER
HHQAGCNLVAFGEMGIGNTSSAAAIMAAIMQLDVADCVGRGTGISSETLERKQMLIELALLLHQSAMTGPKQVLACLGGF
EIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVTINAHVRDYLIFAHRSEEQGHQRMLEHLKAKPLLSLGLRLGEGTGA
ALALPLIQAAVNFYNQMASFSDAGIEAVV

Specific function: Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) [H]

COG id: COG2038

COG function: function code H; NaMN:DMB phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CobT family [H]

Homologues:

Organism=Escherichia coli, GI1788300, Length=326, Percent_Identity=38.3435582822086, Blast_Score=202, Evalue=3e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003200
- InterPro:   IPR023195
- InterPro:   IPR017846 [H]

Pfam domain/function: PF02277 DBI_PRT [H]

EC number: =2.4.2.21 [H]

Molecular weight: Translated: 36950; Mature: 36818

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQSTLLFQIEPASRAQDQFIQQKIDLKTKPPGALGLLEPLALQIARIQGPKQLEIVNPT
CCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCHH
GVEGIIDQRLGAGTGAIHLEPAMSLACVDKGFAMAQALIERHHQAGCNLVAFGEMGIGNT
HHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SSAAAIMAAIMQLDVADCVGRGTGISSETLERKQMLIELALLLHQSAMTGPKQVLACLGG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVTINAHVRDYLIFAHRSEEQGHQRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHH
EHLKAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC
>Mature Secondary Structure 
SQSTLLFQIEPASRAQDQFIQQKIDLKTKPPGALGLLEPLALQIARIQGPKQLEIVNPT
CCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCE
MLVFAGDHGIAAEGVSIAPSEVTRQMVQNFAHGGAAINVFCRQLGFNLEVIDCGILTPVE
EEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCEEEEECCCCCCHH
GVEGIIDQRLGAGTGAIHLEPAMSLACVDKGFAMAQALIERHHQAGCNLVAFGEMGIGNT
HHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCC
SSAAAIMAAIMQLDVADCVGRGTGISSETLERKQMLIELALLLHQSAMTGPKQVLACLGG
CHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCC
FEIVQMTGAMLAAAERKMLVVVDGFIATAAALVAVTINAHVRDYLIFAHRSEEQGHQRML
HHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHHHHHHHHEEEEEEEECCHHHHHHHHH
EHLKAKPLLSLGLRLGEGTGAALALPLIQAAVNFYNQMASFSDAGIEAVV
HHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]