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The map label for this gene is rpoC [H]

Identifier: 113968538

GI number: 113968538

Start: 220305

End: 224522

Strand: Direct

Name: rpoC [H]

Synonym: Shewmr4_0193

Alternate gene names: 113968538

Gene position: 220305-224522 (Clockwise)

Preceding gene: 113968537

Following gene: 113968539

Centisome position: 4.68

GC content: 49.08

Gene sequence:

>4218_bases
GTGAAAGACTTATTAAAGTTTCTGAAACAGCAAAGCAAGACTGAAGAATTTAACGGCATCAAAATTGGTCTGGCATCGCC
TGATCTGATCCGTTCTTGGTCTTTTGGTGAAGTTAAGAAGCCAGAAACCATTAACTACCGTACCTTCAAGCCTGAGCGTG
AAGGTCTGTTCTGTGCGCGTATCTTTGGCCCGGTCAAAGATTACGAATGTTTGTGCGGTAAGTACAAGCGTTTGAAGCAC
CGTGGTGTGATCTGTGAAAAGTGTGGCGTAGAAGTTACCCAGACTAAAGTACGTCGTGAGCGTATGGGTCACATTGAACT
GGCTAGCCCAGTTGCCCACATTTGGTTCTTGAAATCACTGCCGTCCCGTATCGGTTTAATGCTGGACATGACGCTGCGTG
ATATCGAACGCGTACTGTATTTTGAATCTTTCGTCGTGATCGAGCCTGGCATGACCAGCCTTGAACGTGGCCAAATGCTG
ACAGAAGAAAACTATCTGGACGCATTAGAAGAATACGGTGACGAATTCGAAGCTAAGATGGGTGCTGAAGCGGTATTAGA
ACTGCTGCGCGCGATCGATCTCGAAAAAGAAATCGAACAAATGCGTGAAGAGCTGCCATCAATCAACTCTGAGACTCGTC
GCAAGAAAGTGACCAAGCGTCTTAAGTTGATGGAAGCGTTCCACACTTCTGGCAACAAGCCAGAGTGGATGATCTTAAAA
GTACTGCCTGTGTTACCACCTGACTTACGTCCGCTGGTACCGCTCGATGGCGGCCGCTTCGCGACTTCAGATCTGAACGA
TTTGTACCGCCGCGTGATCAACCGTAACAACCGTTTGAAGCGTCTGTTAGATTTAGCTGCGCCGGACATCATCGTACGCA
ACGAAAAGCGTATGTTACAAGAGTCTGTTGATGCGCTATTAGATAACGGTCGTCGTGGTCGTGCTATTACCGGTTCTAAC
AAACGTCCTCTGAAATCTTTGGCCGATATGATCAAAGGTAAACAAGGTCGTTTCCGTCAGAACTTATTAGGTAAGCGTGT
TGACTACTCTGGTCGTTCGGTAATTACCGTAGGTCCTACTTTACGTCTGCACCAATGTGGTCTTCCTAAGAAGATGGCAC
TGGAACTGTTCAAGCCATTCATCTATGGCAAGCTGGAAGGTCGTGGCTTAGCGACAACCATCAAAGCTGCTAAGAAGATG
GTCGAGCGTGAAGTGGCGGAAGTTTGGGACGTTCTGGATGAAGTGATCCGCGAACATCCAGTGATGCTTAACCGTGCACC
AACACTGCACAGACTGGGTATCCAAGCGTTCGAACCTGTACTGATTGAAGGTAAAGCAATCCAGTTACACCCACTCGTTT
GTGCGGCATACAACGCCGACTTCGACGGTGACCAAATGGCGGTACACGTACCGTTAACACTGGAAGCGCAGCTTGAAGCT
CGTGCCCTGATGATGTCAACCAACAACATCCTGTCACCTGCGAACGGCGAGCCTGTAATCACTCCGTCTCAAGACGTGGT
ATTAGGTCTGTACTACACCAGCCGTGAGCGTATCAACGGCCGTGGTGAAGGTATGTACTTTATGTCTGTTGCTGAAGTTG
AAAAAGCTTACGCAACTGGCGCTGCTGAACTGCATGCCCGCGTGAAAGTGCGTATCACTGAAACCGTTATCGGTGACAAT
GGTGAGCGTACTGAACAACGTCGTATCGTAGATACAACAGTGGGTCGTGCTCTGCTGTCACAAATTCTGCCAGCAGGTTT
GTCATTTGATCTGGTTAACCAGAACATGGGCAAAAAGCAAATTTCTAAGCTATTGAACACTTGTTACCGTCAATTAGGTC
TGAAAGATACCGTTATCTTCGCTGACCAACTGATGTACACAGGTTTCCGTTACGCCACTATCTCTGGTGCATCTGTCGGT
ATCGACGACATGGTGATCCCAGCTGAGAAGTACACCTTAGTTGCTGACGCTGAAGCAGAAGTGCTCGAAATTCAAGAGCA
GTTCCAATCAGGTCTGGTGACCGCGGGTGAGCGTTACAACAAAGTAATCGACATCTGGGCAAGTGCGAACGAAAAAGTTT
CTAAAGCGATGATGGAAAACCTGTCAACTGAGACAGTGATTAACCGTGATGGCGTTGAAGAGAAACAAGCTTCGTTCAAC
AGCATTTACATGATGGCCGACTCGGGCGCTCGTGGTAGTGCCGCACAGATCCGTCAGTTAGCGGGTATGCGTGGTCTGAT
GGCGAAACCAGACGGTTCGATCATCGAAACCCCAATCGTGGCGAACTTCCGTGAAGGTCTGAACGTTCTTCAGTACTTCA
TCTCAACCCACGGTGCGCGTAAAGGTCTAGCCGATACCGCATTGAAGACAGCGAACTCGGGTTACCTGACTCGTCGTCTG
GTTGACGTTGCTCAAGACTTAGTGGTCATCGAAGACGATTGTGGTACTCACGAAGGTCTGACAATGAAGCCGCTGATCGA
AGGTGGTGACGTTGTTGAGCCATTACGTGAACGCGTACTGGGTCGTGTGGTTGCTGTTGATGTTATGTACCCAGGTACAG
AAGATGTGCTTGCGCCACGTAACACTCTGCTCGATGAAGCATGGTGTGACAAGTTAGAAGAACACTCAATCGACGAAGTG
ATTGTACGTTCAGTAATTACCTGTGATACCGACTTCGGTGTGTGTGCGGCATGTTATGGCCGTGACTTAGCCCGTGGTCA
CCTGATTAACCACGGCGAAGCTATCGGTGTTGTCGCGGCGCAATCAATCGGTGAACCTGGTACACAGTTAACGATGCGTA
CGTTCCACATCGGTGGTGCGGCATCGAGAGCGTCTGCAGAAAACAACGTTCAAGTGAAGAACTCTGGTTCGTTGAAACTG
CACAACGCTAAGTACGTGACTAACACTGACGGCAAGCTGGTTATCGTTTCTCGTTCTTCTGAACTGGCGATCATCGACGA
ATTAGGTCGTGAGAAAGAGCGTTATAAAGTGCCTTACGGTACTGTGCTCGAGAAGTTAGAAGAAGCATCAGTAGAAGCGG
GCGATATCATCGCTAACTGGGATCCACATACTCACCCAATCATCACTGAAGTGGCGGGTAGTATTAAGTTCGTTGACATG
ATCGACGGCGTGACCATGACTCGTCAAACAGACGAACTGACAGGTCTGTCATCAATCGTGATCCTCGACGTGGGTCAACG
TGGTTCAGCGGGTAAAGAAATGCGCCCAATGATCCGTCTTGTTGGTGCCGACGGTAGCGACCTGATGATCCCAGGTACTG
AAGTGCCGGCACAATACTTCTTACCAGGCAGTGCGATCGTTAACCTTGACGACAATGCGCAAATCGCCGTGGGTGACGCG
TTAGCACGTATTCCACAAGAATCGTCTAAAACACGCGACATCACGGGTGGTCTACCACGCGTTGCTGACCTGTTCGAAGC
CCGTAAGCCAAAAGAGCCAGCTATTCTGGCGGAAATCTCTGGTACCATCTCGTTTGGTAAAGAGACCAAAGGCAAGCGTC
GTCTGGTGATCACACCAGCGGATGGCGGAGAACATTACGAAGAGATGATCCCGAAATGGCGTAACTTAAACGTGTTCGAA
GGTGAAAAAGTCGAACGTGGTGAAGTTATTGCTGACGGTCCAGAGGCGGCGCACGACATTCTGCGTCTACGTGGCATCCA
CAACGTAGCAAACTACATTGTGAATGAAGTACAAGACGTATACCGTCTACAAGGCGTGAAGATCAACGATAAACATATCG
AAGTGATCATCCGTCAAATGCTGCGTAAGTGCGTGATCACCTCTGCGGGTGACAGTGAGTTCTTAGAAGGCGAACAAGTC
GAAGTGTCTCGCGTCAAGATTGCTAACCGCGAACTTGTCGAACAAGGCAAAGTGCCTGCGACCTTCGAACGTGAACTGCT
GGGTATTACCAAAGCGTCTCTGGCAACAGAATCGTTTATCTCTGCAGCATCATTCCAAGAAACGACTCGCGTACTGACAG
AAGCTGCCGTAGGTGGTAAGTCTGATAACTTACGTGGTCTGAAAGAAAACGTAATCGTTGGCCGCCTGATCCCAGCCGGT
ACTGGTTATGCTTATCACAAGACTCGTAACGATGCCCGTGCTAAGAAAGACGAGCCAGTTGTAGTGAATAAGATCACTGC
AAGTGAAGCAGAACAAAATCTCGCAGACCTGTTAAACTTGGCTGGCAGCCAAGATTAA

Upstream 100 bases:

>100_bases
AGTTGGATCAGGAATAAGCGCAGGTATTTAGCCGCGTTTGGCAACAGAATGGTGCTCCGTGAGAGCGGAGCACCCGGTTT
AACTCCTTCAGGAGAGAAAC

Downstream 100 bases:

>100_bases
GTGAACAGTTTGTAACAAAAAGGCGCCAATGGCGCCTTTTTTATTGGAAAATGCCGCAAAAGTTGGCTATTTCTTGACAG
TCAGGCTTTACCTTTCTAAA

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta' [H]

Number of amino acids: Translated: 1405; Mature: 1405

Protein sequence:

>1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATGAAELHARVKVRITETVIGDN
GERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVG
IDDMVIPAEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANWDPHTHPIITEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRLVGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCVITSAGDSEFLEGEQV
EVSRVKIANRELVEQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKITASEAEQNLADLLNLAGSQD

Sequences:

>Translated_1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATGAAELHARVKVRITETVIGDN
GERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVG
IDDMVIPAEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANWDPHTHPIITEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRLVGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCVITSAGDSEFLEGEQV
EVSRVKIANRELVEQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKITASEAEQNLADLLNLAGSQD
>Mature_1405_residues
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCARIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSLPSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQML
TEENYLDALEEYGDEFEAKMGAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILK
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQESVDALLDNGRRGRAITGSN
KRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPTLRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKM
VEREVAEVWDVLDEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATGAAELHARVKVRITETVIGDN
GERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVG
IDDMVIPAEKYTLVADAEAEVLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVLGRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEV
IVRSVITCDTDFGVCAACYGRDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
HNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANWDPHTHPIITEVAGSIKFVDM
IDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRLVGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDA
LARIPQESSKTRDITGGLPRVADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFE
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQMLRKCVITSAGDSEFLEGEQV
EVSRVKIANRELVEQGKVPATFERELLGITKASLATESFISAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAG
TGYAYHKTRNDARAKKDEPVVVNKITASEAEQNLADLLNLAGSQD

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family [H]

Homologues:

Organism=Homo sapiens, GI4505939, Length=917, Percent_Identity=26.2813522355507, Blast_Score=207, Evalue=7e-53,
Organism=Homo sapiens, GI39725938, Length=757, Percent_Identity=26.2879788639366, Blast_Score=159, Evalue=1e-38,
Organism=Homo sapiens, GI103471997, Length=260, Percent_Identity=30, Blast_Score=91, Evalue=8e-18,
Organism=Escherichia coli, GI2367335, Length=1407, Percent_Identity=80.45486851457, Blast_Score=2328, Evalue=0.0,
Organism=Caenorhabditis elegans, GI25145495, Length=690, Percent_Identity=27.1014492753623, Blast_Score=187, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71987878, Length=923, Percent_Identity=24.2686890574215, Blast_Score=176, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6324690, Length=734, Percent_Identity=25.7493188010899, Blast_Score=167, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6320061, Length=541, Percent_Identity=26.8022181146026, Blast_Score=147, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6324917, Length=653, Percent_Identity=23.7366003062787, Blast_Score=126, Evalue=2e-29,
Organism=Drosophila melanogaster, GI17530899, Length=917, Percent_Identity=24.7546346782988, Blast_Score=185, Evalue=2e-46,
Organism=Drosophila melanogaster, GI281360912, Length=882, Percent_Identity=23.469387755102, Blast_Score=165, Evalue=2e-40,
Organism=Drosophila melanogaster, GI17647875, Length=361, Percent_Identity=27.7008310249307, Blast_Score=102, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754 [H]

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 155472; Mature: 155472

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILK
CHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATG
HHHEEECCCCCCCCCCCEEECCCCCEEEEEEEECHHHCCCCCCCEEEEEHHHHHHHHHCC
AAELHARVKVRITETVIGDNGERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQ
HHHEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVGIDDMVIPAEKYTLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCEEECCCCEEEEECCCHH
VLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCHHHEECCCCCCHHHCCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHH
GRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEVIVRSVITCDTDFGVCAACYG
HHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHC
RDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
CHHHCCCCCCCCCEEEEEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCEEE
HNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANW
ECCEEEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCHHHHHHHHHHHCCCCCCEEECC
DPHTHPIITEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRL
CCCCCHHHHHHCCCEEEEHHHCCCEEECCCHHHCCCCEEEEEECCCCCCCCCHHHHHHEE
VGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDALARIPQESSKTRDITGGLPR
ECCCCCCEEECCCCCCHHEECCCCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCC
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCVITSAGDSEFLEGEQVEVSRVKIANRELVEQGKVPATFERELLGITKASLATESFI
HHHHHCCCCCCCHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGYAYHKTRNDARAKKDEPV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCEEECCCCHHCCCCCCCE
VVNKITASEAEQNLADLLNLAGSQD
EEEEECHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKDLLKFLKQQSKTEEFNGIKIGLASPDLIRSWSFGEVKKPETINYRTFKPEREGLFCAR
CHHHHHHHHHHCCCCCCCCEEEECCCCHHHHCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRIGLMLDMTLRDIERVLYFESFVVIEPGMTSLERGQMLTEENYLDALEEYGDEFEAKM
HHHHCHHHHHHHHHHHHHHHHHCEEEECCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHC
GAEAVLELLRAIDLEKEIEQMREELPSINSETRRKKVTKRLKLMEAFHTSGNKPEWMILK
CHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
VLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLDLAAPDIIVRNEKRMLQ
EECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEEECHHHHHH
ESVDALLDNGRRGRAITGSNKRPLKSLADMIKGKQGRFRQNLLGKRVDYSGRSVITVGPT
HHHHHHHHCCCCCCEECCCCCCHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCEEEEECCC
LRLHQCGLPKKMALELFKPFIYGKLEGRGLATTIKAAKKMVEREVAEVWDVLDEVIREHP
EEECCCCCCHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAYNADFDGDQMAVHVPLTLEAQLEA
CEECCCCCHHHHCHHHCCCEEECCCEEEEECEEEEEECCCCCCCCEEEEEEEEEECCHHH
RALMMSTNNILSPANGEPVITPSQDVVLGLYYTSRERINGRGEGMYFMSVAEVEKAYATG
HHHEEECCCCCCCCCCCEEECCCCCEEEEEEEECHHHCCCCCCCEEEEEHHHHHHHHHCC
AAELHARVKVRITETVIGDNGERTEQRRIVDTTVGRALLSQILPAGLSFDLVNQNMGKKQ
HHHEEEEEEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHCCCCCHHH
ISKLLNTCYRQLGLKDTVIFADQLMYTGFRYATISGASVGIDDMVIPAEKYTLVADAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCEEEEEECCCCCCCCCEEECCCCEEEEECCCHH
VLEIQEQFQSGLVTAGERYNKVIDIWASANEKVSKAMMENLSTETVINRDGVEEKQASFN
HHHHHHHHHCCCCCCCHHHCCEEEEECCCCHHHHHHHHHCCCHHHEECCCCCCHHHCCCC
SIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPIVANFREGLNVLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEECCCHHHHHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVAQDLVVIEDDCGTHEGLTMKPLIEGGDVVEPLRERVL
CCHHHHHHHHCCCCHHHHHHHHHHHCEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHH
GRVVAVDVMYPGTEDVLAPRNTLLDEAWCDKLEEHSIDEVIVRSVITCDTDFGVCAACYG
HHEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHC
RDLARGHLINHGEAIGVVAAQSIGEPGTQLTMRTFHIGGAASRASAENNVQVKNSGSLKL
CHHHCCCCCCCCCEEEEEEHHHCCCCCCEEEEEEEEECCCCCCCCCCCCEEEECCCCEEE
HNAKYVTNTDGKLVIVSRSSELAIIDELGREKERYKVPYGTVLEKLEEASVEAGDIIANW
ECCEEEECCCCEEEEEECCCCEEHHHHHCCCHHHEECCHHHHHHHHHHHCCCCCCEEECC
DPHTHPIITEVAGSIKFVDMIDGVTMTRQTDELTGLSSIVILDVGQRGSAGKEMRPMIRL
CCCCCHHHHHHCCCEEEEHHHCCCEEECCCHHHCCCCEEEEEECCCCCCCCCHHHHHHEE
VGADGSDLMIPGTEVPAQYFLPGSAIVNLDDNAQIAVGDALARIPQESSKTRDITGGLPR
ECCCCCCEEECCCCCCHHEECCCCEEEEECCCCEEEECHHHHHCCCCCCCCCCCCCCCHH
VADLFEARKPKEPAILAEISGTISFGKETKGKRRLVITPADGGEHYEEMIPKWRNLNVFE
HHHHHHHCCCCCCEEEEEECCCEECCCCCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCC
GEKVERGEVIADGPEAAHDILRLRGIHNVANYIVNEVQDVYRLQGVKINDKHIEVIIRQM
CCCCCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRKCVITSAGDSEFLEGEQVEVSRVKIANRELVEQGKVPATFERELLGITKASLATESFI
HHHHHCCCCCCCHHCCCCCEEEHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SAASFQETTRVLTEAAVGGKSDNLRGLKENVIVGRLIPAGTGYAYHKTRNDARAKKDEPV
HHHHHHHHHHHHHHHHCCCCCCCCCCHHHCCEEEEEECCCCCCEEECCCCHHCCCCCCCE
VVNKITASEAEQNLADLLNLAGSQD
EEEEECHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA