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The map label for this gene is rpoB [H]

Identifier: 113968537

GI number: 113968537

Start: 216244

End: 220221

Strand: Direct

Name: rpoB [H]

Synonym: Shewmr4_0192

Alternate gene names: 113968537

Gene position: 216244-220221 (Clockwise)

Preceding gene: 113968536

Following gene: 113968538

Centisome position: 4.59

GC content: 47.64

Gene sequence:

>3978_bases
GTGTTGGATATTCCTTACCTTTTGTCTATTCAGTTAGACTCTTTTAAGAAGTTCACCGATCAAGATCCTACCGGTGAGCG
CGGTTTAGAAGCCGCCTTCCGTAGCGTTTTTCCCATCAAGAGCTTTTCTGGTAATTCAGAACTGCAATACGTCAGCTATA
AGCTTGGCGAGCCTGTTTTTGATGTGAAAGAGTGTCAGATCCGTGGTGTTACATATTCAGCGCCACTACGCGTTAAATTA
CGCATGGTGTTGTATGATCGTGAAGCAGCGGCCGGCACTGTAAAAGATATTAAAGAACAAGAAGTCTACATGGGTGATAT
CCCATTAATGACTGACAACGGTACCTTTGTGATCAACGGTACTGAGCGTGTAATCGTATCTCAATTACACCGCAGCCCAG
GCGTGTTCTTTGATCATGACCGTGGTAAAACCCACTCATCAGGTAAGGTGCTGTATAACGCACGTATCATTCCTTACCGT
GGTTCATGGTTAGACTTTGAATTCGACCCTAAAGATGCACTGTTCGTACGTATTGACCGTCGCCGTAAATTACCTGCGAC
CATCATTCTGCGCGCATTAGAGTATTCTACTCAAGAGATCCTCGATCTGTTCTTCGAACGCGTTGAGTTCAAGATCAAGA
AAGATACTCTGGTTATGACCTTAGTACCTGAGCGTCTGCGTGGCGAAACCGCCAGCTACGACATCAAGGATGCTGAAGGC
TCTGTATTGGTTGAAGCTGGCCGTCGTATCACTGCACGCCACATTCGCCAATTAGAAAAAACCAATACCACTGAACTCGA
AGTGCCAGTTGAGTACATCGTGGGCAAATATGCTGCCCAAGATTACATCGATCCGGACACGGGTGAAGTCTTAGTTTCTG
CTAACAGTGAAATCAGCTTAGAAGACTTAGCGAAGTTATCACTGGCAGGCATCAAAGAGCTAAGCACGTTATACATCAAC
GAGCTAGACCACGGTGCTTACATCTCTGACACTCTGCGTATCGATCCAACCACTAACCGCTTAGAAGCGTTAGTTGAGAT
CTACCGCATGATGCGTCCTGGTGAGCCACCAACCAAAGATGCAGCAGAAGCGCTGTTCCAAAACTTATTCTTCAGCGAAG
AACGTTATGACCTGTCTAAAGTAGGTCGTATGAAGTTCAACCGTCGTCTCAGCATTCCTGATGACGAAGGTAGCGGCGTA
CTGTCTAAAGAAGACATCGTTGCAGTAATGAAGAACATCATTCACATCCGTAACGGCTTCGACGAAGTGGACGATATCGA
CCACTTAGGTAACCGTCGAATTCGTTCTGTGGGTGAAATGGCTGAAAACCAATTCCGTGTTGGTCTGGTCCGTGTTGAGC
GCGCCGTGCGTGAACGTCTGTCATTAGGCGATCTAAACGAGCTGATGCCACAAGACTTAATCAACGCTAAGCCAATTTCT
GCCGCAGTGAAAGAGTTCTTCGGTTCTTCTCAGCTGTCACAATTCATGGACCAAAACAACCCGCTGTCAGAAGTAACGCA
TAAGCGTCGTATTTCTGCTCTTGGCCCAGGTGGTTTGACCCGTGAACGTGCAGGCTTCGAAGTCCGCGACGTACACCCAA
CGCACTATGGTCGTTTATGTCCAATTGAGACCCCTGAAGGTCCAAACATTGGTCTAATCAACTCATTAGCGAGCTTTGCC
CGTACTAACTCTTACGGCTTCTTAGAAACCCCATACCGCAAAGTGGTAGACGGTGTGATCACTGACGATGTGGAATACTT
GTCGGCGATTGAAGAAGGTCGTTATGTGATTGCACAGGCGAACATCGAAGTTGACTCACAAGGTCGCATGGTTGAAGAAC
AGATCGCATGTCGTCACAAAGGTGAATCTACCTTTATGCGTGCGTCTGACATTCAATACATGGACGTATCGCCACAACAG
ATCATCTCTGTTGCTGCGTCTCTGATCCCGTTCTTAGAACACGACGACGCGAACCGTGCATTGATGGGTGCGAACATGCA
ACGTCAAGCGGTACCAACACTGAAATCAGAGAAGCCTCTGGTCGGTACGGGTATTGAGCGCACGTTAGCTGTGGACTCCG
GTGTAGTTGTTGCTGCCAAACGTGGCGGTGTGATCGATTACGTTGATGCGAGCCGTATCGTTGTTAAAGTTAATGAAGAC
GAGCTGCGCCCAGGCGAAGCAGGTATCGACATTTACAACCTGACTAAGTACACCCGTTCTAACCAAAACACTTGTATCAA
CCAACGTCCATGTTGTTCAGTTGGTGAGCCAGTGGTTCGTGGTGACGTGTTAGCAGACGGTCCGTCTACTGACTTAGGTG
ACTTAGCCCTTGGTCAGAACATGCGTATCGCATTCATGCCTTGGAACGGTTACAACTTCGAAGACTCGATCTTAATTTCT
GAGCGTGTTGCACAGGAAGACCGTTTCACCACTATCCACATTCAAGAGCTGTCTTGTATCGCTCGTGATACCAAGCTGGG
TAGTGAAGAAATCACTGCTGACATTCCAAACGTAGGTGAATCTGCTCTGTCGAAACTCGACGAGTCAGGTATCGTTTACA
TCGGTGCAGAAGTGAAGGGTGGTGACATTCTGGTTGGTAAAGTTACGCCAAAAGGCGAGACGCAACTGACTCCAGAAGAG
AAGTTACTACGCGCTATCTTCGGTGAGAAAGCGTCTGATGTGAAAGACAGCTCACTGCGTGTACCTAACTCTGTTAAAGG
TACCATCATCGACGTTCAGGTATTTACCCGTGACGGCGTTGAGAAAGACAAACGCGCCATTGAAATCGAAGAAATGCACA
TTGCCCAAGCTCGTAAAGACTTAGGCGAAGAGTTCAAGATCCTTGAAGAAGGCGTATTGAGCCGTGCGCGCAACTTATTA
TTAAGTGCCGGTTTCACTGAAGCACAAATCGCAGCATTGCCACGTAAAGATGTATTGGTTCAAGTTATTGACGATGAAAC
CAAACAAACTGAGCTTGAGCAATTAGCTGAACAGCATGAAGAGCTGAAAGCAGACTTCGATAAGAAGTTTGAAATCAAAC
GTCGCAAGATCACCCAAGGTGATGACTTGGCACCAGGCGTACTGAAGATCGTTAAGGTTTACTTAGCGGTTAAACGTACT
ATCCAACCAGGTGACAAGATGGCGGGTCGTCACGGTAACAAGGGTGTTATCTCTAAGATTAACCCAATTGAAGACATGCC
GTACGACGAGCAAGGCAACCCTGTGGACATCGTATTGAACCCGCTAGGCGTTCCATCACGTATGAACATCGGTCAGGTTC
TTGAAGTTCACTTAGGTGCTGCTGCTAAAGGTATTGGTAACAAGATTGCTGCCATGCTGGAAGATCAGCGCGAGAAGGGA
CTTGCAGAAGTTCGTAGCTACATCAAGCAAGTGTACGAATTAGGTGACGAAGTGCAGCAGCGCGTTGACATCGATTCATT
CACTGACGATGAGTTACTGCGCTTAGCGAACAACCTGAAAGGCGGTATCCCAGTTGCTACGCCAGCCTTCGACGGTGCTA
AAGAGAAAGAGATCAAGCAGATGCTTGAGCTTGCAGGCTTGCCAACCTCTGGTCAGCTGAAATTATTTGATGGTCGTACC
GGTAACGAATTTGAGCGTCCAGTAACTGTAGGTTACATGTACATGCTCAAACTGAACCACTTAGTTGACGATAAGATGCA
CGCCCGTTCTACCGGTTCGTACAGCTTAGTGACTCAACAACCTCTGGGCGGTAAAGCTCAGTTCGGTGGTCAGCGTTTCG
GGGAGATGGAAGTGTGGGCACTCGAAGCATACGGTGCCGCTTATACGCTTCAAGAAATGCTCACCGTGAAATCGGATGAC
GTTAACGGTCGTACTCAGATGTATAAGAACATCGTCGACGGTAACCATCAGATGCAGCCTGGCATGCCAGAGTCCTTCAA
CGTATTACTGAAGGAGATCCGTTCACTCGGTATCAACATCGAGTTGGATCAGGAATAA

Upstream 100 bases:

>100_bases
GAGTTCAGTCTTGGTCACATCTCGCAAGCAGAGGAAACCCATGGTTTACTCCTATTCTGAAAAGAAGCGTATTCGCAAAG
ACTTTGGTAAGCGTCCACAG

Downstream 100 bases:

>100_bases
GCGCAGGTATTTAGCCGCGTTTGGCAACAGAATGGTGCTCCGTGAGAGCGGAGCACCCGGTTTAACTCCTTCAGGAGAGA
AACGTGAAAGACTTATTAAA

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta [H]

Number of amino acids: Translated: 1325; Mature: 1325

Protein sequence:

>1325_residues
MLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKL
RMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
GSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEG
SVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISLEDLAKLSLAGIKELSTLYIN
ELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGV
LSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPIS
AAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFA
RTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQANIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQ
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNED
ELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILIS
ERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLL
LSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRT
IQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKG
LAEVRSYIKQVYELGDEVQQRVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRT
GNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDD
VNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE

Sequences:

>Translated_1325_residues
MLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKL
RMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
GSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEG
SVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISLEDLAKLSLAGIKELSTLYIN
ELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGV
LSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPIS
AAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFA
RTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQANIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQ
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNED
ELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILIS
ERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLL
LSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRT
IQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKG
LAEVRSYIKQVYELGDEVQQRVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRT
GNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDD
VNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE
>Mature_1325_residues
MLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVFDVKECQIRGVTYSAPLRVKL
RMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYR
GSWLDFEFDPKDALFVRIDRRRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEG
SVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISLEDLAKLSLAGIKELSTLYIN
ELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKDAAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGV
LSKEDIVAVMKNIIHIRNGFDEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPIS
AAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLCPIETPEGPNIGLINSLASFA
RTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQANIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQ
IISVAASLIPFLEHDDANRALMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNED
ELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQNMRIAFMPWNGYNFEDSILIS
ERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGESALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEE
KLLRAIFGEKASDVKDSSLRVPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLL
LSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQGDDLAPGVLKIVKVYLAVKRT
IQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLNPLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKG
LAEVRSYIKQVYELGDEVQQRVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRT
GNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDD
VNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINIELDQE

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates [H]

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family [H]

Homologues:

Organism=Homo sapiens, GI33469941, Length=259, Percent_Identity=32.8185328185328, Blast_Score=127, Evalue=1e-28,
Organism=Homo sapiens, GI212286172, Length=259, Percent_Identity=32.8185328185328, Blast_Score=127, Evalue=1e-28,
Organism=Homo sapiens, GI4505941, Length=306, Percent_Identity=29.4117647058824, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI238908503, Length=160, Percent_Identity=34.375, Blast_Score=81, Evalue=6e-15,
Organism=Homo sapiens, GI238908505, Length=160, Percent_Identity=34.375, Blast_Score=81, Evalue=6e-15,
Organism=Escherichia coli, GI1790419, Length=1325, Percent_Identity=79.8490566037736, Blast_Score=2209, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=251, Percent_Identity=31.8725099601594, Blast_Score=113, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17506623, Length=236, Percent_Identity=30.0847457627119, Blast_Score=111, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25144348, Length=304, Percent_Identity=28.2894736842105, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6325267, Length=254, Percent_Identity=31.496062992126, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6324725, Length=312, Percent_Identity=28.525641025641, Blast_Score=114, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6324781, Length=124, Percent_Identity=38.7096774193548, Blast_Score=83, Evalue=3e-16,
Organism=Drosophila melanogaster, GI17647877, Length=300, Percent_Identity=30.3333333333333, Blast_Score=121, Evalue=3e-27,
Organism=Drosophila melanogaster, GI17136446, Length=265, Percent_Identity=32.8301886792453, Blast_Score=113, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17136444, Length=251, Percent_Identity=31.0756972111554, Blast_Score=107, Evalue=5e-23,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724 [H]

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7 [H]

EC number: =2.7.7.6 [H]

Molecular weight: Translated: 147781; Mature: 147781

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
CCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
DVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVING
CCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHHHEEECCCEEEECCCEEEECC
TERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDR
CHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCEEEEEECC
RRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEG
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEEECCEEEEEECCHHHCCCCCCCCCCCCCC
SVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISL
CEEEECCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCCCCH
EDLAKLSLAGIKELSTLYINELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCHHHHHHHHHHHHHHCCCCCCCHH
AAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGF
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPIS
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHH
AAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
HHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCC
PIETPEGPNIGLINSLASFARTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCEEEEEE
NIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRA
CEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCCCCE
LMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNED
EECCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEEEECCCEEEEEECCC
ELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQN
CCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHCCCC
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGE
CEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCHHHCCCCCCCCH
SALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLR
HHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
VPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLL
CCCCCCCEEEEEEEEECCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQG
HCCCCCHHHHHHCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLN
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
PLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKGLAEVRSYIKQVYELGDEVQQ
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRT
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCC
GNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEE
LEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINI
EECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCE
ELDQE
EECCC
>Mature Secondary Structure
MLDIPYLLSIQLDSFKKFTDQDPTGERGLEAAFRSVFPIKSFSGNSELQYVSYKLGEPVF
CCCCCEEEEEEHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCC
DVKECQIRGVTYSAPLRVKLRMVLYDREAAAGTVKDIKEQEVYMGDIPLMTDNGTFVING
CCCCEEEECEEECCCCEEEEEEEEEECCCCCCHHHHHHHHHEEECCCEEEECCCEEEECC
TERVIVSQLHRSPGVFFDHDRGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDALFVRIDR
CHHHHHHHHHCCCCCEEECCCCCCCCCCEEEEEEEEEEECCCEEEEEECCCCEEEEEECC
RRKLPATIILRALEYSTQEILDLFFERVEFKIKKDTLVMTLVPERLRGETASYDIKDAEG
CCCCCHHHHHHHHHHCHHHHHHHHHHHHHEEEECCEEEEEECCHHHCCCCCCCCCCCCCC
SVLVEAGRRITARHIRQLEKTNTTELEVPVEYIVGKYAAQDYIDPDTGEVLVSANSEISL
CEEEECCCHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCCCCCEEEECCCCCCH
EDLAKLSLAGIKELSTLYINELDHGAYISDTLRIDPTTNRLEALVEIYRMMRPGEPPTKD
HHHHHHHHHHHHHHHHHHHHHCCCCCEEECEEEECCCHHHHHHHHHHHHHHCCCCCCCHH
AAEALFQNLFFSEERYDLSKVGRMKFNRRLSIPDDEGSGVLSKEDIVAVMKNIIHIRNGF
HHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCC
DEVDDIDHLGNRRIRSVGEMAENQFRVGLVRVERAVRERLSLGDLNELMPQDLINAKPIS
CHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHH
AAVKEFFGSSQLSQFMDQNNPLSEVTHKRRISALGPGGLTRERAGFEVRDVHPTHYGRLC
HHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCHHHCCCEEEECCCCCCCCCC
PIETPEGPNIGLINSLASFARTNSYGFLETPYRKVVDGVITDDVEYLSAIEEGRYVIAQA
CCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCHHHHHHHHHCCCEEEEEE
NIEVDSQGRMVEEQIACRHKGESTFMRASDIQYMDVSPQQIISVAASLIPFLEHDDANRA
CEEECCCCCHHHHHHHHHCCCCCCEEEECCCEEECCCHHHHHHHHHHHHHHHCCCCCCCE
LMGANMQRQAVPTLKSEKPLVGTGIERTLAVDSGVVVAAKRGGVIDYVDASRIVVKVNED
EECCCCHHHHCCCCCCCCCCCCCCCCCEEEECCCEEEEECCCCEEEEECCCEEEEEECCC
ELRPGEAGIDIYNLTKYTRSNQNTCINQRPCCSVGEPVVRGDVLADGPSTDLGDLALGQN
CCCCCCCCCEEEEHHHHHCCCCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCHHCCCC
MRIAFMPWNGYNFEDSILISERVAQEDRFTTIHIQELSCIARDTKLGSEEITADIPNVGE
CEEEEEECCCCCCCCCEEHHHHHCCCCCEEEEEEHHHHHHHHHCCCCCHHHCCCCCCCCH
SALSKLDESGIVYIGAEVKGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDSSLR
HHHHHCCCCCEEEEEEEECCCCEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
VPNSVKGTIIDVQVFTRDGVEKDKRAIEIEEMHIAQARKDLGEEFKILEEGVLSRARNLL
CCCCCCCEEEEEEEEECCCCCHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSAGFTEAQIAALPRKDVLVQVIDDETKQTELEQLAEQHEELKADFDKKFEIKRRKITQG
HCCCCCHHHHHHCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCC
DDLAPGVLKIVKVYLAVKRTIQPGDKMAGRHGNKGVISKINPIEDMPYDEQGNPVDIVLN
CCCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEE
PLGVPSRMNIGQVLEVHLGAAAKGIGNKIAAMLEDQREKGLAEVRSYIKQVYELGDEVQQ
CCCCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
RVDIDSFTDDELLRLANNLKGGIPVATPAFDGAKEKEIKQMLELAGLPTSGQLKLFDGRT
HCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEEECCC
GNEFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGKAQFGGQRFGEMEVWA
CCCCCCCCHHHHHHHHHHHHHHCCHHHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEE
LEAYGAAYTLQEMLTVKSDDVNGRTQMYKNIVDGNHQMQPGMPESFNVLLKEIRSLGINI
EECCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCE
ELDQE
EECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12368813 [H]