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The map label for this gene is ligD

Identifier: 116696288

GI number: 116696288

Start: 2662859

End: 2665591

Strand: Direct

Name: ligD

Synonym: H16_B2352

Alternate gene names: NA

Gene position: 2662859-2665591 (Clockwise)

Preceding gene: 116696285

Following gene: 116696289

Centisome position: 91.43

GC content: 70.47

Gene sequence:

>2733_bases
ATGGCCAAGACCACGCGACCGACAGCGCCAAAGGATCCCGGCAAACGCCGCGCCGCGGCAAAAGGCGCCGGCAAGCCCAC
CGGCAAGCGCGCCAGCACGGCCCGCCCGGCGGCACGCGGCGCGCCAGCCGCCAAGGCCGCTCCCGCCGCGCTCGACAAAT
ACCGTCGCATGCGCGACTTCGGCGCCACGCCTGAGCCCAGCGGCGCCGCGCGCACCCGCGGCAAGGTGCACAAGCGCGCC
GGCGAGCTTTCCTTCGTGATCCAGAAGCACGCGGCGCGTCGGCTGCACTATGACTTTCGCCTCGAACTCGGCGGCGCGCT
GAAAAGCTGGGCCGTGCCCAAGGGGCCGAGCCTGGACCCGGCCGACAAGCGCATGGCCATCCATGTCGAGGACCATCCGC
TGGACTATGCCGGCTTCGAGGGCGTAATCCCCGCCGGCCACTATGGCGCCGGCACGGTCATCGTCTGGGACCGCGGCACC
TGGTTGCCGGTAGGCGATGCCGAGGCCGGCTACCGCGCCGGCAAGCTGAAGTTCGAGCTGCGCGGTGAAAAGCTGCACGG
TCACTGGACCCTGGTGCGCATGCACGGCAGCCGGCAGAAGGAGCAGGACGCCTGGCTGCTGATCAAGGAGCGCGACGAGA
CCGCCGTGCCGGCATCGGAGTTCGATGTGGTCGAGGCCTTGCCGGACAGCGTGCTGGGCGGCACGCAGCGCAAACCCGCG
GCAAAGCGCGCGAAGTCCGCGCAGCCGCCTGACGAAGCCGCACCAGATGCACACGGCACGGCGAAATCCCTGAAGCCGCC
GCGCGGCGCGCCGCGCGCGGCCTTGCCGCTGGCGCTGGCGCCGCAGCTGGCCACGCTGGTGGAGCAGCCTCCGTCCGACG
CGCAGGCGTGGCGCTACGAGATCAAGTTCGACGGCTACCGGCTGCTGGCCCGCATCGACGGCAAGGATGTGCGCCTGTTC
ACGCGCCAGGGCAACGACTGGACCAGCAAGCTGCGTGCGCTGGCGCGCGACGTCGGCACCCTGGGCCTGCCCGATGGCTG
GCTCGATGGCGAGATCGTGGTGCTCGGCAAGCATGGCGCGACCGACTTCCAGGCGCTGCAGAATGCCTTCGATACCGCGC
GCGTCGAGGGCATCCAGTATTTCGTGTTCGACCTGCCCTACTTTGCCGGCCATGACCTGCGCAAGGTACCGCTGGTGGAG
CGGCGCGCCCTGCTGCGCCGGATCTTCGCGCACAACACCTCGCCGCGCCTGCAGTTCAGCGAGGACTTCGAGGCCGGCCC
TGCCGACATGCTCGAGGCAGCCTGCCGCATGAAGCTTGAAGGCGTGATCGGCAAGCGCGCCGACGCCGCCTATGTCAGCG
CGCGCACCAGTACGTGGATCAAGCTGAAATGCACCTTGCGCCAGGAGTTCGTGGTGGCGGGCTTCACCGACCCGAAGGGC
AGCCGCGCCGGCATCGGCTCGTTGCTGCTTGGCGTGCACGACAGCGGCGGGCGGCTGCGCTACGCGGGCAATGTCGGCAC
CGGCTTCGACGCGCGCACGCTGGGCGCGCTGCGCACGCAGCTGGACGCGTTGCGCGCCGATTCCGCGCCCTTTGAGAACG
TGCCTGCAGGCGTAAAGGGGCACTGGGTGCGGCCAAAGCTGGTGGCCGAGGTCTCGTTCGGCAGCTGGACCCGCGAAGGC
CGCGTGCGCCATGCCGTGTTCCACGGCCTGCGCACCGACAAGCCCGCGCGCGCGGTGTCGGTGGAGCGGCCGGCAACGCC
GGCGGCCAACGGCAAGCCCGCGGCAACCACGGCAAAGCATGCCGGCACACGGCCGAAGGCGGCGGCAAAGCGCACCACCG
CCGCCGGCGGCAAGGTCGCGATCAGCCATGCCGAGCGCGTCATCGACACAGCATCCGGCCTGACCAAGGGCGACCTGGTG
CGCTACTACGAACGCGCCGCGCCGCTGATCCTGCCGCACCTGCGCGGGCGACCGATCGCGATGGTGCGCGCGCCATCGGG
CGTGGGCGGCGAGCAGTTCTTCCAGCGGCATAGCGACACGCTGCGGGTGGACGGCCTCAACGTGCTCGATCCGGGCCTGT
GGCCTGGGCATCCCGCGCTGCTGGAAATCGCGTCGGCCGAAGCCCTGGTGGCCGCGGCACAGCTCAATGTGGTGGAGTTC
CACACCTGGAACGCCGGCAAGCGCAGCATCGAGCGCCCCAACCGCATCGTCTTCGACCTGGACCCGGGCGAAGGCGTGCC
CTGGCCACAAATGCAGGAAGCCGCCGCGCTGATGAAGGCGCTGCTCGATGAACTCGGCCTCGCCAGCTTCCTGAAGACCA
GTGGCGGCAAGGGGCTGCACGTGGTGGTGCCGATCACGCCGCGTGCCGGGTGGGACGAGGTGAAGGCGTTCGCGCATGAC
GCGGTGCGCCATGTCGCCGCCACCGTGCCGCAGCGCTTCGTGGCCAAGAGCGGTCCAAGCAACCGCGTTGGCAAGATTTT
CATCGATTACCTGCGCAATGGCATAGGCGCCACCACGGTGGCGGCATTCTCGGCGCGGGCACGCCCGGGGCTGGGGGTAT
CGATGCCGGTGTGGTGGGAGGAACTCGATAGCCTGCAAGGCGCGGCGCAGTGGACCGTGGCCAATGCCGGCCCGAGGCTC
GACGCCGTGGCGGCCGACGACCCATGGGCGGACTACGCCGAAACCCGGCAGGCGATCACGCGCGCCGCGGCGCGACTGGC
ACGCGCCCGATAG

Upstream 100 bases:

>100_bases
CGCGCATGGGGCTGCCGCCGGGCGCTGTAGGACGGGCGCCGATTTCAGCGGCGGCATGTGCTGCCTAAGCTGGATACATC
CCACCTAACCGGCGACAGCA

Downstream 100 bases:

>100_bases
CCCCCCGTTCCCGCCGGAGATCCACAGCAGTCGCCAAGCGGCACATTTCTTGCCGCATCCCGGTCATGGCACACGGCCCG
GCACCCCCGCCGCGTGCGCC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 910; Mature: 909

Protein sequence:

>910_residues
MAKTTRPTAPKDPGKRRAAAKGAGKPTGKRASTARPAARGAPAAKAAPAALDKYRRMRDFGATPEPSGAARTRGKVHKRA
GELSFVIQKHAARRLHYDFRLELGGALKSWAVPKGPSLDPADKRMAIHVEDHPLDYAGFEGVIPAGHYGAGTVIVWDRGT
WLPVGDAEAGYRAGKLKFELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDETAVPASEFDVVEALPDSVLGGTQRKPA
AKRAKSAQPPDEAAPDAHGTAKSLKPPRGAPRAALPLALAPQLATLVEQPPSDAQAWRYEIKFDGYRLLARIDGKDVRLF
TRQGNDWTSKLRALARDVGTLGLPDGWLDGEIVVLGKHGATDFQALQNAFDTARVEGIQYFVFDLPYFAGHDLRKVPLVE
RRALLRRIFAHNTSPRLQFSEDFEAGPADMLEAACRMKLEGVIGKRADAAYVSARTSTWIKLKCTLRQEFVVAGFTDPKG
SRAGIGSLLLGVHDSGGRLRYAGNVGTGFDARTLGALRTQLDALRADSAPFENVPAGVKGHWVRPKLVAEVSFGSWTREG
RVRHAVFHGLRTDKPARAVSVERPATPAANGKPAATTAKHAGTRPKAAAKRTTAAGGKVAISHAERVIDTASGLTKGDLV
RYYERAAPLILPHLRGRPIAMVRAPSGVGGEQFFQRHSDTLRVDGLNVLDPGLWPGHPALLEIASAEALVAAAQLNVVEF
HTWNAGKRSIERPNRIVFDLDPGEGVPWPQMQEAAALMKALLDELGLASFLKTSGGKGLHVVVPITPRAGWDEVKAFAHD
AVRHVAATVPQRFVAKSGPSNRVGKIFIDYLRNGIGATTVAAFSARARPGLGVSMPVWWEELDSLQGAAQWTVANAGPRL
DAVAADDPWADYAETRQAITRAAARLARAR

Sequences:

>Translated_910_residues
MAKTTRPTAPKDPGKRRAAAKGAGKPTGKRASTARPAARGAPAAKAAPAALDKYRRMRDFGATPEPSGAARTRGKVHKRA
GELSFVIQKHAARRLHYDFRLELGGALKSWAVPKGPSLDPADKRMAIHVEDHPLDYAGFEGVIPAGHYGAGTVIVWDRGT
WLPVGDAEAGYRAGKLKFELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDETAVPASEFDVVEALPDSVLGGTQRKPA
AKRAKSAQPPDEAAPDAHGTAKSLKPPRGAPRAALPLALAPQLATLVEQPPSDAQAWRYEIKFDGYRLLARIDGKDVRLF
TRQGNDWTSKLRALARDVGTLGLPDGWLDGEIVVLGKHGATDFQALQNAFDTARVEGIQYFVFDLPYFAGHDLRKVPLVE
RRALLRRIFAHNTSPRLQFSEDFEAGPADMLEAACRMKLEGVIGKRADAAYVSARTSTWIKLKCTLRQEFVVAGFTDPKG
SRAGIGSLLLGVHDSGGRLRYAGNVGTGFDARTLGALRTQLDALRADSAPFENVPAGVKGHWVRPKLVAEVSFGSWTREG
RVRHAVFHGLRTDKPARAVSVERPATPAANGKPAATTAKHAGTRPKAAAKRTTAAGGKVAISHAERVIDTASGLTKGDLV
RYYERAAPLILPHLRGRPIAMVRAPSGVGGEQFFQRHSDTLRVDGLNVLDPGLWPGHPALLEIASAEALVAAAQLNVVEF
HTWNAGKRSIERPNRIVFDLDPGEGVPWPQMQEAAALMKALLDELGLASFLKTSGGKGLHVVVPITPRAGWDEVKAFAHD
AVRHVAATVPQRFVAKSGPSNRVGKIFIDYLRNGIGATTVAAFSARARPGLGVSMPVWWEELDSLQGAAQWTVANAGPRL
DAVAADDPWADYAETRQAITRAAARLARAR
>Mature_909_residues
AKTTRPTAPKDPGKRRAAAKGAGKPTGKRASTARPAARGAPAAKAAPAALDKYRRMRDFGATPEPSGAARTRGKVHKRAG
ELSFVIQKHAARRLHYDFRLELGGALKSWAVPKGPSLDPADKRMAIHVEDHPLDYAGFEGVIPAGHYGAGTVIVWDRGTW
LPVGDAEAGYRAGKLKFELRGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDETAVPASEFDVVEALPDSVLGGTQRKPAA
KRAKSAQPPDEAAPDAHGTAKSLKPPRGAPRAALPLALAPQLATLVEQPPSDAQAWRYEIKFDGYRLLARIDGKDVRLFT
RQGNDWTSKLRALARDVGTLGLPDGWLDGEIVVLGKHGATDFQALQNAFDTARVEGIQYFVFDLPYFAGHDLRKVPLVER
RALLRRIFAHNTSPRLQFSEDFEAGPADMLEAACRMKLEGVIGKRADAAYVSARTSTWIKLKCTLRQEFVVAGFTDPKGS
RAGIGSLLLGVHDSGGRLRYAGNVGTGFDARTLGALRTQLDALRADSAPFENVPAGVKGHWVRPKLVAEVSFGSWTREGR
VRHAVFHGLRTDKPARAVSVERPATPAANGKPAATTAKHAGTRPKAAAKRTTAAGGKVAISHAERVIDTASGLTKGDLVR
YYERAAPLILPHLRGRPIAMVRAPSGVGGEQFFQRHSDTLRVDGLNVLDPGLWPGHPALLEIASAEALVAAAQLNVVEFH
TWNAGKRSIERPNRIVFDLDPGEGVPWPQMQEAAALMKALLDELGLASFLKTSGGKGLHVVVPITPRAGWDEVKAFAHDA
VRHVAATVPQRFVAKSGPSNRVGKIFIDYLRNGIGATTVAAFSARARPGLGVSMPVWWEELDSLQGAAQWTVANAGPRLD
AVAADDPWADYAETRQAITRAAARLARAR

Specific function: Unknown

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Homo sapiens, GI4557719, Length=290, Percent_Identity=28.6206896551724, Blast_Score=80, Evalue=6e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR014146
- InterPro:   IPR002755
- InterPro:   IPR014144
- InterPro:   IPR014145
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF01896 DNA_primase_S [H]

EC number: NA

Molecular weight: Translated: 98170; Mature: 98039

Theoretical pI: Translated: 10.69; Mature: 10.69

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKTTRPTAPKDPGKRRAAAKGAGKPTGKRASTARPAARGAPAAKAAPAALDKYRRMRDF
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GATPEPSGAARTRGKVHKRAGELSFVIQKHAARRLHYDFRLELGGALKSWAVPKGPSLDP
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCCCCCC
ADKRMAIHVEDHPLDYAGFEGVIPAGHYGAGTVIVWDRGTWLPVGDAEAGYRAGKLKFEL
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCEEEEEE
RGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDETAVPASEFDVVEALPDSVLGGTQRKPA
ECCEECCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCCCCH
AKRAKSAQPPDEAAPDAHGTAKSLKPPRGAPRAALPLALAPQLATLVEQPPSDAQAWRYE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEE
IKFDGYRLLARIDGKDVRLFTRQGNDWTSKLRALARDVGTLGLPDGWLDGEIVVLGKHGA
EEECCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
TDFQALQNAFDTARVEGIQYFVFDLPYFAGHDLRKVPLVERRALLRRIFAHNTSPRLQFS
CHHHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEC
EDFEAGPADMLEAACRMKLEGVIGKRADAAYVSARTSTWIKLKCTLRQEFVVAGFTDPKG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEEEEEEEEEEECCCCCC
SRAGIGSLLLGVHDSGGRLRYAGNVGTGFDARTLGALRTQLDALRADSAPFENVPAGVKG
CCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HWVRPKLVAEVSFGSWTREGRVRHAVFHGLRTDKPARAVSVERPATPAANGKPAATTAKH
CCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHH
AGTRPKAAAKRTTAAGGKVAISHAERVIDTASGLTKGDLVRYYERAAPLILPHLRGRPIA
CCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCEE
MVRAPSGVGGEQFFQRHSDTLRVDGLNVLDPGLWPGHPALLEIASAEALVAAAQLNVVEF
EEECCCCCCHHHHHHHCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEE
HTWNAGKRSIERPNRIVFDLDPGEGVPWPQMQEAAALMKALLDELGLASFLKTSGGKGLH
EECCCCHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VVVPITPRAGWDEVKAFAHDAVRHVAATVPQRFVAKSGPSNRVGKIFIDYLRNGIGATTV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHH
AAFSARARPGLGVSMPVWWEELDSLQGAAQWTVANAGPRLDAVAADDPWADYAETRQAIT
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
RAAARLARAR
HHHHHHHHCC
>Mature Secondary Structure 
AKTTRPTAPKDPGKRRAAAKGAGKPTGKRASTARPAARGAPAAKAAPAALDKYRRMRDF
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHC
GATPEPSGAARTRGKVHKRAGELSFVIQKHAARRLHYDFRLELGGALKSWAVPKGPSLDP
CCCCCCCCCHHHHHHHHHHHCHHHHHHHHHHHHHCCEEEEEEECCCHHHCCCCCCCCCCC
ADKRMAIHVEDHPLDYAGFEGVIPAGHYGAGTVIVWDRGTWLPVGDAEAGYRAGKLKFEL
CCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCEEECCCCCCCCCCCEEEEEE
RGEKLHGHWTLVRMHGSRQKEQDAWLLIKERDETAVPASEFDVVEALPDSVLGGTQRKPA
ECCEECCEEEEEEECCCCCCCCCCEEEEEECCCCCCCCHHHHHHHHCCHHHHCCCCCCCH
AKRAKSAQPPDEAAPDAHGTAKSLKPPRGAPRAALPLALAPQLATLVEQPPSDAQAWRYE
HHHHCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCEEEE
IKFDGYRLLARIDGKDVRLFTRQGNDWTSKLRALARDVGTLGLPDGWLDGEIVVLGKHGA
EEECCEEEEEEECCCEEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEECCCC
TDFQALQNAFDTARVEGIQYFVFDLPYFAGHDLRKVPLVERRALLRRIFAHNTSPRLQFS
CHHHHHHHHHHHHHHCCEEEEEEECCHHCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEC
EDFEAGPADMLEAACRMKLEGVIGKRADAAYVSARTSTWIKLKCTLRQEFVVAGFTDPKG
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCEEEEEEEEEEEEEEEEECCCCCC
SRAGIGSLLLGVHDSGGRLRYAGNVGTGFDARTLGALRTQLDALRADSAPFENVPAGVKG
CCCCCCEEEEEEECCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCC
HWVRPKLVAEVSFGSWTREGRVRHAVFHGLRTDKPARAVSVERPATPAANGKPAATTAKH
CCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCCCCCCEEECCCCCCCCCCCCCCCCHHHH
AGTRPKAAAKRTTAAGGKVAISHAERVIDTASGLTKGDLVRYYERAAPLILPHLRGRPIA
CCCCCCHHHHHHCCCCCEEEHHHHHHHHHHHCCCCHHHHHHHHHHCCCEEECCCCCCCEE
MVRAPSGVGGEQFFQRHSDTLRVDGLNVLDPGLWPGHPALLEIASAEALVAAAQLNVVEF
EEECCCCCCHHHHHHHCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHHHHEEEEEE
HTWNAGKRSIERPNRIVFDLDPGEGVPWPQMQEAAALMKALLDELGLASFLKTSGGKGLH
EECCCCHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEE
VVVPITPRAGWDEVKAFAHDAVRHVAATVPQRFVAKSGPSNRVGKIFIDYLRNGIGATTV
EEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHH
AAFSARARPGLGVSMPVWWEELDSLQGAAQWTVANAGPRLDAVAADDPWADYAETRQAIT
HHHHHCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCCHHHHHHHHHHH
RAAARLARAR
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]